Appendix A1: Summary of 150 administrative database ...



Appendix A1: Summary of 150 administrative database studies included in this review.

|Reference |1st Author |Year |Journal |Impact |Design |Codes Used|

| | | | |Factor | | |

|1 |Gouya |2007 |European Journal of Epidemiology |2.6 |Cohort |Yes |

|2 |Depont |2007 |Pharmacoepidemiology & Drug Safety |2.5 |Cohort |No |

|3 |Bérard |2007 |British Journal of Clinical Pharmacology |3.1 |Cohort |Yes |

|4 |Kinsler |2007 |Sexually Transmitted Diseases |2.9 |Cross Sectional |No |

|5 |Castagnini |2007 |Psychopathology |1.4 |Cohort |Yes |

|6 |Desai |2002 |Pediatric Infectious Disease Journal |3.2 |Cross Sectional |Yes |

|7 |Clark |2002 |Schizophrenia Bulletin |6.6 |Cohort |Yes |

|8 |Christensen |2002 |Acta Odontologica Scandinavica |1.1 |Cohort |No |

|9 |Sato |2002 |Vaccine |3.3 |Cohort |Yes |

|10 |Reid |2002 |Oral Oncology |2.9 |Cohort |Yes |

|11 |Dreyer |1998 |Epidemiology |5.4 |Cohort |Yes |

|12 |Rosenthal |1997 |American Journal of Public Health |4.2 |Cohort |Yes |

|13 |Friis |1997 |Journal of Infectious Diseases |5.7 |Cohort |Yes |

|14 |Coleman |1998 |Ophthalmic Epidemiology |1.4 |Cohort |Yes |

|15 |Mattes |1997 |European Journal of Vascular & Endovascular Surg. |3 |Cohort |Yes |

|16 |Prentice |2007 |Health Services Research |2.7 |Cohort |Yes |

|17 |Gallerani |2007 |Chronobiology International |3.5 |Cohort |Yes |

|18 |Schneider |2007 |European Journal of Cancer Care |1 |Cohort |Yes |

|19 |Ismailov |2007 |Journal of Trauma-Injury Infection & Critical Care |2.3 |Case-Control |Yes |

|20 |Côté |2007 |Arthritis & Rheumatism |6.8 |Cohort |Yes |

|21 |Levin |2007 |Journal of the American College of Radiology |. |Cross Sectional |Yes |

|22 |Livingston |2007 |Journal of Gastrointestinal Surgery |2.3 |Cohort |Yes |

|23 |Gleason |2007 |Journal of Managed Care Pharmacy |1.5 |Cross Sectional |Yes |

|24 |Brinton |2007 |Gynecologic Oncology |2.9 |Cohort |Yes |

|25 |Oestreicher |2007 |Pharmacoepidemiology & Drug Safety |2.5 |Cohort |No |

|26 |Guo |2008 |Value in Health |3 |Cohort |Yes |

|27 |Guillaume |2008 |Journal of Clinical Pharmacy & Therapeutics |1.8 |Cross Sectional |No |

|28 |Polinder |2008 |Accident Analysis & Prevention |. |Cohort |Yes |

|29 |Borzecki |2008 |Journal of the National Medical Association |0.9 |Cohort |Yes |

|30 |Kim |2008 |European Journal of Cancer Care |1 |Cohort |No |

|31 |Richardson |2008 |Diabetes Care |7.3 |Cohort |Yes |

|32 |Setoguchi |2008 |Journal of the American College of Cardiology |11.4 |Cohort |Yes |

|33 |Roumie |2008 |Stroke |6.5 |Cohort |Yes |

|34 |Frayne |2008 |Medical Care |3.2 |Cross Sectional |No |

|35 |Gao |2008 |Journal of Public Health |1.1 |Cohort |Yes |

|36 |Jensen |2008 |American Journal of Epidemiology |5.5 |Cohort |Yes |

|37 |Dimick |2008 |Journal of Vascular Surgery |3.8 |Cohort |Yes |

|38 |Mattila |2008 |Pain |6 |Cohort |Yes |

|39 |Kronman |2008 |Journal of General Internal Medicine |2.7 |Cohort |Yes |

|40 |Strömberg |2008 |Clinical Gastroenterology & Hepatology |6.1 |Cohort |Yes |

|41 |Bramness |2008 |Journal of Clinical Psychiatry |5.1 |Cohort |No |

|42 |Moster |2008 |New England Journal of Medicine |50 |Cohort |Yes |

|43 |Welton |2008 |Policy, Politics, & Nursing Practice |. |Cross Sectional |No |

|44 |Loughnan |2008 |International Journal of Health Geographics |. |Cohort |Yes |

|45 |Wang |2008 |American Journal of Gastroenterology |6.4 |Cohort |Yes |

|46 |Aylin |2008 |Clinical Medicine |1.2 |Cross Sectional |Yes |

|47 |Weiss |2008 |Acta Orthopaedica |1.8 |Cohort |Yes |

|48 |Souayah |2008 |Journal of Clinical Neuromuscular Disease |. |Cross Sectional |Yes |

|49 |Wu |2008 |Am. Journal of Respiratory & Critical Care Medicine |9.8 |Cohort |Yes |

