QUICK REFERENCE TO PSYCHOTROPIC MEDICATIONS

QUICK REFERENCE TO PSYCHOTROPIC MEDICATIONS?

DEVELOPED BY JOHN PRESTON, PSY.D., ABPP

To the best of our knowledge recommended doses and side effects listed below are accurate. However, this is meant as a general reference only, and should not serve as a guideline for prescribing

of medications. Please check the manufacturer's product information sheet or the P.D.R. for any changes in dosage schedule or contraindications. (Brand names are registered trademarks.)

ANTIDEPRESSANTS

UsualSelective Action On

NAMES

Daily DosageNeurotransmitters2

Generic

Brand

Range

Sedation ACH1

NE

5-HT

DA

imipramine desipramine amitriptyline nortriptyline clomipramine trazodone nefazodone fluoxetine bupropion sertraline paroxetine venlafaxine desvenlafaxine fluvoxamine mirtazapine citalopram escitalopram duloxetine vilazodone atomoxetine vortioxetine levomilnacipran MAO INHIBITORS phenelzine tranylcypromine selegiline

Tofranil Norpramin Elavil Aventyl, Pamelor Anafranil Desyrel, Oleptro Generic Only Prozac4, Sarafem Wellbutrin4 Zoloft Paxil Effexor4 Pristiq Luvox Remeron Celexa Lexapro Cymbalta Viibryd Strattera Brintellix Fetzima

Nardil Parnate Emsam (patch)

150-300 mg 150-300 mg 150-300 mg

75-125 mg 150-250 mg 150-400 mg 100-300 mg

20-80 mg 150-400 mg

50-200 mg 20-50 mg

75-350 mg 50-400 mg 50-300 mg

15-45 mg 10-40 mg

5-20 mg 20-80 mg 10-40 mg 60-120 mg 10-20 mg 40-120 mg

30-90 mg 20-60 mg

6-12 mg

mid

mid

++

+++

0

low

low +++++

0

0

high high

++

++++

0

mid

mid

+++

++

0

high high

0

+++++

0

mid

none

0

++++

0

mid

none

0

+++

0

low

none

0

+++++

0

low

none ++

0

++

low

none

0

+++++

+

low

low

+

+++++

0

low

none +++

+++

+

low

none +++

+++

+

low

low

0

+++++

0

mid

mid

+++

+++

0

low

none

0

+++++

0

low

none

0

+++++

0

low

none +++

+++

0

low

low

0

+++++

0

low

low +++++

0

0

low

none

+

+++++

+

low

none +++

+++

0

low

none +++

+++

+++

low

none +++

+++

+++

low

none +++

+++

+++

1ACH: Anticholinergic Side Effects 2NE: Norepinephrine, 5-HT: Serotonin, DA: Dopamine (0 = no effect, + = minimal effect, +++ = moderate effect, +++++ = high effect) 3Uncertain, but likely effects 4Available in standard formulation and time release (XR, XL or CR). Prozac available in 90mg time released/weekly formulation

BIPOLAR DISORDER MEDICATIONS

NAMES

Daily

Serum1

N AMES

Generic

Brand

Dosage Range Level

Generic Brand Dosage

Daily Range

Serum1 Level

lithium carbonate olanzapine/ fluoxetine carbamazepine

Eskalith, Lithonate 600-2400

Symbyax 6/25-12/50mg4 Tegretol,Equetro 600-1600

0.6-1.5

2 4-10+

divalproex

Depakote

lamotrigine

Lamictal

oxcarbazepine Trileptal

1Lithium levels are expressed in mEq/l, carbamazepine and valproic acid levels express in mcg/ml. 2Serum monitoring may not necessary 3Not yet established 4Available in: 6/25, 6/50, 12/25, and 12/50mg formulations

750-1500 50-100

50-500

(2)

1200-2400

(2)

ANTI-OBSESSIONAL

NAMES

Generic

Brand

Dose Range1

clomipramine Anafranil

150-300 mg

fluoxetine Prozac1

20-80 mg

sertraline

Zoloft1

50-200 mg

paroxetine Paxil1 20-60 mg

fluvoxamine Luvox1

50-300 mg

citalopram Celexa1

10-40 mg

escitalopram Lexapro1

5-30 mg

vilazodone

Viibryd1

10-40 mg

1often higher doses are required to control obsessive-compulsive symptoms than the doses generally used to treat depression.

