Description of Study



3913505762000 VOLUNTEERS NEEDED FOR A NUTRITION STUDY AT USDA On Health Benefits of KaleThe Beltsville Human Nutrition Research Center, Beltsville, MDis recruiting nonsmoking adults who are 21-75 years old for a nutrition studyIf you meet the above criteria, you may be eligible for this study of how kale affects the body’s metabolism. The study will be 11 weeks long, with 8 weeks of study participation and 3 weeks of break, and will take place March to June 2018. Remuneration for time and inconvenience will be provided for those who are found eligible and complete some or all of the study procedures satisfactorily.To learn more about the study, you may meet with study staff to review the study procedures and consent form and then schedule a screening meeting if you are still interested. Staff meeting times will be Tuesdays, February 6th, 13th, and 20th at 12 noon, Tuesdays, February 6th, 13th, and 20th at 5:00 pm, and Wednesdays February 7th, 14th, and 21st at 7:00 am in USDA Building 307B on Center Road in Beltsville, MD. No appointment is necessary. You must meet with a staff member and sign the consent form to be considered for participation. For more information CALL (301) 504-5454 (messages checked once/day; messages returned within 3 days)EMAIL volunteers@ars. (messages checked twice daily; messages returned within 2 days)Exclusion Criteria – If any of these apply to you, you will not be eligible to participate: Pregnant, lactating, or intending to become pregnant during the study periodUse of oral contraceptivesWomen who have given birth during the previous 12 monthsPresence of kidney disease, liver disease, gout, hyperthyroidism, hypothyroidism, certain cancers, gastrointestinal disease, pancreatic disease, other metabolic diseases, or malabsorption syndromes requiring special dietsHistory of cancer within last 3 yearsKnown allergy or intolerance to Brassica vegetablesHistory of eating disorders or other dietary patterns which are not consistent with the dietary intervention (e.g., vegetarians, very low-fat diets, high-protein diets)Colonoscopy during three weeks prior to start of studyUnwillingness to abstain from probiotics or vitamin, mineral, herbal and glucosinolate/isothiocyanate supplements for two weeks prior to the study and during the studyUse of tobacco productsOccupational or home exposure to organic solvents or passive smokeCrohn’s disease or diverticulitisSuspected or known strictures, fistulas or physiological/mechanical GI obstructionUse of certain medications (prescription or over-the-counter) that may interfere with the study objectivesType 2 diabetes requiring the use of diabetes pills, insulin, or non-insulin shotsFasting glucose greater than or equal to 126 mg/dLUse of blood-thinning medications such as Coumadin (warfarin), Dicumarol, or Miradon (anisinidione)Unable or unwilling to give informed consent or communicate with study staffSelf-report of alcohol or substance abuse within the past 12 months and/or current treatment for these problems (long-term participation in Alcoholics Anonymous is not an exclusion)Other medical, psychiatric, or behavioral factors that in the judgment of the Principal Investigator may interfere with study participation or the ability to follow the intervention protocol ................
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