|50 |Buchanan |2008 |American Journal of Transplantation |6.6 |Cohort |Yes |

|51 |Raleigh |2008 |BMJ |12.8 |Cohort |Yes |

|52 |Pakyz |2008 |Archives of Internal Medicine |9.1 |Cohort |Yes |

|53 |Graham |2008 |American Heart Journal |4.3 |Cohort |Yes |

|54 |Goldfield |2008 |Health Care Financing Review |0.7 |Cohort |Yes |

|55 |Parner |2008 |Archives of Pediatrics & Adolescent Medicine |4.3 |Cohort |Yes |

|56 |Ferraz |2008 |Pan American Journal of Public Health |. |Cohort |No |

|57 |Cedrone |2008 |Ophthalmic Epidemiology |1.4 |Cross Sectional |Yes |

|58 |Lofwall |2008 |Journal of Nervous & Mental Disease |1.8 |Cross Sectional |No |

|59 |Foster |2008 |BMC Women's Health |. |Cohort |Yes |

|60 |Juarez |2008 |International Family Planning Perspectives |. |Cross Sectional |Yes |

|61 |Taylor |1997 |Journal of Neurosurgery |2.1 |Cohort |Yes |

|62 |Miller |1997 |American Journal of Industrial Medicine |. |Cohort |Yes |

|63 |Anderson |1997 |Medical Care |3.2 |Cohort |Yes |

|64 |Currie |1997 |Stroke |6.5 |Cohort |Yes |

|65 |McCusker |1997 |Academic Emergency Medicine |2.5 |Cohort |No |

|66 |Barnett |1997 |Medical Care |3.2 |Cohort |Yes |

|67 |Rosenman |1997 |Health Economics |2 |Cohort |No |

|68 |Friis |1997 |Annals of Plastic Surgery |1.1 |Cohort |Yes |

|69 |Karlson |1997 |Gastroenterology |12.6 |Cohort |Yes |

|70 |Wray |1997 |Medical Care |3.2 |Cross Sectional |Yes |

|71 |Williams |1997 |International Journal of Epidemiology |5.8 |Cross Sectional |Yes |

|72 |Lauderdale |1997 |American Journal of Epidemiology |5.5 |Cohort |Yes |

|73 |Wideroff |1997 |Journal of the National Cancer Institute |14.9 |Cohort |Yes |

|74 |Poloniecki |1997 |Occupational & Environmental Medicine |3.3 |Cohort |Yes |

|75 |Säynäjäkangas |1997 |Respiratory Medicine |2.3 |Cohort |Yes |

|76 |Harju |1997 |International Journal of Circumpolar Health |0.8 |Cohort |Yes |

|77 |Lipscomb |1997 |American Journal of Industrial Medicine |. |Cohort |Yes |

|78 |Preston |1997 |Journal of the American Geriatrics Society |3.8 |Cross Sectional |Yes |

|79 |Johnson |1997 |Medical Care |3.2 |Cross Sectional |No |

|80 |Krasnik |1997 |Danish Medical Bulletin |1.6 |Cohort |No |

|81 |Adib |1997 |Lebanese Medical Journal |. |Cohort |No |

|82 |Jollis |1997 |Circulation |14.6 |Cohort |Yes |

|83 |Gadomski |1998 |Pediatrics |4.8 |Cohort |Yes |

|84 |Kauppi |1997 |Cancer Causes & Control |3.7 |Case-Control |Yes |

|85 |Delfino |1998 |Environmental Research |3 |Cohort |Yes |

|86 |Long |1998 |American Journal of Public Health |4.2 |Cohort |No |

|87 |Currie |1998 |Diabetes Care |7.3 |Cohort |Yes |

|88 |Gray |1998 |American Journal of Tropical Medicine & Hygiene |2.5 |Cohort |Yes |

|89 |Rudolph |1998 |Wisconsin Medical Journal |. |Cohort |Yes |

|90 |Ray |1998 |Chest |5.2 |Cohort |Yes |

|91 |Thompson |1998 |American Journal of Psychiatry |10.5 |Cohort |Yes |

|92 |Peek-Asa |1998 |Accident Analysis & Prevention |. |Cohort |Yes |

|93 |Waller |1998 |Burns |1.6 |Cohort |Yes |

|94 |Menke |1998 |Medical Care |3.2 |Cohort |Yes |

|95 |Reichman |1998 |Family Planning Perspectives |. |Cohort |No |

|96 |Zito |1998 |Journal of Child & Adolescent Psychopharmacology |2.6 |Cohort |No |

|97 |Bloom |1998 |Clinical Therapeutics |3.1 |Cohort |No |

|98 |Udom |1998 |Health Affairs |3.2 |Cross Sectional |Yes |

|99 |Siddique |1998 |American Journal of Public Health |4.2 |Cohort |Yes |

|100 |Forjuoh |1998 |Journal of Burn Care & Rehabilitation |. |Cohort |Yes |

|101 |Siegel |1998 |American Journal of Hypertension |3.1 |Cohort |No |

|102 |Rosen |1998 |American Journal of Medical Quality |1.4 |Cohort |Yes |

|103 |Schoenbaum |1998 |Psychiatric Services |2.5 |Cohort |No |

|104 |Maynard |1998 |Psychiatric Services |2.5 |Cross Sectional |Yes |

|105 |Li |1998 |Academic Emergency Medicine |2.5 |Cross Sectional |No |

|106 |Campbell |2002 |American Journal of Epidemiology |5.5 |Cohort |Yes |

|107 |Libby |2002 |Journal of Health Care Finance |. |Cohort |Yes |

|108 |Jones |2002 |Journal of Affective Disorders |3.3 |Cohort |Yes |

|109 |Dillingham |2002 |Archives of Physical Medicine & Rehabilitation |2.2 |Cross Sectional |Yes |

