Royal Australian College of General Practitioners
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KEY MEDICAL JOURNALS – JULY 2020
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British Medical Journal Vol. 369 No. 8247 May 30 2020
Covid-19: Questions of conscience and duty for scientific advisers m2102
Covid-19: Selected NHS patients will be treated with remdesivir m2097
Covid-19: Intensive care consultant has suspension cut short to help fight pandemic m2040
Seven days in medicine: 20-26 May 2020 m2074
Sixty seconds on . . . the draggle m2075
Covid-19: Deadline for roll out of UK’s tracing app will be missed m2085
Covid-19: Delaying school reopening by two weeks would halve risks to children, says iSAGE m2079
Anosmia: Five minutes with ENT consultant Claire Hopkins m2095
Covid-19 and thrombosis: what do we know about the risks and treatment? m2058
Covid-19: UK’s response has so far cost “unprecedented” £124.3bn m2057
Covid-19: Brazil now has third highest number of cases behind US and Russia m2059
Covid-19 and alcohol—a dangerous cocktail m1987
Public inquiry into UK’s response to covid-19 m2052
What the NHS is learning from the British army in the covid-19 crisis m2055
The positive effects of covid-19 m1785
Research on covid-19 is suffering “imperfect incentives at every stage” m2045
Waste in covid-19 research m1847
Research
Invasive breast cancer and breast cancer mortality after ductal carcinoma in situ in women attending for breast screening in England, 1988-2014: population based observational cohort study m1570
Financial ties between leaders of influential US professional medical associations and industry: cross sectional study m1505
Financial relations between leaders of US medical societies and industry m1811
National, regional, and worldwide epidemiology of psoriasis: systematic analysis and modelling study m1590
Comment
Clare Gerada: Some good must come out of covid-19 m2043
Protecting “covid protected” cancer hubs m2062
David Oliver: Doughnut deliveries, hospital staff, and the pandemic m2042
Helen Salisbury: Battening down the hatches for a second wave m2076
Ethics of reallocating ventilators in the covid-19 pandemic m1828
Covid-19: Important potential side effects of wearing face masks that we should bear in mind m2003
Urgency and uncertainty: covid-19, face masks, and evidence informed policy m2017
Efficacy of face masks depends on spatial relation between host and recipient and who is being protected m2016
Social distancing for covid-19: is 2 metres far enough? m2010
Covid-19: Each discarded face mask is a potential biohazard m2012
Face masks in the covid-19 crisis: caveats, limits, and priorities m2030
Variable uptake of face masks could reinforce health inequalities m2001
Covid-19: are face masks a good long term strategy? m2005
Covid-19: face masks could foster distrust and blame m2009
Inesa Benedictovna Kozlovskaya: expert on motor control and space medicine m1363
Education
Covid-19 and cardiovascular disease m1997
Is surveillance colonoscopy necessary for all patients with bowel polyps? m1706
It felt like I was living in a fog m923
Losing weight following diagnosis of type 2 diabetes boosts chance of remission l6775
Myocardial infarction at night . . . and other stories m2036
Careers
Why I . . . run m1394
British Medical Journal Vol. 369 No. 8248 June 6 2020
Covid-19: It’s too soon to lift lockdown m2202
Covid-19: GPs angry they were not told about changes to shielding advice m2196
NHS launches Race and Health Observatory after BMJ’s call to end inequalities m2191
Seven days in medicine: 27 May to 2 Jun 2020 m2185
Sixty seconds on . . . the clap m2183
Covid-19: 146 researchers raise concerns over chloroquine study that halted WHO trial m2197
Covid-19: Easing lockdown could risk second spike, say public health doctors m2193
Covid-19: Doctors need proper mental health support, says BMA m2192
US to withdraw from WHO as China has “total control” over it, Trump claims m2178
Covid-19: How does the NHS test and trace service work? m2174
Covid-19: Two thirds of people contacted through tracing did not fully cooperate, pilot scheme finds m2169
Covid-19: Frontline doctors continue PPE fight m2188
Shielding from covid-19 should be stratified by risk m2063
Can the UK emulate the South Korean approach to covid-19? m2084
Should governments continue lockdown to slow the spread of covid-19? m1924
How mental health services are adapting to provide care in the pandemic m2106
Physician Moms Group: the support network that’s needed more than ever during the covid-19 pandemic m1499
What the Diamond Princess taught the world about covid-19 m1632
The “virtual wards” supporting patients with covid-19 in the community m2119
Research
Use of all cause mortality to quantify the consequences of covid-19 in Nembro, Lombardy: descriptive study
m1835
Clinical efficacy of hydroxychloroquine in patients with covid-19 pneumonia who require oxygen: observational comparative study using routine care data m1844
Hydroxychloroquine in patients with mainly mild to moderate coronavirus disease 2019: open label, randomised controlled trial m1849
Lack of efficacy of hydroxychloroquine in covid-19 m2018
Comment
Partha Kar: Covid-19—time for parity in commissioning diabetes services m2154
Duty to treat: where do the limits lie? m2150
David Oliver: Covid-19 has highlighted the NHS’s strengths and weaknesses m2124
Helen Salisbury: Testing times for GPs m2180
Covid-19: the ethics of clinical research in quarantine m2060
Rapid mobilisation of research in response to covid-19: a paradigm for the future m2155
Expanding the definition of covid-19 deaths will show the true effect of the pandemic m2153
Ethnicity and covid-19: analysis must be inclusive and transparent m2166
Let’s not forget our female front line m2167
Covid-19 in care homes: the many determinants of this perfect storm m2096
Care homes after covid-19: we need a wide ranging inquiry and reform m2105
Care homes after covid-19: the government needs a plan m2101
Care home reforms should prioritise quality of life m2121
Covid-19 and refugees, asylum seekers, and migrants in Greece m2168
Irene Marion Desmet: pioneering neonatal surgeon m1397
Education
Mitigating the psychological effects of social isolation during the covid-19 pandemic m1904
Group cognitive behavioural courses may reduce fatigue from rheumatoid arthritis m512
Losing my licence meant I lost my independence m1405
Type 1 diabetes and environment . . . and other stories m2104
Careers
How can I make the most of working from home? m2120
British Medical Journal Vol. 369 No. 8249 June 13 2020
Racism: the other pandemic m2303
Covid-19: Risk of second wave is very real, say researchers m2294
Sisters can claim compensation after seeing father die from undiagnosed heart disease, says judge m2262
Seven days in medicine: 3-9 June 2020 m2267
Sixty seconds on . . . wingman lounges m2258
Data transparency: “Nothing has changed since Tamiflu” m2279
BMA urges plan to tackle backlog of patients awaiting non-covid treatment m2238
Covid-19: Hydroxychloroquine does not benefit hospitalised patients, UK trial finds m2263
Hospital staff take the knee in Boston m2278
Covid-19: PHE review has failed ethnic minorities, leaders tell BMJ m2264
Ethnicity and covid-19 m2282
Covid-19: ensuring equality of access to testing for ethnic minorities m2122
Ethical road map through the covid-19 pandemic m2033
Too slow and fundamentally flawed: why test and trace is a weak and inequitable defence against covid-19 m2246
How covid-19 is accelerating the threat of antimicrobial resistance m1983
Risky Business: lessons from covid-19 m2221
Research
Characterization and clinical course of 1000 patients with coronavirus disease 2019 in New York: retrospective case series m1996
Factors associated with hospital admission and critical illness among 5279 people with coronavirus disease 2019 in New York City: prospective cohort study m1966
Incidence, clinical outcomes, and transmission dynamics of severe coronavirus disease 2019 in California and Washington: prospective cohort study m1923
Covid-19 related hospital admissions in the United States: needs and outcomes m2082
Comment
Using socioeconomics to counter health disparities arising from the covid-19 pandemic m2149
Rammya Mathew: We must not be guided by bad science on covid-19 m2241
There is no stopping covid-19 without stopping racism m2244
David Oliver: The structural problems highlighted by covid-19 m2214
Helen Salisbury: Just say sorry m2260
Covid-19: democracy and hard choices in public health m2090
Reimagining healthcare after covid-19: a new normal for medicine m2220
Covid-19 and ethnicity: it’s too early to point to healthcare provider attitudes as a cause of poorer outcomes
m2181
Laying straw men to rest: author’s reply to “Urgency and uncertainty: covid-19, face masks, and evidence informed policy” m2240
William Brumfitt: pioneer of modern microbiology m1495
