Chapter 5 Amino Acids, Peptides and Proteins
The Edman degradation procedure labels and removes only the N-terminal residue from a peptide, leaving all other peptide bonds intact. The peptide is reacted with phenylisothiocyanate, and the N-terminal residue is ultimately removed as a phenylthiohydantoin derivative. ... The major improvement in peptide and protein synthesis is the solid ... ................
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