_ CURRICULUM VITAE



CURRICULUM VITAENAME:Harumi Jyonouchi, M. D.ADDRESS:Division of Pulmonary, Allergy/Immunology, and Infectious DiseasesDepartment of Pediatrics, New Jersey Medical School - UMDNJF570A MSB, 185 South Orange Ave.Newark, NJ 07101-1709EDUCATION:Yokohama City University - Premedical1972School of Medicine, Yokohama, JapanYokohama City University - M. D.1976School of Medicine, Yokohama, JapanPOSTDOCTORAL TRAINING:Showa University - Jr. Resident/Pediatrics1976-1977Fujigaoka Hospital, 2-30 Fujigaoka, Midori-KuYokohama, Japan"- Sr. Resident/Pediatrics1977-1978"- Jr. Pediatrician and1978-1980Teaching Assistant POSITIONS HELD:Sloan-Kettering Institute for Cancer Research1980-1981Visiting Research FellowNew York, New YorkSloan-Kettering Institute for Cancer Research1981-1982Research FellowNew York, New YorkOklahoma Medical Research Foundation1982-1985Sr. Research ScientistOklahoma City, OklahomaOklahoma Children's Memorial Hospital1983-1985Fellow in Pediatric ImmunologyOklahoma City, OklahomaAll Children's Hospital 1985Immunology FellowSt. Petersburg, FloridaAll Children's Hospital1986Special Fellow (rotation in generalPediatrics to fulfill the requirementsfor the Board of Pediatrics)St. Petersburg, FloridaUniversity of South Florida1987-1988All Children's HospitalAllergy/Immunology FellowSt. Petersburg, FloridaAll Children's Hospital/University of South Florida1988-1989Bone Marrow Transplant PhysicianClinical Assistant ProfessorSt. Petersburg, Florida University of South Florida 1989-1991All Children's HospitalDepartment of Pediatrics/St. PetersburgAssistant Professor of PediatricsSt. Petersburg, FloridaAll Children's Hospital1989-1991Assistant Director Immunoparameter Laboratory St. Petersburg, FloridaUniversity of Minnesota1991-1999Department of PediatricsAssistant ProfessorMinneapolis, MinnesotaUniversity of Minnesota1999-2002Department of PediatricsAssociate ProfessorMinneapolis, MinnesotaUniversity of MinnesotaCombined Medicine/Pediatrics Allergy/Immunology FellowshipCo-directorMinneapolis, Minnesota1995-2002New Jersey Medical School, University of Medicine and Dentistry of New Jersey (UMDNJ)Division of Pulmonary, Allergy/Immunology, and Infectious DiseasesDepartment of PediatricsAssociate ProfessorNewark, NJ2002-presentLICENSES:ECFMG Certificate1982FLEX1984State of Oklahoma1984State of Florida1987Board of Pediatrics1989Recertified in Pediatrics 1991, 1995, and 2001State of Minnesota1991Board of Allergy and Immunology1993, 2003State of New Jersey2002HONORS:Graduation of Yokohama City University, School of MedicineTop of the class1976Fellowship, Leukemia Society of America, Inc.1982-1984Sr. Fellowship, Leukemia Society of America, Inc. 1984-1986University of MinnesotaUniversity Children's Foundation Scholar Award1993The second place award for The Nestlé Clinical Nutrition Award 1997for Enternal NutritionThe Award for appreciation of contributions in making a difference in the lives of the family and children affected by autism from MN State Representative of ‘Unlocking Autism”2002COSAC – Health Care Provider of the Year Award2006PROFESSIONAL SOCIETIES/Committee:Member, American Medical Association1984-PresentMember, American Association of Immunologists1985-PresentMember, New York Academy of Science1986-PresentMember, Society of Experimental Biology1989-Present and MedicineFellow, American Academy of Pediatrics1990-PresentMember, Clinical Immunology Society1991-PresentMember, Society of American Cancer Research1991-2009Member, Society of Mucosal Immunity1993-PresentMember, Society of Pediatric Research1993-PresentMember, American Academy of Allergy and1994-present Immunology Review committee, Center for Scientific Review (NIH)ZRG1 BNP July 29-30, 1999 ZAT 1CJuly 11-12, 2000 NCCAM study sectionNov. 2000, Feb. 2001, Oct. 2001 ZAT 1C (Dietary supplements)May, 2001Review committee, Congressional Directed Medical Research Program (CDMRP)Autism Research Program2009October, 2009Autism Research Program2010August, 2010Editorial BoardChief Editor - eMedicine (Pediatrics Section) 2007 - presentJ Clin Med Res2009-2011PUBLICATIONS:Peer-reviewed articles:Jyonouchi H and Yamaguchi M: A case of neonatal hyperbilirubinemia secondary due to Rh incompatibility. (in Japanese) J Pediatr Practice 40:2008-2011, 1977.Jyonouchi H, Yanagisawa N, and Yamaguchi M: Hereditary spherocytosis requiring exchange transfusion during the neonatal period with special reference to the morphological studies of HS erythrocytes. (in Japanese) Acta Paediatr JPN 20:654-658, 1978.Jyonouchi H, Yanagisawa N, and Soneda Y: A case of neonatal gastric rupture complicating with congenital diaphragm eventration. (in Japanese) Jap J Pediatr 31:395-398, 1978.Yamaguchi M, Shioda S, Jyonouchi H, Yamada K, and Ishikawa A: Infectious mononucleosis in siblings. (in Japanese) Jap J Pediatr 31:2431-2435, 1978.Jyonouchi H, Shioda S, Yamaguchi M, Yamada K, Ishikawa A, and Ito M: Clinical studies of infectious mononucleosis. (in Japanese) Jap J Pediatr 31:2436-2442, 1978.Yamaguchi M, Jyonouchi H, Sata T, Yokoi K, Yanagisawa N, Yamada K, and Ishikawa A: Clinical and laboratory studies on mycoplasma pneumonia. (in Japanese) Pediatrics of Japan 19:313-319, 1978.Jyonouchi H, Yanagisawa N, Ishikawa A, and Ishihara K: One pedigree of hereditary spherocytosis (HS): Scanning electron microscopic studies of HS erythrocytes in vitro. (in Japanese) J Clin Electron Microsc 12:91-105, 1979.Jyonouchi H, Kurokawa Y, and Ishidawa A: Studies of RBC 2, 3-DPG in MCLS. (in Japanese) Igaku No Ayumi 109:86-88, 1979.Jyonouchi H: Studies of RBC 2, 3-DPG levels in Childhood. 1. Studies on healthy children and low birth weight babies. (in Japanese) J Showa Med Assoc 39:373-379, 1979.Jyonouchi H, Yanagisawa N, Ishikawa A, and Ishihara K: Scanning electromicroscopic studies on the erythrocytes of hereditary spherocytosis III. Effect of propranolol-a beta blocking agent on the erythrocyte of hereditary spherocytosis. J Clin Electron Microsc 12:5-6, 1979.Yamaguchi J, Isoyama K, Fujita Y, Jyonouchi H, Hanawa H, Yanagisawa N, Yamada K, and Ishikawa A: Clinical studies on the complication of mycoplasma pneumonia. (in Japanese) Jap J Infect Dis 54:173-179, 1980.Jyonouchi H, Yokoi K, and Ishikawa A: A congenital bronchobiliary fistula. Acta Paediatr JPN (in Japanese) 84:1270-1277, 1980.Yamaguchi M and Jyonouchi H: Two cases of male Turner Syndrome. J Showa Med Assoc 40:76-82, 1980.Jyonouchi H and Yoshio T: A case of vascular purpura complicating with remarkable facial edema. (in Japanese) Pediatrics of Japan 21:1981.Jyonouchi H, Kincade PW, Good RA, and Fernandes G: Reciprocal transfer of abnormalities in clonable B lymphocytes and myeloid progenitors between NZB and DBA/2 mice. J Immunol 127:1232-1235, 1981.Jyonouchi H, Kincade PW, and Good RA: Immunosuppression of marrow B lymphocytes by administration of Corynebacterium parvum in mice. J Immunol 127:2502-2507, 1981.Jyonouchi H, Cyong JC, Fernandes G, Day NK, and Good RA: Alteration of murine serum lipase activity after allogeneic bone marrow transplantation. J Clin Immunol Immunopathol 22:94-104, 1982.Jyonouchi H, Kincade PW, Landreth KS, Lee G, Good RA, and Gershwin ME: Age-dependent deficiency of B lymphocyte lineage precursors in NZB mice. J Exp Med 155:1665-1678, 1982.Jyonouchi H and Kincade PW: Changes in B lineage cell populations in liver and spleen of neonatal mice. J Immunol 130:1616-1621, 1983.Jyonouchi H, Kincade PW, Good RA, and Gershwin ME: B lymphocyte lineage cells in newborn and very young NZB mice. Evidence for regulatory disorders affecting B cell formation. J Immunol 131:2219-2225, 1983.Jyonouchi H, Kincade PW, and Misra HP: Analysis of the effects of erythrocytes on mitogen-dependent clonal proliferation of murine B lymphocytes. Cell Immunol 83:189-198, 1984.Jyonouchi H and Kincade PW: Precocious and enhanced functional maturation of B lineage cells in New Zealand Black mice during embryonic development. J Exp Med 159:1277-1282, 1984.Jyonouchi H, Kincade PW, and Good RA: Age-dependent changes in B lymphocyte lineage cell populations of autoimmune prone BXSB mice. J Immunol 134:858-864, 1985.Jyonouchi H, Kimmel MD, Lee G, Kincade PW, and Good RA: Humoral factors in very young NZB mice that enhance the maturation of normal B cell precursors. Partial Purification and characterization. J Immunol 