Tibshirani, Robert



Tibshirani, Robert

Active:

Title: New Statistical Methods for Medical Signals and Images

Time Commitments: 15%

Supporting Agency: NIH,

Name and Address of the Funding Agency’s Procuring Contracting/Grants Officer: Grace Peng, 2DEM - Two Democracy Plz, 200, 6707 Democracy Blvd Bethesda, MD 20892 Performance Period: 7/1/03 – 6/30/08

Level of Funding: $1,487,853

Brief Description of the Project’s Goals: To develop methods for analyzing microarray data and medical data that comes in the form of signals or images such as MRI and FMRI scans, and protein mass spec.

List of the Specific Aims: development of statistical methods for signals and images, and testing them on simulated and real data

Title: Flexible and Adaptive Statistical Methods

Time Commitments: 10%

Supporting Agency: NSF

Name and Address of the Funding Agency’s Procuring Contracting/Grants Officer:

Gabor J. Szekely, National Science Foundation, 4201 Wilson Boulevard, Room 1025, Arlington, VA 22230

Performance Period: 8/1/07 – 7/31/10

Level of Funding: $78,460

Brief Description of the Project’s Goals: To develop statistical methods for model selection and combination, and write a textbook on modern statistical learning methods.

List of the Specific Aims: (a) development of statistical methods for model selection and combination, (b) Completion of 2nd ed of text "Element of Statistical Learning"

Title: Proteomic Analysis of Blood Components in Autoimmune Disease

Time Commitments: 5%

Supporting Agency: NIH, NHLBI

Name and Address of the Funding Agency’s Procuring Contracting/Grants Officer:

Performance Period: 9/30/02 – 9/29/09

Level of Funding: $1,320,750

Brief Description of the Project’s Goals: The major goal of this project is to develop proteomic approaches to studying autoimmune disease. The $1,350,763 is the total direct cost for our Proteomic Center.

List of the Specific Aims: development of statistical methods for studying autoimmune disease, specifically RA.

Title: Immunological Signals and the Control of Lymphoma

Time Commitments: 2%

Supporting Agency: Leukemia and Lymphoma Society

Name and Address of the Funding Agency’s Procuring Contracting/Grants Officer:

Performance Period: 10/1/05 – 9/30/10

Level of Funding: $1,042,000

Brief Description of the Project’s Goals: Studies of cell signaling and lymphoma

List of the Specific Aims: development of statistical methods for studying for

studies of cell signaling and lymphoma

Title: Center of Cancer Nanotechnology Excellence Focused on Therapy Response (CCNE-TR)

Time Commitments: 0%

Supporting Agency: NIH

Name and Address of the Funding Agency’s Procuring Contracting/Grants Officer:

Piotr Grodzinski, Building 31 - Claude D Pepper Bldg, 10A52 31 Center Dr

Bethesda, MD 20892

Performance Period: 5/12/06 – 4/30/11

Level of Funding: $2,811,477

Brief Description of the Project’s Goals: Applications of nano-technology to the understanding and treatment of prostate cancer

List of the Specific Aims: develop and assess statistical methodology for nano-technology

Title: Hepatitis C: Studies of Immunity and Pathogenesis

Time Commitments: 5%

Supporting Agency: Rockefeller University

Name and Address of the Funding Agency’s Procuring Contracting/Grants Officer:

Performance Period: 7/1/05 – 6/30/10

Level of Funding: $169,892

Brief Description of the Project’s Goals: Assisting in microarray analysis

List of the Specific Aims: Consult with investigators on issues in microarray analysis

Title: Expression Profiling for Improved Risk Stratification in Normal Karyotype

Time Commitments: 5%

Supporting Agency: Leukemia and Lymphoma Society

Name and Address of the Funding Agency’s Procuring Contracting/Grants Officer:

Performance Period: 10/1/05 – 9/30/08

Level of Funding: $200,000

Brief Description of the Project’s Goals: Gene expression methodology for risk stratification in adult leukemia

List of the Specific Aims: Model expression signatures and correlate the signatures with

risk groups

Title: Clinical and Laboratory Studies of Malignant Lymphomas

Time Commitments: 20%

Supporting Agency: NIH

Name and Address of the Funding Agency’s Procuring Contracting/Grants Officer:

William Merritt, EPN - Exec Plz North, 7014 6130 Executive Blvd

Rockville, MD 20852

Performance Period: 7/17/06 – 3/31/11

Level of Funding: $1,086,564

Brief Description of the Project’s Goals: Studies of cell signaling and lymphoma

List of the Specific Aims:

Title: Tumor Hypoxia: Molecular Studies and Clinical Exploitation

Time Commitments: 0%

Supporting Agency: NIH

Name and Address of the Funding Agency’s Procuring Contracting/Grants Officer:

Helen Stone, EPN - Exec Plz North, 6008, 6130 Executive Blvd Rockville, MD 20852

Performance Period: 2/9/07 – 1/31/12

Level of Funding: $1,005,391

Brief Description of the Project’s Goals: Studying the role of tumor hypoxia for treatment of head and neck cancer

List of the Specific Aims: Consult with investigators on issues in microarray analysis

Title: Massachusetts General Hospital Study

Time Commitments: 5%

Supporting Agency: Massachusetts General Hospital

Name and Address of the Funding Agency’s Procuring Contracting/Grants Officer:

Performance Period: 9/31/01 – 8/31/08

Level of Funding: $636,818

Brief Description of the Project’s Goals: Genomic and proteomic studies of burns and trauma

List of the Specific Aims: develop and test gene expression and protein-based predictor

of recovery in burn and trauma patients

Title: Prognostic Models in Diffuse Large B-Cell Lymphoma

Time Commitments: 5%

Supporting Agency: NIH

Name and Address of the Funding Agency’s Procuring Contracting/Grants Officer:

Performance Period: 9/24/07 – 7/31/11

Level of Funding: $68,792

Brief Description of the Project’s Goals:

List of the Specific Aims: Develop and test pognostic Models in Diffuse Large B-Cell Lymphoma

Pending:

Title: Genome-wide Association in Early-onset Breast Cancer

Time Commitments: 10%

Supporting Agency: Columbia University

Name and Address of the Funding Agency’s Procuring Contracting/Grants Officer:

Performance Period: 7/1/06 – 6/30/11

Level of Funding: $1,009,615

Brief Description of the Project’s Goals: Assist identification of SNP’s that relate to breast cancer

List of the Specific Aims: Model and assess the correlation between SNPs and phenotypes in Early-onset Breast Cancer.

Title: Discovery of Gene Expression Signatures in Cancer Stroma

Time Commitments: 7%

Supporting Agency: Palo Alto Institute for Research Education

Name and Address of the Funding Agency’s Procuring Contracting/Grants Officer:

Performance Period: 7/1/07 – 6/30/12

Level of Funding: $396,916

Brief Description of the Project’s Goals: Statistical analysis of gene expression data in Stroma

List of the Specific Aims: Estimate of gene expression stroma signatures and assess their

prognostic power in breast cancer and other cancer datasets

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