|110 |Pickard |2002 |Cancer |5.2 |Cohort |Yes |

|111 |Karjalainen |2002 |Int. Arch. of Occupational & Environmental Health |1.9 |Cohort |No |

|112 |Khaykin |2002 |Heart |5 |Cohort |Yes |

|113 |Lee |2002 |Health Services Management Research |. |Cross Sectional |Yes |

|114 |Weiderpass |2002 |International Journal of Cancer |4.7 |Cohort |Yes |

|115 |Rodrigues |2002 |Canadian Journal of Cardiology |1.8 |Cohort |Yes |

|116 |Ng |2002 |Annals of the Academy of Medicine, Singapore |1 |Cohort |No |

|117 |Mahomed |2003 |Journal of Bone & Joint Surgery - American Volume |3.3 |Cohort |Yes |

|118 |Munker |2003 |Acta Psychiatrica Scandinavica |3.5 |Cross Sectional |Yes |

|119 |Wang |2002 |Journal of the American Geriatrics Society |3.8 |Cohort |Yes |

|120 |Nelson |2002 |Pediatric Infectious Disease Journal |3.2 |Cohort |Yes |

|121 |Cowan |2003 |Journal of Vascular Surgery |3.8 |Cohort |Yes |

|122 |Nichols |2003 |Diabetes Care |7.3 |Cross Sectional |Yes |

|123 |Braback |2003 |Acta Paediatrica |1.5 |Cohort |Yes |

|124 |Jin |2002 |International Journal of Circumpolar Health |0.8 |Cohort |Yes |

|125 |Dunnigan |2003 |BMJ |12.8 |Cohort |No |

|126 |Stein |2003 |Archives of Internal Medicine |9.1 |Cross Sectional |Yes |

|127 |Render |2003 |Medical Care |3.2 |Cohort |No |

|128 |Rabaneck |2003 |American Journal of Gastroenterology |6.4 |Cohort |Yes |

|129 |Conner |2003 |American Journal of Public Health |4.2 |Cohort |Yes |

|130 |Finlayson |2003 |Archives of Surgery |4.3 |Cohort |Yes |

|131 |Hendryx |2003 |Journal of Behavioral Health Services & Research |. |Cohort |No |

|132 |Sanderson |2003 |Annals of Epidemiology |2.6 |Cohort |Yes |

|133 |Dimick |2003 |Archives of Surgery |4.3 |Cross Sectional |Yes |

|134 |Holman |2003 |Pediatrics |4.8 |Cross Sectional |Yes |

|135 |Dembe |2003 |American Journal of Industrial Medicine |. |Cross Sectional |No |

|136 |Ackermann |2003 |American Journal of Preventive Medicine |3.8 |Cohort |No |

|137 |Braunstein |2003 |Journal of the American College of Cardiology |11.4 |Cross Sectional |Yes |

|138 |Liu |2003 |American Surgeon |1.3 |Cohort |Yes |

|139 |Tuchsen |2003 |Annals of the Rheumatic Diseases |7.2 |Cohort |Yes |

|140 |O'Connor |2003 |BMC Family Practice |. |Cohort |Yes |

|141 |Moride |2003 |Rheumatology |4.1 |Cohort |No |

|142 |Lapointe |2003 |Pharmacotherapy |2.5 |Cohort |No |

|143 |Eskandar |2003 |Journal of Neurosurgery |2.1 |Cohort |Yes |

|144 |Dewa |2003 |British Journal of Psychiatry |5.1 |Cohort |No |

|145 |Deshpande |2003 |Archives of Disease in Childhood |2.8 |Cohort |Yes |

|146 |Bernstein |2003 |American Journal of Gastroenterology |6.4 |Case-Control |No |

|147 |Paikal |2002 |Ophthalmology |5.3 |Cross Sectional |Yes |

|148 |Gjesdal |2002 |European Journal of Public Health |2.2 |Cohort |No |

|149 |Gunnell |2002 |British Journal of Psychiatry |5.1 |Cohort |Yes |

|150 |Su |2003 |American Journal of Orthopedics |. |Cohort |Yes |

Appendix A2: Summary of all studies that used diagnostic or procedural codes to define cohort, exposure, or outcome.

|Study |Variable |Variable |Condition |Coding |Code |Validated? |

| |Group |Type | |System | | |

|1 |Dx |C |Acute myocardial infarction |ICD-9 |410 (including ST-segment elevation |No |

| | | | | |myocardial infarction and non | |

| | | | | |ST-segment elevation myocardial | |

| | | | | |infarction) | |

|3 |Dx |O |Pregnancy |ICD-9 |236.1; 630.0-648.9; 650.0-650.9; |No |

| | | | | |760.0-779.9 | |

|5 |Dx |C |Other psychoses |ICD-8 |298.0; 298.1; 298.2; 298.3; 298.8; |No |

| | | | | |298.9 | |

|6 |Proc |C |Myringotomy with tube insertion |ICD-9 CM |20.01 |No |

|7 |Dx |C |Schizophrenia and schizoaffective |NR |NR |No |

| | | |disorder | | | |

|9 |Dx |C |Hospitalization discharge |ICD-9 CM |All codes from 001 – 999 categorized |No |