135:1891-1899, 1985.Jyonouchi H, Voss RM, and Good RA: IL-1 like activities present in murine amniotic fluid. A significantly larger amount of IL-1 like activity is present in the amniotic fluid of autoimmune NZB mice. J Immunol 138:3300-3307, 1987.Jyonouchi H, Voss RM, and Good RA: The presence of autoantibodies specific for NZB serum factors in adult NZB mice and the establishment of monoclonal antibodies against these humoral factors. Cell Immunol 113:158-174, 1988.Jyonouchi H, Voss RM, and Good RA: Up-regulation and down-regulation of cell surface and mRNA expression of CD5 antigen by various humoral factors on murine 70Z/3 pre-B cell leukemia cell line. IL-4 down-regulates CD5 antigen expression. Cell Immunol 130, 66-78, 1990.Jyonouchi H, Voss RM, and Good RA: NZB serum factor (NZB-SF): B precursor cell maturation factor identified in murine lupus. I. Identification of 60-kDa glycoprotein as the major component from both spleen cell supernatant and serum. Cell Immunol 132:223-235, 1991.Jyonouchi H, Voss RM, and Good RA: NZB serum factor (NZB-SF) - B precursor cell maturation factor: II, In vivo effects of NZB-SF or mAb against NZB SF on B lineage cell population. J Clin Immunol Immunopathol 59:388-397, 1991.Jyonouchi H, Voss RM, Krishna S, Urval K, Sjahli H, Welty PB, and Good RA: Soluble Fce R II levels in normal children and patients with immunodeficiency diseases. J Allergy Clin Immunol 87:965-970, 1991.Jyonouchi H, Hill RJ, Tomita Y, and Good RA: Studies of immunomodulating actions of carotenoids. I. Effects of b-carotene and astaxanthin on murine lymphocyte functions and cell surface marker expression in in vitro culture system. Nutr Cancer 16:93-105, 1991.Jyonouchi H, Voss RM, and Good RA: Zn depletion modifies CD5 expression by 7OZ/3 murine pre-B leukemia cell line. Proc Soci Exp Biol Med 198:818-825, 1991.Jyonouchi H, Hill RJ, and Good RA: RNA/nucleotides enhances antibody production in vitro and is moderately mitogenic to murine spleen lymphocytes. Proc Soci Exp Biol Med 200:101-108, 1992.Jyonouchi H, Zhang L, and Tomita Y: Studies of Immunomodulating Actions of Carotenoids. II. Astaxanthin enhances in vitro antibody production to T-dependent antigens without facilitating polyclonal B cell activation. Nutr Cancer 19:269-280, 1993.Jyonouchi H, Zhang L, and Tomita Y: Studies of immunomodulating actions of RNA/nucleotides. RNA/nucleotides enhance in vitro Ig production by human peripheral blood mononuclear cells in response to T dependent stimuli. Ped Res 33:458-465, 1993.Jyonouchi H, Zhang L, Georgieff M, and Tomita Y: Immunomodulating actions of nucleotides. Enhancement of Ig production by human cord blood lymphocytes. Ped Res 34:565-571, 1993Jyonouchi H, Hill RJ, Voss RM, and Ishii E: Immunomodulating actions of RNA and nucleotides on murine lymphocytes in vitro. Augmentation of antibody production to T dependent antigens and expansion of T helper cells. J Nutr Immunol 2(2):5-24, 1993.Tomita Y, Jyonouchi H, Engelman R, Day NK, and Good RA: Preventive action of carotenoids on the development of autoimmunity in MRL-lpr/lpr mice. J Autoimmunity 16:95-102, 1993.Jyonouchi H, Zhang L, and Tomita Y: RNA/nucleotides enhance in vitro antibody and immunoglobulin production to T-dependent antigen but do not facilitate polyclonal B cell activation in both normal and autoimmune-prone NZB strains of mice. J Nutr Immunol 2 (3): 5-22, 1993.Jyonouchi H, Zhang L, Gross M, and Tomita Y.: Immunomodulating actions of carotenoid: Enhancement of in vivo and in vitro antibody (Ab) production to T-dependent antigens (TD-Ag). Nutr Cancer 21:47-58, 1994.Jyonouchi H: Nucleotide actions on humoral immune responses. J Nutr 124:138S-143S, 1994.Loechelt BJ, Egeler M, Filipovich AH, Jyonouchi H, and Shapiro RS: Immunosuppression: an alternative maintenance therapy for familial hemophagocytic lymphohistiocytosis (FEL). Med Ped Oncol 22:325-328, 1994.Jyonouchi H, Zhang L, Tomita Y, and Yokoyama H: Nucleotide-free diet impairs T-helper cell functions for antibody production in normal C57Bl/6 mice. J Nutr 124: 475-484, 1994.Jyonouchi H, Sun S, and Gross MD: Biological actions of carotenoids: astaxanthin, a carotenoid without vitamin A activity, enhances in vitro Ig production by human peripheral blood mononuclear cells. Nutr Cancer 23:171-183, 1995Jyonouchi H, Zhang L, Sun S, and Yokoyama H: Polynucleotides can compensate for impaired T-dependent antibody production induced by a nucleotide-free diet both in vivo and in vitro in C57Bl/6 mice, but mononucleotide/nucleoside mixture (OGVI) is effective only in vivo. J. Nutr. 125:1578-1586, 1995 Jyonouchi H, Sun S, Tomita Y, and Gross MD: Astaxanthin, a carotenoid without vitamin A activity, augments antibody responses with T-helper clones in response to suboptimal Ag challenges. J. Nutr. 125:2483-2492, 1995.Jyonouchi H, Sun S, Goodman D, Yokoyama H, and Sato S: Dietary fatty acid modulates actions of nucleotides on humoral immune responses. Nutrition 11:437-443, 1995.Jyonouchi H, Sun S, and Tomita Y: Actions of ?-carotene on T-helper cell functions for antibody production. J. Nutr. Immunol. 3 (4): 21-34, 1995.Jyonouchi H and Sun S.: Effects of Orally supplemented mononucleotide mixture on T-dependent humoral immunity in C57BL/6 mice fed a nucleotide-free diet. J. Nutr. 126:1586-1593, 1996.Jyonouchi H, Sun S, and Sato S: A nucleotide-free diet suppresses antigen-driven cytokine production by primed T cells: effects of supplemental nucleotides and dietary fatty acids. Nutrition 12: 608-615, 1996. Jyonouchi H, Sun S, Mizokami M, and Gross MD: Effects of Various Carotenoids on Cloned, Effector-stage T-helper Cell Activity. Nutr. Cancer 26:313-324, 1996Jyonouchi H and Sun S: The actions of polynucleotides on effector stage cloned T-helper cells differ in each T-helper cell subset and depend on antigen concentration. J. Nutr. 127:411-417, 1997.Jyonouchi H, Sun S, Mizokami M, and Ingbar DH: Cell density and antioxidant vitamins determine the effects of hyperoxia on proliferation and death of MDCK epithelial cells. Nutr Cancer 28:115-124, 1997.Jyonouchi H, Sun S, Kennedy CA, Kajander, KC, and Rimell FL: IgG antibody levels in the sinus, ear, and airway in a rabbit model of sinusitis with Bacteroides Archives of Otolaryngology-Head and Neck Surgery. 124:767-772, 1998Jyonouchi H, Sun S, Chareancholvanich S, and Ingbar DH: The effects of hyperoxic injury and antioxidant vitamins on death and proliferation of human small airway epithelial cells. Am. J. Resp. Cell Mol. Biol. 19:426-436, 1998.Jyonouchi H, Sun S, Iijima K., Wong M., and Hecht, SS.: Effects of anti-7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene on human small airway epithelial cells and the protective effects of myo-inositol. Carcinogenesis. 20: 139-145, 1999.Kennedy CA, Jyonouchi H, Kajander KC, Sun S, and Rimell FL: Middle ear changes associated with chronic anaerobic sinusitis in rabbits. Laryngoscope 109: 498-503, 1999.Jyonouchi H, Sun S, Kennedy CA, Roche A, Kajander KC, Miller J, Germaine G, , and Rimell FL: The localized sinus inflammation in a rabbit sinusitis model induced by Bacteroides fragilis is accompanied by rigorous immune responses. Otolaryngology-Head and Neck Surgery. 120: 869-875, 1999.Iijima K, Sun S, Cyong JC, and Jyonouchi H: Juzen-Taiho-To, a Japanese herbal medicine, modulates type 1 and type 2 T cell responses in old BALB/c mice. Am J Chinese Med 17:191-203, 1999.Jyonouchi H. Airway Epithelium and apoptosis. Apoptosis 4:407-417, 1999.Jyonouchi H, Sun S, Iijima K, and Gross MD: Anti-tumor activity of astaxanthin and its mode of action. Nutr. Cancer 36: 59-65, 2000.Jyonouchi H, Sun S, and Rimell FL: Cytokine production by sinus lavage, bronchial lavage, and blood mononuclear cells in chronic sinusitis with or without atopy. Archives of Otolaryngology-Head and Neck Surgery 126: 522-528, 2000Jyonouchi H, Sun S, Kennedy CA, and Rimell FL: Interferon- levels in the sinus, ear, and airway in a rabbit sinusitis model induced by Bacteroides inoculation. Archives of Otolaryngology-Head and Neck Surgery 126: 529-532, 2000Jyonouchi H, Sun S, Abiru T, Whinship, T, and Kuchan, MJ: Dietary nucleotides modulate antigen-specific type 1 and type 2 T cell responses in young C57BL/6 mice. Nutrition 16: 442-446, 2000.Gollob JA, Veenstra KG, Jyonouchi, H, Kelly AM, Ferrieri P, Panka DJ, Altare F, Casanova JL, Fieschi C, Frank DA, and Mier JW. Impairment of STAT Activation by IL-12 in a Patient with Atypical Mycobacterial and Staphylococcal Infections. J. Immunol. 