Valerie Horsley



Valerie Horsley

Associate Professor

Departments of Molecular, Cellular and Developmental Biology

and Dermatology

Yale University 

Kline Biology Tower--Room 226

219 Prospect Street

New Haven, CT 06520-8103

203-436-9126

valerie.horsley@yale.edu 

horsley.yale.edu/

Education and Work Experience

1994-1998 B.S. in Biology, Furman University, Greenville, SC

1998-2003 Ph.D. in Biochemistry, Cell and Dev. Biol., Emory University, Atlanta, GA

Advisor: Grace Pavlath (thesis project: Cell fusion during mammalian myogenesis)

2003-2008 Postdoctoral Fellow, Rockefeller University, NY, NY

Advisor: Dr. Elaine Fuchs (Mechanisms of stem cell lineage commitment/quiescence)

2009-2011 Assistant Professor, Yale University, Dept. of Molecular, Cellular and

Developmental Biology

2011-2014 Maxine F. Singer ’57 Assistant Professor

2011-2014 Assistant Professor, Yale University, Dept. of Dermatology

2014- Associate Professor, Yale University, Dept. of Molecular, Cellular and Developmental Biology (Primary Appointment) and Dermatology (Secondary Appointment)

Honors and Awards

1998 Elected to Phi Beta Kappa

2000-2002 NIH Training Grant in Biochemistry, Cell and Molecular Biology

2001-2003 Achievement Reward for College Scientists (ARCS) scholar

2003-2004 Rockefeller University Women and Science Fellowship

2004-2006 Damon Runyon Cancer Research Foundation Fellowship

2006 Robert Black Fellow of the Damon Runyon Cancer Research Foundation

2007 K99/R00 Pathway to Independence Award

2009 Blavatnick Award, NY Academy of Sciences

2010 Pew Scholar Award

2011 Maxine F. Singer ’57 Endowed Assistant Professor

* Presented to the top female junior faculty member in the life sciences at Yale

2012 Presidential Early Career Award (PECASE)

2012 Rosalind Franklin Young Investigator Award, Genetics Society of America

2013 F1000 Faculty of the Year, Developmental Biology

2017 Montagna Lecture Award, Society of Investigative Dermatology

Publications

Research Articles

1. B.B. Friday, V. Horsley, and G.K. Pavlath. (2000). Calcineurin is required for the initiation of skeletal muscle differentiation. J. Cell Biol. 149: 657-665.

2. V. Horsley, B.B. Friday, S. Matteson, K.M. Kegley, J. Gephart, and G.K. Pavlath. (2001). Regulation of the growth of multinucleated muscle cells by an NFATC2-dependent pathway. J. Cell Biol. 53: 329-38.

3. V. Horsley and G.K. Pavlath. (2003). Prostaglandin F2( induces skeletal muscle growth via an NFATC2 dependent pathway. J. Cell Biol. 161: 111-118.

4. V. Horsley, K. Jansen, S.T. Mills, and G.K. Pavlath. (2003). IL-4 acts as a myoblast recruitment factor during mammalian muscle growth. Cell. 113: 483-94.

* Preview: Fusion with the fused: a new role for interleukin-4 in the building of muscle. Cell, 113: 422-423.

5. V. Horsley, D. O’Carroll, R. Tooze, Y. Ohinata, M.Saitou, T. Obukhanych, M. Nussenzweig, A. Tarakhovsky and E. Fuchs. (2006). Blimp1 defines a novel progenitor population that governs cellular input to the sebaceous gland. Cell. 126: 597-609.

6. V. Horsley, A. O. Aliprantis, L. Polak, L.H. Glimcher and E. Fuchs. (2008). NFATc1 balances quiescence and proliferation of skin stem cells. Cell. 132: 299-310.

*Preview: A new role for an old friend: NFAT and stem cell quiescence. Cell Stem Cell. 2: 104-106.

*Feature: Faculty of 1000.

7. E. Festa, J. Fretz, R. Berry, B. Schmidt, M. Rodeheffer, M. Horowitz and V. Horsley. (2011). Adipocyte lineage cells contribute to the skin stem cell niche. Cell. 146: 761-771.

*Preview: Niche crosstalk: intercellular signals at the hair follicle. Cell. 146: 678-81.

