Women’s health Concerns
WOMEN¡¯S
HEALTH
CONCERNS
Natalie Blagowidow. M.D.
Gynecologic Issues and EhlersDanlos Syndrome/Hypermobility
EDS is associated with a higher frequency of
some common gynecologic problems.
? EDS is associated with some rare gynecologic
disorders.
? Pubertal maturation can worsen symptoms
associated with EDS.
?
Gynecologic Issues and Ehlers
Danlos Syndrome/Hypermobility
? Menstruation
? Menorrhagia
? Dysmenorrhea
? Abnormal menstrual cycle
? Dyspareunia
? Vulvar Disorders
? Pelvic Organ Prolapse
Puberty and EDS
?
Symptoms of EDS can become worse with puberty,
or can begin at puberty
? Hugon-Rodin 2016 series of 386 women with
hypermobile type EDS.
? 52% who had prepubertal EDS symptoms (chronic
pain, fatigue) became worse with puberty.
? 17% developed symptoms of EDS with puberty
Hormones and EDS
? Conflicting data on effects of hormones on connective tissue,
joint laxity, and tendons
? Estriol decreases the formation of collagen in tendons
following exercise
? Joint laxity increases during pregnancy
? Studies (Non EDS)
? Heitz: Increased ACL laxity in luteal phase
? Park: Increased knee laxity during ovulation in some, but no
difference in hormone levels among all (N=26)
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