Septal Reduction in Hypertrophic Obstructive Cardiomyopathy
5/26/2017
Septal Reduction in Hypertrophic Obstructive Cardiomyopathy
Juan Crestanello, MD Division of Cardiac Surgery The Ohio State University Wexner Medical Center
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Disclosures
Research Grants from:
Medtronic Boston Scientific Abbot Vascular
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1
5/26/2017
HCM Definition
Unexplained LV hypertrophy associated with nondilated ventricular chambers in the absence of another cardiac or systemic disease that itself would be capable of producing the magnitude of hypertrophy evident in a given patient
HCM Definition
0.2 % population 25-30% LVOT obstruction Most common genetic cardiovascular
disease
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Pathology
"Myocardial disarray" "Cellular hypertrophy"
5/26/2017
HCM
Normal
Pathology
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Pathology
5/26/2017
Subaortic Fibrous Patch
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HCM types
5/26/2017
Pathophysiology
LVOT Obstruction Septal Hypertrophy +SAM Dynamic 1/3 patients >30mmHg (surgery 50mmHg)
Mitral Regurgitation Diastolic dysfunction Myocardial ischemia Autonomic dysfunction
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