Irradiated Blood Products - Transfusion Guidelines
Irradiated
Blood
Products
Michelle Lannon
Haem SpR
Coming Up
Why does blood need to be irradiated? Who needs irradiated products?
What happens if they get non-irradiated products?
Whose responsibility is it anyway?
What condition are we trying to prevent when we irradiate?
Lymphocytes in the transfused blood `look around' the body of the recipient and realise it is foreign to them ? this puts them into attack mode.
In immunocompetent patients: the recipient's own lymphocytes mount a counter attack, and being in the majority, will win.
In immunocompromised patients: the recipient's own lymphocytes are absent or useless and thus the invading lymphocytes take over; the attack continues!
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