Journal Club Articles - Department of Medicine

Journal Club Articles

1. Twenty-five year follow up for breast cancer incidence and mortality of the

Canadian National Breast Screening Study: Randomized Screening Trial Miller et.al; BMJ 2014

2. Effect of ACEI and ARB on All-Cause Mortality, Cardiovascular Death and

Cardiovascular Events in Patients with Diabetes Mellitus. A Meta-Analysis Cheng et.al; JAMA 2014

3. Age-Adjusted D-Dimer Cutoff Levels to Rule out Pulmonary Embolism. The

ADJUST-PE Study Righini, Van Es et. Al.; JAMA 2014

4. Changes in Mortality after Massachusetts Health Care Reform

Sommers, Long et. Al; Annals of Internal Medicine; May 6th, 2014

5. Health Care-Associated Infection after Red Blood Cell Transfusion. A

Systematic Review and Meta-Analysis Rohde et.al; JAMA 2014

6. Aspirin in Patients Undergoing Noncardiac Surgery

Devereaux et al; NEJM April 2014

7. Albumin Replacement in Patients with Severe Sepsis or Septic Shock

Caironi et al; NEJM April 2014

8. A Randomized Trial of Protocol-Based Care for Early Septic Shock

The ProCESS Investigators; NEJM March 18th, 2014

9. High versus Low Blood-Pressure Target in Patients with Septic Shock

Asfar et.al; NEJM March 18th, 2014

10. Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic

Shock Rivers et.al; NEJM Nov 8th, 2001

11. Cost-Effectiveness of Genotype-Guided and Dual Antiplatelet Therapies in

Acute Coronary Syndrome. Kazi MD, et. Al. Annals of Internal Medicine, Feb 2014

12. Effects of Clopidogrel in Addition to Aspirin in Patients with Acute Coronary

Syndromes without ST-Segment Elevation (The CURE Trial). NEJM 2001

13. Long Term Mortality after Screening for Colorectal Cancer.

Shaukat A, Mongin SJ, Geisser MS, et al. NEJM 2013

14. Upper Airway Stimulation for Obstructive Sleep Apnea.

Strollo, Soose, Maurer et al. NEJM 2014

15. Bariatric Surgery vs. non-surgical treatment for obesity.

Gloy, Bhatt, et al. BMJ 2013

16. Use of procalcitonin to reduce patients' exposure to antibiotics in intensive care

units (PRORATA trial): a multicentre randomised controlled trial Bouadma et al; Lancet, 2010

17. Body-Mass Index and Mortality among Adults with Incident Type 2 Diabetes

Tobias et al; NEJM Jan 16th, 2014

18. 2014 Evidence-Based Guideline for the Management of High Blood Pressure in

Adults. Report From the Panel Members Appointed to the Eighth Joint National Committee (JNC 8) JAMA December 2013

19. Heart Association Task Force on Practice Guidelines Cardiovascular Risk in

Adults: A Report of the American College of Cardiology/American 2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Circulation 2013

20. Worsening Trends in the Management and Treatment of Back Pain

JAMA 2013

21. Effects of Vitamin D supplements on bone mineral density: A systematic review

and meta-analysis

22. Combined Angiotensin Inhibition for the Treatment of Diabetic Nephropathy

(NEJM). November 2013

23. Effects of Losartan on Renal and Cardiovascular Outcomes in Patients with

Type 2 Diabetes and Nephropathy. REENAL Study (NEJM) 2001

24. Combined Angiotensin Inhibition for the Treatment of Diabetic Nephropathy

(NEJM). November 2013

25. Effects of Losartan on Renal and Cardiovascular Outcomes in Patients with

Type 2 Diabetes and Nephropathy. REENAL Study (NEJM) 2001

26. Aggressive Fluid and Sodium Restriction in Acute Decompensated Heart

Failure JAMA, June 2013

27. Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL

Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF) The Lancet, June 1999

28. Short-term vs Conventional Glucocorticoid Therapy in Acute Exacerbations of

Chronic Obstructive Pulmonary Disease. The REDUCE Randomized Clinical Trial. JAMA, May 2013

29. Effect of Home Blood Pressure Telemonitoring and Pharmacist Management on

Blood Pressure Control: A Cluster Randomized Clinical Trial Margolis et. al; JAMA July 3, 2013

30. Therapies for Active Rheumatoid Arthritis after Methotrexate Failure

O'Dell et al; NEJM July 25, 2013

31. Diagnostic Blood Loss From Phlebotomy and Hospital-Acquired Anemia

During Acute Myocardial Infarction Salisbury et al; Arch Intern Med; October 10, 2011

