AusPAR Attachment 1: Product Information for Cialis ...
Sildenafil and tadalafil are phosphodiesterase type 5 (PDE5) inhibitors. A PDE-5 inhibitor works by opening the blood vessels in the lungs to allow blood to flow through more easily. The advent of PDE5 inhibitors for PAH treatment introduced a second class of oral agents in addition to ERAs, but with comparatively fewer toxicity issues. ................
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