163: 4120-4126. 2000.Jyonouchi H, Sun S, Winship T, and Kuchan MJ: Dietary nucleotides modulate type 1 vs. type 2 T cell responses against ovalbumin in young BALB/c mice. J. Nutr. 131: 1165-1170, 2001Jyonouchi H: Immunomodulating actions of dietary nucleotides – any clinical implication? (Review). Recent Res. Develo. Allergy & Clin. Immunol. 1: 121-128, 2001.Jyonouchi H, Sun S, K. Porter VA, and Cornfield DN: Polycyclic aromatic hydrocarbon (PAH) diol epoxides increase cytosolic Ca2+ concentrations of human small airway epithelial cells. Am J Res Cell Mol Biol. 25: 78-83. 2001Jyonouchi H, Sun S, Le H.: Proinflammatory and regulatory cytokine production associated with innate and adaptive immune responses in children with autism spectrum disorders and developmental regression. J Neuroimmunol. 120: 170-179, 2001Jyonouchi H, Sun S, Le H, and Rimell, FD: Evidence of dysregulated cytokine production by sinus lavage and peripheral blood mononuclear cells in patients with treatment-resistant chronic rhinosinusitis. Arch Otolaryngol Head Neck Surg. 127: 1488-1494. 2001Jyonouchi H, Sun S, and Itokazu N: Innate immunity associated with inflammatory responses and cytokine production against common dietary proteins in patients with autism spectrum disorders. Neuropsychobiology 46: 76-84, 2002.Jyonouchi H, Sun S, Whiship T, and Kuchan MJ: Dietary ribonucleotides increase antigen-specific type 1 T-helper cells in the regional draining lymph nodes in young BALB/cJ mice. Nutrition. 19: 41-46, 2003Jyonouchi H, Sun S, Kelly A, and Rimell FL: The effects of exogenous interferon-γ (IFN-γ) on patients with treatment-resistant chronic rhinosinusitis and dysregulated IFN-γ production – A pilot study. Arch Otolaryngol Head Neck Surg 129: 563-569, 2003.Jyonouchi H, Geng L, Ruby A, and Zimmerman-Bier, B: Dysregulated Innate Immune Responses in Young Children with Autism Spectrum Disorders (ASD): Their Relationship to Gastrointestinal (GI) Symptoms and Dietary Intervention. Neuropsychobiology 2005;51:77-85 (DOI: 10.1159/000084164)Jyonouchi H, Geng L, Ruby A, Reddy C, and Zimmerman-Bier, B: Evaluation of possible association between gastrointestinal (GI) symptoms and cytokine production against common dietary proteins (DPs) in children with autism spectrum disorders (ASD). J. Pediatrics 146: 605-610, 2005.Zimmerman AW, Jyonouchi H, Comi AM, Connors SL, Milstien S, Varsou A, and Heyes MP. CSF AND SERUM MARKERS OF INFLAMMATION IN AUTISM Ped Neurology 33: 195-201, 2005.Jyonouchi H, Lien KW, Aguila H, Spinnato, GG, Sabharwal S, and Pletcher BA: Garre’s osteomyelitis and sarcoid dermatitis in a patient with DiGeorge syndrome. Eur. J. Pediatrics 2006; 165:370-374.Ward CM, Jyonouchi H, Kotenko S, Patel R, Aguila H, McSherry G, Dashefsky B, and Holland SM: Adjunctive treatment of disseminated MAC infection with interferon alpha-2b in a patient with complete interferon-gamma receptor R1 defect. Eur. J. Pediatr 166:981-985, 2007.Ward CM, Geng L, and Jyonouchi H: Fetal sensitization to milk protein and wheat: milk protein and wheat-specific TNF-α production by umbilical cord blood cells and subsequent decline of TNF-α but not IL-10 production by peripheral blood mononuclear cells following dietary intervention. J. Pediatr Allergy Immunol 18: 276-280, 2007.Jyonouchi H, Geng L, Toruner GA, Vinekar K, Feng D, Fitzgerald-Bocarsly P: Monozygous twins with microdeletion syndrome involving BTK, DDPA, and two other genes; evidence of intact dendritic cell development and TLR responses. Eur J Pediatr 67:317-321, 2008.Jyonouchi H. Non-IgE mediated food allergy. Inflammation and Allergy Drug Discovery. Inflamm Allergy Drug Targets. 2008 3:173-80.Jyonouchi H, Geng L, Cushing-Ruby A, Quraishi H: Impact of innate immunity in a subset of children with autism spectrum disorders: a case control study. Jyonouchi H Food Allergy and Autism Spectrum Disorders: Is There a Link? Curr Allergy Asthma Reports 9:194-201, 2009.Jyonouchi H, Geng L, Cushing-Ruby A, Monteiro I. Aberrant responses to TLR agonists in pediatric IBD patients: possible association with increased production of Th1/Th17 cytokines in response to candida, a luminal antigen. J. Ped J Allergy Immunol on line publication first 2009.Timothy Buie, MD; Daniel B. Campbell, PhD; George J. Fuchs III, MD; Glenn T. Furuta, MD; Joseph Levy, MD; Judy Van de Water, PhD; Agnes H. Whitaker, MD; Dan Atkins, MD; Margaret L. Bauman, MD; Arthur L. Beaudet, MD; Edward G. Carr, PhD; Michael D. Gershon, MD; Susan L. Hyman, MD; Pipop Jirapinyo, MD; Harumi Jyonouchi, MD; Koorosh Kooros, MD; Rafail Kushak, MD, PhD; Pat Levitt, PhD; Susan E. Levy, MD; Jeffery D. Lewis, MD; Katherine F. Murray, BSN, RN; Marvin R. Natowicz, MD, PhD; Aderbal Sabra, MD, PhD; Barry K. Wershil, MD; Sharon C. Weston, MS, RD, LDN; Lonnie Zeltzer, MD; and Harland Winter, MD. Evaluation, Diagnosis, and Treatment of Gastrointestinal Disorders in Individuals With Autism Spectrum Disorder: A Consensus Report. Pediatrics 125:S1-18, 2010.Jyonouchi, H. Autism spectrum disorders and allergy: Observation from a pediatric allergy/Immunology Clinic. Expert Review in Immunology. 6:397-411, 2010.Jyonouchi H, Cui C, Geng L, Yin Z, Fitzgerald-Bocarsly P. Age-dependent changes in peripheral blood dendritic cell subsets in normal children and children with antibody deficiency syndrome. Eur J Pediatrics. 169:1233-1239, 2010. Jyonouchi H, Geng L, Streck, D, Toruner, GA. Children with autism spectrum disorders (ASD) who exhibit chronic gastrointestinal (GI) symptoms and markedly fluctuation of behavioral symptoms exhibit distinct innate immune abnormalities and transcrioptional profiles of peripheral blood (PB) monocytes. J Neuroimmunol 15: 73-80, 2011.Jyonouchi H. Geng L, Streck D, Toruner GA. Immunological characterization and transcription profiling of peripheral blood monocytes in children with autism spectrum disorders (ASD) and specific polysaccharide deficiency (SPAD); case study. J Neuroinflammation 2012 Jan 7;9:4.Pedroza LA, Kumar V, Sanborn KB, Mace EM, Niinikoski H, Nadeau K, Vasconcelos Dde M, Perez E, Jyonouchi S, Jyonouchi H, Banerjee PP, Buuskanen O, Condino-Neto A, and Orange JS. Autoimmune regulator (AIRE) contributes to Dectin-1-induced TNF-α production and complexes with caspase recruitment domain-containing protein 9 (CARD9), spleen tyrosine kinase (Syk), and Dectin-1. J Clin Allergy Immunol 129: 464-472, 2012. Jyonouchi H. Non-IgE mediated food allergy – update of Recent Progress in Mucosal Immunity. Allergy and Inflammation – Drug Targets. In press. 2012. (published online)Review articles Kincade PW, Jyonouchi H, Landreth KS, and Lee G: B-lymphocyte precursors in immunodeficient, autoimmune, and anemic mice. Immunol Rev 64:628-645, 1982.Kincade PW, Jyonouchi H, Landreth KS, Engelhart D, Beare NH, Lee G, and Good RA: Factors affecting normal and malignant B lymphocyte precursors. Curr Top Microbial Immunol 113:104-108, 1984.Jyonouchi H and O’Neill Shigeoka A: Delayed-type Hypersensitivity. eMedicine March 9, 2011 (Review) PED/topic558.htm Jyonouchi H and O’Neill Shigeoka A: Hyperimmunoglobulinemia E (Job) Syndrome. eMedicine April 1, 2011 (Review) PED/topic1075.htmAgrawal R and Jyonouchi H : Complement Deficiency eMedicine November 9, 2007 ped/topic447.htmChaptersKincade PW, Jyonouchi H, Landreth KS, and Lee G: Microenvironmental and age influences on development of B lymphocyte lineage cells. In "Progress of Immunology", T Tada and Y Yamamura (eds), Academic Press Japan, Inc. pp 645-655, 1984.Kincade PW and Jyonouchi H: B cell differentiation. In "Iwanami Immunology Series 4". "Evolution and differentiation of the immune system." RA Good (ed), Iwanami Shoten, pp 189-214, 1986.Filipovich AH, Gross T, Jyonouchi H, and Shapiro RS: Immune-mediated hematologic and oncologic disorders, including Epstein-Bar virus infection. In “Immunologic Disorders in infants and children”, ER Stiehm (ed), W. B. Saunders., Philadelpha. pp855-888, 1996.Jyonouchi H: Immunological issues in patients with autism spectrum disorders. (Review) To be included in “Neuropsychiatric Disorders and Infection” (Ed: SH Fatemi), Martin Dunitz & Parthenon Publishing, Taylor & Francis Medical Books. Jan. 