Education
Covid-19 and acute kidney injury in hospital: summary of NICE guidelines m1963
Fractures of the scaphoid m1908
CME
Children with pulsus paradoxus . . . and other stories m2207
Careers
Serving meals and mopping floors: the consultant psychiatrist working differently during the covid-19 pandemic
m2218
British Medical Journal Vol. 369 No. 8250 June 20 2020
Rashford, racism, and bankrupt excuses m2432
Covid-19: Low dose steroid cuts death in ventilated patients by one third, trial finds m2422
Minimum pricing in Scotland leads to fall in alcohol sales m2324
Seven days in medicine: 10-16 June m2409
Sixty seconds on . . . bubbles m2381
Covid-19: Woman whose father died in care home launches legal review over government’s “litany of failures”
m2405
Covid-19: Racism may be linked to ethnic minorities’ raised death risk, says PHE m2421
Covid-19: Urgent cancer referrals fall by 60%, showing “brutal” impact of pandemic m2386
New observatory will set out actions to tackle racism “within months,” say campaigners m2395
Covid-19: NHS Test and Trace releases first figures, with experts calling for improvements m2404
Doctors call for meeting to clarify why president resigned from Royal College of Physicians of Edinburgh m2387
Covid-19: People in most deprived areas of England and Wales twice as likely to die m2389
World leaders in covid-19 control m2411
How Northern Ireland relaunched contact tracing for covid-19 a month before the rest of the UK m2373
Children are being sidelined by covid-19 m2061
Obesity and covid-19: the role of the food industry m2237
Even covid-19 can’t kill the anti-vaccination movement m2184
Hydroxychloroquine for covid-19: the end of the line? m2378
Risks to health and the NHS in the post-Brexit era m2307
Research
Scope, quality, and inclusivity of clinical guidelines produced early in the covid-19 pandemic: rapid review
m1936
Kawasaki-like multisystem inflammatory syndrome in children during the covid-19 pandemic in Paris, France: prospective observational study m2094
Pediatric inflammatory syndrome temporally related to covid-19 m2123
Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study m1985
Comment
Matt Morgan: Covid-19 and the need for bold decisions m2320
Covid-19: The communication needs of D/deaf healthcare workers and patients are being forgotten m2372
David Oliver: Let’s be open and honest about covid-19 deaths in care homes m2334
Helen Salisbury: Missing the silence m2402
How a US-UK trade agreement could affect NHS drug prices m1332
“Women and children last”—effects of the covid-19 pandemic on reproductive, perinatal, and paediatric health
m2287
Risks to children during the covid-19 pandemic: some essential epidemiology m2290
Collateral damage of the covid-19 pandemic: a Dutch perinatal perspective m2326
Violence against women in the covid-19 pandemic: we need upstream approaches to break the intergenerational cycle m2327
Pernicious anaemia: self-administration of hydroxocobalamin in the covid-19 crisis m2380
Pernicious anaemia: switch to oral B12 supplementation to reduce risk of covid-19 transmission m2383
Minding the epistemic gap in covid-19 and beyond m2379
Distinguishing between direct and indirect consequences of covid-19 m2377
Creating misinformation: how a headline in The BMJ about covid-19 spread virally m2384
Judith Darmady: supercharged childcare visionary m1988
Education
Assessment and management of adults with asthma during the covid-19 pandemic m2092
Tranexamic acid is safe to use following mild-to-moderate traumatic brain injury m514
Twenty miles per hour speed zones reduce the danger to pedestrians and cyclists m453
Epilepsy at all ages . . . and other stories m2309
Careers
Why I . . . dance m2247
British Medical Journal Vol. 369 No. 8251 June 27 2020
Covid 19: Where’s the strategy for testing? m2518
Covid-19: Demand for dexamethasone surges as RECOVERY trial publishes preprint
Covid-19: Health and care workers will be “highest priority” for vaccination, says JCVI m2477
Seven days in medicine: 17-23 June 2020 m2501
Sixty seconds on . . . the two metre rule m2507
Covid-19: Local health teams trace eight times more contacts than national service m2486
Covid-19: UK drops its own contact tracing app to switch to Apple and Google model m2472
Covid-19: Ethnic minority doctors feel more pressured and less protected than white colleagues, survey finds
m2506
Covid-19: Researchers question policy of closing schools after finding under 20s have low susceptibility to virus m2439
Five minutes with . . . Aarti Bansal m2483
Covid-19: Public health agencies review whether vitamin D supplements could reduce risk m2475
NHS health checks should start at age 25 for BAME patients, MPs hear m2462
Covid-19: Footballers mark silent respect for victims m2504
Tackling UK’s mortality problem: covid-19 and other causes m2295
Covid-19 and ethnic minorities: an urgent agenda for overdue action m2503
Covid-19 antibody tests: a briefing m2284
Why covid-19 antibody tests are not the game changer the UK government claims m2469
Rapid roll out of SARS-CoV-2 antibody testing—a concern m2420
Commercial influence and covid-19 m2456
Research
Characteristics and outcomes of pregnant women admitted to hospital with confirmed SARS-CoV-2 infection in UK: national population based cohort study m2107
Use of an electronic decision support tool to reduce polypharmacy in elderly people with chronic diseases: cluster randomised controlled trial m1822
Inappropriate medication use and polypharmacy in older people m2023
Academic criteria for promotion and tenure in biomedical sciences faculties: cross sectional analysis of international sample of universities m2081
Comment
Clare Gerada: What to do with appraisal m2450
NHS Test and Trace: it didn’t have to be this way m2471
David Oliver: Preventing more deaths in care homes in a second pandemic surge m2461
Helen Salisbury: When will we be well again? m2490
The economy of wellbeing: what is it and what are the implications for health? m1874
Covid-19: now is not the time to judge the UK’s response m2448
UK’s response to covid-19: crude, unadjusted mortality figures are not the whole storym2453
Covid-19: public health expertise is being sidelined m2454
UK response to covid-19: obfuscation, misrepresentation, and ignoring advice m2455
Education
Computerised speech and language therapy can help people with aphasia find words following a stroke m520
Recurrent vulvovaginal candidiasis m1995
CME
Hypospadias m2070
Pedometers can help people get more active as part of an exercise programme m877
Predicting multiple sclerosis progression . . . and other stories m2437
Careers
How can I make the most of my time shielding? m2443
JAMA Vol. 323 No. 21 June 2 2020
Sasson DC, Kashanian JA.
Varicoceles.
p2210. doi:10.1001/jama.2020.0397. PMID: 32484535.
Man S, Xian Y, Holmes DN, et al.
Association Between Thrombolytic Door-to-Needle Time and 1-Year Mortality and Readmission in Patients With Acute Ischemic Stroke.
pp2170-2184. doi:10.1001/jama.2020.5697. PMID: 32484532.
Kuppermann M, Kaimal AJ, Blat C, et al.
Effect of a Patient-Centered Decision Support Tool on Rates of Trial of Labor After Previous Cesarean Delivery: The PROCEED Randomized Clinical Trial.
pp2151-2159. doi:10.1001/jama.2020.5952. PMID: 32484533.
von Dach E, Albrich WC, Brunel AS, et al.
Effect of C-Reactive Protein-Guided Antibiotic Treatment Duration, 7-Day Treatment, or 14-Day Treatment on 30-Day Clinical Failure Rate in Patients With Uncomplicated Gram-Negative Bacteremia: A Randomized Clinical Trial.
pp2160-2169. doi:10.1001/jama.2020.6348. PMID: 32484534.
Drugs for Depression.
pp2188-2189. doi:10.1001/jama.2020.3040. PMID: 32484531.
Bruckner JM.
Securing the Sails.
pp2143-2144. doi:10.1001/jama.2020.7164. PMID: 32484537.
Voelker R.
Triple-Negative Breast Cancer Drug Receives Approval.
p2122. doi:10.1001/jama.2020.8312. PMID: 32484522.
Voelker R.
Hemodialysis Device for Very Small Pediatric Patients.
p2122. doi:10.1001/jama.2020.8778. PMID: 32484524.
Voelker R.
e-Cigarette Hoodies and Backpacks Prompt FDA Warnings.
p2122. doi:10.1001/jama.2020.8313. PMID: 32484523.
Fact and Opinion on the Present Epidemic of Respiratory Disease.
p2207. doi:10.1001/jama.2020.6391. PMID: 32484526.
Flanagin A, Bauchner H, Fontanarosa PB.
Patient and Study Participant Rights to Privacy in Journal Publication.
pp2147-2150. doi:10.1001/jama.2020.3590. PMID: 32484519.
Long MT, Kory P, Marik P.
Vitamin C, Hydrocortisone, and Thiamine for Septic Shock.
pp2203-2204. doi:10.1001/jama.2020.5844. PMID: 32484528.
Fujii T, Udy AA, Bellomo R.
Vitamin C, Hydrocortisone, and Thiamine for Septic Shock-In Reply.
pp2204-2205. doi:10.1001/jama.2020.5850. PMID: 32484530.
Akresh-Gonzales J.
I Remember Wells of Nausea Worse Than Pain.
p2206. doi:10.1001/jama.2020.1990. PMID: 32484536.
Hampton T.
Do Gut Bacteria Play a Role in Preeclampsia?
pp2120-2121. doi:10.1001/jama.2020.4755. PMID: 32484518.
Qian YY, Hu LH, Liao Z.
