Lippincott Williams & Wilkins

List the major drugs of abuse in the U.S. and their acute and chronic effects when abused. ... Cardiac toxicity: all LA are negative inotropic agents. Blood pressure: All cause arteriolar dilatation except for cocaine, which is a vasoconstrictor. Spinal and epidural anesthesia - blockade of sympathetic outflow from the spinal cord may increase ... ................
................