Role of Ser129 phosphorylation of -synuclein in melanoma cells
Importantly, a-syn is predominantly phosphorylated at Ser129 (S129) in Lewy bodies of the PD brain (Fujiwara et al., 2002; Anderson et al., 2006). Thus, a-syn is a central molecule in understanding PD pathobiology, and its phosphorylation at S129 is thought to be involved in PD pathogenesis. a-Syn is not only related to PD, but also to melanoma ... ................
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