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“STUDY OF CLINICAL AND IMAGING PROFILE IN THYROTOXICOSIS”

BY

DR. UMAR NAZIR KABLI

SYNOPSIS FOR REGISTRATION OF SUBJECT FOR DISSERTATION

UNDER GUIDANCE OF

GROUP CAPTAIN A.K.DASH

MD (GEN MED), DNB (MEDICINE), DRM (NUCL MED), MNAMS, SR ADV MEDICINE

HOD, DEPARTMENT OF NUCLEAR MEDICINE

COMMAND HOSPITAL AIR FORCE,BANGALORE

TO

RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES

BENGALURU, KARNATAKA

IN PARTIAL FULLFILLMENT OF REGULATIONS FOR AWARD OF

MASTER DEGREE IN MEDICINE

DEPARTMENT OF MEDICINE,

COMMAND HOSPITAL AIR FORCE, BENGALURU-560007

RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES, BENGALURU, KARNATAKA.

ANNEXURE – II

PROFORMA FOR REGISTRATION OF TOPICS FOR DISSERTATION

| | | |

|1 |Name of the Candidate and Address (in Block Letters) |Dr. UMAR NAZIR KABLI |

| | |POST GRADUATE STUDENT, |

| | |DEPARTMENT OF MEDICINE, |

| | |COMMAND HOSPITAL, AIR FORCE |

| | |BENGALURU, KARNATAKA. |

|2 |Name of the Institution |COMMAND HOSPITAL, AIR FORCE |

| | |BENGALURU, KARNATAKA. |

|3 |Course of Study and Subject |Post-graduate |

| | |M.D. MEDICINE |

|4 |Date of Admission to Course |01-07-2013 |

| | | |

|5 |Title of the Topic |STUDY OFCLINICAL AND IMAGING PROFILE IN VARIOUS TYPES OF THYROTOXICOSIS |

| |

|6. Brief resume of the intended work: |

| |

|Aim of the Study: |

|To study the clinical and imaging profile in armed forces patients population . |

| |

|6.2 Objective: |

|(i) To study the imaging profile in various types of thyrotoxicosis patients. |

|(ii) Special emphasis of various pattern of nuclear medicine imaging abnormalities in various types of thyrotoxicosis presentations. |

|6.3 Need for the study: |

|Thyrotoxicosis is a reasonably common clinical entity in all strata of patient population leading to lot of morbidity and mortality despite of all available modern |

|and accurate diagnostic techniques. This is most commonly due to delayed clinical diagnosis and subsequent treatment leading to complications.Best part of this |

|condition is that it is potentially curable disease with specific modalities of conservative therapy. |

|The annual incidence of the disease is 0.5 cases per 1000 persons during a 20-year period, with the peak occurrence in people aged 10-50 years. All thyroid diseases |

|occur more frequently in women than in men. An American study reported a prevalence of about 400 per 100,000 persons, with a lifetime risk of 1% in men and up to 2% |

|in women. 60-80% of cases are due to Graves' disease with a peak onset at 10-50 years; the remainder of cases are due largely to nodular thyroid disease that appears|

|later in life. It affects females more than males (ratio 9:1).A Scottish study found an incidence of 0.77/1,000 annually in women and 0.14/1,000 annually in men.In |

|England the incidence of Graves' disease has been reported as 0.5 per 1,000 per year.Thyrotoxicosis is less common in children than in adults. |

|Recent work has estimated the incidence of thyrotoxicosis at 80/100,000 per year in women and 8/100,000 per year in men. Studies specifically estimating the |

|incidence in childhood have been reported in Sweden (0·7/100,000 per year, ................
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