III. SCHOLARSHIP



Curriculum VitaeMatthew E Witek, MD, MS October 9, 2019I. PRESENT POSITION AND ADDRESSAssistant Clinical ProfessorRadiation Oncology Department of Human OncologyUniversity of Wisconsin-Madison2014-presentAssistant Residency Program DirectorRadiation OncologyUniversity of Wisconsin-Madison2017-presentWORK ADDRESSDepartment of Human OncologyClinical Sciences CenterK4/B100-0600Madison, WI 53792Phone: (608) 263-8500Email: witek@humonc.wisc.eduHOME ADDRESS309 West Johnson Street Apartment 714Madison, WI 53703Cell: (215) 806-4460Email: mattewitek@II. EDUCATION2010-2014Thomas Jefferson University Hospital, Philadelphia, PennsylvaniaResidency in Radiation Oncology2013St. Jude Children’s Research HospitalRotation in Pediatric Radiation Oncology2012Washington University Medical Center, Barnes Jewish HospitalRotation in Gynecologic Radiation Oncology2009-2010Lankenau Hospital, Wynnewood, Pennsylvania, Medical Internship2005-2009Jefferson Medical College, Philadelphia, Pennsylvania, MD 2002-2004Thomas Jefferson University, Philadelphia, Pennsylvania, MS in Clinical Pharmacology1997-2001Villanova University, Villanova, PennsylvaniaBS in Comprehensive ScienceMinor in ChemistryMinor in BusinessCERTIFICATIONS2016The American Board of Radiology: Board Certified Radiation OncologyIII. SCHOLARSHIPMETRICS: h-index 12; i10-index 14GRANT SUPPORTActive 7. Improved Imaging of Head and Neck Cancer Using 0.35T MRI; SPORE Developmental Research Project (Co-Investigator: M. Witek MD); Annual direct cost: $50,0006. Effective Detection and Monitoring of Circulating Tumor Cells (CTCs) from HNSCC Patients; SPORE Developmental Research Program (To be combined with UW17078, #2 in Active.) (Co-Investigator: M. Witek MD); Annual direct cost: $50,0005. Integration of machine learning into a virtualized trial environment for Head and Neck Radiotherapy; Submitted for a Head and Neck SPORE Career Enhancement Program, 2018 (Co-Investigator: M. Witek MD); Annual direct cost: $50,0004. ?Development of a PET/MRI Multi-Modality, Multi-Parametric Framework for the Quantitative Assessment of Treatment Response and Outcome Prediction in Head and Neck Cancer. Pilot Grant from University of Wisconsin Carbone Cancer Center Pilot Grant; Funds requested $49,800 over 2 years. Edward Jackson PhD PI, (Co-Investigator: M. Witek MD) 3. Department of Human Oncology supported trial (Co-Investigator: M. Witek); PET/MRI to Enhance Precision Guidance in Head and Neck Radiation Treatment Planning; Annual direct cost: $40,000; IRB-approval of clinical trial UW16064 on 8/24/20172. Head and Neck SPORE Career Enhancement Program (PI: M. Witek); PET-MRI assessment of early tumor response to predict outcomes of HPV-positive oropharynx cancer patients.; Annual direct cost: $50,000; IRB-approved of clinical trial UW17078 on 10/30/2017; 15/50 accrued.1. Collaborative H&N Cancer MRI/PET Clinical Research Program 2017 Ride Scholarship (PI: M. Witek); $50,000; 2018Under Review or Submitted or Not Funded1. IUCTR-CAP Dissemination & Implementation Research Award: Dissemination and Implementation of a Deintensified Approach to Head and Neck Cancer Radiotherapy across Wisconsin (DAHNCR-W); Annual direct cost $150,000 (Co-PI: M. Witek) – Not fundedPEER-REVIEWED PUBLICATIONS30. Radiation Therapy for Head and Neck Cancer in Scleroderma Patients: A Case Series and Literature Review: Nicholas R Rydzewski MD, MPH, Paul Harari, MD, David Francis, MD, Gregory Hartig MD, Matthew Witek, MD. JAMA Otolaryngol Head Neck Surg 2019. Accepted In-Press29. Emphasize treatment of known disease rather than past footprints. Matthew E. Witek and Paul M. Harari. Invited expert opinion for the Gray Zone case section in the Int J Radiation Oncol Biol Phys. Accepted – In press28. Reducing radiotherapy target volume expansion for patients with HPV-associated oropharyngeal cancer: Adam R. Burr, Paul M. Harari, Huaising C. Ko, Matthew E. Witek. Oral Oncology, Volume 92, May 2019, Pages 52-56 . NCCN Guideline Insights: Head and Neck Cancers, Version 2.2018. Colevas AD, Yom SS, Pfister DG, Spencer S, Adelstein D, Adkins D, Brizel DM, Burtness B, Busse PM, Caudell JJ, Cmelak AJ, Eisele DW, Fenton M, Foote RL, Gilbert J, Gillison ML, Haddad RI, Hicks WL, Hitchcock YJ, Jimeno A, Leizman D, Maghami E, Mell LK, Mittal BB, Pinto HA, Ridge JA, Rocco J, Rodriguez CP, Shah JP, Weber RS, Witek M, Worden F, Zhen W, Burns JL, Darlow SD, JNCCN Journal of the National Comprehensive Cancer Network. 