2005 pp 187-197.Jyonouchi H, Geng L, Ruby A, and Reddy C: Suboptimal responses to dietary intervention in children with autism spectrum disorders and Non-IgE mediated food allergy. In: ‘Autism Research Advances’ (Editor: L. B. Zhao), pp. 169-184, Nova Science Publishers, Inc. 2007.Jyonouch H Possible impact of innate immunity on autism (Editor: A. Chauhan), Taylor & Francis Group LLC. pp 248-265, 2009Jyonouchi H, Geng L, Kattouf P, Streck D, and Toruner G. Possible impaired oral tolerance in ASD children with food protein induced enterocolitis syndrome (FPIES): Difference in innate and adaptive immune responses in ASD children recovered from FPIES in comparison with non-ASD/FPIES and ASD/non-FPIES children InTech – Book Chapter - published online in August 2011.Jyonouchi H. Food Allergy and Autism Spectrum Disorders. – Book Chapter –“Guidelines in Autism Spectrum Disorders”, in press. Abstracts: (since 1985) Jyonouchi H, Kimmel MD, Good RA: Regulatory dysfunction accounts for hyperactive B lymphocyte formation and later deficiency in NZB mice. Fed Proc. 44(4):978, 1985. [Poster]Jyonouchi H, Voss R, Good RA: IL-1 like activity in murine amniotic fluid. Fed. Proc. 45(4):1000, 1986. [Poster]Jyonouchi H, Voss R, Good RA: Monoclonal antibodies against serum factors of autoimmune NZB mice. Fed Proc. 46:782, 1987. [Poster]Jyonouchi H, Voss R, Good RA: Analysis of the effects of NZB Serum Factor on murine pre-B cell leukemic cell line. FASEB J. 2:A892, 1988. [Poster]Jyonouchi H, Voss R, Good RA: Analysis of effects of humoral factors on CD5 expression by murine 70Z leukemic cell line. FASEB J. 3(4):A1368, 1989. [Poster]Shetty RM, Good RA, Jyonouchi H: Autoimmune neutropenia and erythroid hypoplasia in an infant with anti-HIV antibody who was not infected with HIV virus. Pediatric Res. 25:169A, 1989.Jyonouchi H, Urval K, Nelson R, Klemperer M, Good RA: A case of severe combined immunodeficiency syndrome with apparent normal B cells and the deficiency of post-thymic T lymphocytes. Presented at The American Academy of Allergy and Immunology, 45th Annual Meeting, San Antonio, TX February 24-March 1, 1989, J Allergy and Clin Immunol. 83:288, 1989. [Poster] Jyonouchi H, Voss R, Hill B, Good RA: Common variable immunodeficiency lupus and IL-2 production deficiency. Presented at the annual meeting of the American Academy of Allergy and Immunology, Baltimore, MD, March 23-28, 1990. [Minisymposium]Krishna S, Jyonouchi H, Urval K and Good RA: Studies of serum Fce receptor type II levels in patients with allergy/immunodeficiency disease. Presented at the annual meeting of the American Academy of Allergy and Immunology, Baltimore, MD, March 23-28, 1990. [Poster Symposium]Jyonouchi H, Voss RM, Good RA: Modulation of CD5 expression by a 70Z/3 pre-B leukemic cell line: Role for a labile repressor. Oral presentation at the 1990 Suncoast Biotech Conference, St. Petersburg, FL, March 30, 1990. [Minisymposium]McCann M, Hutto J, Good RA, Jyonouchi H: High-dose intravenous gammaglobulin (IVGG) in treatment of dermatomyositis. Presented before the Ambulatory Pediatric Association, 99th Annual Meeting of the American Pediatric Society, May 1-5, 1989. [Poster Discussion]Di Nicolo R, Hutto J., Jyonouchi H, McCann M, Good RA: Intravenous Gammaglobulin (IVGG) Improves Treatment of Dermatomyositis. 100th Annual Meeting, American Pediatric Society/Society for Pediatric Research, Research 27(2):155A, 1990. Urval K, Sher MR, Jyonouchi H, Day NK, Good RA: A Variant of Common Variable Immunodeficiency (CVI) with Very Low B Cell Numbers and Moderate Hypogammaglobulinemia. American Pediatric Society/Society for Pediatric Research 27(2):163A, 1990.Urval K, Jyonouchi H, Day NK, Good RA: Partial DiGeorge Anomaly - A Review of Immunological Parameters. American Pediatric Society/Society for Pediatric Research 27(2):162A.Jyonouchi H, Voss RM, Good RA: Regulation of CD5 expression by 70Z/3 pre-B leukemic cell line--possible role of a labile repressor. Poster presentation & discussion session, Annual Meeting of the American Association of Immunologists, New Orleans, June 3-7, 1990. FASEB J. 4(7):A2028, 1990. [Poster]Voss RM, Jyonouchi H, Good RA: The presence of 60 kd NZB-serum factor (NZB-SF) in normal strains of mice and its actions in vivo. Poster presentation at the annual meeting of the American Association of Immunologists, New Orleans, June 3-7, 1990. FASEB J. 4(7):A1877, 1990. [Poster]Jyonouchi H, Voss RM, Good RA: Regulation of CD5 expression by 70Z/3 pre-B leukemia cell line -- possible role of labile repressor. Poster presentation at the annual meeting of the Japan Cancer Society, Sapporo, Japan, July 3, 1990. [Poster]Klemperer MR, Jyonouchi H, Nelson RP, Di Nicolo R, Krishna SS, Good RA: Attempted Halploidentical Bone Marrow Transplantation (BMT) in 3 Patients with Lysosomal Storage Diseases (LSD's). 19th Annual ISEH Meeting, Seattle, Washington. Experimental Hematology 18(6):702, 1990. [Poster]Klemperer MR, Jyonouchi H, Nelson RP, Urval K, Sjahli H, Krishna S, Good RA: T-Cell Depleted Partially Matched Bone Marrow Transplantation in a Patient with Omenn's Syndrome, Second Annual Meeting of The American Society of Pediatric Hematology/Oncology, Chicago, Illinois, September 15 through 17, 1990. [Poster]Moore C, Urval K, Day NK, Good RA, Jyonouchi H: B Lineage Cell Populations in a Subset of CVI Patients. 47th Annual Meeting of the American Academy of Allergy Immunology, San Francisco, California, March 1-6, 1991. [Poster Discussion]Sjahli H, Urval K, Good RA, Day NK, Jyonouchi H: Analysis of T and B Lymphocyte Phenotypes in Patients with Partial DiGeorge Syndrome. 47th Annual Meeting of the American Academy of Allergy Immunology, San Francisco, California, March 1-6, 1991. [Poster] Krishna S, Sher M, Jyonouchi H, Prebis J, Perlman S, Good RA: High-Dose Intravenous Gammaglobulin (IVIG) in the Treatment of Systemic Lupus Erythematosus (SLE). 47th Annual Meeting of the American Academy of Allergy Immunology, San Francisco, California, March 1-6, 1991. [Poster]Karlapudi S, Day NK, Good RA, Jyonouchi H: A Case of Primary T Cell Immunodeficiency with Decreased Expression of TCR/CD3 Molecules Associated with Robert's Syndrome. 47th Annual Meeting of the American Academy of Allergy Immunology, San Francisco, California, March 1-6, 1991. [Poster]Tomita Y, Engelman RW, Jyonouchi H, Day NK, and Good RA: Influences of Carotenoids on the Development of Autoimmune Disease in MRL/mpj-lpr/lpr Mice Fed High Calorie Diet. Annual Meeting of AAI, Atlanta, GA, April 21-25, 1991. [Poster]Lopez M, Jyonouchi H, Voss R, and Hill B: Influences of IL-4 and NZB-SF (B cell maturation factor) on spleen lymphocytes obtained from normal and autoimmune-NZB mice. Annual Meeting of AAI, Atlanta, GA, April 21-25, 1991. [Poster]Voss R, Jyonouchi H, and Hill B: The regulatory mechanisms of CD5 expression on murine 70Z/3 pre-B leukemia cell line. Annual Meeting of AAI, Atlanta, GA, April 21-25, 1991. [Poster]Hill B, and Jyonouchi H: Yeast RNA preparations exert immunomodulating actions on murine spleen lymphocytes in vitro. Annual Meeting of AIN, Atlanta, GA, April 21-25, 1991. [Minisymposium]Jyonouchi H, Hill B, and Tomita Y: Influences of immunomodulating nutrients on lymphocyte functions of B6 and autoimmune-prone NZB mice. Annual Meeting of AIN, Atlanta, GA, April 21-25, 1991. [Minisymposium]Klemperer MR, Jyonouchi H, Moore CM, Nelson RP, and Good RA: Bone Marrow Transplantation (BMT) for Lysosomal Storage Diseases (LSDs) Using Partially Matched Donors. Fourth Annual Meeting of The American Society of Pediatric Hematology and Oncology, Chicago, IL, September 12-15, 1991. [Poster]Zhang L and Jyonouchi H: Effects of NZB-serum factors on in vitro Ab and Ig production in NZB and B6 mice. Annual Meeting of FASEB, Anaheim, CA April 5-9, 1992. [Poster]Jyonouchi H, Zhang L, and Tomita Y: RNA/nucleotide and astaxanthin enhance in vitro Ab production to T dependent antigens (TD-Ag) but not to T independent Ag (TI-Ag) or do not further enhance polyclonal B cell activation in NZB mice. Annual Meeting of FASEB, Anaheim, CA, April 5-9, 1992. [Poster]Jyonouchi H and Zhang L: The effects of yeast RNA and nucleotides on in vitro immunoglobulin (Ig) production by human peripheral blood mononuclear cells. Annual Meeting of Society of Pediatric Research, Baltimore MD, May 