*Feature: Faculty of 1000.

8. A. F. Mertz, S. Banerjee, Y. Che, G. K. German, Y. Xu, C. Hyland, M. C. Marchetti, V. Horsley, and E. R. Dufresne (2012). Scaling of Traction Forces with the Size of Cohesive Cell Colonies. Phys. Rev. Lett. 108: 198101.

9. H. McGee, C. Booth, E.Festa, R. Flavell, and V. Horsley. (2012). Interleukin-22 mediates acute skin wound healing by promoting fibroblast function. J. Invest. Dermatol. 133: 1321-9.

10. A. F. Mertz, Y. Che, S. Banerjee, J. Goldstein, S. Revilla, C. Niessen, M. C. Marchetti, E. R. Dufresne and V. Horsley (2013). Cadherin-based intercellular adhesions organize epithelial cell-matrix forces. PNAS. 110: 842-7.

*Feature: Faculty of 1000

11. B. Schmidt and V. Horsley. (2013). Intradermal adipocytes regulate fibroblast recruitment during skin wound healing. Development. 140: 1517-27.

*Preview: Adipocytes and Wound Healing. Development 2013 140:e703.

12. A. Tadeu and V. Horsley. (2013). Notch signaling represses p63 expression in the developing surface ectoderm. Development. 140: 3777-3786.

13. J. Goldstein, S. Fletcher, E. Roth, C. Wu, A. Chun, and V. Horsley. (2014). Calcineurin/Nfatc1 signaling controls skin stem cell quiescence through systemic hormone regulation by prolactin. Gene. Dev. 28: 983-994.

*Feature: Faculty of 1000

14. P. Sun, M. Fallahi, K. Watanabe, B. Lee, C. Rheaume, D. Wu, V. Horsley, and X. Dai. (2014). Pygo2 regulates β-catenin-induced hair follicle stem cell/progenitor cell activation and skin hyperplasia. PNAS. 111: 10215-20. PMID: 24982158.

15. E. Jeffery, R. Berry, C. D. Church, S. Yu, B. A. Shook, V. Horsley, E. D. Rosen and M. Rodeheffer. (2014) Characterization of Cre Recombinase Models for the study of Adipose Tissue. Adipocyte. 3: 206-11.

16. A. Tadeu, S. Lin, L. Hou, L. Chung, M. Zhong, H. Zhoa and V. Horsley. (2015) Transcriptional profiling of keratinocyte specification in human embryonic stem cells. Plos One. 10: e0122493.

17. R. Stewart, A. Zubek, K. Rosowski, S. Schreiner, V. Horsley*, and M. King* (*co-corresponding author). (2015) LINC complexes support hair follicle integrity and intercellular adhesion. J. Cell Biol. 209: 403-18.

*Preview: SUN protection for the skin. 209(3): 319.

18. K. Rosowski, A. Mertz, S. Norcross, E. Dufresne, and V. Horsley. (2015) Edges of human embryonic stem cell colonies display distinct mechanical properties and differentiation potential. Sci. Rep. 5: 14218.

19. J. Goldstein, E. Roth, N. Roberts, R. Zwick, S. Lin, S. Fletcher, A. Tadeu, C. Wu, A. Beck, C. Zeiss, M. Suarez-Farinas and V. Horsley. (2015) Loss of endogenous Nfatc1 reduces the rate of DMBA/TPA-induced skin tumorigenesis. Mol. Biol. Cell. pii: mbc.E15-05-0282.

20. B.A. Shook, E. Xiao, Y. Kumamoto, A. Iwasaki, and V. Horsley. (2016) CD301b+ monocyte /macrophage-derived cells are essential for effective skin wound healing. JID. 136(9): 1885–1891.

21. G. C. Rivera-Gonzalez, B.A. Shook, B. Holtrup, K. Bollag, M. S. Rodeheffer and V. Horsley. (2016) Adipocyte stem cell self-renewal is regulated by a Pdgfa/Akt signalling axis in the skin. Cell Stem Cell. 19(6): 738-751.

22. N. Roberts, B. Adams, N. I. McCarthy, R. M. Tooze, S. M. Parnell, G. Anderson, S. M. Kaech, and V. Horsley. (2017) Prdm1 regulates thymic epithelial function to prevent

autoimmunity. JI. 199(4): 1250-1260.

