Pain Drug Comparison Chart - Sutter Health
Pain Drug Comparison Chart
Information provided by Sutter Health's MyLifeStages and pain management specialist Karen Pantazis, M.D.
Painkillers are among the most commonly used drugs in the United States. Deciding which to use deserves careful consideration. Use this quick comparison chart to help guide a conversation with your doctor about which
medications are best and safest for you.
Classification Aspirin Family
OVER THE COUNTER
Brand Name
Bayer Bufferin Ascriptin Ecotrin St. Joseph's
Generic Name Aspirin
Best Used For
Minor aches and pains, fever reduction and anti-inflammatory
Acetaminophen
Tylenol Excedrin
Acetaminophen
Pain and fever reduction
COMMON SENSE CONSIDERATIONS
? Talk with your doctor about medication dosage and possible contraindications.
? Never take any drugs when you are pregnant without first consulting your doctor.
? Exercise caution with sensitive groups such as children, the elderly and those with serious health conditions.
Common Side Effects
? GI bleeding ? Increased bleeding ? Ulcers
? Itching/swelling (especially of the face/ tongue/throat)
? Rash ? Dizziness ? Bloody stools ? Stomach bleeding
Warnings
? May contribute to macular degeneration
? Risk of Reyes syndrome in children and teens
? Do not combine with blood thinner medication
? Can cause tinnitus in high doses ? Can cause kidney
problems
? Liver damage possible if you take more than recommended dose or you drink alcohol.
? OTC cough and flu products contain acetaminophen. It can add up quickly. Limit total dose per day to 2000 mg.
NSAIDs
Advil Motrin Aleve
Ibuprofen, naproxen ? also known as non steroidal
Pain, fever reduction and anti-inflammatory
? Heartburn ? Nausea ? Rash ? Dizziness ? Stomach pain
? May increase risk of cardiac events and stroke
? Increases risk of GI bleeding and perforation
? Can cause kidney problems
OVER THE COUNTER [con't]
Classification
Brand Name
Generic Name
Combination
Drugs
Midol Preps
Combinations of acetaminophen, caffeine, naproxen, aspirin
Painkillers combining one or more classes of OTC drugs.
Vanquish
Combination of aspirin, acetominophen and caffeine
Excedrin Migraine
Combinations of acetaminophen, caffeine and ibuprofen
Best Used For
For headaches, bloating, fatigue and menstrual symptoms
For headaches, migraines, headaches, muscle aches, menstrual aches, or other minor aches and pains due to sinusitis, arthritis, or colds
Migraine pain
PRESCRIPTION
Classification
Opioid
Analgesics
NonOpioid
Analgesics
Brand Name
Vicodin Norco Lortab / Lorcet
Oxycodone Percocet
MS ER / Kadian Methadone Dilaudid Opana Duragesic Patch
Generic Name
Hydrocodone and acetaminophen
Oxycodone Oxycodone and acetaminophen Morphine Methadone Hydromorphone Oxymorphone Fentanyl Patch
Best Used For Moderate to Severe Pain
Severe Pain
Neuropathic Pain Medication
Neurontin Ultram Lyrica Cymbalta Topamax Pamelor
Gabapentin Tramadol Pregabalin Duloxetine Topiramate Nortriptylline
Opioid Agonist / Antagonists
Butrans
Bupronorphene Patch
Moderate to Severe Pain
Common Side Effects
? Dizziness ? GI bleeding ? GI upset ? Irritability ? Nervousness
? Irritation of stomach or intestines
? Nervousness ? Nausea ? Taste problems ? Trouble sleeping ? Ulcer from stomach acid
? Dizziness ? GI bleeding ? GI upset ? Irritability ? Nervousness
Warnings
? Consider all warnings for aspirin, acetaminophen and NSAIDs like ibuprofen, since combination drugs may combine one or more classes.
Common Side Effects
? Constipation, nausea, respiratory depression in high doses or when mixed with other meds or alcohol, can lead to death
Warnings
? Do not overtake these medications! Take ONLY as prescribed.
? Can lead to death from respiratory depression if overtaken or mixed with other sedatives, including alcohol.
? Can lead to dependence and tolerance, which are different than addiction.
? Can lead to addiction, especially in high risk individuals
? Dizziness ? Nausea
? Do not stop medication suddenly
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