Surgery vs Endoscopy for Early Treatment of Chronic Pancreatitis.
p2202. doi:10.1001/jama.2020.4823. PMID: 32484527.
Kempeneers MA, Bruno MJ, Boermeester MA.
Surgery vs Endoscopy for Early Treatment of Chronic Pancreatitis-Reply.
p2203. doi:10.1001/jama.2020.4826. PMID: 32484529.
Muth CC.
Long-term Outcomes After Thrombolytic Therapy for Acute Ischemic Stroke.
pp2184-2185. doi:10.1001/jama.2020.5269. PMID: 32484521.
Swamy GK, Grotegut CA.
Can a Structured, Electronic Approach to Shared Decision-making Increase Attempted Trial of Labor?
pp2145-2146. doi:10.1001/jama.2020.5947. PMID: 32484520.
JAMA Vol. 323 No. 22 June 9 2020
Hamiel U, Kozer E, Youngster I.
SARS-CoV-2 Rates in BCG-Vaccinated and Unvaccinated Young Adults.
pp2340-2341. doi:10.1001/jama.2020.8189. PMID: 32401274; PMCID: PMC7221856.
Sartini C, Tresoldi M, Scarpellini P, et al.
Respiratory Parameters in Patients With COVID-19 After Using Noninvasive Ventilation in the Prone Position Outside the Intensive Care Unit.
pp2338-2340. doi:10.1001/jama.2020.7861. PMID: 32412606; PMCID: PMC7229533.
Abbasi J.
Existing Drugs Might Treat COVID-19.
p2239. doi:10.1001/jama.2020.9265. PMID: 32515802.
Smith BM, Kirby M, Hoffman EA, et al.
Association of Dysanapsis With Chronic Obstructive Pulmonary Disease Among Older Adults.
pp2268-2280. doi:10.1001/jama.2020.6918. PMID: 32515814; PMCID: PMC7284296.
Elharrar X, Trigui Y, Dols AM, et al.
Use of Prone Positioning in Nonintubated Patients With COVID-19 and Hypoxemic Acute Respiratory Failure.
pp2336-2338. doi:10.1001/jama.2020.8255. PMID: 32412581; PMCID: PMC7229532.
US Preventive Services Task Force, Krist AH, Davidson KW, et al.
Screening for Unhealthy Drug Use: US Preventive Services Task Force Recommendation Statement.
pp2301-2309. doi:10.1001/jama.2020.8020. PMID: 32515821.
Randhawa AK, Fisher LH, Greninger AL, et al.
Changes in SARS-CoV-2 Positivity Rate in Outpatients in Seattle and Washington State, March 1-April 16, 2020.
pp2334-2336. doi:10.1001/jama.2020.8097. PMID: 32383728; PMCID: PMC7210505.
Patnode CD, Perdue LA, Rushkin M, et al.
Screening for Unhealthy Drug Use: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.
pp2310-2328. doi:10.1001/jama.2019.21381. PMID: 32515820.
Abbasi J.
Bionic Arm With Real-Time Sensation.
p2239. doi:10.1001/jama.2020.8836. PMID: 32515801.
Levis B, Sun Y, He C, et al.
Accuracy of the PHQ-2 Alone and in Combination With the PHQ-9 for Screening to Detect Major Depression: Systematic Review and Meta-analysis.
pp2290-2300. doi:10.1001/jama.2020.6504. PMID: 32515813; PMCID: PMC7284301.
Kuehn BM.
Homeless Shelters Face High COVID-19 Risks.
p2240. doi:10.1001/jama.2020.8854. PMID: 32515823.
Jin J.
Screening for Unhealthy Drug Use in Adults and Adolescents.
pp2350. doi:10.1001/jama.2020.8192. PMID: 32515816.
Kurth T, Rist PM, Ridker PM, et al.
Association of Migraine With Aura and Other Risk Factors With Incident Cardiovascular Disease in Women. pp2281-2289. doi:10.1001/jama.2020.7172. PMID: 32515815; PMCID: PMC7284297.
Immunization Against Plague: An Argument for Controlled Experiment.
p2347. doi:10.1001/jama.2019.13488. PMID: 32515807.
Hawes AM.
The Spectrum of Deaths Encountered by a Young Learner.
pp2260-2261. doi:10.1001/jama.2020.7083. PMID: 32515818.
Cutler D.
How Will COVID-19 Affect the Health Care Economy?
pp2237-2238. doi:10.1001/jama.2020.7308. PMID: 32515806.
Adler C.
An Early Result Acceptance Program for Residency Application.
pp2344-2345. doi:10.1001/jama.2020.6513. PMID: 32515810.
Hammoud MM, Andrews JS, Skochelak SE.
An Early Result Acceptance Program for Residency Application-Reply.
p2345. doi:10.1001/jama.2020.6516. PMID: 32515812.
Kuehn BM.
Spike in Poison Control Calls Related to Disinfectant Exposures.
p2240. doi:10.1001/jama.2020.8307. PMID: 32515822.
Abbasi J.
Blood Test Flags Multiple Cancers in Large Study.
p2239. doi:10.1001/jama.2020.9266. PMID: 32515803.
Thomas DM, Galbreath D, Boucher M, et al.
Revisiting Leonardo da Vinci's Vitruvian Man Using Contemporary Measurements.
pp2342-2343. doi:10.1001/jama.2020.3501. PMID: 32515808; PMCID: PMC7284298.
Saitz R.
Screening for Unhealthy Drug Use: Neither an Unreasonable Idea Nor an Evidence-Based Practice.
pp2263-2265. doi:10.1001/jama.2019.20152. PMID: 32515804.
Zwanenburg PR, Timmer AS, Boermeester MA.
Incisional Negative Pressure Wound Therapy After Surgery for Major Trauma-Related Fractures.
pp2343-2344. doi:10.1001/jama.2020.5847. PMID: 32515809.
Costa ML; WHIST Trial Collaborators.
Incisional Negative Pressure Wound Therapy After Surgery for Major Trauma-Related Fractures-Reply.
p2344. doi:10.1001/jama.2020.5853. PMID: 32515811.
JAMA Vol. 323 No. 23 June 16 2020
Young A.
Recurrence.
p2434. doi:10.1001/jama.2020.2464. PMID: 32543686.
Sood N, Simon P, Ebner P, et al.
Seroprevalence of SARS-CoV-2-Specific Antibodies Among Adults in Los Angeles County, California, on April 10-11, 2020.
pp2425-2427. doi:10.1001/jama.2020.8279. PMID: 32421144; PMCID: PMC7235907.
Hains DS, Schwaderer AL, Carroll AE, et al.
Asymptomatic Seroconversion of Immunoglobulins to SARS-CoV-2 in a Pediatric Dialysis Unit.
pp2424-2425. doi:10.1001/jama.2020.8438. PMID: 32407440; PMCID: PMC7226282.
Bunyavanich S, Do A, Vicencio A.
Nasal Gene Expression of Angiotensin-Converting Enzyme 2 in Children and Adults.
pp2427-2429. doi:10.1001/jama.2020.8707. PMID: 32432657; PMCID: PMC7240631.
Chiu RG, Mehta AI.
Spinal Metastases.
p2438. doi:10.1001/jama.2020.0716. PMID: 32543685.
Bond A.
Socially Distanced Medicine.
p2383. doi:10.1001/jama.2020.8975. PMID: 32543687.
Pratley RE, Kanapka LG, Rickels MR, et al.
Effect of Continuous Glucose Monitoring on Hypoglycemia in Older Adults With Type 1 Diabetes: A Randomized Clinical Trial.
pp2397-2406. doi:10.1001/jama.2020.6928. PMID: 32543682; PMCID: PMC7298607.
The "Sense" of Humor-Art & Science.
p2435. doi:10.1001/jama.2019.13477. PMID: 32543676.
McEvoy JW, Selvin E.
Pulse Pressure and Isolated Diastolic Hypertension-Reply.
pp2431-2432. doi:10.1001/jama.2020.5937. PMID: 32543680.
Anstadt GW.
Pulse Pressure and Isolated Diastolic Hypertension.
p2431. doi:10.1001/jama.2020.5931. PMID: 32543678.
Laffel LM, Kanapka LG, Beck RW, et al.
Effect of Continuous Glucose Monitoring on Glycemic Control in Adolescents and Young Adults With Type 1 Diabetes: A Randomized Clinical Trial.
pp2388-2396. doi:10.1001/jama.2020.6940. PMID: 32543683; PMCID: PMC7298603.
Kim BK, Hong SJ, Cho YH, et al.
Effect of Ticagrelor Monotherapy vs Ticagrelor With Aspirin on Major Bleeding and Cardiovascular Events in Patients With Acute Coronary Syndrome: The TICO Randomized Clinical Trial.
pp2407-2416. doi:10.1001/jama.2020.7580. PMID: 32543684; PMCID: PMC7298605.
Kuehn BM.
New Hypertension Guidelines Apply to Diverse Socioeconomic Settings.
p2363. doi:10.1001/jama.2020.9824. PMID: 32543690.