23. R.K. Zwick, M.C. Rudolph, B.A. Shook, B. Holtrup, E. Roth, V. Lei, A. Van Keymeulen, V. Seewaldt, S. Kwei, J. Wysolmerski, M.S. Rodeheffer & V. Horsley. (2018). Adipocyte hypertrophy and lipid dynamics underlie mammary gland remodeling after lactation. Nature Comm. 9, 3592.

24. B.A. Shook, R. R. Wasko, G. C. Rivera Gonzalez, E. Salazar-Gatzimas, F. López-Giráldez, B. C. Dash, A. R. Muñoz-Rojas, K. D. Aultman, R. K. Zwick, V. Lei, J. L. Arbiser, K. Miller-Jensen, D. A. Clark, H. C. Hsia, V. Horsley. (2018). Myofibroblast proliferation and heterogeneity is supported by macrophages during skin repair. Science. In press.

Reviews and Invited Chapters

1. V. Horsley and G.K. Pavlath. (2002). NFAT proteins: Ubiquitous regulators of cell differentiation and adaptation. J. Cell Biol. 156: 771-4.

2. G.K. Pavlath and V. Horsley. (2003). Cell fusion in skeletal muscle: Central role of NFATC2 in regulating muscle cell size. Cell Cycle. 2: 420-423.

3. V. Horsley and G.K. Pavlath. (2004). Making a Multinucleated Cell: Molecules that Regulate Myoblast Fusion. Cells, Tissues, and Organs. 176: 67-78.

4. C. Blanpain, V. Horsley, and E. Fuchs. (2007). Epithelial Stem Cells: Turning over New Leaves. Cell. 128: 445-458.

5. V. Horsley and E. Fuchs. (2007). Reprogramming somatic cells to their embryonic state. HSFP Journal. 1: 89-93.

6. E. Fuchs and V. Horsley. (2008). More than one way to skin... Gene. Dev. 22: 976-985.

7. E. Fuchs and V. Horsley. (2011). Ferreting stem cells out of their niches. Nature Cell Biology. 13: 513-8.

8. V. Horsley. (2011). Upward bound: Follicular stem cell fate decisions. EMBO J. 30: 2986-7.

9. J. Goldstein and V. Horsley. (2012). Home sweet home: Skin stem cell niches. Cell. Mol. Life Sci. 69: 2573-82.

10. B. Schmidt and V. Horsley. (2012). Unraveling adipocyte-hair follicle communication. Exp. Dermatol. 21: 827-30.

11. V. Horsley. (2012). Split decisions: oesophageal progenitor cell behaviour. EMBO J. 31: 3653-4.

12. C. Niemann and V. Horsley. (2012). Development and homeostasis of the sebaceous gland. Semin. Cell Dev. Biol. 23: 928-36.

13. G. Rivera, B. Shook and V. Horsley (2014). Adipocytes in Skin Health and Disease. Cold Spring Harb. Perspect. Med. 4. pii: a015271.

14. A. Tadeu and V. Horsley. (2014). Epithelial Stem Cells in Adult Skin. Curr. Top. Dev. Biol. 107: 109-31.

15. R. Driskell, C.A.B. Jahoda, C. Chuong, F. Watt, and V. Horsley. (2014). Defining Dermal Adipose Tissue. Exp. Dermatol. 23: 629-31.

16. N. Roberts and V. Horsley. (2014). Developing stratified epithelia: lessons from the epidermis and thymus. Wiley Interdiscip. Rev. Dev. Biol. 3: 389-402.

17. S. Ebmeier and V. Horsley. (2015). Origin of Fibrosing Cells in Systemic Sclerosis. Curr. Opin. Rheumatol. 27: 555-62.

18. C.M. Alexander, I. Kasza, C.E. Yen, S.B. Reeder, D. Hernando, R.L. Gallo, C.A. Jahoda, V. Horsley, O.A. MacDougald. (2015). Dermal White Adipose Tissue: A New Compartment of the Thermogenic Response. J. Lipid Res. pii: jlr.R062893.

19. B.A. Shook, G. C. Rivera Gonzalez, S. Ebmeier, G. Grisotti, R. K. Zwick, V. V. Horsley. (2016). The Role of Adipocytes in Tissue Regeneration and Stem Cell Niches. Annual Review of Cell and Dev. Bio.. 32: 609-631.

