Answers to Practice Problem Set #5

Answers to Practice Problem Set #5

1. Cephalexin (comon trade name: Keflex) is an antibiotic. The usual pediatric dosage regimen for strep pharyngitis (strep throat) is 25-50mg/kg/day in 2 divided doses. You receive a prescription to fill a 10-day supply of this medication for a 32-pound child with strep throat. The product is available as an oral suspension, 250mg/5ml. Please write the instructions that you will place on the prescription label. (Use a complete sentence, please).

instructions:_Take one teaspoonful twice daily for 10 days.

(25-50mg/kg/day)(14.5kg)(1day/2doses)(5ml/250mg)(1tsp/5ml) = 0.73?1.45 tsp Note that there is no need to go outside the dosing range when you have a perfectly acceptable dose within the recommended dosing range.

2. You are asked to recommend an initial dose of lisinopril, an angiotensin-converting enzyme inhibitor used for blood pressure control that also can slow the progression of renal (kidney) disease. The patient is a 45 year-old, 165-pound, 5'3" female with a serum creatinine of 2.4 mg/dl. Facts and Comparisons gives you the following information:

CrCl (ml/min) >30 10, 30 ................
................

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