National Institute on Drug Abuse. (March 2019). Opioid ...

The rate of unintentional overdoses secondary to opioid use has quadrupled since 1999, accounting for over 29,000 deaths nationally in 2014 (Rudd, Aleshire, Zibbell, & Gladden, 2016). Opioid overdose can be reversed if administration of Naloxone, an opioid antagonist, is given in a timely manner. ................
................