20. V. Horsley and F. Watt. (2017). Repeal and Replace: Adipocyte Regeneration in Wound Repair. Cell Stem Cell. 20(4): 424-426.

21. V. Horsley and S. Naik. (2017). Tregs Expand the Skin Stem Cell Niche. Dev. Cell. 41(5): 455-456.

22. R. K. Zwick, C.F. Guerrero-Jaurez, V. Horsley, and M. Plikus. (2018). Anatomical, Physiological, and Functional Diversity of Adipose Tissue. Cell Metab. 27(1): 68-83.

Research Support

Pending

Source: NIH

Title: Mechanical Regulation of Epidermal Homeostasis

Proposed dates: 04/01/19-03/31/24

Role: Co-PI (with Megan King)

Source: NIH R01

Title: Role of Adipocytes in Skin Wound Healing

Proposed Dates: 04/01/19-03/31/24

Role: PI

Current

Source: NIH R01 AR069550

Title: Mechanisms that regulate skin wound healing

Proposed dates: 04/01/16-03/31/21

Role: PI

Source: Amway Inc.

Gift to support our research

Dates: 1/01/17-12/31/17

Role: PI

Completed

Source: CT Innovations CSCRF 12-SCB-YALE-01

Title: Generation of functional keratinocytes from hESCs

Dates: 10/01/2012 — 09/30/2016

Role: PI

Source: Scleroderma Foundation

Title: Functional analysis of the role of adipocytes in skin fibrosis

Dates: 04/01/16-3/31/18

Role: PI

Source: NIH R01 AR060295

Title: Extrinsic Regulation of Epidermal Homeostasis

Dates: 09/30/2011 – 08/31/2017

Role: PI

Source: Gruber Foundation/Rosalind Franklin Young Investigator Award

Dates: 10/01/2013 — 12/31/2015

Role: PI

Source: NIH P30AG021342; Pilot and Exploratory Studies Core of the Yale Claude D. Pepper Center Older Americans Independence Center

Title: The role of dermal adipocytes in dysfunction of aged skin

Dates: 07/01/2015 — 06/30/2016

Role: PI

Source: Unilever

Title: Examining adipocytes in human skin

Dates: 7/01/2014 — 6/30/2015

Role: PI

Source: Schick

Title: Determining how shaving influences inflammation

Dates: 7/01/2014 — 6/30/2015

Role: PI

Source: NIH R00AR054775

Title: Mechanisms of sebaceous gland development

Dates: 04/01/2009 — 03/30/2011

Role: PI

Source: CT Innovations CSCRF

Title: Transcriptional Control of Keratinocyte Differentiation in Human ES Cells

Dates: 6/01/2009 — 05/31/2011

Role: PI

Source: Pew Charitable Trusts

Title: Transcriptional Regulation of Tissue Development and Homeostasis

Dates: 07/01/2010 — 06/30/2015

Role: PI

Source: CT Innovations CSCRF (12-SCA-YALE-02)

Title: Mechanical factors influencing the differentiation of human embryonic stem cells

Dates: 10/15/2012 — 10/14/2014

Role: co-PI (with E. Dufresne)

Public Presentations

2018

Seminars

Tufts University (4/24/18)

Washington University, St. Louis (5/31/2018)

Washington State University (8/16/2018)

University Colorado Boulder (9/20/2018)

Boston University (10/2/2018)

Conferences

International Society for Investigative Dermatology, Invited Speaker (5/18/2017)

International Society for Stem Cell Research, Invited Speaker (6/21/2018)

Gordon Research Conference, Tissue Niches & Resident Stem Cells in Adult Epithelia, Invited Speaker and co-Chair (8/23/16)

2017

Seminars

Georgetown University (12/17/17)

Conferences

Scleroderma Research Foundation Conference, Invited Speaker (2/18/2017)

Gordon Research Conference, “Epithelial Keratinization and Differentiation”, Invited Speaker (5/10/2017)

American Hair Research Society, Invited Speaker (5/17/2017)

NIH, Adipose Tissue Workshop, Invited Speaker and co-Organizer (5/23/2017)

New York Stem Cell Foundation, Invited Speaker (10/2017)