32. "Effect of hormone replacement therapy on cardiovascular events in recently

postmenopausal women" BMJ

33. "Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal

Women" (results from the Women's Health Initiative) JAMA

34. "Associations Between Reduced Hospital Length of Stay and 30 Day

Readmission Rate & Mortality" Annals of Internal Medicine

35. Dietary and Supplemental Calcium Intake and Cardiovascular Disease

Mortality The National Institutes of Health

36. Blood Pressure and Mortality in U.S. Veterans with Chronic Kidney Disease

Annals of Internal Medicine

37. Cardiovascular Effects of Intensive Lifestyle Intervention in Type 2 Diabetes

The New England Journal of Medicine

38. Association Between Chlorthalidone Treatment of Systolic Hypertension and

Long-term Survival JAMA, December 21, 2011

39. Screening for Lung Cancer with Low-Dose Computed Tomography: A

Systematic Review to Update the U.S. Preventive Services Task Force Recommendation Annals of Internal Medicine

40. Twenty-five year follow up for breast cancer incidence and mortality of the

Canadian National Breast Screening Study: Randomized Screening Trial Miller et.al; BMJ 2014

41. Effect of ACEI and ARB on All-Cause Mortality, Cardiovascular Death and

Cardiovascular Events in Patients with Diabetes Mellitus. A Meta-Analysis Cheng et.al; JAMA 2014

42. Twenty-five year follow up for breast cancer incidence and mortality of the

Canadian National Breast Screening Study: Randomized Screening Trial Miller et.al; BMJ 2014

43. Effect of ACEI and ARB on All-Cause Mortality, Cardiovascular Death and

Cardiovascular Events in Patients with Diabetes Mellitus. A Meta-Analysis Cheng et.al; JAMA 2014

44. Simvastatin for the Prevention of Exacerbations in Moderate-to-Severe COPD

Criner et. al NEJM June 14, 2014

45. Atrial Fibrillation in Patients with Cryptogenic Stroke

Gladstone et. al

NEJM June 26, 2014

46. Once weekly Dalbvancin versus conventional therapy for skin infection

Boucher, et. al NEJM June 5th, 2014

47. Pregnancy Incidence and Outcomes Among Women Receiving Pre-exposure

Prophylaxis for HIV Prevention: A Randomized Clinical Trial Nelly R. Mugo, MBChB, MPH1,2,3; et. al



48. Telecare Collaborative Management of Chronic Pain in Primary Care: A

Randomized Clinical Trial Kurt Kroenke, MD1,2,3; Erin E. Krebs, MD4,5; Jingwei Wu, MS6; Zhangsheng Yu, PhD6; Neale R. Chumbler, PhD7; Matthew J. Bair, MD1,2,3



49. Efficacy of Varenicline Combined With Nicotine Replacement Therapy vs

Varenicline Alone for Smoking Cessation: A Randomized Clinical Trial Coenraad F. N. Koegelenberg, MD, PhD1; et.al



50. Early Palliative Care for Patients with Metastatic Non?Small-Cell Lung Cancer

Jennifer S. Temel, M.D., Joseph A. Greer, Ph.D., et.al N Engl J Med 2010; 363:733-742August 19, 2010DOI: 10.1056/NEJMoa1000678

51. Dabigatran versus Warfarin in Patients with Atrial Fibrillation (RE-LY Trial)

Stuart J. Connolly, M.D., Michael D. Ezekowitz, M.B., Ch.B., et.al and the RE-LY Steering Committee and Investigators

N Engl J Med 2009; 361:1139-1151 September 17, 2009

52. Vancomycin, Metronidazole, or Tolevamer for Clostridium difficile Infection:

Results from Two Multinational, Randomized, Controlled Trials

Stuart Johnson, Thomas Louie, et. al for the Polymer Alternative for CDI Treatment (PACT) investigators

Clinical Infectious Diseases; July 2014

53. The CHA2DS2-VASc score identifies those patients with atrial fibrillation and a

CHADS2 score of 1 who are unlikely to benefit from oral anticoagulant therapy Michiel Coppens, John W. Eikelboom et. Al European Heart Journal, September 2012