2018 May; 16(5): 479-490. . Results from a Free Oral Cancer Screening Clinic at a Major Academic Health Center: Grace C. Blitzer, Stephen A. Rosenberg, Bethany M. Anderson, Timothy M. McCulloch, Aaron M. Wieland, Gregory K. Hartig, Justine Y. Bruce, Matthew E. Witek, Randall J. Kimple, Paul M. Harari. In Press Int J Radiation Oncol Biol Phys 2018 . Letter to the editor regarding “Survival Outcomes for Patients with T3N0M0 Squamous Cell Carcinoma of the Glottic Larynx” – In Reply; Matthew Witek, Gregory Hartig, Paul Harari; JAMA Otolaryngol Head Neck Surg. 2018 Apr 5 . Impact of HPV-Status on Prognostic Potential of the AJCC Staging System for Larynx Cancer: Stacey M. Davidson, MD, Huasing C. Ko, MD, Paul M. Harari, MD, Aaron M. Wieland, MD, Shuai Chen, PhD, Andrew M. Baschnagel, MD, Randall J. Kimple, MD, PhD, Matthew E. Witek MD. Otolaryngol Head Neck Surg. 2018 Apr 1 . NCCN Guideline Insights: Head and Neck Cancers, Version 2.2017. Adelstein D, Gillison ML, Pfister DG, Spencer S, Adkins D, Brizel DM, Burtness B, Busse PM, Caudell JJ, Cmelak AJ, Colevas AD, Eisele DW, Fenton M, Foote RL, Gilbert J, Haddad RI, Hicks WL Jr, Hitchcock YJ, Jimeno A, Leizman D, Lydiatt WM, Maghami E, Mell LK, Mittal BB, Pinto HA, Ridge JA, Rocco J, Rodriguez CP, Shah JP, Weber RS, Witek M, Worden F, Yom SS, Zhen W, Burns JL, Darlow SD. J Natl Compr Canc Netw. 2017 Jun;15(6):761-770 . Are all head and neck squamous cell carcinomas created equal?; Gray Zone case submission to the International journal of radiation oncology, biology, physics, 2017; Case presenter Matthew Witek, Expert Opinions Jimmy Caudell MD, Sampi Patel, and Randal Kimple, 2017 Int J Radiation Oncol Biol Phys, Vol. 99, No. 5, pp. 1059-1060, 2017 . HPV Impacts Survival of Stage IVC Non-Oropharyngeal HNSCC Cancer Patients. Adam Burr, Paul Harari, Huaising Ko, Shuai Chen, Menggang Yu, Andrew Baschnagel, Randall Kimple, Matthew Witek, Otorhinolaryngology-Head and Neck Surgery, March 7, 2017 . Management and survival outcomes for T3N0M0 squamous cell carcinoma of the glottic larynx. Huaising C. Ko MD, Shuai Chen PhD, Aaron M. Wieland MD, Menggang Yu PhD, Andrew M. Baschnagel MD, Randall Kimple, Paul M. Harari MD, Matthew E. Witek MD, JAMA Otolaryngol Head Neck Surg. 2017 Oct 12 . Clinical Outcomes for Patients Presenting with N3 Head and Neck Squamous Cell Carcinoma: Analysis of the National Cancer Database. Huaising C. Ko, Shuai Chen, Aaron M. Wieland, Menggang Yu, Andrew M. Baschnagel, Gregory K. Hartig, Paul M. Harari, Matthew E. Witek, Head Neck. 2017 Nov;39(11):2159-2170 . Prognostic implications of HPV-status for non-oropharyngeal head and neck squamous cell carcinomas. Huaising C. Ko MD, Ryan Sacotte, Shuai Chen PhD, Aaron M. Wieland MD, Menggang Yu PhD, Andrew Baschnagel MD, Justine Bruce MD, Randall Kimple MD, Timothy M. McCulloch MD, Gregory K. Hartig MD, Paul M. Harari MD, Matthew E. Witek MD, 2017 J Cancer Res Clin Oncol. 2017 Nov;143(11):2341-2350 . Outcomes for patients with head and neck squamous cell carcinoma presenting with N3 nodal disease: Matthew E. Witek, Aaron M. Wieland, Shuai Chen, Tabassum A. Kennedy, Craig R. Hullett, Evan Liang, Gregory K. Hartig, Randy J. Kimple, Paul M. Harari. Cancers of the Head & Neck (2017) 2:8 16. Small cell carcinoma of the head and neck: Analysis of the National Cancer Data Base. Kelli B. Pointer, PhD, Huaising C. Ko, MD, Jeffrey V. Brower MD PhD, Matthew E. Witek MD, Randall J. Kimple MD PhD, Paul M. Harari MD, Andrew M. Baschnagel, MD. Oral Oncology, 2017 Jun; 69:92-98 . Dose escalated radiotherapy is associated with improved survival in patients with stage III non-small cell lung cancer: Analysis of the National Cancer Database: Jeffrey V. Brower MD PhD, Arya Amini MD, Shuai Chen, Craig R. Hullett MD PhD, Randall J. Kimple MD, PhD, Michael Bassetti MD, PhD, Matthew E. Witek MD, Menggang Yu PhD, Andrew M. Baschnagel, MD. Annals of Oncology, 2016 Oct;27(10):1887-94 . Pancreatic cancer planning: complex conformal vs. modulated therapies. Chapman KL, Witek ME, Chen H, Showalter TN, Bar-Ad V, Harrison AS. ME, Harrison A. Med Dosim 206 Jan 29, 2016. . Is Financial Literacy Necessary for Radiation Oncology Residents? Matthew E. Witek HYPERLINK "" , Joshua Siglin, Theresa Malatesta, Adam Snook, Eric Gressen, Shari Rudoler, Voichita Bar-Ad, Scot Fisher. International Journal of Radiation Oncology Biology Physics. 