GENETICS DISORDER RESEARCH PROJECT
Sandhoff’s Disease – Defect in both Hexosaminidase A & B. Build up of both GM2 and globoside lead to mental retardation, cherry red macula, rapid progression and early death. Tay-Sachs Disease – Defect in Hexosaminidase A. Buildup of GM2 leads to cherry red macula, blindness, mental retardation. ................
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