PROSTATE CANCER PATIENT GUIDE - Cloudinary

PROSTATE CANCER

PATIENT GUIDE

A comprehensive resource on diagnosis, treatment, side effects, and risk factors for patients and families with a history of prostate cancer.

"Be vigilant, live healthy, and don't give up. This disease can be conquered."

-- FORMER COMBAT MARINE, KOREAN WAR

About this guide

There are no two ways about it: being diagnosed with cancer is hard, and it is life-changing. Despite increasing optimism about treatment, today's cancer landscape can be challenging, as patients have access to an unprecedented amount of information. There are millions of cancer-related webpages, blogs, and videos available at your fingertips. But it's important to acknowledge that this isn't always a helpful thing. A cancer diagnosis can be disorienting, and for many, the overwhelming volume of information available can be more of a burden than an aid.

This third edition of the guide focuses all of the most current and most accurate information available about contemporary prostate cancer research, treatment, and lifestyle factors into one consolidated resource. It is for any man who has been newly diagnosed, who is in treatment, or is concerned about a rising PSA. Beyond that, it's for any loved one or caregiver who wants to cut through the noise and get directly to need-to-know information for prostate cancer patient navigation. Lastly, as we are beginning to recognize the genetic underpinnings of cancer, this guide is for any family member who might want to understand how shared genes affect their own short- and long-term risk factors--and when they should be screened.

We gratefully acknowledge the scholarly expertise and contributions of our editors, who are world leaders in prostate cancer research: Daniel Spratt, MD (Case Western Reserve University); Heather Cheng, MD, PhD (University of Washington, Fred Hutchinson Cancer Research Center); Stacy Loeb, MD, MSc, PhD (hon) (New York University and Manhattan Veterans Affairs); Alicia Morgans, MD, MPH (Northwestern University); Matthew Cooperberg, MD, MPH, (University of California San Francisco); Wassim Abida, MD, PhD (Memorial Sloan Kettering Cancer Center); Arthur Burnett, MD, MBA (Johns Hopkins University); Nima Sharifi, MD (Cleveland Clinic); William Aronson, MD (UCLA); Angelo Baccala Jr., MD, FACS, MBA (Lehigh Valley Health Network); Neal Shore, MD, FACS (Carolina Urologic Research Center); James Schraidt (Us TOO); Andrew Armstrong, MD (Duke University); Bill Curry; Izak Faiena, MD (Columbia University and James J. Peters VA Medical Center); Christopher Sweeney, MBBS (Dana-Farber Cancer Institute, Harvard Medical School); Howard Soule, PhD (Prostate Cancer Foundation); Stuart Holden, MD (Prostate Cancer Foundation); Jonathan Simons, MD (Prostate Cancer Foundation); Andrea Miyahira, PhD (Prostate Cancer Foundation); Julie DiBiase, PhD, MFA (Prostate Cancer Foundation); and Rebecca Campbell, MD, MPH (Prostate Cancer Foundation).

Copyright 2021 by the Prostate Cancer Foundation (PCF). Originally produced in 2017. The Prostate Cancer Foundation is the world's leading philanthropic organization funding and accelerating prostate cancer research. Since 1993, the Prostate Cancer Foundation has funded key research leading to most of the treatments used by doctors today to improve the lives of patients, with the mission that someday, soon, no man will die of this disease.

Subjects depicted are models and are used for illustrative purposes only. Prostate cancer standards of practice change regularly. For the most up-to-date information, please register for updates at updates.

 TABLE OF CONTENTS

ABOUT THIS GUIDE

1

1. ABOUT YOU AND PROSTATE CANCER

7

GENERAL INFORMATION

7

WHAT IS PROSTATE CANCER?

7

SURVIVING PROSTATE CANCER

7

RATES OF DIAGNOSIS

7

RISK FACTORS

9

SYMPTOMS

9

HISTORY & PROGRESS

10

MEDICAL BASICS

11

THE ANATOMY OF THE PROSTATE

12

THE BIOLOGY OF PROSTATE CANCER

12

UNDERSTANDING METASTASIS

13

WHAT IS PSA?

13

THE BIOLOGY OF SEX STEROIDS

14

PRECISION ONCOLOGY

15

2. FOR THE NEWLY DIAGNOSED

17

UNDERSTANDING YOUR DIAGNOSIS

17

DETECTION, DIAGNOSIS AND STAGING

17

MAKING THE DIAGNOSIS VIA BIOPSY

17

STAGING YOUR DISEASE

19

SELECTING YOUR TREATMENT

22

PROSTATE CANCER PATIENT TREATMENT PATHWAYS

24

ASSEMBLING YOUR TEAM

26

DOCTORS AND PRACTITIONERS

26

FAMILY

27

YOUR SUPPORT NETWORK

27

YOU

29

PROCESSING YOUR DIAGNOSIS

29

TEAR-OUT SHEET: QUESTIONS TO TAKE TO YOUR DOCTOR AFTER INITIAL DIAGNOSIS

31

2 TABLE OF CONTENTS

3. TREATMENT OPTIONS FOR LOCALIZED OR LOCALLY ADVANCED PROSTATE CANCER 33

CHOOSING A TREATMENT OPTION

33

RISK GROUPS

33

ACTIVE SURVEILLANCE

35

WHO SHOULD CHOOSE ACTIVE SURVEILLANCE?

36

SURGERY

37

RADIATION

38

EXTERNAL BEAM RADIATION THERAPY (EBRT)

39

BRACHYTHERAPY

40

HORMONE THERAPY WITH RADIATION

40

WORKSHEET: LOCAL OR LOCALLY ADVANCED PROSTATE CANCER

41

WORKSHEET: TAKING CARE OF YOURSELF DURING CANCER

42

EXPERIMENTAL THERAPIES FOR LOCALIZED PROSTATE CANCER

43

CRYOTHERAPY

44

PROTON BEAM RADIOTHERAPY

44

HIGH INTENSITY FOCUSED ULTRASOUND (HIFU)

44

PRIMARY HORMONE THERAPY

45

TREATMENT OPTIONS BY STAGE

46

4. LIVING WITH AND AFTER PROSTATE CANCER

49

IN TREATMENT: WHAT TO EXPECT

49

MENTAL HEALTH

49

MAXIMIZING QUALITY OF LIFE

49

MONITORING FOR RECURRENCE

50

POSSIBLE SIDE EFFECTS

50

URINARY FUNCTION

50

BOWEL FUNCTION

51

FERTILITY

52

SEXUAL FUNCTION

52

PERMANENT UPGRADES TO HEALTHY LIVING

56

DIET

56

EXERCISE

56

LIFESTYLE CHANGES

57

PROSTATE CANCER PATIENT GUIDE 3

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