National PBM Drug Monograph
If a dose of 37.5 to 50 mg per day is needed, it should be given in divided doses three times a day. The maximum recommended single dose is 25 mg. If adverse events such as akathisia, restlessness, Parkinsonism, depression, insomnia, anxiety or intolerable sedation occur, titration should be stopped and the dose should be reduced. ................
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