3-7, 1992 [Poster]Tomita Y, Jyonouchi H, Tanaka K, Himeno, K, and Nomoto K: Augmentation of syngeneic tumor immunity by oral administration of carotenoids. Annual Meeting of Japan Cancer Society, Osaka, Japan, September 25-29, 1992. Japanese Journal of Cancer Research, Abstract:I-67 [Poster]Loechelt BJ, Jyonouchi H, Shapiro RS, Kamat D, and Filipovich AH: Severe immunodeficiency with normotherombocytopenia: A Wiskott-Aldorich (WAS) variant? Annual Meeting of the Clinical Immunology Society, Nov. 13-15, 1992. [Poster Discussion]Filipovich AH, Jyonouchi H, Loechelt B, Kamat D, Dusenberry K, Ramsay N, Kersey J, and Shapiro RS: Non sibling bone marrow transplantation (BMT) for congenital disorders associated with lethal hemophagocytic lymphohistiocytosis. The American Society of Hematology 34th Annual Meeting. Dec. 5-9, 1992. [Poster]Jyonouchi H, Zhang L, Tomita Y, and Gross M.: Immunomodulating actions of carotenoids. Enhancement of Ab production against T-dependent Ag (TD-Ag) in vivo and in vitro. Experimental Biology '93 New Orleans, LO, March 29-April 1, 1993. [Poster]Zhang L, Jyonouchi H, Yokoyama H, and Tomita Y.: Immunomodulating actions of nucleotides on Ab/Ig production by murine spleen lymphocytes in vivo and in vitro. Experimental Biology '93, New Orleans, LO. March 29-April 1, 1993. [Minisymposium]Jyonouchi H, Zhang L, Geogieff MK, and Tomita Y: Immunomodulating actions of nucleotides. Enhancement of Ig production by human cord blood lymphocytes. Annual Meeting of Society of Pediatric Research, Washington, D.C. May 3-6, 1993. [Poster]Jyonouchi H, Zhang L, and Tomita Y: Immunomodulating actions of nucleotides on Ab production by murine lymphocytes: Evidence of modification of Th1 and Th2 responses to TD & TD-Ag. Annual Meeting of American Academy of Immunology and Clinical Immunology Society. Denver, CO. May 21 - May 25, 1993. [Poster]Jyonouchi H, Zhang L, Gross, M, Takenaka H, and Tomita Y: Enhancing actions on specific Ab responses to T-dependent antigens in vivo and in vitro. 10th International Symposium on Carotenoids. Trondheim, Norway. June 20 - June 25, 1993 [Poster]Loechelt BJ, Egeler RM, Filipovich AH, Jyonouchi H, and Shapiro RS: Immunosuppression: An alternative maintenance therapy for familial hemophagocytic lymphohistiocytosis. Histiocyte Society, San Francisco, CA Oct. 1993.Shapiro RS, Loechelt BJ, Jyonouchi H, and Filipovich AH: Unrelated bone marrow transplantation in familial hemophagocytic lymphohistiocytosis. Histiocyte Society, San Francisco, CA, Oct. 1993.Jyonouchi H, Hordinsky M, Bollom, T, Lewis S, Sun S, and Blumenthal M: Alopecia areata and atopic features in pediatric population. Annual Meeting of American Academy of Allergy and Immunology. Anaheim, CA March 4 - March 9, 1994. [Poster Symposium]Hordinsky M, Lewis S, Blumenthal M, and Jyonouchi H: Childhood alopecia areata (AA) and atopy. Annual Meeting of Society For Investigative Dermatology. Baltimore, MA April 27 - April 30, 1994. [Poster]Jyonouchi H, Sun S, and Gross M: The meditation of carotenoid immunomodulating activities by cloned T-helper cells and cytokine mRNA expression. Experimental Biology '94. Anaheim, CA. April 24 - April 27, 1994. [Minisymposium]Zhang L, Sun S, Tomita Y, Hayashi K, and Jyonouchi H: In vivo and in vitro actions of all-trans ?-carotene and ?-carotene stereoisomer mixture from alga Dunaliella bardawil on T-dependent humoral immune responses. Experimental Biology '94. Anaheim, CA. April 24 - April 27, 1994. [Minisymposium].Sun S, Yokoyama H, and Jyonouchi H: Actions of mononucleotide/nucleoside mixture (OGVI) and polynucleotides on in vitro T-dependent humoral immune responses in mice fed a nucleotide-free (NF) diet. Experimental Biology '94. Anaheim, CA. April 24 - April 27, 1994. [Minisymposium]Lochelt BJ, Filipovich AH, Jyonouchi H, and Shapiro RS: Successful interferon-a (IFNa) treatment of fulminant FBV-associated B-cell lymphoproliferative disease (BLPD) following T-cell depleted (T-D) halplo-identical bone marrow transplantation (BMT). The Annual meeting of the Society for Pediatric Research 1994. Seatle, WA. May 1994. [Minisymposium]Jyonouchi H, Sun S, and Hayashi H: Immunomodulating actions of carotenoids: Astaxanthin, a carotenoid without provitamin A activity, can enhance in vitro Ig production by both adult peripheral blood and umbilical cord blood lymphocytes. The Annual meeting of the Society for Pediatric Research. May 1994. Seatle WA Shapiro RS, Loechelt BJ, Jyonouchi H, and Filipovich AH: Unrelated donor bone marrow transplantation in familial hemaphagocytic lymphohistiocytosis. 9th Annual Conference on Clinical Immunology 1994. Anaheim, CA. April 22 - 24, 1994. [Poster] Hordinsky M, Lewis, S, Blumenthal M, and Jyonouchi H: Atopy and childhoodd alopecia areata (AA). 43rd Symposium on The Biology of Skin. August 6-10, 1994. Snowmass Village, Colorado. [Poster]Tristani-Firouzi M, Kamanga-Sollo EIP, Right G, Anderson R, Mathur A, and Jyonouchi, H: Kawasaki Syndrome: massive expansion of T cells and suppression of humoral immune responses in the acute stage. The annual meeting of the Northwest Pediatrics Meeting. Sept. 30, 1994. St. Paul, MN. [Oral Presentation] Tomita Y and Jyonouchi H: In vivo and in vitro effects of ?-carotene and astaxanthin on tumor immunity and humoral immunity in mice. Second International Conference: Antioxidant Vitamins and ?-Carotene in Disease Prevention. October 10-12, 1994, Berlin, Germany. [Poster]Tristani-Firouzi M, Kamanga-Sollo EIP, Sun S, Mathur A, and Jyonouchi, H: TCR V? family repertoire and T-cell functions in Kawasaki syndrome (KS). The annual meeting of the American Academy of Allergy and Immunology. Feb. 24-28, 1995. [Poster]Tristani-Firouzi M, Kamanga-Sollo EIP, Sun S, Mathur A, and Jyonouchi, H: TCR V? family repertoire and T-cell functions in Kawasaki syndrome (KS). The 5th International Congress of Kawasaki Synderome. June, 1995 [Minisymposium]Sun S, Ingbar D, and Jyonouchi H: Effects of antioxidant vitamins on MDCK cells, a canine epithelial cell line, in hyperoxia. The annual meeting of Experimental Biology '95. April, 1995. Atlanta, GA [Minisymposium].Jyonouchi H, Sun S, Tomita Y, and Gross M: Astaxanthin, a carotenoid without vitamin A activity, augments antibody production with T-helper clones in response to suboptimal doses of antigen. The annual meeting of Experimental Biology '95. April, 1995. Atlanta, GA [Minisymposium].Yokoyama H, Sun S, Goodman D, Sato S, and Jyonouchi H: Dietary fatty acid modulatesactions of nucleotides on humoral immunity. The annual meeting of Experimental Biology '95. April, 1995. Atlanta, GA [Minisymposium].Sun S and Jyonouchi H: Oral supplementation of a mononucleotide mixture prepared on the basis of mononucleotides in human breast milk restores impaired humoral immunity in mice fed nucleotide-free (NF) diet. The annual meeting of Society of Pediatric Research '95. May, 1995 San Diego, CA [Poster]Jyonouchi H, Sun S, and Gross M: Carotenoid action on in vitro immunoglobulin (Ig) production by human lymhocytes. The annual meeting of Society of Pediatric Research '95. May, 1995 San Diego, CA [Poster]Jyonouchi H, Sun S, Tomita Y, and Gross: Astaxanthin, a carotenoid without vitamin A activity, augments antibody production with Th clones with suboptimal doses of antigen. The Second Gordon Conference on Carotenoids. Feb. 5-9, 1995. Ventula, CA [Poster]Jyonouchi H, Sun S, and Ingbar DH: Antioxidant vitamin protection against hyperoxic injury of MDCK epithelial cells. The annual meeting of Society of Pediatric Research '95. May, 1995. San Diego, CA [Poster]Jyonouchi H, Sun S, M. Mizokami, and Ingbar DH: Antioxidant vitamin protection against hyperoixc injury in MDCK epithelial cells. The annual meeting of the AAAAI March 1996 [Poster]Jyonouchi H, Sun S, and Gross MD: Carotenoid action on cloned, effector-stage murine T-helper activities. Exp. Biology ‘96. April 1996 [Poster]Mizokami M, Sun S, Ingbar DH, and Jyonouchi H: Confluence and antioxidant vitaminprotection determine the effects of hyperoxia and MDCK epithelial cells. Exp. Biology ‘96. April 1996 [Poster] Jyonouchi H and Sining Sun: Nucleotide action on cloned type 1 and type 2 T-helper cells. ASBMB/ASIP/AAI Joint Meeting April ‘96. [Poster]Jyonouchi H, Sun S, Kajander KC, and Rimell FL: Augmented IFN production by sinus