Voelker R.
New Drug Is a Triple Threat Against RET-Altered Cancer.
p2364. doi:10.1001/jama.2020.9790. PMID: 32543673.
Kuehn BM.
Study Explores Psychological Harm to Health Workers During Outbreaks.
p2363. doi:10.1001/jama.2020.8822. PMID: 32543689.
Voelker R.
Targeted Therapy and Diagnostic Test for Non-Small Cell Lung Cancer.
p2364. doi:10.1001/jama.2020.9429. PMID: 32543671.
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Genetic Analysis Tracks SARS-CoV-2 Mutations in Human Hosts.
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Gostin LO.
COVID-19 Reveals Urgent Need to Strengthen the World Health Organization.
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Home Noninvasive Positive Pressure Ventilation for Chronic Obstructive Pulmonary Disease.
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Home Noninvasive Positive Pressure Ventilation for Chronic Obstructive Pulmonary Disease-Reply.
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Agarwal S, Cappola AR.
Continuous Glucose Monitoring in Adolescent, Young Adult, and Older Patients With Type 1 Diabetes.
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Fourth-Line Treatment Approved For Gastrointestinal Tumor.
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JAMA Vol. 323 No. 24 June 23 2020
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Dog Bites.
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Clearness in Medical Speech.
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Pandemic Highlights Behavioral Health Disparities.
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Csizmadi I, Lin PH, Freedland SJ.
Vegetable Consumption and Progression of Prostate Cancer.
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Vegetable Consumption and Progression of Prostate Cancer.
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Vegetable Consumption and Progression of Prostate Cancer-Reply.
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Postpartum Depression Screening Needs More Consistency.
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Clopidogrel Noninferior to Ticagrelor With Less Bleeding.
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Laughter Leaves Me Lighter: Coping With COVID-19.
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Physical Therapy Outperforms Injections for Knee Osteoarthritis.
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Government Not Doing All It Could to Recruit and Retain Scientists.
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Cautious and Fearful Infants Grow Into Cautious and Fearful Adults.
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Clinical Genomics in Critically Ill Infants and Children.
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Prostate Cancer Drug Degarelix Rapidly Treats Pedophilic Disorder.
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Plant Extracts May Relieve Hangover Symptoms, Trial Suggests.
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C-Reactive Protein Test Reduces Antibiotics for COPD Flare-ups.
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Justice and health: The Lancet-Health Equity and Policy Lab Commission.
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Community participation is crucial in a pandemic.
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Electron microscopy of SARS-CoV-2: a challenging task.
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Use of herbal drugs to treat COVID-19 should be with caution.
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COVID-19 in Africa: no room for complacency.
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Offline: After COVID-19-is an "alternate society" possible?
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Devi S.
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Cost-effectiveness of transitional US plans for universal health care.
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Drusen in dense deposit disease: not just age-related macular degeneration.
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Kawasaki-like disease: emerging complication during the COVID-19 pandemic.
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COVID19-APHP Group.
Electronic address: martin.hirsch@aphp.fr. Assistance Publique-Hôpitaux de Paris' response to the COVID-19 pandemic.
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Journal of a plague year.
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Salient lessons from Russia's COVID-19 outbreak.
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Attacks against health-care personnel must stop, especially as the world fights COVID-19.
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Critically ill patients with COVID-19 in New York City.
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Regenerative medicine: challenges and opportunities.
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Healthier Societies For Healthy Populations Group. Healthier societies for healthy populations.
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Horton R.
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COVID-19 vaccine development pipeline gears up.
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Indigenous populations: left behind in the COVID-19 response.
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Lancet Vol. 395 No. 10240 June 13 2020
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Retraction-Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a
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Meningococcal disease and sexual transmission: urogenital and anorectal infections and invasive disease due to Neisseria meningitidis.
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Acute liver failure.
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COVID-19 vaccines for all?
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The Lancet Editors.
Expression of concern: Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis.
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Triple therapy for BRAFV600-mutated melanoma.
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Medicine and medical science: Black lives must matter more.
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Questioning statin therapy for older patients.
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Major burns: debt recovery or ethics?
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Revisiting the 1957 and 1968 influenza pandemics.
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Glynne-Jones R, Harrison M, Cheetham D.
NICE guideline for rectal cancer: already out of date.
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Aspirin for Lynch syndrome: a legacy of prevention.
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COVID-19 testing delays and pathology services in the UK.
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Increasing tobacco sales under the anti-smoking policy in China.
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Excess mortality in men and women in Massachusetts during the COVID-19 pandemic.
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A view from UK public health registrars on the challenges of COVID-19.
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Atrial septal defect and haemodynamic consequences of continuous positive airway pressure treatment.
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Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study.
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The Lancet Commission on dengue and other Aedes-transmitted viral diseases.
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Quantifying additional COVID-19 symptoms will save lives.
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HALT-IT Trial Collaborators.
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New directions in the treatment of opioid withdrawal.
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Global governance for COVID-19 vaccines.
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Have deaths from COVID-19 in Europe plateaued due to herd immunity?
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Alam N, Wright AK, Ashcroft DM, et al.
Cancer and cardiovascular disease.
pp1903-1904. doi:10.1016/S0140-6736(20)30222-1. PMID: 32563368.
Devi S.
COVID-19 resurgence in Iran.
p1896. doi:10.1016/S0140-6736(20)31407-0. PMID: 32563363; PMCID: PMC7302754.
Dervaux A.
Antipsychotics for schizophrenia and substance misuse.
p1902. doi:10.1016/S0140-6736(20)30237-3. PMID: 32563367.
Perner A, Møller MH.
Tranexamic acid for severe gastrointestinal bleeding.
pp1885-1886. doi:10.1016/S0140-6736(20)30975-2. PMID: 32563356.
Marchalik D, Petrov D.
Seeing COVID-19 through José Saramago's Blindness.
p1899. doi:10.1016/S0140-6736(20)31352-0. PMID: 32563364; PMCID: PMC7302777.
Strongman H, Lyon AR, Dos Santos Silva I, et al.
Cancer and cardiovascular disease - Authors' reply.
pp1904-1905. doi:10.1016/S0140-6736(20)30232-4. PMID: 32563371.
van Netten JJ, Bus SA, Schaper NC, et al.
Doing meaningful systematic reviews is no gravy train.
pp1905-1906. doi:10.1016/S0140-6736(20)30174-4. PMID: 32563372.
Lund H, Juhl C.
Doing meaningful systematic reviews is no gravy train.
p1905. doi:10.1016/S0140-6736(20)30172-0. PMID: 32563373.
Huhn M, Samara M, Leucht S.
Antipsychotics for schizophrenia and substance misuse - Authors' reply.
p1903. doi:10.1016/S0140-6736(20)30233-6. PMID: 32563369.
Horton R.
Offline: A novel solution to live with coronavirus.
p1894. doi:10.1016/S0140-6736(20)31416-1. PMID: 32563361; PMCID: PMC7302747.
Gasparini S, Torino C, Branca D, et al.
Testing rimegepant for migraine-time to revise the trial design?
p1901. doi:10.1016/S0140-6736(20)30241-5. PMID: 32563366.
Croop R, Goadsby PJ, Stock DA, et al.
Testing rimegepant for migraine-time to revise the trial design? - Authors' reply.
pp1901-1902. doi:10.1016/S0140-6736(20)30231-2. PMID: 32563365.
Boyce N, Brandon B, Merry G, et al.
Wakley Prize Essay 2020: medicine and plain truths in a pandemic year.
p1892. doi:10.1016/S0140-6736(20)31415-X. PMID: 32563359; PMCID: PMC7302787.
Zarocostas J.
Plain packaging ruling hailed as a victory for tobacco control.
p1895. doi:10.1016/S0140-6736(20)31406-9. PMID: 32563362.
Allen S, Cortina CS.
An unusual cause of breast hypertrophy: pseudoangiomatous stromal hyperplasia secondary to contraceptive implant.
p1937. doi:10.1016/S0140-6736(20)31283-6. PMID: 32563379.
Baker P, White A, Morgan R.
Men's health: COVID-19 pandemic highlights need for overdue policy action.
pp1886-1888. doi:10.1016/S0140-6736(20)31303-9. PMID: 32563357.
Palmer J.
Framing health stories: Highlights 2020 photography competition open for submissions.
p1893. doi:10.1016/S0140-6736(20)31414-8. PMID: 32563360; PMCID: PMC7302765.
Medical Journal of Australia Vol. 212 No. 10 June 2020
Caly L, Druce J, Roberts J, et al.
Isolation and rapid sharing of the 2019 novel coronavirus (SARS-CoV-2) from the first patient diagnosed with COVID-19 in Australia.
pp459-462. doi:10.5694/mja2.50569. PMID: 32237278; PMCID: PMC7228321.
Objectives: To describe the first isolation and sequencing of SARS-CoV-2 in Australia and rapid sharing of the isolate.
