GL173-CAD-mRNA-RT-PRC
In January 2018, these codes were moved to Guideline Note 173.81493 Coronary artery disease, mRNA, gene expression profiling by real-time RT-PRC of 23 genes, utilizing whole peripheral blood, algorithm reported as a risk score The information below was retrieved from the November 2015 VbBS meeting materials/minutes. Issue: This is a proprietary algorithm test which can help predict whether a patient's symptoms are due to obstructive coronary artery diseaseStaff recommendation (accepted by subcommittee without discussion): Test is in the development stage, with clinical utility still being determined, so add to SRNC as experimental. Evidence: Rosenberg 2010 validation study conclusion: This test may be useful for assessment of obstructive CAD in non-diabetic pts without known CAD. Phelps 2015 cost effective analysis conclusions: diagnostic testing for oCAD with a novel GES strategy in a 2-threshold model is cost effective by conventional standards. This diagnostic approach is more efficient than usual care of myocardial perfusion imaging alone or a 1-threshold GES strategy in most scenarios. ................
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