infiltrating cells in a subset of chronic sinusitis patients. AAAAI/AAI/CIS Joint Meeting. April ‘97 [Poster]Sun S, Roche A, Germaine G., Kirmani J, Kajander KC, Rimell FL, and Jyonouchi H: Inflammatory and immune responses by sinus lavage cells and peripheral blood lymphocytes in a rabbit model of sinusitis. AAAAI/AAI/CIS Joint Meeting. Feb., ‘97 [Poster]Jyonouchi H, Sun S, and Abiru T: Dietary nucleotides modulate cytokine production by T cells in reseponse to antigen stimuli. Annual meeting of Exp. Biology April, ‘97 [Minisymposium]Abiru T, Sun S, Inbgar DH, and Jyonouchi H: Antioxidatn vitamin and nucleotide effects on homeostasis of human small airway epithelial cells in normoxia and hyperoxia. Annual meeting of Exp. Biology April, ‘97 [Poster]Sun S, Abiru T, and Jyonouchi, H: Actions of polynucleotides on effector-stage type 1 T-helper cell clones: evidence of augmentation of IFN production through costimulatory molecules. Annual meeting of Exp. Biology April, ‘97 [Poster]Jyonouhi H, Sun S, Chareancholvanich S, and Ingbar DH: Homeostasis of cell death and rpoliferation of human small airway epithelial cells: the effects of hyperoxia and antiboxidant vitamins. Annual meeting of ATS, May, ‘97 [Poster]Jyonouchi H, Sun S, Kennedy CA, Kajander KC, and Rimell FL: IgG Ab Levels in The Sinus Lavage, BAL, and Ear Lavage Solutions in A Rabbit Model of Sinusitis with Bacteroides fragilis. Annual meeting of AAAAI, March, ‘98 [Poster]Sun S, Rimell FL, and Jyonouchi H.: Proinlfammatory and Counter-regulatory Cytokine Production by Sinus Lavage Cells in Patients with Chronic Sinusitis without Nasal Polyposis. Annual meeting of AAAAI, March, ‘98 [Minisymposium]Jyonouchi H, Sun S, and Iijima K. Dietary nucleotides modulate T1/T2 immune responses against ovalbumin in BALB/c mice. Annual meeting of Exp. Biology April, ‘98 [Poster]Iijima K, Sun S, Hecht SS, Wang M, and Jyonouchi H: The effects of Benzo[]pyrene-7,8-diol-9,10-epoxide (BPDE) on human small airway epithelial cells and protective effects of myo-inositol. Annual meeting of Exp. Biology April, ‘98 [Poster]Watanabe Y, Sun S, and Jyonouchi H: The effects of bovine casein degrades on cytokine production by murine T-helper cells. Annual meeting of Exp. Biology April, ‘98 [Poster]Sun S, Gross MD, Iijima K and Jyonouchi H: Anti-tumor activity of astaxanthin on Meth-A tumor cells and its mode of action. Annual meeting of Exp. Biology April, ‘98 [Minisymposium]Choo SY and Jyonouchi H: Immunologic considerations of transfusion in a patient with common variable immunodeficiency and anti-IgA antibody. Annual meeting of the American Association of Blood Banks. Oct. 31 through November 2, 1998. [Oral presentation]Rimell FL, Sun S, and Jyonouchi H: Immune response in chronic sinusitis vs. allergic rhinitis. Annual meeting of Pediatric Otolaryngology and Interamerican Associ. of Ped. Otolaryngol. May, ‘99 [Oral presentation]Sun S, Abiru T, and Jyonouchi H: Pyrimidine but Not Purine Mononucleotides Protect Human Small Airway Epithelial Cells against Injurious Effects of Hyperoxia; Possible Mechanisms of Action. Annual meeting of AAAAI Feb., ‘99 [Poster]Jyonouchi H, Sun S, and Iijima K: Modulation of T1/T2 Responses Against Ovalbumin By Dietary Nucleotides in BALB/c Mice. Annual meeting of AAAAI Feb., ‘99 [Minisymposium]Iijima K, Sun S, Cyong JC, and Jyonouchi H: Juzen-Taiho-To, a Japanese herbal medicine, modulates type 1 and type 2 T cell responses in old BALB/c mice. Annual meeting of Exp. Biology, April, ’99 [Poster]Jyonouchi, H, Sun S., Winship T, and Kuchan MJ: Dietary mononucleotides attenuates skewed type 2 responses in young BALB/c mice against ovalbumin, a representative dietary antigen. Annual meeting of Exp. Biol., Apriol, ’99 [Poster] Jyonouchi H, Kelly AM, Ferrieri P, Rimell RL, and Gollob F A case of necrotizing granulomatous lymphadenitis with [italic]Mycobacterium avium[/italic]; impaired IL-12 dependent IFN production with apparent intact expression of IL-12 receptor (1 and 2 chains) Annual meeting of Society of Pediatric Research, May, ’99 [Poster Discussion]McDowell K, Sun S, Hecht, SS and Jyonouchi H. The Effects of Anti-7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene (BPDE), a Carcinogenic Metabolite of Benzo[a]pyrene (BP) on Activation of Externally Regulated Kinases 1 and 2 (Erk1/Erk2) in Human Small Airway Epithelial (SAE) cells. Annual meeting of AAAAI, March, ’00 [Poster]Jyonouchi H, Sun S, Cornfield, D, and Hecht, SS. The Effects of Anti-7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene (BPDE), a Carcinogenic Metabolite of Benzo[a]pyrene (BP) on Activation of Externally Regulated Kinases 1 and 2 (Erk1/Erk2) in Human Small Airway Epithelial (SAE) cells. Annual meeting of AAAAI, March, ’00 [Poster]Jyonouchi H, Sun S, Winship T, and Kuchan MD. The different effects of dietary supplementation of mononucleotide (MN) and polynucleotide supplementation on antibody (Ab) responses to ovalubmin (OVA), a representative dietary antigen (Ag), in young BALB/c mice. Annual meeting of Exp. Biology, April, ’00 [Minisymposium]S. Sun, D. Cornfield, S. S. Hecht, and Jyonouchi H. Effects of anti-7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene and other carcinogenic polycyclic aromatic hydrocarbon diol epoxides on free cytosolic Ca2+ concentrations of human small airway epithelial cells. Annual meeting of Exp. Biology, April, ’00 [Poster]Jyonouchi H, Sun S, and Rimell, FD. Cytokine production by sinus lavage, bronchial lavage, and peripheral blood mononuclear cells in children with chronic rhinosinusitis. Annual meeting of American Association of Immunologists, May, ’00 [Poster].Rimell FD, Sun S., Le H, and Jyonouchi H. Regulatory cytokine (IL-12, IL-10, and IL-18) production for IFN- by sinus lavage (SL) and peripheral mononuclear (PBMN) cells in children with treatment-resistant chronic rhinosinusitis. Annual meeting of AAAAI held in New Orleans, Louisiana, March, ’01 [Poster]Jyonouchi, H., Sun S, and Le H. Innate and adaptive immune responses in children with regression autism – Evaluation of the effects of environmental factors including vaccination. Annual meeting of AAAAI held in New Orleans, Louisiana, March, ’01 [Poster]Jyonouchi H, Sun S., Winship T, and Kuchan MD. The effects of dietary monoribonucleotides (MNs) on costimulatory molecule expression and memory/effector T cells in response to ovalubmin (OVA) in T2-prone BALB/c mice. Annual meeting of Exp. Biology held in Orlando, FL, April, ’01 [Poster]Jyonouchi H, Sun S, Le H. Proinflammatory/regulatory cytokine production in children with autism spectrum disorders (ASD) Annual meeting of Exp. Biol. ’01 held in Orlando, FL (3/31/01 through 4/4/01)]Jyonouchi H, Sun S., Itokazu, N, and Le HT. Cytokine Production Against Common Dietary Proteins In Patients With Autism Spectrum Disorder And Developmental Regression In Comparison With Patients With Dietary Protein Intolerance. Annual meeting of AAAAI held in New York, NY (3/1/02 through 3/5/02) [Poster]Sun S, Itokazu N, Le, HT, and Jyonouchi H. Innate Immune Responses And Cytokine Production Against Dietary Proteins In Children With Autism Spectrum Disorder (ASD) And Those With Dietary Protein Intolerance (DPI) Annual meeting of AAAAI held in New York, NY (3/1/02 through 3/5/02) [Poster]Jyonouchi H, Sun S, Le H, and Rusche J. CTLA4-Ig down-regulates IFN-? produced by peripheral blood mononuclear cells of autistic and dietary protein intolerant children (DPI). Annual meeting of Exp. Biol. ’02 in New Orleans, Louisiana, (4/21/02 through 4/24/02) [Poster]Sun S, Rimell FL, and Jyonouchi, H. The effects of exogenous IFN-γ in patients with treatment-resistant chronic rhinosinusitis (CRS) Annual meeting of Exp. Biol. ’02 in New Orleans, Louisiana, (4/21/02 through 4/24/02) [Poster]Heimall JR, Jyonouchi H, Oleske J, Bielory L, and Aguila H. Hypersensitivity Pneumonitis linked to Pigeon Exposures: Case Report. Annual meeting of American College of Allergy, Asthma, and Immunology. 2003 (11/8/03 – 11/13/03) [Poster]Du J, Jyonouchi H, Rajakamar A, Zahorodny W, Ming S, Biard S, and Oleske J. Intravenous immunoglobulin treatment in children with immunodeficiency and autism spectrum disorders.Annual meeting of American Allergy, Asthma, and Immunology. 