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Weaning Pharmacological Treatment: If two medications are being used, they should be weaned in the following order: Phenobarbital before Morphine, Morphine before Clonidine. Phenobarbital: decrease by 0.5 mg/kg/dose every 48 hours. Given the long half-life, the effects of phenobarbital will gradually wear off over 4 days. Mor. phine: ................
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