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Adverse Effects. Associated with the effects of the drugs on CNS (CNS) and PNS: Sedation, orthostatic hypotension, GI anticholinergic effects such as dry mouth, constipation, nausea, vomiting, anorexia, weight gain (a reason people stop therapy), hallucinations, cardiac dysrhythmia. MUST have baseline ECG, and yearly follow up ECG. Drug Interactions ................
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