SAFETY DATA SHEET Page: 1 of 5 Capsaicin (technical grade ...
๏ปฟ58.1.11
Page 1/8
Safety Data Sheet
acc. to OSHA HCS
Printing date 05/24/2024
*
Revision date 05/24/2024
1 Identification
กค Product identifier
กค Trade name: Capsaicin (technical grade)
กค Synonym N-[(4-hydroxy-3-methoxyphenyl)methyl]-6E-8-methyl-nonenamide
กค Article number: 10010743
กค CAS Number:
404-86-4
กค EC number:
206-969-8
กค Application of the substance / the mixture
This product is for research use - Not for human or veterinary diagnostic or therapeutic use.
กค Details of the supplier of the safety data sheet
กค Manufacturer/Supplier:
Cayman Chemical Co.
1180 E. Ellsworth Rd.
Ann Arbor, MI 48108
USA
กค Information department: Product safety department
กค Emergency telephone number:
During normal opening times: +1 (734) 971-3335
US/CANADA: 800-424-9300
Outside US/CANADA: 703-741-5970
*
2 Hazard(s) identification
กค Classification of the substance or mixture
~
d
GHS05 Corrosion
Eye Damage 1
~
d
H318 Causes serious eye damage.
GHS07
Acute Toxicity - Oral 4 H302 Harmful if swallowed.
Skin Irritation 2
H315 Causes skin irritation.
กค Label elements
กค GHS label elements
The substance is classified and labeled according to the Globally Harmonized System (GHS).
(Contd. on page 2)
US
58.1.11
Page 2/8
Safety Data Sheet
acc. to OSHA HCS
Printing date 05/24/2024
Revision date 05/24/2024
Trade name: Capsaicin (technical grade)
(Contd. from page 1)
กค Hazard pictograms
~d
d
~
GHS05 GHS07
กค Signal word Danger
กค Hazard statements
H302 Harmful if swallowed.
H315 Causes skin irritation.
H318 Causes serious eye damage.
กค Precautionary statements
P264
Wash thoroughly after handling.
P270
Do not eat, drink or smoke when using this product.
P280
Wear protective gloves / eye protection / face protection.
P301+P312
If swallowed: Call a poison center/doctor if you feel unwell.
P302+P352
If on skin: Wash with plenty of water.
P305+P351+P338 If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if
present and easy to do. Continue rinsing.
P310
Immediately call a poison center/doctor.
P321
Specific treatment (see on this label).
P330
Rinse mouth.
P362+P364
Take off contaminated clothing and wash it before reuse.
P332+P313
If skin irritation occurs: Get medical advice/attention.
P501
Dispose of contents/container in accordance with local/regional/national/international
regulations.
กค Classification system:
กค NFPA ratings (scale 0 - 4)
3
1
Health = 3
Fire = 1
Reactivity = 0
0
กค HMIS-ratings (scale 0 - 4)
HEALTH
*3
FIRE
1
REACTIVITY 0
Health = *3
Fire = 1
Reactivity = 0
กค Other hazards
กค Results of PBT and vPvB assessment
กค PBT: Not applicable.
กค vPvB: Not applicable.
*
3 Composition/information on ingredients
กค Chemical characterization: Substances
กค CAS No. Description
404-86-4 Capsaicin (technical grade)
กค Identification number(s)
กค EC number: 206-969-8
US
(Contd. on page 3)
58.1.11
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Safety Data Sheet
acc. to OSHA HCS
Printing date 05/24/2024
Revision date 05/24/2024
Trade name: Capsaicin (technical grade)
(Contd. from page 2)
*
4 First-aid measures
กค Description of first aid measures
กค General information:
Symptoms of poisoning may even occur after several hours; therefore medical observation for at least
48 hours after the accident.
กค After inhalation: In case of unconsciousness place patient stably in side position for transportation.
กค After skin contact: Immediately wash with water and soap and rinse thoroughly.
กค After eye contact: Rinse opened eye for several minutes under running water. Then consult a doctor.
กค After swallowing: Immediately call a doctor.
กค Information for doctor:
กค Most important symptoms and effects, both acute and delayed
No further relevant information available.
กค Indication of any immediate medical attention and special treatment needed
No further relevant information available.
5 Fire-fighting measures
กค Extinguishing media
กค Suitable extinguishing agents:
CO2, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam.
กค Special hazards arising from the substance or mixture No further relevant information available.
กค Advice for firefighters
กค Protective equipment: No special measures required.
*
6 Accidental release measures
กค Personal precautions, protective equipment and emergency procedures
Wear protective equipment. Keep unprotected persons away.
