TEI INDEX AND SPECTRUM OF DIASTOLIC ABNORMALITIES …



TEI INDEX AND SPECTRUM OF DIASTOLIC ABNORMALITIES IN TAKOTSUBO CARDIOMYOPATHY

A. Mathew, M. Kizilbash, D. Bhandare, L. Afonso

Wayne State University, Detroit, MI, USA

Background: Takotsubo Cardiomyopathy (TC) is a syndrome characterized by transient cardiac regional systolic dysfunction. We sought to characterize the Tei Index (TI), a measure of systolic and diastolic performance and spectrum of diastolic dysfunction in TC:

Methods: Echocardiograms on 19 patients with TC were reviewed. The isovolumic contraction (ICT)and relaxation (IRT) and ejection times (ET) were measured. Left ventricular TI calculated as (ICT + IRT) /ET. Left ventricular volumes and ejection fraction (EF) estimated using the Simpson’s Biplane method. Diastolic function was categorized using Doppler transmitral early (E) and late (A) flow velocities, deceleration time, E’ and A’ velocities from the medial mitral annulus. E/E’ratio was considered representative of LV filling pressure. Left atrial volume was indexed to body surface area (LAVI). Bivariate Pearson correlational analysis was performed.

Results: In patients with TC, the mean TI was elevated compared to historical controls (0.81±0.2 vs. 0.37±0.05, p ................
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