| | | |diagnostic categories | |by type | |

|10 |Dx |C |Comorbidities |ICD-9 CM |NR |No |

|11 |Dx |C |Acute myocardial infarction |ICD-8 | 410 |No |

|12 |Dx |C |Acute myocardial infarction; |ICD-9 CM |NR |No |

| | | |congestive heart failure; | | | |

| | | |pneumonia; influenza; chronic | | | |

| | | |obstructive lung disease; stroke; | | | |

| | | |hip fracture | | | |

|13 |Dx |C |Condylomata acuminata |ICD-8 |99.9 |No |

|14 |Proc |C |Intraocular or laser glaucoma |ICD-9 and |ICD-9: 1264; 1254; 1260; 1261; 1262; |No |

| | | |surgery |HSPCS/CPT |1287; 1288; 1255; 1271; 1272; 1273; | |

| | | | |procedure |1274; 1298; 1255; 1271; 1272; 1273; | |

| | | | |codes |1274; 1298; 1266; 1282; 1251; 1252; | |

| | | | | |1253; 1259; 1263; 1265; 1269; 1279 | |

| | | | | |HSPCS/CPT: 65850; 66170; 66172; | |

| | | | | |66150; 66155; 66160; 67255; 66180; | |

| | | | | |66700; 6 | |

|15 |Proc |C |Sympathectomy, |ICPM |ICPM code: 5051; 5052; 5380; 5381; |Yes |

| | | |thromboendarterectomy, bypass |(1980-87);|5392 ICD-9 CM: 0523; 0532; (0531); | |

| | | |grafting |ICD-9 CM |3800; 3804; 3806; 3808; 3814; 3816; | |

| | | | |(1988-92) |3818; 3925; 3929 | |

|16 |Dx |C |Diagnostic groups |NR |NR |No |

|17 |Dx |C |Pulmonary embolism |ICD-9 CM |415.1, 634.6, 635.6, 637.6, 638.6, |No |

| | | | | |637.2 | |

|18 |Dx |C |Colon, lung, prostate, and breast|ICD-10 |C18-C21; C33 and C34; C61; C50 |No |

| | | |cancer | | | |

|19 |Dx |E |Thoracic trauma; blunt cardiac |ICD-9 CM |807.0-807.4; 839.61-839.71; 848.3; |No |

| | | |injury | |848.4; 860-862; 875; 879.0; 879.1; | |

| | | | | |901; 927.0; 922.1; 942.x1-942.x2; | |

| | | | | |861.01 | |

|20 |Dx |C |Comorbidities |ICD-9 |NR |No |

|21 |Proc |C |Catheter angiography; MR or CT |Current |75710; 75716; 75630; 73725; 73225; |No |

| | | |angiography |Procedural|73706; 73206; 75635 | |

| | | | |Terminolog| | |

| | | | |y | | |

|22 |Dx |C |Cholelithiasis; other disorders of|NR |574.xx; 575.x; 576.x |No |

| | | |gallbladder; other disorder of | | | |

| | | |biliary tract | | | |

|23 |Dx |C |Pneumonia; bronchitis; sinusitis; |ICD-9 CM |480.xx-486.xx; 466.xx; 461.xx; |No |

| | | |respiratory tract infection; | |460.xx; 462.xx-465.xx; 032.xx-034.xx;| |

| | | |influenza; asthma; COPD; cough | |487.xx; 493.xx; 490.xx-492.xx; | |

| | | | | |494.xx; 496.xx; 786.0x-786.49 | |

|24 |Dx |C |Gallbladder disease; diabetes; |ICD-10 |DK80; DE10-DE14; DH36.0; |No |

| | | |hypertension; thyroid disease; | |DO24.0-DO24.3; DI10-DI15; DE00-DE07; | |

| | | |obesity | |DE66 | |

|26 |Dx |C |Affective disorder; cyclothymia |ICD-9 |296.xx; 301.13 |No |

|28 |Dx |C |Injury related diagnosis as |ICD-9; |ICD-9: 800-995; ICD-10 S00-T78 |No |

| | | |principal admission code |ICD-10 | | |

| | | |(excluding injury due to medical | | | |

| | | |adverse events, early | | | |

| | | |complications, or late effects of | | | |

| | | |injury) | | | |

|29 |Dx |C |Atrial fibrillation |ICD-9 CM |427.3x |Yes |

|31 |Dx |C |Diabetes |ICD-9 |250.xx |Yes |

|32 |Dx |C |Myocardial infarction |ICD-9 |410 as primary or secondary dx with |Yes |

| | | | | |LOS 3+ days | |

|33 |Dx |O |Ischemic stroke, intracerebral |ICD-9 CM |433.x1; 434 [excl. 434.x0]; 436; 431;|Yes |

| | | |hemorrhage, subarachnoid | |430 | |

| | | |hemorrhage | | | |

|35 |Dx |C |Colorectal cancer |ICD-9 |153; 154 |No |

|36 |Dx |C |Infertility |ICD-8; |628 DN97 |No |

| | | | |ICD-10 | | |

|37 |Proc |C |Open or endovascular aortic repair|ICD-9 CM |38.44; 39.71 |No |

|38 |Dx |O |Low back pain |ICD-8; |ICD-10: M51.1; M54.5; M54.9 ICD-9: |No |

| | | | |ICD-9; |7227C; 7245A; 7249x ICD-8: 7287; | |

| | | | |And ICD-10|7170; 7288; 7251; 3530 | |

|39 |Dx |O |COPD, congestive heart failure |ICD-9 CM |491.xx; 492.xx; 493.xx; 496.xx; |No |