Gordon Research Conference, Tissue Repair and Regeneration, Invited Speaker (6/8/2017)

2016

Seminars

University of Colorado Denver (1/4/16)

University of California Irvine (5/19/16)

Conferences

Society for Investigative Dermatology, Invited Speaker (5/12/2016)

Gordon Research Conference, Signaling by Adhesion Receptors, Invited Speaker (6/21/16)

Gordon Research Conference, Tissue Niches & Resident Stem Cells in Adult Epithelia, Invited Speaker (8/9/16)

Horizons in Molecular Biology Symposium, Invited Speaker (9/13/16)

Beckman Research Institute of City of Hope Symposium, Invited Speaker (11/16)

NIDDK sponsored workshop: “Adipose Tissue Niche:  Role in Health and Disease”, Co-organizer and Invited Speaker (11/16)

2015

Seminars

Columbia University (1/14/15)

University of Pennsylvania (2/5/15)

Wesleyan University (4/30/15)

Northwestern University (9/9/15)

University of Cologne (10/28/15)

Yale University, Endrocrinology Program (11/15)

Yale University, Immunobiology Department (12/15)

Conferences

Skin Biology Symposium, Rockefeller University, Organizer and Invited Speaker (5/4/2015)

Society for Investigative Dermatology, Blank Forum, Invited Speaker (5/7/2015)

Gordon Research Conference, “Mammary Gland Biology”, Invited Speaker (6/10/2015)

Gordon Research Conference, “Epithelial Keratinization and Differentiation”, Invited Speaker (7/15/2015)

International Society of Hair Restoration Surgery Annual Meeting, Featured Guest Speaker (9/10/2015)

Basel-Manchester Forum, Skin Repair & Regenerative Plastic Surgery, Keynote Speaker (10/30/15)

Montagna Symposium of Skin Biology, Organizer and Invited Speaker (10/2015)

National American Hair Society Meeting, Session Director and Invited Speaker (12/2015)

2014

Seminars

HudsonAlpha Institute for Biotechnology (3/19/14)

Emory University (4/15/14)

University of California San Diego (6/14/14)

Clemson University (10/23/14)

Furman University (10/24/14)

Conferences

CURE/BIOHAVEN Conference, Speaker/Panelist (10/21/14)

CT Stem Cell Retreat, Invited Speaker

NextGen Stem Cell Meeting, Invited Speaker (5/7/15)

Society of Investigative Dermatology, Invited Speaker (5/15)

Abbvie-Immunobiology conference, Invited Speaker (12/3/14)

2013

Seminars

Duke University, Developmental & Stem Cell Biology Colloquium (1/16/2013)

Yale University, Dermatology Department

University of Cincinnati Children’s Hospital (9/4/13)

Cornell University (9/27/13)

Albert Einstein (10/14/13)

Yale University, Vascular Biology Program (11/11/13)

Rutgers Dermatology Symposium (11/16/13)

Unilever Science Expo (12/11/13)

Yale University, Cardiology Department (12/15/13)

Conferences

Gordon Research Conference, “Epithelial Differentiation and Keratinization”, Invited Speaker (5/14/13)

Gordon Research Seminar, “Epithelial Differentiation and Keratinization”, Invited Speaker (5/12/13)

Keystone Symposium “Stem Cell Regulation in Homeostasis and Disease”, Invited Speaker (2/26/13)

2012

Seminars

University of British Columbia, Biomedical Research Centre (4/13/12)

Yale University, Dermatology Department (4/4/12)

University of Georgia, Developmental Biology Symposium Speaker (10/12/12)

Cambridge-Yale Symposium on Stem Cells (9/10/12)

University of Dundee (9/12/12)

John Hopkins University, Department of Biochemistry, School of Public Health (12/3/12)

Conferences

Dermatogenetics, Invited Speaker (2/10/12)

Society of Investigative Dermatology, PhD retreat, Keynote Speaker (5/9/12)

2011

Seminars

Emory University, Chemical Biology Department (2/21/11)

STEMCONN biannual meeting (3/22/11)

Conferences

International Society for Stem Cell Research Annual Meeting, Speaker and Session Chair (6/16/11)

Society for Investigative Dermatology Annual Meeting, State-of-the-Art Lecture and Session Chair (5/5/11)