2003 (11/8/03 – 11/13/03) [Poster]Jyonouchi H, Geng L, Ruby A, Zimmerman-Bier, B. Mechanisms of Non-IgE Mediated Adverse Reaction to Common Dietary Proteins (DPs) in Children with Autism Spectrum Disorders (ASD). Annual meeting of American Academy of Asthma, Allergy, and Immunology. 2004 (3/19/04-3/23/04) [Poster]Jyonouchi H, Geng L, Ruby A, Reddy C, Zimmerman-Bier, B. Cytokine Production Profile against Common Dietary Proteins (DPs) in Children with Autism Spectrum Disorders (ASD) on a regular diet: Relationship to Gastrointestinal (GI) Symptoms and Responses to LPS. Annual meeting of Experimental Biology 2004 (4/18/04-4/21/04). [Poster Symposium]Jyonouchi H, Geng L, Ruby A, Zimmerman-Bier, B. The Effects of the Elimination Diet on Cytokine Production Profile against Common Dietary Proteins (DPs) in Children with Autism Spectrum Disorders (ASD). Annual meeting of Experimental Biology 2004 (4/18/04-4/21/04). [Poster Symposium]Lien K, Jyonouchi H, Pletcher B, Aguila H, and Spinnato G. A Case of DiGeorge Syndrome: Development of Sarcoid-like Cutaneous Lesions and Garre’s Osteomyelitis Prior to Diagnosis. Annual meeting of American College of Allergy, Asthma, and Immunology, October, 2004 [Poster]Mosby C, Patel R, Aguila H, McShirly, G, and Jyonouchi, H. Disseminated mycobacterium avium complex infection in a patient with complete interferon gamma receptor deficiency. Annual meeting of American Academy of Asthma, Allergy, and Immunology. 2005 (3/18/05-3/22/05) [Poster]Buddiga P., Pedra-Nobre M., Jyonouchi H., Wolff A., Bielory L. Macrophage activation syndrome associated with posterior reversible encephalopathy syndrome. Annual meeting of American Academy of Asthma, Allergy, and Immunology. 2005 (3/18/05-3/22/05) [Poster]Jyonouchi H, Geng Lee, Ruby A, and Zimmerman-Bier B. Changes in cellular immune reactivity to cow’s milk protein (CMP) following dietary intervention, in children with Autism Spectrum Disorders (ASD) and positive gastrointestinal (GI) symptoms. Annual meeting of Experimental Biology 2005 (4/2/05-4/6/05). [Poster]Jyonouchi H, Geng L, Ruby A, and Zimmerman-Bier B. Aberrant inflammatory responses by peripheral blood derived macrophages and dendritic cells in children with autism spectrum disorders (ASD) and features of immune abnormalities. Annual meeting of Experimental Biology 2005 (4/2/05-4/6/05). [Poster]Ward CM, Geng L, Jyonouchi H. Apparent prenatal sensitization to common dietary proteins (DPs): positive cellular immune reactivity by umbilical cord blood mononuclear cells (UCBCs) to DPs and corresponding clinical features. Annual meeting of American College of Allergy, Asthma, and Immunology. October, 2005 [Poster]Odgen N, Geng, L, Jyonouchi H. Evaluation of cellular immune reactivity to candida antigen in young children with non-allergic food hypersensitivity to cow’s milk. Annual meeting of American Academy of Asthma, Allergy, and Immunology. 2006 (3/3/06-3/7/06) [Poster] Hersh ALB, Geng L, Ruby A, Jyonouchi H. Resolution of PANDAS like symptoms by IVIG in a patient with specific antibody deficiency against polysaccharide antigens. Annual meeting of American Academy of Asthma, Allergy, and Immunology. 2006 (3/3/06-3/7/06) [Poster] Ward C, Geng L, Ruby A, Jyonouchi H. Clinical outcomes and immunoparameters in children with chronic otitis media and rhinosinusitis in response to Pneumovax? vaccine. Annual meeting of American Academy of Asthma, Allergy, and Immunology. 2006 (3/3/06-3/7/06) [Poster] Jyonouchi H, Geng L, Ruby A, Aguila H, Quiraishi H. Decreased production of Th1 and proinflammatory cytokines in children with poor responses to pneumococcal polysaccharide antigens. Annual meeting of American Association of Immunologist. 2006 (5/12/06-5/16/06) [Poster] Jyonouchi H, Geng L, Ruby A, Reddy C. Changes in cellular immune reactivity to cow’s milk protein (CMP) following dietary intervention in young children with non allergic food hypersensitivity (NFH) with or without autism spectrum disorders (ASD). Annual meeting of American Association of Immunologist. 2006 (5/12/06-5/16/06) [Poster] Jyonouchi H, Monteiro I, Geng L, Ruby A. Aberrant responses to TLR (toll-like-receptor) agonists and common luminal antigens (Ags) in patients with inflammatory bowel diseases (IBD); difference between Crohn’s disease (CD) and ulcerative colitis (UC). DDW 2007 (5/19/07-5/24/07) [Poster]Peralejo BM, Aguila H, Geng L, Jyonouchi, H. Mycobacterium fortuitum infection in a child with defective IL-12/23-IFN-γ circuit: dilemmas in diagnosis and treatment. Annual meeting of American Academy of Asthma, Allergy, and Immunology. 2007 (2/23/07-2/27/07) [Poster] Jyonouchi H, Geng Lee, Cushing-Ruby, A, Oh C, Hester JD. Association between TLR4 SNPs (Asp299Gly/Thr399Ile) and non-IgE mediated food allergy (NFA) with or without recurrent otitis media (OM) and chronic rhinosinusitis (CRS). Annual meeting of American Association of Immunologist. 2007 (5/18/07-5/22/07) [Poster]Jyonouchi H, Geng Lee, Cushing-Ruby, A, Quraishi H. Evaluation of atopy and immune functions in children with autism spectrum disorders (ASD): Identification of an ASD subset with distinct clinical and immunological findings. Annual meeting of Experimental Biology 2008 (4/5/07-4/9/08) [Poster]Jyonouchi H, Geng Lee, Cushing-Ruby, Monteiro I. A Th17 vs. Th1 cytokine production against candida and responses to zymosan in patients with chronic airway and gut mucosal inflammation. Annual meeting of Experimental Biology 2008 (4/5/07-4/9/08) [Poster]Kanuga M, Jyonouchi, H, Fitzgerald-Bocarsly P, Cui C, Yin G, Geng L. Atypical Case of Autoinflammatory Disease. Annual meeting of American College of Allergy, Asthma, and Immunology November 2008 [Poster]Nootheti S, Jyonouchi H, Geng L, Cui C, Yin G, Fitzgerald-Bocarsly P. A case of CVID complicated with Stiff Person’s Syndrome – symptomatic relief by rituxmab. Annual meeting of American College of Allergy, Asthma, and Immunology. November 2008 [Poster]Jyonouchi H, Cui C, Geng L, Yin Z, and Fitzgerald-Bocarsly P. Age-dependent changes in peripheral blood dendritic cell subsets in normal children and children with antibody deficiency syndrome. Annual meeting of AAAAI in Washington, DC (3/13/09 – 3/17/09). [Poster]Jyonouchi H, Geng L, Streck D, and Toruner G. Children with autism spectrum disorders (ASD) characterized by frequent viral infection and subsequent loss of cognitive skills differ in mRNA expression of peripheral blood monocytes from other ASD children. Annual meeting of American Academy of Immunologists held in Seattle, WA (5/9-09 – 5-12-09) [Poster]Desai M, Geng L, and Jyonouchi H. A case of severe autoimmune neutropenia: Evidence of Th17 skewed responses. Annual meeting of American College of Allergy, Asthma, and Immunology. November 5-10, 2010. [Poster]. Gendi, S and Jyonouchi H. Food protein induced enterocolitis syndrome complicated with persistent candida enteritis. Annual meeting of American College of Allergy, Asthma, and Immunology. November 5-10, 2009. [Poster]Jyonouchi H, Geng L, Streck D, and Toruner G. A distinct pattern of mRNA expression by monocytes is found in a subset of children with autism spectrum disorders (ASD) who present with recurrent infection, repeated loss of cognitive skills, and persistent gastrointestinal (GI) symptoms. Annual meeting of American Academy of Immunologists held in Baltimore, MA. May 7-10, 2010 [Poster].Kapoor S, Geng L, and Jyonouchi H. Altered responses to agonists of tolle like receptors (TLR) in patients with severe pediatric asthma but not with mild to moderate asthma. Annual meeting of American College of Allergy, Asthma, and Immunology held in Phenix, AZ (11/11/10-11/16-10), [Poster]H. Jyonouchi, L. Geng, S. Kapoor, D. Streck, and G. Toruner. Characterization Of Children With Autism Spectrum Disorders (ASD) Requiring Intravenous Immunoglobulin (IVIG) For Specific Polysaccharide Antibody Deficiency (SPAD)/hypogammaglobulinemia - Distinct Patterns Of Cytokine Production And Gene Expression Profiles. Annual meeting of American Academy of Asthma, Allergy, and Immunology held in San Francisco, CA (3/17/11-3/22/11). [Poster]Kapoor S, Geng L, Feldman A, and Jyonouchi H. Characterization of severe asthma (SA) in children of inner-city of Newark: Altered responses to recall antigens and a panel of agonists of toll like receptors (TLR). Annual meeting of American Academy of Asthma, Allergy, and Immunology held in San