Setting: SARS-CoV-2 was isolated from a 58-year-old man from Wuhan, China who arrived in Melbourne on 19 January 2020 and was admitted to the Monash Medical Centre, Melbourne from the emergency department on 24 January 2020 with fever, cough, and progressive dyspnoea.
Major outcomes: Clinical course and laboratory features of the first reported case of COVID-19 (the illness caused by SARS-CoV-2) in Australia; isolation, whole genome sequencing, imaging, and rapid sharing of virus from the patient.
Results: A nasopharyngeal swab and sputum collected when the patient presented to hospital were each positive for SARS-CoV-2 (reverse transcription polymerase chain reaction). Inoculation of Vero/hSLAM cells with material from the nasopharyngeal swab led to the isolation of SARS-CoV-2 virus in culture. Electron microscopy of the supernatant confirmed the presence of virus particles with morphology characteristic of viruses of the family Coronaviridae. Whole genome sequencing of the viral isolate and phylogenetic analysis indicated the isolate exhibited greater than 99.99% sequence identity with other publicly available SARS-CoV-2 genomes. Within 24 hours of isolation, the first Australian SARS-CoV-2 isolate was shared with local and overseas reference laboratories and major North American and European culture collections.
Conclusions: The ability to rapidly identify, propagate, and internationally share our SARS-CoV-2 isolate is an important step in collaborative scientific efforts to deal effectively with this international public health emergency by developing better diagnostic procedures, vaccine candidates, and antiviral agents.
Weinkove R, McQuilten ZK, Adler J, et al.
Managing haematology and oncology patients during the COVID-19 pandemic: interim consensus guidance. pp481-489. doi:10.5694/mja2.50607. PMID: 32401360.
Introduction: A pandemic coronavirus, SARS-CoV-2, causes COVID-19, a potentially life-threatening respiratory disease. Patients with cancer may have compromised immunity due to their malignancy and/or treatment, and may be at elevated risk of severe COVID-19. Community transmission of COVID-19 could overwhelm health care services, compromising delivery of cancer care. This interim consensus guidance provides advice for clinicians managing patients with cancer during the pandemic.
Main recommendations: During the COVID-19 pandemic: In patients with cancer with fever and/or respiratory symptoms, consider causes in addition to COVID-19, including other infections and therapy-related pneumonitis. For suspected or confirmed COVID-19, discuss temporary cessation of cancer therapy with a relevant specialist. Provide information on COVID-19 for patients and carers. Adopt measures within cancer centres to reduce risk of nosocomial SARS-CoV-2 acquisition; support population-wide social distancing; reduce demand on acute services; ensure adequate staffing; and provide culturally safe care. Measures should be equitable, transparent and proportionate to the COVID-19 threat. Consider the risks and benefits of modifying cancer therapies due to COVID-19. Communicate treatment modifications, and review once health service capacity allows. Consider potential impacts of COVID-19 on the blood supply and availability of stem cell donors. Discuss and document goals of care, and involve palliative care services in contingency planning.
Changes in management as a result of this statement: This interim consensus guidance provides a framework for clinicians managing patients with cancer during the COVID-19 pandemic. In view of the rapidly changing situation, clinicians must also monitor national, state, local and institutional policies, which will take precedence.
Litton E, Bucci T, Chavan S, et al.
Surge capacity of intensive care units in case of acute increase in demand caused by COVID-19 in Australia. pp463-467. doi:10.5694/mja2.50596. PMID: 32306408; PMCID: PMC7264562.
Objectives: To assess the capacity of intensive care units (ICUs) in Australia to respond to the expected increase in demand associated with COVID-19.
Design: Analysis of Australian and New Zealand Intensive Care Society (ANZICS) registry data, supplemented by an ICU surge capability survey and veterinary facilities survey (both March 2020).
Settings: All Australian ICUs and veterinary facilities.
Main outcome measures: Baseline numbers of ICU beds, ventilators, dialysis machines, extracorporeal membrane oxygenation machines, intravenous infusion pumps, and staff (senior medical staff, registered nurses); incremental capability to increase capacity (surge) by increasing ICU bed numbers; ventilator-to-bed ratios; number of ventilators in veterinary facilities.
Results: The 191 ICUs in Australia provide 2378 intensive care beds during baseline activity (9.3 ICU beds per 100 000 population). Of the 175 ICUs that responded to the surge survey (with 2228 intensive care beds), a maximal surge would add an additional 4258 intensive care beds (191% increase) and 2631 invasive ventilators (120% increase). This surge would require additional staffing of as many as 4092 senior doctors (245% increase over baseline) and 42 720 registered ICU nurses (269% increase over baseline). An additional 188 ventilators are available in veterinary facilities, including 179 human model ventilators.
Conclusions: The directors of Australian ICUs report that intensive care bed capacity could be near tripled in response to the expected increase in demand caused by COVID-19. But maximal surge in bed numbers could be hampered by a shortfall in invasive ventilators and would also require a large increase in clinician and nursing staff numbers.
Brewster DJ, Chrimes N, Do TB, et al.
Consensus statement: Safe Airway Society principles of airway management and tracheal intubation specific to the COVID-19 adult patient group.
pp472-481. doi:10.5694/mja2.50598. PMID: 32356900.
Introduction: This statement was planned on 11 March 2020 to provide clinical guidance and aid staff preparation for the coronavirus disease 2019 (COVID-19) pandemic in Australia and New Zealand. It has been widely endorsed by relevant specialty colleges and societies.
Main recommendations: Generic guidelines exist for the intubation of different patient groups, as do resources to facilitate airway rescue and transition to the "can't intubate, can't oxygenate" scenario. They should be followed where they do not contradict our specific recommendations for the COVID-19 patient group. Consideration should be given to using a checklist that has been specifically modified for the COVID-19 patient group. Early intubation should be considered to prevent the additional risk to staff of emergency intubation and to avoid prolonged use of high flow nasal oxygen or non-invasive ventilation. Significant institutional preparation is required to optimise staff and patient safety in preparing for the airway management of the COVID-19 patient group. The principles for airway management should be the same for all patients with COVID-19 (asymptomatic, mild or critically unwell). Safe, simple, familiar, reliable and robust practices should be adopted for all episodes of airway management for patients with COVID-19.
Changes in management as a result of this statement: Airway clinicians in Australia and New Zealand should now already be involved in regular intensive training for the airway management of the COVID-19 patient group. This training should focus on the principles of early intervention, meticulous planning, vigilant infection control, efficient processes, clear communication and standardised practice.
Smith DW.
The challenges of establishing adequate capacity for SARS-CoV-2 testing.
pp457-458. doi:10.5694/mja2.50610. PMID: 32401351.
Wang JH, Tan S, Raubenheimer K.
Rethinking the role of senior medical students in the COVID-19 response.
p490-490.e1. doi:10.5694/mja2.50601. PMID: 32368797.
Goodsall TM, Costello SP, Bryant RV.
COVID-19 and implications for thiopurine use.
p490-490.e1. doi:10.5694/mja2.50613. PMID: 32400020.
Martin JH, Bowden NA.
Drug repurposing in the era of COVID-19: a call for leadership and government investment.
pp450-452.e1. doi:10.5694/mja2.50603. PMID: 32372435.
Fox GJ, Trauer JM, McBryde E.
Modelling the impact of COVID-19 on intensive care services in New South Wales.
pp468-469. doi:10.5694/mja2.50606. PMID: 32383153.
Meares HD, Jones MP.
When a system breaks: queueing theory model of intensive care bed needs during the COVID-19 pandemic. pp470-471. doi:10.5694/mja2.50605. PMID: 32379951.
Patel C, Chiu CK, Beard FH, et al.
One disease, two vaccines: challenges in prevention of meningococcal disease.
pp453-456.e1. doi:10.5694/mja2.50567. PMID: 32279307.
Dalton CB, Corbett SJ, Katelaris AL.
COVID-19: implementing sustainable low cost physical distancing and enhanced hygiene.
pp443-446.e1. doi:10.5694/mja2.50602. PMID: 32356573.
MacIntyre CR, Heslop DJ.
Public health, health systems and palliation planning for COVID-19 on an exponential timeline.
pp440-442.e1. doi:10.5694/mja2.50592. PMID: 32319114; PMCID: PMC7264606.
Rojek AM, Dutch M, Camilleri D, et al.
Early clinical response to a high consequence infectious disease outbreak: insights from COVID-19.
pp447-450.e1. doi:10.5694/mja2.50608. PMID: 32415678.
Medical Journal of Australia Vol. 212 No. 11 June 2020
Kovitwanichkanont T, Chong AH, Foley P.
Beyond skin deep: addressing comorbidities in psoriasis.
pp528-534. doi:10.5694/mja2.50591. PMID: 32388913.