Gordon Research Conference, “Epithelial Differentiation and Keratinization”, Invited Speaker (7/4/11)

2010

Seminars

Columbia University, Biology Department (2/2010)

Stanford University, Department of Developmental Biology (6/14/10)

Mt. Sinai, Department of Developmental Biology (9/30/10)

Yale Stem Cell Retreat (10/22/10)

University of Connecticut, School of Pharmacy (10/25/10)

University of Iowa, Department of Molecular Physiology & Biophysics (11/10/10)

Conferences

Connecticut Stem Cell Meeting, Invited Speaker (1/29/10)

Keystone Symposia, “Stem Cell Differentiation and Dedifferentiation”, Invited Speaker (2/18/10)

Society for Investigative Dermatology Annual Meeting, Speaker and Session Chair (5/6/10)

International Society for Stem Cell Research, Annual Meeting, Invited Speaker (6/17/10)

2009

Seminars

Mt Sinai, Department of Oncological Sciences (4/09)

Conferences

National Hair Research Society, Featured Speaker (5/8/09)

2008

Seminars

University of Michigan, Center for Stem Cell Research and Department of Dermatology

Harvard University, Department of Stem Cell and Regenerative Medicine, Harvard Stem Cell Center

Yale University, Department of Molecular, Cellular and Developmental Biology, Yale Stem Cell Center

University of Pennsylvania, Cell and Developmental Biology

2007.

Seminars

New York Skin Biology Club, New York, NY

MGH Center for Regenerative Medicine, Harvard Stem Cell Institute

University of Texas Southwestern, Department of Cell Biology

Columbia University, Department of Genetics and Development

John Hopkins, Molecular Biology and Genetics

Conferences

Epithelial Stem Cell Workshop, Beatson Cancer Research Institute, Glasgow, Scotland, Invited Speaker

Teaching

Undergraduate Courses

2009-2014 Lecturer, MCDB205, “Cell Biology”

2014-present Lecturer, BIOL102, “Foundations in Cell Biology”

Undergraduate Seminar Courses

2010-present Mentor, MCDB495, “Senior Research”

2010-2011 Session Leader, MCDB495, “Senior Research”

Graduate Courses

2011-2014 Course Director, MCDB901/GENE901/CBIO901, “Ethics in Science”

2010-2014 Founding Course Director, MCDB902/3, “Graduate Seminar Course”

2010-2011 Lecturer, MB&B520, “Boot Camp Biology”

2010 Instructor, MCDB900, “How to Write a Scientific Manuscript”

2013-2015 Instructor, “Responsible Conduct in Research Course”

2015 Instructor, Cell Biology, Shanghai Tech, Shanghai China

2016-present Instructor, MCDB602, “Molecular Cell Biology”

2016-present Instructor, MCDB603, “Seminar in Molecular Cell Biology”

2016-present Course Director, MCDB900, “1st year introduction to graduate school”

Outreach

2009-present “Science Experiments” –Children ages 4-9

I go to each of my daughter’s classrooms annually and do a presentation on science on topics ranging from matter to cell biology.

Mentoring at Yale University

Junior Faculty Mentoring

Shirin Bahmanyar (formal). Murat Acar, Damon Clark and Joshua Gendron (informal).

Undergraduate Research Mentoring

2009-2011 Alexandra Graham, Summer Research, Senior Thesis

2009 Rachel O’Keefe, Summer Research

2010-2011 Sage Aronson, Summer Research

2010-2013 Yonglu Che, Summer and Annual Research

2010 Sarah Ballatori, Summer Research

2010 Martha Getachew, STARS program, Summer Research

2011-2014 Sean Fletcher, STARS program, Annual Research, Senior Thesis

2012 Stephen Revilla, Sackler Summer program

2012 Andrew Chun, Summer Research

2013 Sam Norcross, Sackler Summer program

2013-2015 Kevin Hochstrasser, Summer Research, Senior Thesis

2013 Adrian Fortin, Summer Research

2013-present Eve Roth, Summer and Annual Research

2013-2015 Erin Song, Summer and Annual Research, Senior Thesis

2013 Christine Wu, Summer Research

2014-present Christina Kim, STARS program, Summer Research

2014 Amanda Farrell, STARS program, Summer and Annual Research

2014 Mary Yates, Sackler Summer program

2015-present Stephen Le Breton, Summer and Annual Research

2015-2016 Bertie Geng, Summer and Annual Research

2015-2016 Katie Bollag, Summer and Annual Research

Graduate Research Mentoring in My Laboratory (Current position)

