עדכונים בתעריפון (Word)
Spinal muscular atrophy is caused by loss or mutation of the SMN1 gene and retention of SMN2, leading to low levels of functional SMN. A major function of SMN is assembly of the heptameric Sm ring onto snRNA with SMA tissues having reduced activity which in particular affects the snRNPs critical for splicing of the minor introns. ................
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