| | | | | |428.xx | |

|40 |Proc |C |Endoscopic retrograde |Swedish |9014, UJK02, UJK05, UJK12, UJK15 for |No |

| | | |cholangiopancreatography with |classifica|ERCP or 5388, 5394, JKE02, JKE12, | |

| | | |endoscopic sphincterotomy |tion of |JKE15, JKE18, JKE25, JKE98 | |

| | | | |Operations| | |

| | | | |and Major | | |

| | | | |Procedures| | |

|42 |Dx |O |Cerebral palsy |ICD-9; |342-4 |Yes |

| | | | |ICD-10 | | |

|44 |Dx |C |Acute myocardial infarction |ICD-10 |121.1; 121.2; 121.3; 121.4; 121.-9 |No |

|45 |Proc |C |Esophagomyotomy |ICD-9 CM |42.7 |No |

|46 |Dx |C |Pulmonary embolism |ICD-10 |26.0; 26.9 |No |

|47 |Dx |C |Tibial shaft fractures: closed, |ICD-10 |S82.20; S82.21; S82.2 |No |

| | | |open, and unspecified | | | |

|48 |Dx |C |Guillain-Barré syndrome |ICD-9 |357 |No |

|49 |Dx |C |Asthma |ICD-9 |493  |Yes |

|50 |Dx |e |Kidney transplant |DRG |302 |No |

|51 |Dx |C |Iatrogenic pneumothorax; decubitus|ICD-10 |"Details of the coding used in this |No |

| | | |ulcer; selected infections due to | |paper are available on request" | |

| | | |medical care; postoperative hip | | | |

| | | |fracture; postoperative sepsis; | | | |

| | | |obstetric trauma | | | |

|52 |Dx |C |Urinary tract infections; |ICD-9 CM |NR |No |

| | | |pneumonias; bloodstream | | | |

| | | |infections; solid organ | | | |

| | | |transplants; bone marrow | | | |

| | | |transplants | | | |

|53 |Dx |C |Acute coronary syndrome |ICD-9 CM |410.x; 411.1 |No |

|54 |Dx |C |All Patient Refined Diagnosis |APR DRG |NR |No |

| | | |Related Groups -determined either| | | |

| | | |by principal diagnosis or for | | | |

| | | |surgical patients, the most | | | |

| | | |important surgical procedure | | | |

| | | |performed | | | |

|55 |Dx |C |Autism spectrum disorder |ICD-10 |F84.0; F84.1; F84.5; F84.8; F84.9 |No |

|57 |Dx |C |Endophthalmitis; corneal ulcer; |ICD-9 CM |360.0 and subcategories; 370.0; 871 |No |

| | | |open wounds of the eyeball | | | |

|59 |Dx |C |Esophagitis ; Dysphagia; Reflux; |ICD-9 CM |530.10-530.12, 530.19; 787.2x; |No |