12/2014. . A Novel Cdx2 Isoform Regulates Alternative Splicing. Matthew E. Witek, Adam Snook, Scott A. Waldman, Erik S. Blomain, Michael Magee, Ejeria Lin, Bo Xiang. PLoS ONE. 08/2014. . Dose Reduction to the Scalp with Hippocampal Sparing is Achievable with Intensity Modulated Radiotherapy. Witek M, Chapman K, Vahknenko Y, Siglin J, Harrison Y, Xiao Y, Liu H, Andrews D, Shi W International Journal of Medical Physics, Clinical Engineering and Radiation Oncology 08/2014. . Molecular Markers to Predict Clinical Outcome and Radiation-induced Toxicity in Lung Cancer. Review for Journal of Thoracic Disease. Joshua D. Palmer M.D., Nicholas Zaorsky, M.D., Matthew Witek M.D., Bo Lu M.D.,PhD. Journal of thoracic disease. 04/2014; 6(4):387-398. . Tumor Radiotherapy Creates Therapeutic Vaccine Responses to the Colorectal Cancer Antigen GUCY2C. Matthew E. Witek, Adam E. Snook, Michael S. Magee, Bo Xiang, Scott A. Waldman. International journal of radiation oncology, biology, physics 01/2014; 88(5): 1188–1195. . Optimizing Patient Positioning for Intensity Modulated Radiation Therapy in Hippocampal-Sparing Whole Brain Radiation Therapy. Joshua Siglin, MD, Yelena Vakhnenko, BS, Colin E. Champ, MD, Matthew E. Witek, MD, MS, Cheng Peng, PhD, Amy Harrison, MS, Nicolas Zaorsky, MD, Wenyin Shi, MD, PhD. Practical Radiation Oncology, 1/2014. . Treatment-related Acute Esophagitis For Patients With Locoregionally Advanced Non-Small Cell Lung Cancer Treated With Involved-field Radiotherapy and Concurrent Chemotherapy. Bar-Ad V, Leiby B, Witek M, Xiao Y, Cui Y, Dai Y, Cao J, Axelrod R, Campling B, Both S, Werner-Wasik M. Am J Clin Oncol. 2013 Feb 5. . Fractionated stereotactic radiation therapy improves cranial neuropathies in patients with skull base meningiomas: a retrospective cohort study. Shen X, Andrews DW, Sergott RC, Evans JJ, Curran WJ, Machtay M, Fragoso R, Eldredge H, Champ CE, Witek M, Mishra MV, Dicker AP, Werner-Wasik M. Radiat Oncol. 2012 Dec 28. . CDX2 Mini-Review, The Transcription Factor Encyclopedia, Witek ME, Waldman SA. Genome Biol. 2012;13(3): R24. . Bile acids initiate lineage-addicted gastroesophageal tumorigenesis by suppressing the EGF receptor-AKT axis. Gong L, Debruyne PR, Witek M, Nielsen K, Snook A, Lin JE, Bombonati A, Palazzo J, Schulz S, Waldman SA. Clin Transl Sci. 2009 Aug; 2(4): 286-93. . A validated quantitative assay to detect occult micrometastaess by reverse transcriptase-polymerase chain reaction of guanylyl cyclase C in patients with colorectal cancer. Schulz S, Hyslop T, Haaf J, Bonaccorso C, Nielsen K, Witek ME, Birbe R, Palazzo J, Weinberg D. Waldman SA. Clin Cancer Res. 2006 Aug 1:12(15): 4545-52. . Bile acids induce ectopic expression of intestinal guanylyl cyclase C Through nuclear factor-KappaB and Cdx2 in human esophageal cells. Debruyne PR, Witek M, Gong L, Birbe R, Chervoneva I, Jin T, Domon-Dell, C, Palazzo JP, Freund JN, Li P, Pitari GM, Schulz S, Waldman SA. Gastroenterology. 2006 Apr; 130(4): 1191-206. . The putative tumor suppressor Cdx2 is overexpressed by human colorectal adenocarcinomas. Witek ME, Nielsen K, Walters R, Hyslop T, Palazzo J, Schulz S, Waldman SA. Clin Cancer Res. 2005 Dec 15; 11(24 Pt 1): 8540-56. IN PREPARATION4. Can Elective Neck Radiation Treatment Volumes Be Safely Reduced to Diminish Toxicity Profiles for HPV-Positive Oropharynx Patients? Matthew E. Witek, Neil Woody, Hima B. Musunuru, Huaising C. Ko, Richard Ross, Poonam Yadav, Patrick Hill, Menggang Yu, Shlomo Koyfman, Jimmy J. Caudell, Paul M. Harari3. Opiate Use in Patients Undergoing Adjuvant Therapy for Oral Cavity Cancer Huaising C. Ko, Mandira N. Mehra, Paul M. Harari, Matthew E. Witek2. Locoregional Control and Laryngeal and Hypopharyngeal Cancer Patients Treated with Radiotherapy Using Direct Gross Tumor Volume to Planning Target Volume Expansion. Adam R. Burr, Paul M. Harari, Matthew E. Witek MD1. Patterns of failure for oral cavity squamous cell carcinoma patients receiving surgery and adjuvant therapy. Huaising Ko, Paul Harari, Matthew E. WitekNON-PEER REVIEWED PUBLICATIONS 4. Can a non-bulky, T1-2 supraglottic larynx cancer near the vocal cords be treated like a glottic tumor? the mednet April 24, 2018 . Is ENI necessary for postoperative treatment of clinically N0 adenoid cystic carcinoma of the head and neck? the mednet April 24, 2018 . What is your preferred dose-fractionation regimen when treating high-risk SCC of the skin in elderly and/or frail patients? the mednet March 21, 2017 . Do you offer radiation in the setting of a resected desmoplastic melanoma with negative margins given that several retrospective studies show a local control benefit? the mednet January 3, 2017 BOOK CHAPTERS2. 