Scleroderma and Myositis

20% of limited scleroderma patients have anti-Scl-70. Anti-centromere antibody occurs in 80% to 90% of patients with limited scleroderma. 10% to 15% of patients with diffuse PSS have anti-centromere. The presence of anti-Scl-70 predicts a worse prognosis. Serology ................
................