Psoriasis is a chronic inflammatory disease that is commonly encountered in primary care and is associated with significant morbidity that extends beyond the skin manifestations. Psoriasis is associated with an elevated risk of psoriatic arthritis, cardiovascular disease, obesity, insulin resistance, mental health disorders, certain types of malignancy, inflammatory bowel disease and other immune-related disorders, and hepatic and renal disease. Enhanced recognition of these comorbidities may lead to earlier diagnosis and potentially better overall health outcomes. Psoriatic nail involvement, severe skin disease and obesity are associated with a greater risk of psoriatic arthritis. Individuals with psoriasis should be routinely screened for psoriatic arthritis to allow for early intervention to improve long term prognosis. Life expectancy is reduced in people with psoriasis due to a variety of causes, with cardiovascular disease and malignancy being the most common aetiologies. Psoriasis affects several factors that contribute to worsened quality of life and increased risk of depression and anxiety. Effective therapies are now available that have been shown to concurrently improve skin disease, quality of life and psychiatric symptoms. As the concordance between psychosocial impact and objective disease severity does not always correlate, it is essential to tailor management strategies specifically to the needs of each individual. Cigarette smoking and excess alcohol consumption are among the most important modifiable risk factors that increase the likelihood of psoriasis development and severity of skin disease. This provides a compelling rationale for smoking cessation and limiting alcohol intake in people with psoriasis beyond their traditional harmful health consequences.
Hill MG, Sim M, Mills B.
The quality of diagnosis and triage advice provided by free online symptom checkers and apps in Australia.
pp514-519. doi:10.5694/mja2.50600. PMID: 32391611.
Objectives: To investigate the quality of diagnostic and triage advice provided by free website and mobile application symptom checkers (SCs) accessible in Australia.
Design: 36 SCs providing medical diagnosis or triage advice were tested with 48 medical condition vignettes (1170 diagnosis vignette tests, 688 triage vignette tests).
Main outcome measures: Correct diagnosis advice (provided in first, the top three or top ten diagnosis results); correct triage advice (appropriate triage category recommended).
Results: The 27 diagnostic SCs listed the correct diagnosis first in 421 of 1170 SC vignette tests (36%; 95% CI, 31-42%), among the top three results in 606 tests (52%; 95% CI, 47-59%), and among the top ten results in 681 tests (58%; 95% CI, 53-65%). SCs using artificial intelligence algorithms listed the correct diagnosis first in 46% of tests (95% CI, 40-57%), compared with 32% (95% CI, 26-38%) for other SCs. The mean rate of first correct results for individual SCs ranged between 12% and 61%. The 19 triage SCs provided correct advice for 338 of 688 vignette tests (49%; 95% CI, 44-54%). Appropriate triage advice was more frequent for emergency care (63%; 95% CI, 52-71%) and urgent care vignette tests (56%; 95% CI, 52-75%) than for non-urgent care (30%; 95% CI, 11-39%) and self-care tests (40%; 95% CI, 26-49%).
Grzeskowiak LE, Grieger JA, Andraweera P, et al.
The deleterious effects of cannabis during pregnancy on neonatal outcomes.
pp519-524. doi:10.5694/mja2.50624. PMID: 32452049.
Objectives: To evaluate whether cannabis use during pregnancy is associated with adverse neonatal outcomes that are independent of cigarette smoking.
Design: Prospective cohort study.
Setting: Adelaide (Australia), Auckland (New Zealand), Cork (Ireland), and Leeds, London and Manchester (United Kingdom).
Participants: 5610 pregnant nulliparous women with low risk pregnancies recruited for the Screening for Pregnancy Endpoints (SCOPE) study, November 2004 - February 2011. At 14-16 weeks of pregnancy, women were grouped by self-reported cannabis use.
Main outcome measures: Infant birthweight, head circumference, birth length, gestational age, and severe neonatal morbidity or mortality.
Results: 314 women (5.6%) reported using cannabis in the 3 months before or during their pregnancy; 97 (31%) stopped using it before and 157 (50%) during the first 15 weeks of pregnancy, while 60 (19%) were still using cannabis at 15 weeks. Compared with babies of mother who had never used cannabis, infants of those who still used it at 15 weeks had lower mean values for birthweight (adjusted mean difference [aMD], -127 g; 95% CI, -238 to -17 g), head circumference (aMD, -0.5 cm; 95% CI, -0.8 to -0.1 cm), birth length (aMD, -0.8 cm; 95% CI, -1.4 to -0.2 cm), and gestational age at birth (aMD, -8.1 days; 95% CI, -12.1 to -4.0 days). The differences for all outcomes except gestational age were greater for women who used cannabis more than once a week than for those who used it less frequently.
Conclusions: Continuing to use cannabis during pregnancy is an independent risk factor for poorer neonatal outcomes.
Jennings GL.
Coronavirus disease 2019 (COVID-19): angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers and cardiovascular disease.
pp502-503.e1. doi:10.5694/mja2.50622. PMID: 32441063; PMCID: PMC7280580.
Lin RJ, Lee TH, Lye DC.
From SARS to COVID-19: the Singapore journey.
pp497-502.e1. doi:10.5694/mja2.50623. PMID: 32474940; PMCID: PMC7300591.
Talley NJ.
Rapid publishing in the era of coronavirus disease 2019 (COVID-19).
pp535-536. doi:10.5694/mja2.50625. PMID: 32474933.
Lee AY, Lin MW.
Rapid publishing in the era of coronavirus disease 2019 (COVID-19).
pp535-535.e1. doi:10.5694/mja2.50617. PMID: 32474929; PMCID: PMC7300894.
Slavova-Azmanova NS, Newton JC, Saunders CM.
Marked variation in out-of-pocket costs for cancer care in Western Australia.
pp525-526. doi:10.5694/mja2.50590. PMID: 32311092.
Kistler PM, Atherton JJ, Jennings G.
Clarification of the Australian heart failure guideline recommendation for primary prevention defibrillator
implantation in non-ischaemic cardiomyopathy.
pp509-510.e1. doi:10.5694/mja2.50551. PMID: 32200548.
Saravanan L, Ormerod A.
Transfusion support in mass casualty events: lessons for hospital and pathology preparedness from the Bourke Street Mall incident.
pp504-506.e1. doi:10.5694/mja2.50611. PMID: 32447762.
Ong WL, Kang TMJ, Ratnayake G, et al.
Stereotactic radiosurgery for managing brain metastases in Victoria, 2012-2017.
pp526-527. doi:10.5694/mja2.50573. PMID: 32249431.
Worth LJ, Harrison SJ, Dickinson M, et al.
Candida auris in an Australian health care facility: importance of screening high risk patients.
pp510-511.e1. doi:10.5694/mja2.50612. PMID: 32447766.
Swannell C.
Helping infants through trauma.
C1-C2. doi:10.5694/mja2.50655. PMID: 32535951.
Dunn AG.
Will online symptom checkers improve health care in Australia?
pp512-513. doi:10.5694/mja2.50621. PMID: 32441062.
Eagar K, Westera A, Kobel C.
Australian residential aged care is understaffed.
pp507-508.e1. doi:10.5694/mja2.50615. PMID: 32474934.
New England Journal of Medicine Vol. 382 No. 23 June 4 2020
Helms J, Kremer S, Merdji H, et al.
Neurologic Features in Severe SARS-CoV-2 Infection.
pp2268-2270. doi:10.1056/NEJMc2008597. PMID: 32294339; PMCID: PMC7179967.
Zhan M, Qin Y, Xue X, et al.
Death from Covid-19 of 23 Health Care Workers in China.
pp2267-2268. doi:10.1056/NEJMc2005696. PMID: 32294342; PMCID: PMC7179960.
Keesara S, Jonas A, Schulman K.
Covid-19 and Health Care's Digital Revolution.
e82. doi:10.1056/NEJMp2005835. PMID: 32240581.
Sternberg CN, Fizazi K, Saad F, et al.
Enzalutamide and Survival in Nonmetastatic, Castration-Resistant Prostate Cancer.
pp2197-2206. doi:10.1056/NEJMoa2003892. PMID: 32469184.
Shore ND, Saad F, Cookson MS, et al.
Oral Relugolix for Androgen-Deprivation Therapy in AdvancedProstate Cancer.
pp2187-2196. doi:10.1056/NEJMoa2004325. PMID: 32469183.
Parola P, Izri A.
Bedbugs.
pp2230-2237. doi:10.1056/NEJMcp1905840. PMID: 32492304.
Minard-Colin V, Aupérin A, Pillon M, et al.
Rituximab for High-Risk, Mature B-Cell Non-Hodgkin's Lymphoma in Children.
pp2207-2219. doi:10.1056/NEJMoa1915315. PMID: 32492302.
Rubin EJ, Baden LR, Morrissey S.
Audio Interview: Diagnosis and Early Treatment of Covid-19.
e103. doi:10.1056/NEJMe2021023. PMID: 32492326.
Rourke EJ.
Waiting.
pp2184-2185. doi:10.1056/NEJMp2007073. PMID: 32283002.