7th?edition of?Perez & Brady’s Principles and Practice of Radiation Oncology: Hypopharynx (Chapter 49) Matthew E. Witek, Timothy J. Kruser, Henry T. Hoffman, Christopher Kandl, Paul M. Harari 1. Improving the Therapeutic Ratio in Head and Neck Cancer; Combining radiation and chemotherapy to improve the therapeutic ratio (Chapter 3) Huasing C. Ko, Pippa F. Cosper, Matthew E. Witek– In pressSELECTED PRESENTATIONS 26. Digital poster presentation at ASTRO 2019, Chicago, IL: Opiate Use in Patients Undergoing Adjuvant Therapy for Oral Cavity Cancer Huaising C. Ko, Mandira N.Mehra, Paul M. Harari, Matthew E. Witek25. Poster presentation at ASCO 2019, Chicago, IL: Window of Opportunity Trial of Cetuximab in Patients (Pts) with Head and Neck Squamous Cell Carcinoma (HNSCC). Justine Yang Bruce, Gil Edward Harmon, Matthew E. Witek, Gregory K Hartig, Aaron Wieland, Tiffany Glazer, Timothy M McCulloch, Kaitlin Woo, Menggang Yu, Diana Trask, Shari Piaskowski, Paul M. Harari, Seungpyo Hong, Deric Wheeler, Randall J. Kimple24. Poster presentation at AACR-AHNS 2019, Austin Tx: Locoregional Control and Laryngeal and Hypopharyngeal Cancer Patients Treated with Radiotherapy Using Direct Gross Tumor Volume to Planning Target Volume Expansion. Adam R. Burr, Paul M. Harari, Matthew E. Witek MD23. Oral presentation at the American Society for Radiation Oncology, San Antonio 2018: High local control rates of p16-positive squamous cell carcinomas of the oropharynx following intensity modulated radiotherapy without a clinical target volume expansion. Adam Burr, Paul Harari, Randall Kimple, Matthew E. Witek?22. Poster presentation at Multidisciplinary Head and Neck Symposium, Scottsdale, AZ, 2018: Changing Demographics of HPV-Associated Oropharyngeal Squamous Cell Carcinoma J.D. Thompson, A. Wieland, T. Glazer, T.M. McCulloch, P.M. Harari, M.E. Witek, R.J. Kimple, J.Y. Bruce, R. Hu, and G.K. Hartig 21. Oral presentation at the American Radium Society, Orlando FL, 2018: Patterns of failure for oral cavity squamous cell carcinoma patients receiving surgery and adjuvant therapy. Huaising Ko, Paul Harari, Matthew E. Witek20. Poster presentation at Multidisciplinary Head and Neck Symposium, Scottsdale, AZ, 2018: Methadone use during concurrent chemoradiation therapy in patients with head and neck cancer; Justine Bruce, Randy Kimple, Paul M. Harari, Matthew E. Witek, Gil Harmon, Kaitlin Woo, Menggang Yu, Jackie L. Kiltz.19. Poster presentation at Multidisciplinary Head and Neck Symposium, Scottsdale, AZ, 2018: Results from a Free Oral Cancer Screening Clinic at a Major Academic Health Center: Stephen A. Rosenberg, Grace C. Blitzer, Huaising C. Ko, Bethany M. Anderson, Heather Geye, Jackie Kiltz, Annie L. Sugar, Seth H. Dailey, Timothy M. McCulloch, Aaron M. Wieland, Gregory K. Hartig, Justine Y. Bruce, Matthew E. Witek, Randall J. Kimple, Paul M. Harari. 18. Poster presentation at Multidisciplinary Head and Neck Symposium, Scottsdale, AZ, 2018: Discordance in outcomes between current staging and HPV-positive squamous cell carcinomas of the larynx; Stacey Davidson, Huaising Ko, Shuai Chen, Paul Harari, Matthew E. Witek 17. Poster presentation at Multidisciplinary Head and Neck Symposium, Scottsdale, AZ, 2018: Towards reduced elective nodal irradiation volumes in HPV-positive oropharynx cancer patients; Huaising Ko, Hima Musunuma, Paul Harari, Aaron Wieland, Matthew E. Witek 16. Poster presentation at Multidisciplinary Head and Neck Symposium, Scottsdale, AZ, 2018: Human Papillomavirus Is Associated with Improved Overall Survival in Patients with Non-Oropharyngeal Squamous Cell Carcinomas Presenting with Metastatic Disease; Adam R. Burr, Paul M. Harari1, Huaising C. Ko, Shuai Chen, Menggang Yu, Andrew M. Baschnagel, Randall J. Kimple, Matthew E. Witek15. Poster presentation at ESTRO, Vienna, Austria, 2017: Rapid Early Response of Gastroesophageal Junction Tumors During Real-Time MRI Guided Radiotherapy Musunuru H, Rosenberg SA, Bayouth J, Mittauer K, Ritter M, Paliwal BR, Witek M, Baschnagel A, Uboha