American Association for Cancer Research
Ajulemic acid (AJA) is a synthetic analogue of a tetrahydrocannabinol metabolite. AJA inhibits the promoter activity of Interleukin-8, a pro-inflammatory cytokine. ... An increase in local endocannabinoids or the administration of either OEA or PEA can inhibit the response to nicotine (but not cocaine or morphine) in the reward centers of the ... ................
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