Studdert DM, Zhang Y, Swanson SA, et al.
Handgun Ownership and Suicide in California.
pp2220-2229. doi:10.1056/NEJMsa1916744. PMID: 32492303.
Castelletti S.
A Shift on the Front Line.
e83. doi:10.1056/NEJMp2007028. PMID: 32272004.
Legrand M, Rossignol P.
Cardiovascular Consequences of Acute Kidney Injury.
pp2238-2247. doi:10.1056/NEJMra1916393. PMID: 32492305.
Sacks CA, Bartels SJ.
Reconsidering Risks of Gun Ownership and Suicide in Unprecedented Times.
pp2259-2260. doi:10.1056/NEJMe2007658. PMID: 32492309.
Belizán JM, Cormick G.
Milk and Health.
e86. doi:10.1056/NEJMc2005220. PMID: 32492324.
Givens DI.
Milk and Health.
e86. doi:10.1056/NEJMc2005220. PMID: 32492323.
Vanderhout S, Maguire JL.
Milk and Health.
e86. doi:10.1056/NEJMc2005220. PMID: 32492321.
Weinberg RB.
Milk and Health.
e86. doi:10.1056/NEJMc2005220. PMID: 32492322.
Astrup A.
Milk and Health.
e86. doi:10.1056/NEJMc2005220. PMID: 32492320.
Willett W, Ludwig DS.
Milk and Health. Reply.
e86. doi:10.1056/NEJMc2005220. PMID: 32492325.
Scholz M, Lam R, Turner J.
Biopsy for Prostate Cancer Diagnosis.
p2270. doi:10.1056/NEJMc2007985. PMID: 32492311.
Fraher EP, Pittman P, Frogner BK, et al.
Ensuring and Sustaining a Pandemic Workforce.
pp2181-2183. doi:10.1056/NEJMp2006376. PMID: 32268021.
Parks JM, Smith JC.
How to Discover Antiviral Drugs Quickly.
pp2261-2264. doi:10.1056/NEJMcibr2007042. PMID: 32433861.
Higano CS.
Cardiovascular Disease and Androgen Axis-Targeted Drugs for Prostate Cancer.
pp2257-2259. doi:10.1056/NEJMe2016433. PMID: 32469186.
Argenziano M, Fischkoff K, Smith CR.
Surgery Scheduling in a Crisis.
e87. doi:10.1056/NEJMc2017424. PMID: 32445439; PMCID: PMC7262972.
Yozamp N, Hornick JL, Chiodo CP, et al.
The Game Is Afoot.
pp2249-2255. doi:10.1056/NEJMcps1913599. PMID: 32492308.
Roeper M, Kummer S, Meissner T.
Treatment Threshold for Neonatal Hypoglycemia.
pp2273. doi:10.1056/NEJMc2004233. PMID: 32492316.
Thornton PS, De Leon DD, Sperling MA.
Treatment Threshold for Neonatal Hypoglycemia.
p2272. doi:10.1056/NEJMc2004233. PMID: 32492314.
Degraeuwe P.
Treatment Threshold for Neonatal Hypoglycemia.
p2272. doi:10.1056/NEJMc2004233. PMID: 32492315.
van Kempen AAMW, Boluyt N, Offringa M.
Treatment Threshold for Neonatal Hypoglycemia. Reply.
pp2273-2274. doi:10.1056/NEJMc2004233. PMID: 32492317.
Salik JR, Thomas SS.
Atrioventricular Dissociation during Ventricular Fibrillation.
e84. doi:10.1056/NEJMicm1916823. PMID: 32492307.
Stanzione A, Imbriaco M, Cuocolo R.
Biopsy for Prostate Cancer Diagnosis.
pp2270-2271. doi:10.1056/NEJMc2007985. PMID: 32492312.
Ahdoot M, Turkbey B, Pinto P.
Biopsy for Prostate Cancer Diagnosis. Reply.
p2271. doi:10.1056/NEJMc2007985. PMID: 32492313.
Vico-Alonso C, Palencia-Pérez S.
Linear IgA Bullous Dermatosis.
p2248. doi:10.1056/NEJMicm1913412. PMID: 32492306.
Naci H, Kesselheim AS.
Specialty Drugs - A Distinctly American Phenomenon.
pp2179-2181. doi:10.1056/NEJMp1909513. PMID: 32492301.
Hindié E.
Ribociclib plus Fulvestrant in Advanced Breast Cancer.
e85. doi:10.1056/NEJMc2004229. PMID: 32492318.
Slamon DJ, Jerusalem G.
Ribociclib plus Fulvestrant in Advanced Breast Cancer. Reply.
e85. doi:10.1056/NEJMc2004229. PMID: 32492319.
Anand S, Staniec A, Montez-Rath M, et al.
Using GIS Mapping to Track Hot Spots of Kidney Disease in California.
pp2265-2267. doi:10.1056/NEJMc2001023. PMID: 32492310.
Robinson JC.
Lower Prices and Greater Patient Access - Lessons from Germany's Drug-Purchasing Structure.
pp2177-2179. doi:10.1056/NEJMp2000341. PMID: 32492300.
New England Journal of Medicine Vol. 382 No. 24 June 11 2020
Grein J, Ohmagari N, Shin D, et al.
Compassionate Use of Remdesivir for Patients with Severe Covid-19.
pp2327-2336. doi:10.1056/NEJMoa2007016. PMID: 32275812; PMCID: PMC7169476.
Gudbjartsson DF, Helgason A, Jonsson H, et al.
Spread of SARS-CoV-2 in the Icelandic Population.
pp2302-2315. doi:10.1056/NEJMoa2006100. PMID: 32289214; PMCID: PMC7175425.
Goyal P, Choi JJ, Pinheiro LC, et al.
Clinical Characteristics of Covid-19 in New York City.
pp2372-2374. doi:10.1056/NEJMc2010419. PMID: 32302078; PMCID: PMC7182018.
Rome BN, Avorn J.
Drug Evaluation during the Covid-19 Pandemic.
pp2282-2284. doi:10.1056/NEJMp2009457. PMID: 32289216.
Gruber J, Sommers BD.
Paying for Medicaid - State Budgets and the Case for Expansion in the Time of Coronavirus.
pp2280-2282. doi:10.1056/NEJMp2007124. PMID: 32233337.
Tsai M, Thauland TJ, Huang AY, et al.
Disseminated Coccidioidomycosis Treated with Interferon-γ and Dupilumab.
pp2337-2343. doi:10.1056/NEJMoa2000024. PMID: 32521134.
Martins SO, Mont'Alverne F, Rebello LC, et al.
Thrombectomy for Stroke in the Public Health Care System of Brazil.
pp2316-2326. doi:10.1056/NEJMoa2000120. PMID: 32521133.
Balwani M, Sardh E, Ventura P, et al.
Phase 3 Trial of RNAi Therapeutic Givosiran for Acute Intermittent Porphyria.
pp2289-2301. doi:10.1056/NEJMoa1913147. PMID: 32521132.
Jayawardena A.
Waiting for Something Positive.
e89. doi:10.1056/NEJMp2008797. PMID: 32320555.
Bull MJ.
Down Syndrome.
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Rosenbaum L.
The Untold Toll - The Pandemic's Effects on Patients without Covid-19.
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Wakam GK, Montgomery JR, Biesterveld BE, Brown CS.
Not Dying Alone – Modern Compassionate Care in the Covid-19 Pandemic.
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Renin-Angiotensin-Aldosterone System Inhibitors in Covid-19.
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Renin-Angiotensin-Aldosterone System Inhibitors in Covid-19.
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Renin-Angiotensin-Aldosterone System Inhibitors in Covid-19.
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Between Scylla and Charybdis - Oncologic Decision Making in the Time of Covid-19.
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Renin-Angiotensin-Aldosterone System Inhibitors in Covid-19. Reply.
e92. doi:10.1056/NEJMc2013707. PMID: 32427431.
Abdool Karim SS.
The South African Response to the Pandemic.
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Rubin EJ, Baden LR, Evans M, et al.
Audio Interview: The Impact of Covid-19 on Minority Communities.
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Markewitz R, Pauli D, Wandinger KP.
The Modern Epidemic of Syphilis.
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Sato T, Shinozaki M, Tsuno NH.
The Modern Epidemic of Syphilis.
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Ghanem KG, Ram S, Rice PA.
The Modern Epidemic of Syphilis. Reply.
p2380. doi:10.1056/NEJMc2006129. PMID: 32521148.
Schwartz E.
Hormone Therapy for Postmenopausal Women.
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Hormone Therapy for Postmenopausal Women.
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Hormone Therapy for Postmenopausal Women. Reply.
e91. doi:10.1056/NEJMc2005199. PMID: 32521153.
Madan S, Mehra MR.
Microbiota and Allogeneic Hematopoietic-Cell Transplantation.
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Microbiota and Allogeneic Hematopoietic-Cell Transplantation. Reply.
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Oh JK, Tsang SH.
