Staphylococcal Infection - Bacteremia - IDPodcasts

Staphylococcal Infection Bacteremia

Henry F. Chambers, MD Professor of Medicine, Emeritus University of California San Francisco

Disclosures of Financial Relationships with Relevant Commercial Interests

Moderna ? Stock Merck ? Data Monitoring Committee, Stock Janssen ? Consultant

Outline of the Talk

? Risk factors for poor outcome, complicated bacteremia ? Echocardiography ? Treatment of MSSA bacteremia ? Treatment of MRSA bacteremia ? Oral Therapy ? Duration of Therapy ? Combination therapy

Risk factors for poor outcome, complicated S. aureus bacteremia

Longer durations of Staph. aureus bacteremia (SAB) are associated with higher the mortality

30-Day Mortality (%)

35 30 25 20 15 10

5 0

1

"Breakpoint" (16% increase/day)

2

3

4

5

6

7

Duration of Bacteremia (Days)

Clin Infect Dis. 2020; 70:566-573

8-10

>11

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