PSYCHO-STIMULANTS

NAMES

Generic

Brand

Daily Dosage1

methylphenidate methylphenidate methylphenidate methylphenidate methylphenidate methylphenidate dexmethylphenidate dextroamphetamine lisdexamphetamine d- and l-amphetamine modafinil armodafanil

Ritalin

5-50 mg

Concerta2

18-54 mg

Metadate

5-40 mg

Methylin

10-60 mg

Daytrana (patch)

15-30 mg

Quillivant XR (liquid)2 10-60 mg

Focalin

5-40 mg

Dexedrine

5-40 mg

Vyvanse

30-70 mg

Adderall

5-40 mg

Provigil, Sparlon

100-400 mg

Nuvigil

150-250 mg

1Note: Adult Doses. 2Sustained release

? Copyright 2014, John Preston, Psy.D and P.A. Distributors

ANTIPSYCHOTICS

NAMES

Generic

Brand

Dosage Range1 Sedation Ortho2

EPS3

ACH Effects4

LOW POTENCY chlorpromazine thioridazine clozapine quetiapine HIGH POTENCY perphenazine loxapine trifluoperazine fluphenazine thiothixene haloperidol pimozide risperidone paliperidone olanzapine ziprasidone iloperidone asenapine lurasidone aripiprazole

Thorazine Mellaril Clozaril Seroquel

Trilafon Loxitane Stelazine Prolixin5 Navane Haldol5 Orap Risperdal Invega Zyprexa Geodon Fanapt Saphris Latuda Abilify

50-800 mg high 150-800 mg high 300-900 mg high 150-600 mg mid

8-60 mg mid 50-250 mg low

2-40 mg low 3-45 mg low 10-60 mg low 2-40 mg low 1-10 mg low 4-16 mg low 3-12 mg low 5-20 mg mid 60-160 mg low 12-24 mg mid 10-20 mg low 40-80 mg mid 15-30mg low

high + +

high

+

high

0

mid

+/0

++++ +++++ +++++

+

mid ++++

++

mid +++

++

mid ++++

++

mid +++++

++

mid ++++

++

low +++++

+

low +++++

+

mid

+

+

mid

+

+

low

+/0

+

mid

+/0

++

mid

+

++

low

+

+

mid

+

+

low

+

+

Equivalence5

100 mg 100 mg

50 mg 50 mg

10 mg 10 mg

5 mg 2 mg 5 mg 2 mg 1-2 mg 1-2 mg 1-2 mg 1-2 mg 10 mg 1-2 mg 1-2 mg 10 mg 2 mg

1Usual daily oral dosage 2Orthostatic Hypotension Dizziness and falls 3Acute: Parkinson's, dystonias, akathisia. Does not reflect risk for tardive dyskinesia. All neuroleptics may cause tardive dyskinesia, except clozapine. 4Anticholinergic Side Effects. 5Dose required to achieve efficacy of 100 mg chlorpromazine. 6Available in time-release IM format.

ANTI-ANXIETY

Generic

NAMES Brand

Single Dose Dosage Range

BENZODIAZEPINES

diazepam

Valium

2-10 mg

chlordiazepoxide Librium

10-50 mg

clorazepate

Tranxene

3.75-15 mg

clonazepam

Klonopin

0.5-2.0 mg

lorazepam

Ativan

0.5-2.0 mg

alprazolam

Xanax, XR 0.25-2.0 mg

OTHER ANTIANXIETY AGENTS

buspirone

BuSpar

5-20 mg

gabapentin

Neurontin 200-600 mg

hydroxyzine

Atarax, Vistaril 10-50 mg

propranolol

Inderal

10-80 mg

atenolol

Tenormin

25-100 mg

guanfacine

Tenex, Intuniv 0.5-3 mg

clonidine

Catapres, Kapvay 0.1-0.3 mg

prazosin2

Minipress

5-20 mg

pregabalin

Lyrica

25-450 mg

Equivalence1

5 mg 25 mg 10 mg 0.25 mg

1 mg 0.5 mg

1Doses required to achieve efficacy of 5 mg of diazepam 2For treatment of nightmares and day time anxiety

HYPNOTICS

NAMES

Single Dose

Generic

Brand

Dosage Range

temazepam triazolam zolpidem zolpidem zaleplon eszopiclone ramelteon diphenhydramine doxepin

Restoril

15-30 mg

Halcion

0.25-0.5 mg

Ambien

5-10 mg

Intermezzo

1.75 mg

Sonata

5-10 mg

Lunesta 1-3 mg

Rozerem 4-16 mg

Benadryl

25-100 mg

Silenor 3-6 mg

OVER THE COUNTER

Name

Daily Dose

St. John's Wort1, 2

SAM-e3

Omega-34-EPA

Folic acid8

N-acetylcysteine5

Chamomile6

5-HTP7

600-1800 mg 400-1600 mg

1-2 g 500 mcg 1200-2400 mg 200-1500 mg 300-600 mg

1Treats depression and anxiety

5 For trichotillomania

2 May cause significant drug-drug interactions 6Treats anxiety:equivalent:

3Treats depression

one cup of chamomile tea

4Treats depression and bipolar disorder

7 Treats depression

8Note: available as Deplin 1-methylfolate (presctiption) 7.5-15 mg

REFERENCES and RECOMMENDED BOOKS

Handbook of Clinical Psychopharmacology For Therapists (2013) Preston, O'Neal and Talaga

Quick Reference ? Free Downloads Website: PsyD-

Clinical Psychopharmacology Made Ridiculously Simple 8th Edition (2014) Preston and Johnson

Consumer's Guide to Psychiatric Drugs Child and Adolescent

(2009) Preston, O'Neal, Talaga

Psychopharmacology

Made Simple

(2010) Preston, O'Neal, Talaga

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