Attachment: Extract from Clinical Evaluation: Panobinostat ...

The PPK analysis was also based on data from 14 studies, including all studies in the pooled PK analysis apart from Studies X2101 and X2105 (that is, the hepatic and renal impairment studies), and 2 studies not included in the pooled analysis (that is, E2214, a Phase II study in Hodgkin's Lymphoma, and B1201, a small study in 4 Japanese subjects with T-cell lymphoma). ................
................