N, Lubner SJ, LoConte NK,?Harari PM, Bassetti MF. Rapid early response of gastroesophageal junction tumors during real-time MRI-guided radiotherapy.14. Poster presentation at ASTRO, San Diego, CA, 2017, Human Papillomavirus Is Associated with Improved Overall Survival in Patients with Non-Oropharyngeal Squamous Cell Carcinomas Presenting with Metastatic Disease; Adam R. Burr, Paul M. Harari, Huaising C. Ko, Shuai Chen2\, Menggang Yu, Andrew M. Baschnagel, Randall J. Kimple, Matthew E. Witek13. Poster presentation at ASTRO, San Diego, CA, 2017, Can Elective Neck Radiation Treatment Volumes be Safely Reduced to Diminish Toxicity Profiles for Oropharynx Cancer Patients?; Hima Musunuma, Huaising Ko, Paul Harari, Aaron Wieland, Matthew Witek12. Poster presentation at American Radium Society, Colorado Springs, CO, 2017: Management and survival outcomes for lymph node negative T3 squamous cell carcinoma of the glottic larynx; Huaising Ko, Shuai Chen, Aaron Wieland, Menggang, Andrew Baschnagel, Jeffrey Brower, Craig Hullett, Randal Kimple, Timothy McCulloch, Greg Hartig, Paul Harari, and Matthew Witek.11. Oral Presentation at ICHNO (ESTRO), Barcelona, Spain, 2017: Patterns of Care and Outcomes for N3 Head and Neck Squamous Cell Carcinoma: Review of the National Cancer Database; Huaising Ko, Jeffrey Brower, Andrew Baschnagel, Craig Hullett, Shuai Chen, Menggang Yu, Aaron Wieland, Paul Harari, and Matthew Witek. 10. Poster presentation at ICHNO (ESTRO), Barcelona, Spain, 2017: Patterns of Care and Outcomes for N3 Head and Neck Squamous Cell Carcinoma: Review of the National Cancer Database; Huaising Ko, Jeffrey Brower, Andrew Baschnagel, Craig Hullett, Shuai Chen, Menggang Yu, Aaron Wieland, Paul Harari, and Matthew Witek. 9. Poster presentation at ASTRO, Boston, MA, 2016: Patterns of Care and Outcomes for N3 Head and Neck Squamous Cell Carcinoma: Review of the National Cancer Database; Huaising Ko, Jeffrey Brower, Andrew Baschnagel, Craig Hullett, Shuai Chen, Menggang Yu, Aaron Wieland, Paul Harari, and Matthew Witek. 8. Poster presentation at Multidisciplinary Head and Neck Symposium, Scottsdale, AZ, 2016: Clinical Outcomes for Patients with Head and Neck Cancer and N3 Nodal Disease; Matthew E. Witek, Aaron Wieland, Andrzej P. Wojcieszynski, Tabby Kennedy, Gregory Hartig, Paul Harari. 7. Oral presentation at ASTRO, Atlanta, GA, 2013: Single Dose Tumor Irradiation Primes the Immune System for Therapeutic Cancer Vaccination; M.E. Witek, A.E. Snook, M.S. Magee, S.A. Waldman.6. Poster presentation at ASTRO, Miami, FL, 2011: Dose Reduction to the Scalp with Hippocampal Sparing Is Achievable with Intensity Modulated Radiotherapy; Witek ME, Vahknenko Y, Siglin J, Chapman K, Harrison Y, Xiao Y, Liu H, Andrews D, Shi W. 5. Poster presentation at ASTRO, Miami, FL, 2011: Pancreatic Cancer Planning: Conformal vs. Modulated Therapies?; Chapman K, Witek ME, Chen H, Yu Y, Showalter T, Bar-Ad V, Harrison A.4. Poster presentation at the Eastern-Atlantic Research Forum Miami, FL, 2008: A novel splice variant of CDX2 regulates alternative splicing; Matthew E. Witek, MS and Scott A. Waldman MD, PhD. 3. Poster presentation at the Sigma Xi Student Research Competition, Thomas Jefferson University, Philadelphia, PA, 2006: Alternative splicing of CDX2 generates a novel protein with dominant-negative activity; Matthew E. Witek, MS, Stephanie Schulz, PhD, and Scott A. Waldman MD, PhD. 2. Poster presentation at the Sigma Xi Student Research Competition, Thomas Jefferson University, Philadelphia, PA, 2004: The intestine-specific transcription factor Cdx2 is overexpressed in colorectal carcinomas and is a marker of their micrometastases; Matthew E. Witek, MS, Stephanie Schulz, PhD, and Scott A. Waldman MD, PhD. 1. Oral poster presentation at the National Meeting for the American Society of Clinical Pharmacology and Therapeutic, Miami, FL, 2004: The intestine-specific transcription factor Cdx2 is overexpressed in colorectal carcinomas and is a marker of their micrometastases; Matthew E. Witek, MS, Stephanie Schulz, PhD, and Scott A. Waldman MD, PhD.HONORS AND AWARDS20172017 Ride Scholarship; Collaborative H&N Cancer MRI/PET Clinical Research Program2016 Association of Residents in Radiation Oncology Educator of the Year Award, University of Wisconsin-Madison, Madison, Wisconsin2015 Best Paper Award, American Association of Physicists in Medicine Annual