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Of those positive 95% have dermatomyositis and 3% polymyositis. PCNA Pleomorphic speckled nucleoplasmic staining, with variability in size and brightness of the speckles. 3-6% SLE, very specific. May occur in chronic hepatitis B or C. PM-Scl Nucleolar homogeneous. Myositis-scleroderma overlap (50%-70% of patients with sensitivity). ................
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