| | | |Gastric ulcer; Peptic ulcer; | |530.81; 531.00, 531.01, 531.10, | |

| | | |Gastric ulcer; Gastritis; DVT/PE; | |531.11, 531.20, 531.21, 531.30, | |

| | | |Fractures; Breast Cancer ; | |531.31, 531.40, 531.41, 531.50, | |

| | | |Endocrine disease; HIV; Liver | |531.51, 531.60, 531.61, 531.70, | |

| | | |disease; Bone Cancer; Other | |531.71, 531.90, 531.91; 533.00, | |

| | | |Cancer; Alcoholism; | |533.01, 533.10, 533.11, 533.20, | |

| | | |Osteodystrophy; Nephritis; | |533.21, 533.30, 533.31, 533.40, | |

| | | |Rheumatoid Arthritis; | |533.41, 533.50, 533.51, 533.60, | |

| | | |Cardiovascular Disease ; Thyroid | |533.61, 533.70, 533.71, 533.90, | |

| | | |Disease; Metabolic Disorders ; | |533.91; 534.00, 534.01, 534.10, | |

| | | |Osteoporosis | |534.11, 534.20, 534.21, 534.30, | |

| | | | | |534.31, 534.40, 534.41, 534.50, | |

| | | | | |534.51, 534.60, 534.61, 534.70, | |

| | | | | |534.71, 534.90, 534.91; 535.00, | |

| | | | | |535.01, 535.30, 535.31, 535.40, | |

| | | | | |535.41, 535.50, 535.51; | |

| | | | | |453.40-453.42, 453.8, 415.1x; | |

| | | | | |79.0-79.3, 79.6, 733.1x, | |

| | | | | |805.xx-806.xx, 807.0x-807.3x, | |

| | | | | |808.xx-815.xx, 818.xx-825.xx, 827.xx,| |

| | | | | |828.xx; : 174.x, 175.x, 238.3, 239.3;| |

| | | | | |250-259; 042, 043, 044, V08; 070, | |

| | | | | |570-573; 170.0 – 170.9; 140.x – | |

| | | | | |208.x, 230.x-239.x, except 170.x, | |

| | | | | |174.x175.x, 172-173.x; 303.x; 756.5; | |

| | | | | |580.xx-589.9; 714.0x, 714.1x, 714.2x,| |

| | | | | |714.3x; 410.xx-414.xx; 240-246.9; | |

| | | | | |270-278.8; 733.00-733.03, 733.09 | |

|60 |Dx |C |Abortion complications |ICD-10 |NR |No |

|61 |Dx |C |Subarachnoid hemorrhage |ICD-9 CM |430 |No |

|62 |Dx |C |Upper and lower extremity |American |NR |No |

| | | |fractures, dislocations, and joint|National | | |

| | | |ruptures; other upper extremity |Standards | | |

| | | |injuries; back sprains and strains|Institutes| | |

| | | | |coding | | |

| | | | |system | | |

|63 |Dx |C |HIV disease |ICD-9 CM |42.xx-44.xx |No |

|64 |Dx |C |Diabetes |ICD-9 |250 |Yes |

|66 |Dx |C |All hospitalization |DRG |NR |No |

| | | |diagnosis-related groups | | | |

|68 |Proc |C |Breast augmentation |ICD-8 |385.00 |No |

| | | | |(Danish-mo| | |

| | | | |dified | | |

| | | | |version) | | |

|69 |Dx |C |Acute, chronic or unspecified |ICD-7; |ICD-7: 587.21-587.23, 587.28; |No |

| | | |pancreatitis |ICD-8 |587.00-587.02, 587.09; 587.10, | |

| | | | | |598.19-587-20 ICD-8: 577.09, | |

| | | | | |577.91-577.93, 577.98; 577.00-577.02,| |

| | | | | |577.08; 577,10, 577.19, 577.90 | |

|70 |Dx |C |Chronic obstructive pulmonary |DRG |88; 89-91, 96-98;127; 121-123, 132, |No |

| | | |disease; heart failure; angina | |133, 138, 139, 140; 15, 134, 180, | |

| | | |pectoris; simple pneumonia and | |181, 202, 277-279, 294, 295, 320-322,| |

| | | |pleurisy; cardiac arrhythmia and | |323, 324, 395, 396; 82, 99, 100; 141,| |

| | | |conduction disorders; diabetes; | |142, 143; 12, 14, 18, 19, 188-190, | |

| | | |cellulitis; kidney and urinary | |331-333, 463, 464 | |

| | | |tract infections; acute myocardial| | | |

| | | |infarction; transient ischemic | | | |

| | | |attacks; hypertension; | | | |

| | | |atherosclerosis; bronchitis and | | | |

| | | |asthma; urinary stones; cirrhosis | | | |

| | | |and alcoholic hepatitis; red blood| | | |

| | | |cell disorders; gastrointestinal | | | |

| | | |obstruction | | | |

|71 |Dx |C |Diseases of the respiratory system|ICD-9 CM |161, 162.0-162.5, 466.0, 466.1, 463, |No |

| | | | | |472.0, 474.0, 477.0-477.9, 480.0, | |

| | | | | |480.1, 480.2, 480.8, 480.9, 485, 486,| |

| | | | | |487.0-487.8, 490, 491.0-491.2, | |

| | | | | |492.0-492.8, 493.0, 493.1, 493.9, | |

| | | | | |494, 496, 500-508.9, 510.0-510.9, | |

| | | | | |511.0-511.9, 512.0-512.8, | |

| | | | | |513.0-513.1, 514, 515 | |

|72 |Dx |C |Hip fracture |ICD-9 CM |820.0-820.9 |No |

|73 |Dx |C |Diabetes |ICD-8; |(ICD-8) 250 |No |

| | | | |Danish | | |

| | | | |National | | |

| | | | |Board of | | |

| | | | |Health | | |

| | | | |codes that| | |

| | | | |distinguis| | |

| | | | |hed IDDM | | |

| | | | |and NIDDM | | |

|74 |Dx |O |Circulatory system diseases |ICD-9 |390-459 |No |

|75 |Dx |C |Bronchiectasis |ICD-8; |ICD-8: 518 ICD-9: 494 |No |

| | | | |ICD-9 | | |

|76 |Dx |C |Asthma |ICD-8; |  |No |

| | | | |ICD-9 | | |

|77 |Dx |C |Sprain/strain: back, neck, back |American |NR |No |

| | | |and neck, shoulder, elbow, |National | | |

| | | |wrist/forearm, hand/finger, knee, |Standards | | |

| | | |or ankle/lower leg; contusion: |Institutes| | |

| | | |hand/finger, knee, or foot/toes; |coding | | |

| | | |fracture: hand/finger or |system | | |

| | | |foot/toes; ill-defined back | | | |

| | | |symptoms; nerve condition of the | | | |

| | | |wrist forearm | | | |

|78 |Proc |C |Mammography |Current |76090; 76091; 76092 |No |

| | | | |Procedural| | |

| | | | |Terminolog| | |

| | | | |y | | |

|82 |Proc |C |Angioplasty |Current |  |No |

| | | | |Procedural| | |

| | | | |Terminolog| | |

| | | | |y | | |

|83 |Dx |O |Avoidable pediatric admissions |ICD-9 CM |493, 008.4, 008.6, 008.8, 276, 558.9,|Yes |

