November 1998 - MARG



June 2017

CURRICULUM VITAE

Cainan H. Foltz, MD

San Diego Digestive Disease Consultants, Inc.

Medical Associates Research Group, Inc.

American Board of Internal Medicine

Board Certified

8008 Frost Street, Suite 200

San Diego, CA 92123

San Diego Digestive Disease Consultants, Inc. Medical Associates Research Group, Inc.

(858) 292-7527 24-hour (858) 277-5678

(858) 292-7804 Fax (858) 277-2317 Fax

E-Mail: cainan.foltz@

|Scripps Clinic – La Jolla, CA |7/2013 - 6/2016 |

|Fellow - Gastroenterology | |

| | |

|University of California – San Diego, CA |7/2010 - 6//2012 |

|Resident – Internal Medicine | |

| | |

|University of California – San Diego, CA |7/2009 - 6/2010 |

|Intern – Internal Medicine | |

| | |

|Stanford University School of Medicine - Stanford, CA |7/2005 - 6/2009 |

|Doctor of Medicine | |

| | |

|Arizona State University - Tempe, AZ |8/2001 - 5/2005 |

|Bachelor of Arts and Bachelor of Science Degrees | |

|-Dual degrees in Honors Chemistry and Psychology | |

|-Graduated summa cum laude | |

EDUCATION:

PROFESSIONAL

EXPERIENCE: San Diego Digestive Disease Consultants, Inc. 2016 – Present

Medical Associates Research Group, Inc. 2016 – Present

San Diego Endoscopy Center 2016 – Present

4033 Third Avenue, San Diego, CA 92103

Geriatrician 7/2012 – 6/2013

Scripps Clinic Medical Group

La Jolla, CA

Medical Director 8/2012 – 6/2013

Cottonwood Canyon Skilled Nursing Facility

El Cajon, CA

Hospice Medical Director 8/2012 – 6/2013

Silverado Hospice

San Diego, CA

LICENSURE/

CERTIFICATION: Medical Board of California

Physician and Surgeon License #A116914

American Board of Internal Medicine

ABIM certified in Internal Medicine 2012

Good Clinical Practice Course – CITI 8/2016

RESEARCH EXPERIENCE:

8/1/2009-current Ambulatory high resolution esophageal manometry with impedance/pH.

• Working with Ravinder Mittal MD on a study in which I successfully combined high resolution esophageal manometry with impedance/pH monitoring in ambulatory patients. This was presented as a poster of distinction at DDW in 2011. Currently, I am using ambulatory high resolution manometry to investigate the pathophysiology of non-cardiac chest pain.

|6/26/2008 |Research Assistant with Lauren Gerson MD |

| |Department of Gastroenterology & Hepatology at Stanford University |

| |Stanford, CA |

• Conducted a study investigating the effects of sedation during implantation of wireless pH probes on subsequent pH scores. This was presented as a poster at Digestive Disease Week in 2009.

|6/01/2006 |Research Assistant with Helen Bronte-Stewart MD |

| |Department of Neurology and Neurological Sciences at Stanford University |

| |Stanford, CA |

• Conducted a study investigating the effects of medication and deep brain stimulation on fine motor control across hands in Parkinson’s subjects.

• Funded by Medical Scholars research fellowship at Stanford University.

|7/01/2003-12/25/2005 |Research Assistant with Cheryl Conrad Ph.D. |

| |Behavioral Neuroscience, Department of Psychology at Arizona State University |

| |Tempe, AZ |

• Conducted an honors thesis research project investigating the mechanism of chronic stress induced spatial memory deficits.

• Investigated the effects of the drug Phenytoin on chronic stress induced morphological changes in the hippocampus.

• Investigated the effects of chronic stress and high fat diet on hippocampal neurons.

• Funded by School of Life Sciences Undergraduate Research fellowship at ASU.

PUBLICATIONS AND PRESENTATIONS:

Zifan A, Ledgerwood M, Foltz C, Mittal R. Pressure Drift Correction in Prolonged Ambulatory Solid-State High-Resolution Manometry. Poster presentation. Digestive Disease Week, Washington DC, 2015

Foltz C, Strum W. Epiphrenic Diverticulum. Images in clinical medicine. New England Journal of Medicine, 371;26. December 25, 2014.

Foltz C, Strum W. Spontaneous Passage of a Colonic Angiolipoma After Colonoscopy With Forceps Biopsy. Clinical Gastroenterology and Hepatology 13(2), September 2014.

Foltz C, Bhargava V and Mittal R. Prolonged Duration Longitudinal Muscle Contraction in Association with “Angina-Like” Non-Cardiac Chest Pain: Recorded by Ambulatory High Resolution Manometry. Poster presentation. Digestive Disease Week, San Diego CA, 2012

Foltz C, Karstens A, Bhargava V and Mittal R. Prolonged (24 hours) Ambulatory High Resolution Manoemetry Combined with Impedance pH Monitoring to Determine Mechanism of Reflux in Normal Subjects. Poster of Distinction. Digestive Disease Week, Chicago IL, 2011.

Foltz C. Prolonged (24 hours) Ambulatory High Resolution Manoemetry Combined with Impedance pH Monitoring to Determine Mechanism of Reflux in Normal Subjects. Oral presentation, UCSD Internal Medicine Annual Research Symposium, San Diego, CA, May 2011.