Francisco, CA (3/17/11-3/22/11). [Poster]Jyonouch H, Geng L, Streck D, and Toruner G. Children with autism spectrum disorders (ASD) experiencing fluctuating neuropsychiatric symptoms, cognitive skills, and gastrointestinal (GI) symptoms exhibit distinct innate immune abnormalities and transcriptional profiles in peripheral blood (PB) monocytes. Annual meeting of American Association of Immunologist held in San Francisco, CA (5/13/11-5/17/11). [Poster]Feldman A, Rivera R, Geng L, Herbst-Grant M, Kreiswirth B, and Jyonouchi, H. Necrotizing pulmonary infection and rib osteomyelitis in a patient with suboptimal anti-inflammatory response. Annual Meeting of Federation of Clinical Immunology Societies held in Washington, DC (6/23/11-6/26/11) [Poster]Rahimian V, Lee G, and Jyonouchi H. An IL-1 receptor antagonist as a treatment option for treatment-resistant seizures (TRS). Annual Meeting of American College of Allergy and Immunology held in Nov. ’11.Khianey R, Lee G, Aronsky A, and Jyonouchi H. Longitudinal Evaluation of Immune abnormalities in patients with Down syndrome. Annual Meeting of American College of Allergy and Immunology held in Nov. ’11.Rahimian V, Lee G, and Jyonouchi H. : Innate and adaptive immune responses differ in patients with food protein induced enterocolitis syndrome (FPIES) who respond well to the restrictive diet and those who do not. Annual meeting of American Academy of Allergy, Asthma, and Immunology held in Orlando, FL in March ‘12Khianey R, Lee G, Shapiro R, and Jyonouchi H. Immune abnormalities in patients with chronic pain syndrome with unknown etiology. Annual meeting of American Academy of Allergy, Asthma, and Immunology held in Orlando, FL in March ‘12Jyonouchi H, Geng L, Strek D, and Truner AG. Children with autism spectrum disorders (ASD) experiencing fluctuating neuropsychiatric symptoms, cognitive skills, and gastrointestinal (GI) symptoms exhibit distinct innate immune abnormalities and transcriptional profiles in peripheral blood (PB) monocytes . Annual meeting of American Academy of Allergy, Asthma, and Immunology held in Boston, MA in May, ‘12.Invited speaker1. Jyonouchi H: Interleukins - functions and clinical application. Pediatric Ground Round, University of South Florida, Oct. 7, 1988.2. Jyonouchi H: Enhancing actions of carotenoids on specific antibody (Ab) responses to T-dependent antigens in vivo and in vitro In a session of Immunomodulating Actions of Carotenoids Pre-FASEB Carotenoid Symposium, New Orleans March 28, 1993.3. Jyonouchi H: Effects of nucleotides on humoral immune responses - experience both in vivo and in vitro. Pre-FASEB Symposium: "Nucleotides and Nutrition"March 28, 1993.4. Jyonouchi H: Immunomodulating nutrients in breast milkPediatric Ground Round, University of MinnesotaApril 21, 1993 5. Jyonouchi H: Nucleotides as immunomodulating nutrients vs anti-inflammatory agents.Seminars at Otsuka Pharmaceutical Factory, Inc.December 17, 1993.6. Jyonouchi H: Tumor immunity and chemopreventionCME course: University of Minnesota, School of DensitySeptember 30, 1994.7.Jyonouchi H: Dietary fatty acids and nucleotides: their roles in the immune system.Seminars at Otsuka Pharmaceutical Factory, Inc.December 4, 1994.8.Jyonouchi H: Allergic rhinitis and sinus infection CME course: Hennepin County Hospital/University of MinnesotaJanuary 12, 1996.9.Jyonouchi H: Chronic sinus infection in childrenGround round: Ramsey Medical Center (General Pediatrics)February 16, 199610.Jyonouchi H: Inflammatory mediators in chronic sinusitisGround round: University of Minnestoa (Pediatrics)October 16, 199611.Jyonouchi H: The effects of dietary nucleotides on the immune systemInvited lecture: Yamasa Corp. (Choshi, Japan)December 17, 199612.Jyonouchi H: The effects of dietary nucleotides on primary and secondary immune responsesagainst protein neoantigen in rodent models.Invited lecutre: Ross Product Division/Abott LaboratoriesApril 21, 1997Jyonouchi H:The effects of dietary nucleotides on T1 vs. T2 responses against ovalbumin in T2-prone BALB/c mice.Invited lecutre: Meiji Nutrition Research Institute (Odawara, Japan)December 25, 199714.Jyonouchi H: Immunomodulating actions of non-immunogeneic casein degrades.Invited lecutre: Annual Meeting of Gifu Bioreseach Institute (Gifu-City, Japan)Feb. 23, 1998Jyonouchi H: Pathogenesis of RhinosinusitisGround round: University of Minnestoa (Pediatrics)May 13, 1998Jyonouchi H: Adverse Reaction to Food AntigenResident Seminar: University of Minnesota (Ped/Med program)September 1, 1999Jyonouchi H: Proinflammatory and counter-regulatory cytokine production in ASD childrenInvited Seminar at KGNI for basic research (Staten Island, New York)July 16, 2001Jyonouchi H: Aberrant immune responses against dietary proteins in ASD childrenGround Rounds at Univ. of Med. Dent. NJ, Nework, NJJuly 16, 2001Jyonouchi H: Aberrant immune responses in ASD children, Jonty Foundation Research Conference, Minneapolis, MN, Oct. 20, 2001.Jyonouchi H: Think Tank meeting for Autism – Research projects involving Autism Spectrum Disorders. Jonty Foundation Research Conference, Somerset, NJ, March 22-23, 2003Jyonouchi H: Innate immune responses and the linkage to CFSThe 12th Annual CFS Conference – Update on Research and Care, New Jersey CFS Association and Robert Wood Johnson University Hospital April 12, 2003.Jyonouchi H: Chronic rhinosinusitis in children. Grounds Rounds for Surgery department (ENT). UMDNJ-NJMS, April 12, 2006. Jyonouchi H: Autism Immunology Workshop (sponsored by ‘Autism Speaks’ and ‘Cure Autism Now’) held in Pasadena, CA on 1/25/07 – 1/26/07.Jyonouchi H: Autism Kick-off meeting (sponsored by Nutricia North America) held in Gaithersburg, MD on 2/16/07Jyonouchi H: Autism Workshop (Autism Think Tank) sponsored by ARI April 2-3, ’08 held in Cherryhill, NJ.Jyonouchi H: Autism Workshop (Autism Think Tank) sponsored by ARI, Jan 17 ’09 held in Dallas, TX.Jyonouchi H; Autism One 2010 Conference – May 28-30, 2010 (invited speaker for 2 lectures).Jyonouchi H: Food allergy – Oct 20, 2010 (Abotts Nutrition sponsored seminar held in New Bruinwick, NJ.Teaching session:Project Pediatrics – Oct 15, 2003Resident Lecture – Oct 10, 2003 (Primary Immunodeficiency)Fellow’s Lecture – July 22, 2003 (Neuroimmunology)Resident Lecture – Feb 1, 8, 15, and 22, 2005 (Primary Immunodeficiency Lecture series)Ground Rounds – March 10, 2005, Allergy/Immunology Fellowship “Apoptosis and the immune system.’Fellow’s Lecture – Sept. and Oct. 2005 (2 X for A/I fellows and 2X for ID fellows regarding primary immunodeficiency) Ground Rounds – Jan. 26, 2006, Allergy/Immunology Fellowship: Defects in Innate ImmunityClinical Immunology - Aug. 8, 2006, Summer workshop for high-school teachersGround Rounds Oct. 20, 2006 Pediatrics Primary ImmunodeficiencyResidents Lecture Series – Feb. 2008 (3 topics) as noon conferences – anaphylaxis and food allergyResident Lectures Series – June 2009 (3 topics) as noon conferences – allergy/clinical immunology testingGround Rounds, Oct 16, 2009 Pediatrics Molecular mechanisms of primary immunodeficiencyGround Rounds, April 14, 2010 Allergy/Immunology Fellowhip: IVIG treatmentMANUSCRIPT/GRANT REVIEW:J. Nutrition (Ad hoc review board)Cancer and NutritionJ. Immunology J. Applied ChemistryCancer detection and chemopreventionOtolaryngology - Head and Neck Surgery (a member of Editorial Review Panel)Life SciencesNutrition (Ad hoc review board)J. NeuroimmunologyAnn Allergy and ImmunologyPharmacy ReviewBMC GastroenterologyGene and ImmunityJ. Clin. Immunol.J. Ped. Infect. DisActa PediatricaHuman ImmunologyJ PediatrArchivum Immunologiae et Therapiae ExperimentalisExpert Review of GastroenterologyBrain, Behavior, ImmunityPediatric ResearchArchives of General PsychiatryPros OneA member of the review committee for NIH center grant (ZRG1 BNP) “Center of Botany and Dietary Supplements.” - July, 1999A member of the review committee for NIH center grant (ZAT 1C) “Center of Dietary Supplements.” - July 11-12, 2000, May 23-25, 2001A member of the review committee for NCCAM/NIH: Nov, 2000, Feb. 2001A member of Autism Forum “GI autism literature Review” March 2008 – May 2008A member of CDMRP ‘autism program’ review board – Oct. 2009.A member of CDMRP ‘autism program’ review board – Aug. 2010. ................
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