| | | | | |25, 250.11, 055, 033, 320.0, 382, | |

| | | | | |383, 460, 465.9, 466.0, 599.0, | |

| | | | | |590.1-9, 614, 773.1, 774.2, 774.3, | |

| | | | | |774.6, 774.7, 276.0, 276.5, 751.2, | |

| | | | | |751.3, 751.4, 751.5, 560.9, 777.1, | |

| | | | | |745.0-745.1, 746.0-746.8, | |

| | | | | |747.1-747.3, 779.3, 7 | |

|84 |Dx |C |Rheumatoid arthritis; Primary or |NR |NR |No |

| | | |Secondary Sjögren's syndrome | | | |

|85 |Dx |O |URTI, Bronchitis, Pneumonia, COPD,|ICD-9 CM |NR |No |

| | | |Asthma | | | |

|87 |Dx |C |Diabetes |ICD-9 |250 |Yes |

|88 |Dx |C |Coccidioidomycosis |ICD-9 CM |114.0-114.9 |No |

|89 |Dx |C |Diabetes |DRG |294 295 |No |

|90 |Dx |C |Asthma |ICD-9 CM | 493 |No |

|91 |Dx |C |Depression |ICD-9 CM |296.2; 296.3; 300.4; 309.0; 309.1 |No |

|92 |Dx |C |Traffic-related injury |ICD-9 E |810-829 |No |

|93 |Dx |C |Burn; contact with fire and |ICD N-code|N940-949; E890-899; E924; E958.1, |No |

| | | |flames; contact with hot object or| |E958.2; E968.0, E968.3; E988.1, | |

| | | |substance, caustic or corrosive | |E988.2; | |

| | | |material, or steam; self-inflicted| | | |

| | | |burn; assault by means of fire or | | | |

| | | |hot liquid | | | |

|94 |Dx |C |COPD; primary respiratory |DRG |88; 82; 294-295; 121-123; 144-145; |No |

| | | |neoplasms; diabetes; acute | |127; 14-15; 174-175; 202; 320-321; | |

| | | |myocardial infarction; congestive | |159-162; 39; 106-107; 306-307, | |

| | | |heart failure; cerebrovascular | |336-337; 109-112; 146-149; 75; 209; | |

| | | |disease; GI bleeding; cirrhosis | |430; 429; 12; 434-437; 425; 427 | |

| | | |and alcoholic hepatitis; | | | |

| | | |pyelonephritis; hernia procedures;| | | |

| | | |lens procedures; CABG; | | | |

| | | |transurethral prostate | | | |

|98 |Dx |C |Cesarean section without |DRG |371; 373 |No |

| | | |complications; vaginal delivery | | | |

| | | |without complications | | | |

|99 |Dx |C |Pulmonary embolism |ICD-9 CM | 415.1 |No |

|100 |Dx |C |Fire or burn diagnosis |ICD-9 CM |940.0-949.9; 910-917; 919; 692.71 |No |

|102 |Dx |C |Asthma |ICD-9 CM |493.x0-493.x1 |No |

|104 |Dx |C |Alcohol use disorders; drug use |ICD-9 CM |NR |No |

| | | |disorders; senility and organic | | | |

| | | |mental disorders; affective | | | |

| | | |disorders; schizophrenia and | | | |

| | | |related disorders; other | | | |

| | | |psychoses; anxiety, somatoform, | | | |

| | | |and personality disorders; | | | |

| | | |preadult disorders; other mental | | | |

| | | |conditions; and personal history | | | |

| | | |of mental disorders | | | |

|106 |Dx |o |Bell's palsy |ICD-9 CM |351 |No |

|107 |Dx |o |Depression; adjustment reaction; |ICD-9 CM |296, 311; 309; 314; 312, 313 |No |

| | | |attention deficit/hyperactivity | | | |

| | | |disorder; oppositional defiant and| | | |

| | | |conduct disorders | | | |

|108 |Dx |c |Major depressive disorder; |DSM-III; |NR |No |

| | | |dysthymia; anxiety disorder; |DSM-IV | | |

| | | |depression NOS | | | |

|109 |Proc |o |Lower limb amputation |ICD-9 CM |84.11-84.19 |No |

|110 |Dx |c |Hyperparathyroidism |ICD-8 |252.00-252.09 |No |

|112 |Dx |c |Acute myocardial infarction |ICD-9 |410 |Yes |

|113 |Dx |o |Pulmonary compromise; acute |NR |NR |No |

| | | |myocardial infarction; | | | |

| | | |gastrointestinal bleed or | | | |

| | | |ulceration; venous thrombosis or | | | |

| | | |pulmonary embolism; urinary tract | | | |

| | | |infection; pneumonia | | | |

|114 |Dx |c |Diabetes |ICD-7; |ICD-7: 260 ICD-8: 250 |No |

| | | | |ICD-8 | | |

|115 |Dx |c |Acute myocardial infarction |ICD-9 | 410 |No |

|117 |Proc |c |Elective primary total hip |ICD-9 CM; |ICD-9 CM: 81.51 CPT: 27134, 27137, |Yes |

| | | |arthroplasty; revision total hip |CPT |27138 | |

| | | |arthroplasty | | | |

|118 |Dx |o |Substance related admissions |ICD-8; |ICD-8: 291, 303, 304.09, 304.59, |No |

