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is a PGE1 analog which restores the cytoprotective effect to GI mucosa (mainly maintaining vascular tone and blood flow which prevents epithelial damage and necrosis). To avoid some of the side effects caused by COX-1 inhibition, there is a new class of drugs called coxibs. or . COX-2 selective inhibitors. These drugs include . celecoxib. and ... ................
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