MANUAL ON UNIFORM TRAFFIC CONTROL DEVICES

2) Lipid diffusion: through membrane driven by conc grad; must be lipid soluble, though must be dissolved in water in order to reach membrane. 3) Facilitated diffusion (via carriers): eg. Needed to cross BBB, for weak acids in PCT of kidney. 4) Pinocytosis (receptor mediated endocytosis): for drugs MW>1000. Factors Affecting Drug Permeation ................
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