Stargardt Juvenile Macular Degeneration.
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Treatment of Highly Drug-Resistant Pulmonary Tuberculosis.
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Nimmo C, Naidoo K, O'Donnell M.
Treatment of Highly Drug-Resistant Pulmonary Tuberculosis.
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Conradie F, Everitt D, Crook AM.
Treatment of Highly Drug-Resistant Pulmonary Tuberculosis. Reply.
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Gonzalez-Aseguinolaza G.
Givosiran - Running RNA Interference to Fight Porphyria Attacks.
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The Vaccines for Children Program at 25 - Access, Affordability, and Sustainability.
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Esfahani K, Hudson M, Batist G.
Tofacitinib for Refractory Immune-Related Colitis from PD-1 Therapy.
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Rothstein P.
Case 5-2020: A 32-Day-Old Male Infant with a Fall.
p2381. doi:10.1056/NEJMc2004830. PMID: 32521149.
Newton AW.
Case 5-2020: A 32-Day-Old Male Infant with a Fall. Reply.
p2381. doi:10.1056/NEJMc2004830. PMID: 32521150.
Randall G, Abrahams J.
Cutaneous Colon Cancer Metastases in a Surgical Scar.
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Kazi DS, Martin LM, Litmanovich D, et al.
Case 18-2020: A 73-Year-Old Man with Hypoxemic Respiratory Failure and Cardiac Dysfunction.
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New England Journal of Medicine Vol. 382 No. 25 June 18 2020
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Observational Study of Hydroxychloroquine in Hospitalized Patients with Covid-19.
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Renin-Angiotensin-Aldosterone System Inhibitors and Risk of Covid-19.
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Mancia G, Rea F, Ludergnani M, Apolone G, Corrao G.
Renin-Angiotensin-Aldosterone System Blockers and the Risk of Covid-19.
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Akalin E, Azzi Y, Bartash R, et al.
Covid-19 and Kidney Transplantation.
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Shitara K, Bang YJ, Iwasa S, et al.
Trastuzumab Deruxtecan in Previously Treated HER2-Positive Gastric Cancer.
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Jarcho JA, Ingelfinger JR, Hamel MB, et al.
Inhibitors of the Renin-Angiotensin-Aldosterone System and Covid-19.
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Bangalore S, Sharma A, Slotwiner A, et al.
ST-Segment Elevation in Patients with Covid-19 - A Case Series.
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Clinical Characteristics of Pregnant Women with Covid-19 in Wuhan, China.
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The Urgency of Care during the Covid-19 Pandemic - Learning as We Go.
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Compassionate Use of Remdesivir in Covid-19.
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Compassionate Use of Remdesivir in Covid-19.
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Hoffmann C.
Compassionate Use of Remdesivir in Covid-19.
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Compassionate Use of Remdesivir in Covid-19.
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Compassionate Use of Remdesivir in Covid-19. Reply.
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Systematic or Test-Guided Treatment for Tuberculosis in HIV-Infected Adults.
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Audio Interview: A Look at SARS-CoV-2 Transmission.
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Reconsidering the Trade-offs of Prostate Cancer Screening.
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"We Signed Up for This!" - Student and Trainee Responses to the Covid-19 Pandemic.
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Therapy for HER2-Positive Metastatic Breast Cancer.
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Therapy for HER2-Positive Metastatic Breast Cancer. Reply.
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Fuller DH, Berglund P.
Amplifying RNA Vaccine Development.
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Empirical Antituberculosis Therapy in Advanced HIV Disease - Too Much, Too Late.
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Angioedema after t-PA Infusion.
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Detection of Structural Rearrangements in Embryos.
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The Impact of a Pass/Fail Step 1 - A Residency Program Director's View.
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A Test of Diversity - What USMLE Pass/Fail Scoring Means for Medicine.
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Objective Measures Needed - Program Directors' Perspectives on a Pass/Fail USMLE Step 1.
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Grading Changes for USMLE Step 1 - A Golden Opportunity to Recalibrate Medical Education Priorities.
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Liao R, Zhou BY, Wu ZJ.
Association between Aspirin and Hepatocellular Carcinoma.
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Association between Aspirin and Hepatocellular Carcinoma.
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Association between Aspirin and Hepatocellular Carcinoma. Reply.
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Dickey J, Phelan C.
Unrepaired Tetralogy of Fallot in Adulthood.
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A Community-Based Intervention for Hypertension in Rural South Asia.
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New England Journal of Medicine Vol. 382 No. 26 June 25 2020
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Guillain-Barré Syndrome Associated with SARS-CoV-2.
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Hospitalization and Mortality among Black Patients and White Patients with Covid-19.
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Personal Protective Equipment and Covid-19.
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Hartzband P, Groopman J.
Physician Burnout, Interrupted.
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Effects of Allopurinol on the Progression of Chronic Kidney Disease.
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Effect on Patient Safety of a Resident Physician Schedule without 24-Hour Shifts.
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Hydroxyurea Dose Escalation for Sickle Cell Anemia in Sub-Saharan Africa.
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Serum Urate Lowering with Allopurinol and Kidney Function in Type 1 Diabetes.
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Palmer BF, Clegg DJ.
Salicylate Toxicity.
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King JS.
Covid-19 and the Need for Health Care Reform.
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Rubin EJ, Baden LR, Morrissey S.
Audio Interview: The Challenges of Safe Reopening.
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Talish M, DiLorenzo AM.
Uremic Stomatitis.
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Feig DI.
Urate-Lowering Therapy and Chronic Kidney Disease Progression.
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Larvie M, Lev MH, Hess CP.
More on Neurologic Features in Severe SARS-CoV-2 Infection.
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More on Neurologic Features in Severe SARS-CoV-2 Infection.
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Ingelfinger JR.
Kinder, Gentler Dementia-Friendly Alzheimer's Care.
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Cetin B, Gumusay O.
Pembrolizumab for Early Triple-Negative Breast Cancer.
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Schmid P, Dent R, O'Shaughnessy J.
Pembrolizumab for Early Triple-Negative Breast Cancer. Reply.
e108. doi:10.1056/NEJMc2006684. PMID: 32579835.
Nolen L.
How Medical Education Is Missing the Bull's-eye.
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Das SK, Choupoo NS, Ray S.
Oxygen Therapy in the ICU.
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Albert TJ, Swenson ER.
Oxygen Therapy in the ICU.
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Cheung JCH, Lam PKN.
Oxygen Therapy in the ICU.
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Young P, Mackle D, Bellomo R.
Oxygen Therapy in the ICU. Reply.
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Oxygen Therapy in the ICU. Reply.
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Oxygen Therapy in the ICU. Reply.
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Gaieski DF.
Targeted Temperature Management for Cardiac Arrest.
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Deye N, Voicu S, Megarbane B.
Targeted Temperature Management for Cardiac Arrest.
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Moskowitz A, Berg KM, Donnino MW.
Targeted Temperature Management for Cardiac Arrest.
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van der Jagt M.
Targeted Temperature Management for Cardiac Arrest.
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Targeted Temperature Management for Cardiac Arrest.
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Targeted Temperature Management for Cardiac Arrest. Reply.
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Kirk B, Salech F, Duque G.
Fall Prevention in Community-Dwelling Older Adults.
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Jones KL, Morley JE, Horowitz M.
Fall Prevention in Community-Dwelling Older Adults.
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McCrum C.
Fall Prevention in Community-Dwelling Older Adults.
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Andréasson K, Hesselstrand R.
Fall Prevention in Community-Dwelling Older Adults.
p2580. doi:10.1056/NEJMc2005662. PMID: 32579828.
Ganz DA, Latham NK.
Fall Prevention in Community-Dwelling Older Adults. Reply.
pp2581-2582. doi:10.1056/NEJMc2005662. PMID: 32579831.
Hung WY, Huang CY.
Mesenteric Volvulus from Jejunal Diverticulosis.
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Frye BC, Meiss F, von Bubnoff D, et al.
Vasoactive Intestinal Peptide in Checkpoint Inhibitor-Induced Pneumonitis.
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Wu K, Hirsch LJ, Babl FE, et al.
Choosing Anticonvulsant Medications to Manage Status Epilepticus.
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Prevention of Early Ventilator-Associated Pneumonia.
p2582. doi:10.1056/NEJMx200010. Erratum PMID: 32584532.
De Bels D, Honore PM, Redant S.
Nonsedation or Light Sedation in Critically Ill, Mechanically Ventilated Patients.
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Olsen HT, Nedergaard HK, Toft P.
Nonsedation or Light Sedation in Critically Ill, Mechanically Ventilated Patients. Reply.
e107. doi:10.1056/NEJMc2011055. PMID: 32579833.
Gartland MG, Hidalgo JA, Danaher FS.
Case 20-2020: A 7-Year-Old Girl with Severe Psychological Distress after Family Separation.
pp2557-2565. doi:10.1056/NEJMcpc2002413. PMID: 32579817.
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