54. The Risk of Melanoma in Airline Pilots and Cabin Crew

Martina Sanlorenzo, MD et.al JAMA Dermatol. Published online September 03, 2014

55. Cardiovascular Risk and Events in 17 Low, Middle and High-Income Countries

S. Yusuf et.al NEJM, August 28, 2014

56. Angiotensin-Neprilysin Inhibition versus Enalapril in Heart Failure

J.J. McMurray et. al NEJM, September 11th, 2014

57. The Risk of Melanoma in Airline Pilots and Cabin Crew

Martina Sanlorenzo, MD et. al JAMA Dermatol. Published online September 3, 214

58. Cardiovascular Risk and Events in 17 Low, Middle and High-Income Countries

S. Yusuf et. al NEJM, August 28, 2014

59. Angiotensin-Neprilysin Inhibition versus Enalapril in Heart Failure

J.J. McMurray et. al NEJM, September 11, 2014

60. A Controlled Trial of Renal Denervation for Resistant Hypertension

Deepak L. Bhatt, M.D., M.P.H., David E. Kandzari, M.D et.al for the SYMPLICITY HTN-3 Investigators

NEJM, March 29th, 2014

61. Canagliflozin Compared With Sitagliptin for Patients With Type 2 Diabetes

who do not have Adequate Glycemic Control With Metformin Plus Sulfonylurea G. Schernthaner, J. Gross et.al

Diabetes Care, April 5, 2013

62. Bariatric Surgery versus Intensive Medical Therapy for Diabetes -- 3-Year

Outcomes Philip R. Schauer, M.D., Deepak L. Bhatt, M.D., M.P.H., et.al for the STAMPEDE Investigators

NEJM, March 31, 2014

63. Multitarget Stool DNA Testing for Colorectal-Cancer Screening

Thomas F. Imperiale, et. Al NEJM April 3rd, 2014

64. A Randomized Trial of Rectal Indomethacin to Prevent Post-ERCP Pancreatitis

B. Joseph Elmunzer, et. al NEJM April 12, 2012

65. Ledipasvir and Sofosbuvir for 8 or 12 Weeks for Chronic HCV without

Cirrhosis Kris V. Kowdley, et. al NEJM May 15, 2014

66. Goal-Directed Resuscitation for Patients with Early Septic Shock

The ARISE Investigators and the ANZICS Clinical Trials Group* October 1st, 2014

67. Fractional Flow Reserve?Guided PCI for Stable Coronary Artery Disease

Bernard De Bruyne, M.D., Ph.D. et.al NEJM September 2014

68. Effects of Extended-Release Niacin with Laropiprant in High-Risk Patients

The HPS2-THRIVE Collaborative Group* NEJM July 2014

69. Low-Dose Aspirin for Primary Prevention of Cardiovascular Events in

Japanese Patients 60 years or Older with Atherosclerotic Risk Factors Y. Ikeda et. al, JAMA, November 17, 2014

70. Tamoxifen for prevention of breast cancer: extended long-term follow-up of the

IBIS-I breast cancer prevention trial J. Cuzick et.al, Lancet, December 2014 (14)71171-4/abstract

71. A Randomized Trial of Low-Dose Aspirin in the Primary Prevention of

Cardiovascular Disease in Women P. Ridker et.al, NEJM, March 200

72. The Effectiveness and Risks of Long-Term Opioid Therapy for Chronic Pain:

A Systematic Review for a National Institutes of Health Pathways to Prevention Workshop Roger Chou, MD et. Al Annals of Internal Medicine, Feb 17th, 2015

73. Cost-Effectiveness of Hypertension Therapy According to 2014 Guidelines

Andrew E. Moran, M.D., M.P.H., Michelle C. Odden, Ph.D., et.al N Engl J Med January 29, 2015

74. Perioperative Atrial Fibrillation and the Long-term Risk of Ischemic Stroke

Gino Gialdini, MD1; Katherine Nearing, MD2; et.al JAMA, August 13th, 2015

75. Continuous Proton Pump Inhibitor Therapy and the Associated Risk of

Recurrent Clostridium difficile Infection Emily G. McDonald, MD et.al

JAMA, March 2, 2015

76. Association of NSAID Use With Risk of Bleeding and Cardiovascular Events in

Patients Receiving Antithrombotic Therapy After Myocardial Infarction Anne-Marie Schjerning Olsen, MD et.al

JAMA Feb 24, 2015

77. Thrombolysis for Pulmonary Embolism and Risk of All-Cause Mortality,

Major Bleeding, and Intracranial Hemorrhage A Meta-analysis Saurav Chatterjee, MD et.al JAMA, June 18, 2014

78. Antibiotic Treatment Strategies for Community-Acquired Pneumonia in

Adults

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