New Product Introduction in the Pharmaceutical Industry

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New Product Introduction in the Pharmaceutical Industry

Hansen, Klaus Reinholdt Nyhuus

Publication date: 2014 Document Version Publisher's PDF, also known as Version of record Link back to DTU Orbit

Citation (APA): Hansen, K. R. N. (2014). New Product Introduction in the Pharmaceutical Industry. DTU Management Engineering.

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New Product Introduction in the Pharmaceutical Industry

by Klaus Reinholdt Nyhuus Hansen

PhD thesis, Technical University of Denmark

DTU Management Engineering i

New Product Introduction in the Pharmaceutical Industry

PhD thesis Klaus Reinholdt Nyhuus Hansen October 2013 ISBN: 978-87-92706-31-7

Technical University of Denmark DTU Management Engineering Produktionstorvet 424 DK-2800 Kongens Lyngby Denmark

Tel: + 45 4525 4800 E-mail: phd@man.dtu.dk Printer: Schultz Grafisk A/S

Supervisors:

Professor Lars Hvam Operations Management, Production and Service Management DTU Management Engineering Technical University of Denmark Kongens Lyngby, Denmark

Professor Martin Grunow Production and Supply Chain Management TUM School of Management Technische Universit?t M?nchen Munich, Germany

Professor Renzo Akkerman Operations Management and Technology TUM School of Management Technische Universit?t M?nchen Munich, Germany

Professor Rafiqul Gani Computer Aided Process Engineering Centre Department of Chemical and Biochemical Engineering Technical University of Denmark Kongens Lyngby, Denmark

Assessment Committee:

Associate Professor Peter Jacobsen Operations Management, Production and Service Management DTU Management Engineering Technical University of Denmark Kongens Lyngby, Denmark

Professor Jan Olhager Department of Industrial Management and Logistics Faculty of Engineering Lund University Lund, Sweden

Senior Research Associate J?zsef V?ncza Deputy Head of the Research Laboratory of Engineering and Management Intelligence Computer and Automation Research Institute Hungarian Academy of Sciences Budapest, Hungary

Preface

This dissertation represents research performed by the author from September 2009 to July 2013 and has been submitted to DTU Management Engineering, Technical University of Denmark in fulfillment of the requirements for achieving a PhD degree. The research has been carried out at DTU Management Engineering and at TU M?nchen in conjunction with a visiting scholar position there. The content mainly consists of the latest versions of the scientific publications produced during the PhD study, which have all been submitted for review or published. The project has been supervised by Professor Lars Hvam, Professor Martin Grunow, Professor Renzo Akkerman and Professor Rafiqul Gani. The project has been financed by DTU Management Engineering as part of their research program.

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Acknowledgements

Though I am proud to have produced the work presented here by myself, it would not have been possible without having the support of numerous people. People, who believed in me and showed me the way when things seemed hopeless.

First and foremost, I owe a huge thanks to Professor Martin Grunow, who has acted as my main supervisor. He helped me formulate the project and kept me on my track, when I was straying. I have the utmost professional respect for him and I am time and again impressed with his keen perception, to-the-point comments and sharp questions in such a wide range of topics, that I find myself left in awe.

I have also been lucky to have professor Renzo Akkerman as my official supervisor after Martin moved to M?nchen. I have been glad for our MAN Diesel project, which has provided a nice diversion for my project from time to time. I am impressed with your insight and how fast to translate that into results. With our open and informal collaboration, I have considered you more a friend than a supervisor.

It was a pleasure to be invited into the CAPEC group, which was only possible due to the kindness of Professor Rafiqul Gani, who also acted as co-supervisor. I have enjoyed taking part in all the events I have participated in and I have learned a lot both in relation to my project and about process system engineering. I have only the best memories of the people from CAPEC.

Two of the most important people for doing a Ph.D. have for me been Christina and Monika, who have helped me with all the administrative work; often more than required of them. Their help has been invaluable in navigating the rules and regulations of DTU and TUM.

There are so many colleagues, that I have in some way or another worked with at both DTU and TUM. Some have provided social relief while others have contributed to my project. A huge appreciation goes out to especially Ole, Marie, Lykke, Thordis, Pelle, Andreas, Peter and Lars from DTU Management Engineering and Daniel, Sina, Rado, Philip, Bryndis and Verena from TUM School of Management and especially Poorya Farahani, who I moved from DTU to TUM with.

All my dear friends in Herning, Copenhagen and M?nchen who I have been spending time with, talking to, joking with and playing floorball with. You have given me a respite by allowing me the chance to think about other things than my thesis.

My full appreciation I give to my parents, whose comforting phone calls have always supported me more than you know. Having your love means I never feel truly alone; not even when sitting alone and working late at night.

Finally to my love, Elli, who has supported me through the tough final part of my thesis. Having you by my side means the world to me and I look forward to spending much more time with you. I am so glad for having met you.

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