| | | | |ICD-10 |304.49, 304.69, 304.79, 304.89, | |

| | | | | |304.99 ICD-10: DF10-DF19 | |

|119 |Dx |C |Urinary incontinence |ICD-9 |344.61, 596.5x, 788.3x |No |

|120 |Dx |C |Intussusception |ICD-9 | 560 |No |

|121 |Proc |C |Thoracoabdominal aortic aneurysm |ICD-9 CM |384.4; 384.5 |No |

| | | |repair | | | |

|122 |Dx |o |Depression |ICD-9 CM |296.2x 296.3x 298.0 300.4 309.1 311.0|No |

|123 |Dx |o |Asthma; bronchitis; |ICD-9 |493; 466; 009 |No |

| | | |gastroenteritis | | | |

|124 |Dx |C |Diabetes |ICD-9 |250, 648.0, 775.0 or 775.1 |No |

|126 |Dx |c |Deep vein thrombosis; pulmonary |ICD-9 CM |451.1, 451.2, 451.8, 451.9, 453.2, |No |

| | | |embolus | |453.8, 453.9, 671.3, 671.4, 671.9; | |

| | | | | |415.1, 634.6, 635.6, 636.6, 637.6, | |

| | | | | |638.6, 673.2 | |

|128 |Dx |c |Colorectal cancer |ICD-9 CM |153.0-153.4 153.6-154.1 |No |

|129 |Dx |c |Injury |ICD-9 CM |800-999 |No |

|130 |Proc |C |Resection of cancer |ICD-9 |NR |No |

|132 |Dx |c |Alzheimer’s dementia |ICD-9 CM |290.0-290.43, 290.8-290.9, 291.2, |No |

| | | | | |291.82, 294.1, 310.10, 331.0-331.9, | |

| | | | | |332.0-332.1, 333.4 | |

|133 |Proc |C |Esophageal resection |ICD-9 CM |NR |No |

|134 |Dx |c |Kawasaki syndrome |ICD-9 CM | 446.1 |No |

|137 |Dx |c |Chronic heart failure |ICD-9 |398.91, 428, 428.0, 428.1, 428.9 |No |

|138 |Proc |c |Gastric bypass surgery |ICD-9 CM | 44.31 |. |

|139 |Dx |o |Coxarthrosis |ICD-8; |ICD-8: 713.00; ICD10: M16 |Yes |

| | | | |ICD-10 | | |

|127 |Dx |C |Diabetes |ICD-9 CM |250.xx |Yes |

|143 |Dx |c |Parkinson's disease; secondary |ICD-9 CM |332.0; 332.1 |No |

| | | |Parkinson’s disease | | | |

|145 |Dx |c |Bronchiolitis; lower respiratory |ICD-10 |J21.0, J21.8, J21.9; J10-18, J20-22 |No |

| | | |tract infection | | | |

|147 |Proc |c |Laser trabeculoplasty; |HCPCS |65855; 66170,66172 |No |

| | | |trabeculectomy | | | |

|149 |Dx |o |Psychosis |ICD-9; |ICD-9: 295, 297-99; ICD-10: F20-F29 |No |

| | | | |ICD-10 | | |

|150 |Dx |c |Femoral neck fracture |ICD-9 |820.0-820.9 |No |

Appendix A3 – Summary of all studies using validated code.

|Study |Validation |Code Used in Study* |How Validated |Disease or |Disease |Sens-itivi|Spec-ifici|+’ve |-’ve |

| |Study | |Code Differed |Code** |Prevalence in |ty |ty |Predict-ive|Predict-ive|

| | | |From Study Code|Prevalence in |Validation | | |Value |Value |

| | | | |Study | | | | | |

|15 |15 |0523 0532 0531 3800 |Same |NR |0.99 |NR |NR |0.99 |NR |

| | |3804 3806 3808 3814 | | | | | | | |

| | |3816 3818 3925 3929 | | | | | | | |

| | |8414 8415 8416 8417 | | | | | | | |

| | |(ICPM) | | | | | | | |

|29 |151 |427.3x |Same |0.053 |0.062 |0.80 |0.99 |0.84 |0.99 |

|31 |152 |250.xx in 2+ outpatient|Same |0.2 |0.2 |0.73 |0.98 |0.90 |0.94 |

| | |records | | | | | | | |

|32 |153 |410 as 1° or 2° |410.x1 as 1° or|NR |0.94 |NR |NR |0.94 |NR |

| | |diagnosis with LOS 3+ |2° diagnosis | | | | | | |

| | |days |with LOS 3+ | | | | | | |

| | | |days | | | | | | |

|33 |154 |433.x1; 434 [but not |Same |0.013** |0.97 |NR |NR |0.97 |NR |

| | |434.x0]; 436; 431; 430 | | | | | | | |

|42 |155 |342-4 |Validated Code |0.002 |0.035 |0.70 |0.99 |0.83 |0.99 |

| | | |Not Reported | | | | | | |

|83 |83 |Avoidable pediatric |Same |NR |0.97 |NR |NR |0.97† |NR |

| | |admissions | | | | | | | |

|87 |156 |250.xx |Same |0.012** |0.99 |NR |NR |0.99 |NR |

|64 |156 |250.xx |Same |0.033** |0.99 |NR |NR |0.99 |NR |

|112 |157 |410 as MRD, age 20-100,|Same |NR |0.97 |NR |NR |0.97†† |NR |

| | |and not admitted to | | | | | | | |

| | |non-cardiac surgical | | | | | | | |

| | |service, transferred | | | | | | | |

| | |from another hospital, | | | | | | | |

| | |AMI within previous | | | | | | | |

| | |year, or discharged | | | | | | | |

| | |alive ................
................

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