Design of Organic Synthesis Part I - UB

Postgraduate Programme in Organic Chemistry 2003?2004

Departament de Qu?mica Org?nica Universitat de Barcelona

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Part I

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by Dr. Pedro Romea

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Design of Organic Synthesis. Part I

4 Credits Wednesdays, from 15 to 17 h, Room 542

Part I

1. Introduction

2. Basic Concepts of Retrosynthetic AnalysOisMe

3. Transform-based Strategies

4. Functional gMrouepO-based Strategies 5. Structural- and TopoOlogycal-baOsed Strategies

6. Stereochemical-based Strategies

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Recommended Texts

Fleming, I. Selected Organic Synthesis. A Guidebook for Organic Chemists. Wiley & Sons. New York, 1973

Serratosa, F. Heurisko. Introducci?n a la sS?ntesis Org?nica. Alhambra. Madrid, 1975

Hanessian, S. Total Synthesis of Natural Products: the "Chiron" Approach.

Pergamon Press. Oxford, 1985

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Corey, E. J.; Cheng, X.-M. The Logic of Chemical Synthesis.

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Wiley & Sons. New York, 1989

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Ho, T.-L. Tactics of Organic Synthesis.

Wiley & Sons. New York, 1994

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Ho, T.-L. Symmetry. A Basis for Synthesis Design.

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Wiley & Sons. New York, 1995

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Lehn, J.-M. Supramolecular Chemistry. Concepts and Perspectives

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VCH. Weinheim, 1995

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Serratosa, F.; Xicart, J. Organic Chemistry in Action. The Design of Organic Synthesis.

Elsevier. Amsterdam, 1996

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Nicolaou, K. C.; Sorensen, E. J. Classics in Total Synthesis. Targets, Strategies, Methods.

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VCH. Weinheim, 1996

O Clayden, J.; Greeves, N.; Warren, S.; Wothers, P. Organic Chemistry. Oxford University Press, 2001 HO OMe Fuhrhop, J.-H.; Li, G. Organic Synthesis. Concepts and Methods. Wiley & VCH. Weinheim, 2003

Nicolaou, K. C.; Snyder, S. A. Classics in Total Synthesis II. More Targets, Strategies, Methods. Wiley & VCH. Weinheim, 2003

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Recommended Texts (II)

Warren, S. Workbook for Organic Synthesis: the Disconnection Approach. Wiley & Sons. New York, 1982

Carda, M.; Rodr?guez, S.; Gonz?lez, F.; Murga, J.; Falomir, E.; Castillo, E. S?ntesis Org?nica. Resoluci?n de problemas por el m?todo de desconexi?n.

Publicaciones Univ. Jaume I. Castell?n, 1996

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Design of Organic Synthesis

Part I

OMe1. Introduction

2. BasicMCeoOncepts of Retrosynthetic Analysis

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3. Transform-based Strategies

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4. OFuncOtional group-based Strategies

5. StructurOal-OaHnd TopologOycal-based Strategies

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6. Stereochemical-bOased Strategies

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