Meeting, Anaheim, CA2014Roentgen Resident Research Award, Jefferson Medical College, Department of Radiation Oncology, Philadelphia, PA2012Invitation to the AACR/ASCO Workshop on Methods in Clinical Cancer Research, Vail, CO2008Second Place at the Eastern-Atlantic Research Forum hosted by the University of Miami, Miami, FL2006Best Poster Presentation Medical Division. Sigma Xi Student Research Competition. Thomas Jefferson University, Philadelphia, PA2004Best Poster Presentation Master’s Division. Sigma Xi Student Research Competition. Thomas Jefferson University, Philadelphia, PA2004Top Abstract at the National Meeting for the American Society of Clinical Pharmacology and Therapeutic, Miami, FLNATIONAL CLINICAL TRIAL ACTIVITIES2019Radiation Oncology Co-chair on a submitted NRG phase III trial concept2018-2019Principal Investigator at the University of Wisconsin-Madison for NCI CIRB - NRGHN004 - Randomized Phase II/III Trial of Radiotherapy with Concurrent MED14736 (Durvalumab) vs. Radiotherapy with Concurrent Cetuximab in Patients with Stage III-IVB Head and Neck Cancer with a Contraindication to Cisplatin.2017-2019Principal Investigator at the University of Wisconsin-Madison for EAS3132: Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IV Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery2017-2019Principal Investigator at the University of Wisconsin-Madison for HN003: Cisplatin, Intensity-Modulated Radiation Therapy, and Pembrolizumab in Treating Patients with Stage III-IV Head and Neck Squamous Cell CarcinomaIV. SPECIAL PROCEDURE EXPERIENCE2016-current Head and neck brachytherapy – including oral cavity (lip and oral tongue), oropharynx (base of tongue), and skin cancer V. COOPERATIVE GROUP INVOLVEMENT NATIONAL AND COMMERICAL COMMITTEE ENGAGEMENTS2019-currentSanofi Genzyme Cutaneous Squamous Cell Carcinoma Advisory Board2018-currentCommittee member for program development of the 2020 Multidisciplinary Head and Neck Cancer Symposium2018Co-author (Ellie Maghami) for NCCN Guidelines for Patients: Oral Cancers2018-currentPreviously Untreated Locally Advanced (PULA) task force (NCI)2018-current ASCO Unknown Primary in the Head and Neck Guideline Panel2018-currentMember of the SCOUT (Skin Cancer OUTcomes) Consortium2016-currentNational Comprehensive Cancer Network (NCCN) advisory committee for the head and neck cancer sectionCOOPERATIVE GROUP ACTIVITIES2015-2018ASTRO Education Committee – Head and Neck Section2015-2017Radiotherapy quality assurance for RTOG 1016 2015-2017Radiotherapy quality assurance for RTOG 1216 UNIVERSITY OF WISCONSIN INSTITUTIONAL ACTIVITIES2019-currentTreatment Planning Service Improvement Committee2017-currentClinical Competence Committee2017-2018Raystation Implementation Committee2017-currentDirector of Head & Neck Resident Clinical Research Meeting2016-currentMedical Physics Steering Committee2015-2019Department of Human Oncology Clinical Trials CommitteeADVISORY BOARDS2019-currentSanofi Genzyme Cutaneous Squamous Cell Carcinoma Advisory Board2017-currentThe Stakeholder Advisory Board for the PCORI (Patient Centered Outcome Research Institute) grant entitled, “PRO-ACTIVE: comparing the effectiveness of PROphylACTic swallow InterVENtion for patients receiving radiotherapy for head and neck cancer.REVIEWED ARTICLES2020IJROBP manuscript ROB-D-20-001842019IJROBP manuscript ROB-D-19-0011672019Clinical Otolaryngology manuscript COA-2019-03772019Annals of Surgical Oncology manuscript ASO-2019-06-13872019PLOS ONE manuscript-PONE-D-19-137052019 OncoTargets and Therapy manuscript 2112802019Carcinogenesis manuscript CARCIN-2019-002622019Annals of Surgical Oncology manuscript ASO-2019-03-05152019Head & Neck manuscript HED-19-03692019IJROBP manuscript ROB-D-19-002552018Cancer Management and Research manuscript 2023302018Head & Neck manuscript HED-18-14262018Radiation Oncology manuscript RO-D-18-013322018IJROBP manuscript ROB-D-18-010562018Cancer manuscript CNCR-18-25292018Radiation Oncology manuscript RAON-D-18-004822018Cancer Management and Research manuscript 1802032018Cancer Management and Research manuscript 1789642018Cancer manuscript CNCR-18-18292018JNCCN manuscript JNCCN18-642018Head & Neck manuscript HED-18-07972018Head & Neck manuscript HED-18-01482018Annals of Surgical Oncology manuscript ASO-2018-02-0202018IJROBP manuscript ROB-D-17-011942017IJROBP manuscript ROB-D-16-015152016IJROBP manuscript