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Phosphodiesterase – 5 (PDE5) inhibitors promote corporal smooth muscle relaxation and blood flow and early use of these agents following prostatectomy may reverse or minimise these adverse effects. All four PDE-5 inhibitors (Avanafil, Sildenafil, Tadalafil, Vardenafil) have been used as supportive therapy to rehabilitate erectile function ... ................
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