CHAPTER 40 The Mechanism of Protein Synthesis
in Initiation of Protein Synthesis Larger ribosome: 80S versus 70S. Initiator tRNAi and Met-tRNAi is not formylated; differs from Met-tRNAm. Initiation involves eIF’s, CAP recognition (eIF-4E), and movement to AUG start codon (eIF-2). Circular structure of eukaryotic mRNA thought to facilitate rebinding of ribosomes Important control point. ................
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