ROB-D-15-007212016JAMA Oncology manuscript 3532_0_merged_146482016JAMA Oncology manuscript ONC16-1021VI. OUTSIDE EDUCATION ACTIVITY AND INVITED SPEAKING 2020(Future) 2020 Multidisciplinary Head and Neck Cancers Symposium: Expanding Treatment Horizons, Scottsdale Arizona, Moderator: Rare Cancers of the Head and Neck2020(Future) 2020 Multidisciplinary Head and Neck Cancers Symposium: Expanding Treatment Horizons, Scottsdale Arizona, Presenter: Title, Guidelines for Larynx and Hypopharynx Target Delineation 2019 University of Wisconsin Department of Surgery and Oncology CME course, “Understanding HPV and Oral Cancer: From Vaccination to Cancer Treatment Approaches.” Wisconsin Institute for Discovery, Madison, WI: Presentation, “Treatment De-Escalation Efforts: Summary of Clinical Trials.”2019University of Wisconsin Department of Surgery and Oncology CME course, “Understanding HPV and Oral Cancer: From Vaccination to Cancer Treatment Approaches.” Wisconsin Institute for Discovery, Madison, WI: Presentation, “Tumor Board Discussion and Case Presentation.”2019Presentation on the role of Radiology in the treatment of patients with Radiotherapy, invited by Dr. Tabbasum Kennedy, University of Wisconsin, Madison, Wisconsin 2018Keynote Speaker for Accuray Inc. Retreat, “Radiotherapy Benefits,” Middleton, WI2018Live SAM-CME Faculty at the American Society for Radiation Oncology; Title, Elective volumes in common Head and Neck cancers – identifying nodal and non-nodal volumes at risk, San Antonio, TX2018Lurie Cancer Center Multidisciplinary Head & Neck Symposium; Head and Neck Oncology: Where Are We Now and Where Are We Going? Chicago, member (under development)2018CancerStrong mobile application featured doctor (under development)2017-currentSmartBridge contributor2017-currentOnco-anatomy editor for 2017- Q&A contributor for head and neck and non-melanoma skin cancer2018Invited Lecturer for the Medical Oncology Fellows at the University of Wisconsin, Madison, WI, “Radiotherapy in the Management of Cancers.”2018Invited Lecturer for the Otolaryngology Residents at the University of Wisconsin, Madison, WI, “Radiotherapy in Head and Neck Cancers: Seminar.” 2017Speaker for Accuray Inc. Retreat, “Radiotherapy Benefits,” Middleton, WI2017Keynote Speaker at the American College of Veterinary Radiology (ACVR), “Towards Standardization of Tumor Contouring,” Phoenix, AZ2017Keynote Speaker for Accuray Inc. Retreat, “Radiotherapy Benefits,” Middleton, WI2016Carbone Cancer Center Grand Rounds Presenter, “Head and Neck Cancer: Can less be MORE?20167th Annual Midwest Head and Neck Imaging Meeting, University of Wisconsin-Madison. “Radiation Strategies for Head and Neck Cancer,” Madison, WI2015Panel member for open-house in Oncology for the Pre-Medical Chapter of the Wisconsin Medical Society, Madison, WIRESIDENT AND FELLOW MENTORING2017Mentoring PGY-3 University of Wisconsin-Madison radiation oncology resident Cindy Ko, MD on the change of patters of opioid use in patients with head and neck cancer2017Mentoring PGY-3 University of Wisconsin-Madison radiation oncology resident Cindy Ko, MD patters of failure using IMRT for post-operative oral cavity cases. 2017Mentored PGY-5 London Health Sciences Centre radiation oncology resident Stacey Davidson, MD on a novel staging system for HPV-positive laryngeal squamous cell carcinoma. Project in progress. 2017Mentored PGY-3 University of Wisconsin-Madison radiation oncology resident Cindy Ko, MD on a clinical trials submission to AACR Clinical Trial Workshop, Vail, CO 2017Mentoring PGY-2 radiation oncology resident Gregory Manukian, MD from Thomas Jefferson University Hospital on a follow-up project regarding financial literacy of residents. Project in progress. 