Sjogren's Syndrome: A Guide for the Patient
Muscle biopsies in anti-HMGCR positive patients have a predominant myofibre necrosis pattern. Interestingly, despite this extensive myonecrosis, there appears to be less inflammation and lymphocytic infiltration when compared with biopsies from traditional PM and DM patients. There is generally an absence of CD8+ T cells invading muscle fibres ... ................
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