AusPAR Attachment 1: Product Information for Oxycodone ...

Oral administration of naloxone to rats from prior to mating to weaning, or from late gestation to weaning, did not affect reproductive or developmental indices up to 800 mg/kg/day (about 90-fold the naloxone dose at the maximal recommended clinical dose of TARGIN modified release tablets, on a body surface area basis). ................
................