2017-2019Mentoring PGY-2 University of Wisconsin-Madison radiation oncology resident Adam Burr, MD on a contouring project evaluated target volume expansions, local control, and long-term toxicity. Project in progress.2017Mentoring PGY-2 University of Wisconsin-Madison radiation oncology resident Adam Burr, MD on a NCDB project evaluating the prognostic implication of HPV status in metastatic non-oropharyngeal head and neck squamous cell carcinoma. Project submitted to ASTRO 2017, San Diego, CA2017Mentoring University of Wisconsin-Madison radiation oncology fellow Hima Musunuru, MD on a contouring project evaluating the location of first echelon contralateral lymph node locations for oropharyngeal carcinomas. Project submitted to ASTRO 2017, San Diego, CA.2016Mentoring PGY-3 University of Wisconsin-Madison radiation oncology resident Cindy Ko, MD on NCDB project evaluating the impact of treatment on outcomes of T3N0M0 glottic squamous cell carcinomas. Poster accepted for presentation at ARS. Manuscript submitted for publication.2016Mentored PGY-3 University of Wisconsin-Madison radiation oncology resident Cindy Ko, MD on NCDB project evaluating the impact of HPV-status on non-oropharygneal head and neck squamous cell carcinomas. Manuscript submitted for publication.2016Mentored PGY-3 University of Wisconsin-Madison radiation oncology resident Cindy Ko, MD on NCDB project evaluating the impact of N3 nodal disease on head and neck squamous cell carcinomas resulting in two poster presentations (ASTRO and ARS) and oral presentation (ESTRO-ICHNO). Manuscript submitted for publication.2016Mentoring PGY-2 University of Wisconsin-Madison radiation oncology resident Adam Burr, MD on a NCDB evaluating the prognostic implication of HPV-positive status for metastatic non-oropharyngeal head and neck squamous cell carcinoma. Project is in progress.TEACHING LECTURES2018Performed lecture on oral cavity carcinoma to the University of Wisconsin – Madison radiation oncology residents and faculty.2018Performed lecture on laryngeal carcinoma to the University of Wisconsin – Madison radiation oncology residents and faculty.2017Performed lecture on laryngeal carcinoma to the University of Wisconsin – Madison radiation oncology residents and faculty.2017Performed lecture on nasopharyngeal carcinoma to the University of Wisconsin – Madison radiation oncology residents and faculty.2017Performed lecture on skin cancer to the University of Wisconsin – Madison radiation oncology residents and faculty.2016Performed lecture on laryngeal carcinoma to the University of Wisconsin – Madison radiation oncology residents and faculty.2016Performed lecture on nasopharyngeal carcinoma to the University of Wisconsin – Madison radiation oncology residents and faculty.2015Performed lecture on CNS lymphoma to the University of Wisconsin – Madison radiation oncology residents and faculty.2015Performed lecture on Hodgkin’s lymphoma to the University of Wisconsin – Madison radiation oncology residents and faculty.2015Performed lecture on laryngeal carcinoma to the University of Wisconsin – Madison radiation oncology residents and faculty.2015Performed lecture on nasopharyngeal carcinoma to the University of Wisconsin – Madison radiation oncology residents and faculty.2013Performed lectures on clinical radiation oncology to dosimetry and radiation therapy students at Gwenedd Mercy College.2010-2014Performed annual lectures on clinical radiation oncology to dosimetry and radiation therapy students at Thomas Jefferson University.PROFESSIONAL AFFLIATIONS2017-currentEuropean Society of Radiation Oncology (ESTRO)2015-currentRadiological Society of North America (RSNA)2015-current NRG Oncology 2010-currentAmerican Society of Radiation Oncology (ASTRO)2002-2004American Society of Clinical Pharmacology and Therapeutics (ASCPT)2002-2004Sigma Xi Research SocietyVII. SERVICECOMMUNITY SERVICE2019Performed television advertisement for Free Oral Cancer Screening Program for Spectrum news channel, Madison, Wisconsin.2019Volunteered in a Free Oral Cancer Screening Program at University of Wisconsin, Madison, Wisconsin.2018Volunteered in a Free Oral Cancer Screening Program at University of Wisconsin, Madison, Wisconsin.2017Volunteered in a Free Oral Cancer Screening Program at University of Wisconsin, Madison, Wisconsin.2017Participated in The Ride, A Bicycle Benefit for Cancer Research, sponsored by the University of Wisconsin Department of Human Oncology, Sun Prairie, WI, September 17, 2017.2016Volunteered in a Free Oral Cancer Screening Program at University of Wisconsin, Madison, Wisconsin.2015Performed television advertisement for Free Oral Cancer Screening Program for WKOW news channel, Madison, Wisconsin.2015Volunteered in a Free Oral Cancer Screening Program at University of Wisconsin, Madison, Wisconsin.2014Participated in the Haunted Hustle 5K for Cancer Awareness, Madison, Wisconsin raising $5,700 for patient support and research efforts. ................
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