Systemic Lupus Erythematosus (SLE)
A positive ANA is seen in 98 to 99% of patients with SLE. The specificity is low as ANA positivity is seen in up to 15% of the population and more so in patients with chronic infections. A positive ds- DNA is highly specific for lupus and higher titres are seen in patients with renal involvement. Anti- Ro and Anti – La antibodies are seen in subacute cutaneous lupus as well as in SLE where ... ................
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