Foltz C, Gerson LB. Effect of Intravenous Sedation on Bravo pH Monitoring. Poster Presentation, Gastrointest Endosc 2009; 69: AB340-1. Poster Presentation, Digestive Disease Week, Chicago IL, 2009.

Conrad CD, McLaughlin KJ, Harman JS, Foltz C, Wieczorek L, Lightner E, Wright RL. (2007) Chronic glucocorticoids increase hippocampal vulnerability to neurotoxicity under conditions that produce CA3 dendritic retraction but fail to impair spatial recognition memory. Journal of Neuroscience, 27(31):8278-85.

Baran SE, Campbell AM, Kleen JK, Foltz CH, Wright RL, Diamond DM, Conrad CD. (2005) Combination of high fat diet and chronic stress retracts hippocampal dendrites. Neuroreport, 16:39-43.

Foltz C. (2005) What causes chronic stress-induced spatial memory deficits: Long-term or short-term corticosterone elevations? – Honors Thesis submitted to Barrett Honors College at Arizona State University

ACADEMIC HONORS AND AWARDS:

|2007 |Medical Scholars Research Fellowship, Stanford University |

|2005 |Phil Mickelson Award for Excellence in Psychology, Arizona State University |

|2005 |Phi Beta Kappa Honor Society, Arizona State University |

|2004-2005 |School of Life Sciences Undergraduate Research Fellowship, |

| |Arizona State University |

|2003-2005 |Arizona Resident Merit Scholarship, Arizona State University; full tuition |

|2001-2005 |Dean’s Honor List, Arizona State University |

CLINICAL RESEARCH:

1. A Long Term Follow-up Registry for Subjects Who Achieve a Sustained Virologic Response to Treatment in Gilead-Sponsored Trials in Subjects with Chronic Hepatitis C Infection (SVR Registry). Principal Investigator: Michael Bennett, MD; Sub-investigator: Cainan Foltz, MD, Medical Associates Research Group, Inc. Gilead Sciences, Inc. (PRA International).

2. A Long Term Follow-up Registry Study of Subjects Who Did Not Achieve Sustained Virologic Response in Gilead-Sponsored Trials in Subjects with Chronic Hepatitis C Infection (Sequence Registry). Principal Investigator: Michael Bennett, MD; Sub-investigator: Cainan Foltz, MD, Medical Associates Research Group, Inc. Gilead Science, Inc. (PRA International)

3. A Registry for Subjects with Cirrhosis Who Achieve a Sustained Virologic Response Following Treatment With a Sofosbuvir-Based Regimen Without Interferon for Chronic Hepatitis C Infection in Gilead Sponsored Trials. Principal Investigator: Michael Bennett, MD; Sub-investigator: Cainan Foltz, MD, Medical Associates Research Group, Inc. Gilead Sciences, Inc. (Duke Clinical Research Institute).

4. A Phase 3, Double-Blind, Randomized, Long-Term, Placebo-Controlled, Multicenter Study Evaluating the Safety and Efficacy of Obeticholic Acid in Subjects with Nonalcoholic Steatohepatitis. Principal Investigator: Michael Bennett, MD; Sub-investigator: Cainan Foltz, MD, Medical Associates Research Group, Inc. Intercept Pharmaceuticals, Inc.

5. A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Trial of Oral RPC1063 as Induction and Maintenance Therapy for Moderate to Severe Ulcerative Colitis. Principal Investigator: Michael Bennett, MD, Sub-investigator: Cainan Foltz, MD, Medical Associates Research Group, Inc. Receptos, Inc. (Quintiles).

6. A Phase 3, Multicenter, Open-Label Extension Trial of Oral RPC1063 as Therapy for Moderate to Severe Ulcerative Colitis. Principal Investigator: Michael Bennett, MD, Sub-investigator: Cainan Foltz, MD, Medical Associates Research Group, Inc. Receptos, Inc. (Quintiles).

7. A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Investigate the Efficacy and Safety of Mongersen (GED-0301) for the Treatment of Subjects With Active Crohn’s Disease. Principal Investigator: Michael Bennett, MD, Sub-investigator: Cainan Foltz, MD, Medical Associates Research Group, Inc. 2016. Celgene Corporation (Quintiles).

8. A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety, Tolerability, and Efficacy of GS-0976 in Subjects with Nonalcoholic Steatohepatitis. Principal Investigator: Michael Bennett, MD, Sub-investigator: Cainan Foltz, MD, Medical Associates Research Group, Inc. 2016. Gilead Sciences, Inc. (PRAHS).

9. A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety, Tolerability, and Efficacy of GS-9674 in Subjects with Nonalcoholic Steatohepatitis (NASH). Principal Investigator: Michael Bennett, MD, Sub-investigator: Cainan Foltz, MD, Medical Associates Research Group, Inc. 2017. Gilead Sciences, Inc. (PRAHS).

10. A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Selonsertib in Subjects with Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis. Principal Investigator: Michael Bennett, MD, Sub-investigator: Cainan Foltz, MD, Medical Associates Research Group, Inc. 2017. Gilead Sciences, Inc. (PRAHS).

11. A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Selonsertib in Subjects with Compensated Cirrhosis due to Nonalcoholic Steatohepatitis (NASH). Principal Investigator: Michael Bennett, MD, Sub-investigator: Cainan Foltz, MD, Medical Associates Research Group, Inc. 2017. Gilead Sciences, Inc. (PRAHS).

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