กค Environmental precautions: Do not allow to enter sewers/ surface or ground water.
กค Methods and material for containment and cleaning up:
Use neutralizing agent.
Dispose contaminated material as waste according to section 13.
กค Reference to other sections
See Section 7 for information on safe handling.
See Section 8 for information on personal protection equipment.
See Section 13 for disposal information.
กค Protective Action Criteria for Chemicals
กค PAC-1: Substance is not listed.
กค PAC-2: Substance is not listed.
กค PAC-3: Substance is not listed.
*
7 Handling and storage
กค Handling:
กค Precautions for safe handling Thorough dedusting.
กค Information about protection against explosions and fires: No special measures required.
กค Conditions for safe storage, including any incompatibilities
กค Storage: Store in accordance with information listed on the product insert.
กค Requirements to be met by storerooms and receptacles: No special requirements.
(Contd. on page 4)
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Safety Data Sheet
acc. to OSHA HCS
Printing date 05/24/2024
Revision date 05/24/2024
Trade name: Capsaicin (technical grade)
(Contd. from page 3)
กค Information about storage in one common storage facility: Not required.
กค Further information about storage conditions: Keep receptacle tightly sealed.
กค Specific end use(s) No further relevant information available.
*
8 Exposure controls/personal protection
กค Additional information about design of technical systems: No further data; see section 7.
กค Control parameters
กค Components with limit values that require monitoring at the workplace: Not required.
กค Additional information: The lists that were valid during the creation were used as basis.
กค Exposure controls
กค Personal protective equipment:
กค General protective and hygienic measures:
Keep away from foodstuffs, beverages and feed.
Immediately remove all soiled and contaminated clothing.
Wash hands before breaks and at the end of work.
Avoid contact with the skin.
Avoid contact with the eyes and skin.
กค Breathing equipment: Not required.
กค Protection of hands:
S
_
Protective gloves
The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.
Due to missing tests no recommendation to the glove material can be given for the product/ the
preparation/ the chemical mixture.
Selection of the glove material on consideration of the penetration times, rates of diffusion and the
degradation
กค Material of gloves
The selection of the suitable gloves does not only depend on the material, but also on further marks of
quality and varies from manufacturer to manufacturer.
กค Penetration time of glove material
The exact break through time has to be found out by the manufacturer of the protective gloves and has
to be observed.
กค Eye protection:
R
_
Tightly sealed goggles
9 Physical and chemical properties
กค Information on basic physical and chemical properties
กค General Information
กค Appearance:
Form:
Solid
Color:
Not determined.
กค Odor:
Characteristic
(Contd. on page 5)
US
58.1.11
Page 5/8
Safety Data Sheet
acc. to OSHA HCS
Printing date 05/24/2024
Revision date 05/24/2024
Trade name: Capsaicin (technical grade)
(Contd. from page 4)
กค Structural Formula
กค Molecular Weight
กค Odor threshold:
C18H27NO3
305.4 g/mol
Not determined.
กค pH-value:
Not applicable.
กค Change in condition
Melting point/Melting range:
Boiling point/Boiling range:
Undetermined.
Undetermined.
กค Flash point:
>93 กใC (>199.4 กใF)
กค Flammability (solid, gaseous):
Product is not flammable.
กค Decomposition temperature:
Not determined.
กค Ignition temperature:
Not determined.
กค Danger of explosion:
Product does not present an explosion hazard.
กค Explosion limits:
Lower:
Upper:
Not determined.
Not determined.
กค Vapor pressure:
Not applicable.
กค Density:
กค Relative density
กค Vapor density
กค Evaporation rate
Not determined.
Not determined.
Not applicable.
Not applicable.
กค Solubility in / Miscibility with
Water:
Not determined.
กค Partition coefficient (n-octanol/water): Not determined.
กค Viscosity:
Dynamic:
Kinematic:
SOLUBILITY
กค Other information
*
Not applicable.
Not applicable.
DMF: 50 mg/ml; DMSO: 30 mg/ml; Ethanol: 50 mg/ml; PBS
(pH 7.2): 0.1 mg/ml
No further relevant information available.
10 Stability and reactivity
กค Reactivity No further relevant information available.
กค Chemical stability
กค Thermal decomposition / conditions to be avoided:
No decomposition if used according to specifications.
กค Possibility of hazardous reactions No dangerous reactions known.
กค Conditions to avoid No further relevant information available.
กค Incompatible materials: strong oxidizing agents
กค Hazardous decomposition products: carbon dioxide; carbon monoxide; nitrogen oxides
*
11 Toxicological information
กค RTECS Number RA8530000
(Contd. on page 6)
US
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