2010-2011 Heather McGee, MD/PhD* (Resident at UCSF)

co-mentored with Richard Flavell

2010-2013 Aaron Mertz (Postdoctoral Fellow with Elaine Fuchs)

co-mentored with Eric Dufresne

2010-2014 Jill Goldstein (Postdoctoral fellow with Amy Wagers)

2011-2014 Barbara Schmidt (Editor with Genome Sciences)

2011-2015 Kathryn Rosowski (Postdoctoral Fellow)

2012-present Rachel Zwick

2014-present Gabriella Grisotti

2014-2016 Sarah Ebmeier

PhD Student Thesis Committees (Year Degree Awarded; Affiliation)

* indicates served on PhD Qualifying Exam

Sophia Gayle* 2013 Yale, Genetics

Barbara Hirschman* 2013 Yale, Immunobiology

Callen Hyland* 2013 Yale, MCDB

Chanatip Metheetrairut* 2014 Yale, MCDB

Su-Yi Tsai 2011 Mt. Sinai, Developmental Biology

Devin Noblin* 2014 Yale, MCDB

Ryan Berry* 2014 Yale, MCDB

Minlee Kim* 2015 Yale, MCDB

Jacob Musser* 2015 Yale, EE&B

Rachel Sennett 2015 Mt. Sinai, Developmental Biology

Rostislav Boltyanskiy 2015 Yale, Physics

Patrick McMillen 2015 Yale, MCDB

Victor Wong* 2016 Yale, MCDB

Jonathan Levinsohn* current student Yale, Genetics

Liz Min current student Yale, Cell Biology

Jemilat Salami * current student Yale, MCDB

Maggie Sledd* current student Yale, Cell Biology

Young Lim* current student Yale, Genetics

Carly Cox current student Yale, MCDB

Young Kim current student Yale, Genetics

Postdoctoral Fellow Mentoring (Current position)

2009-2014 Ana Tadeu, PhD (Medical Writer; Porterhouse Medical, UK)

2011-2015 Natalie Roberts, PhD (Postdoctoral Fellow, Hayday Laboratory, UK)

2013-2015 Amanda Zubek, MD/PhD (Postdoctoral Fellow, Yale Dermatology)

2012-2017 Guillermo Rivera, PhD

2012-present Brett Shook, PhD

2013-2015 Samantha Lin, PhD (Lecturer, Yale MCDB Department)

Honors Awarded to Trainees

2011 Fundação para a Ciência e Tecnologia Postdoctoral Award (Ana Tadeu)

2014 Dermatology Foundation Research Fellowship (Amanda Zubek)

2014 Lo Family Fellowship (Rachel Zwick)

2014 F31 NRSA NICHD (Rachel Zwick)

2015 New York Stem Cell Foundation Fellowship (Brett Shook)

2015 American College of Surgeons Fellowship (Gabriella Grisotti)

2015 Dermatology Foundation Career Development Award (Amanda Zubek)

2018 Pew Fellowship (Nanda Forni)

Activities and Service to Scientific Community

Consulting

2010-2014 Schick Hair follicle growth

2013-2016 Unilever Skin function

Professional Societies

International Society for Stem Cell Research

Society for Investigative Dermatology

National Service

2010 Board of Scientific Counselors--Intramural Program of the National Institute of Arthritis and Musculoskeletal and Cutaneous Diseases

2012 National Institutes of Health Grant Reviewer, Arthritis, Connective Tissue and Skin study section (June), ad hoc

2013-present New York Stem Cell Foundation Postdoctoral Fellowship Reviewer

2013 National Institutes of Health Grant Reviewer, Arthritis and Musculoskeletal and Skin Diseases Special Grants Review Committee (June), ad hoc

2013-present International Society for Stem Cell Research Audit Committee

2014 National Institutes of Health Grant Reviewer, Musculoskeletal, Oral and Skin Sciences study section (July), ad hoc

2012-2014 Society of Investigative Dermatology, Education Committee

2015-2016 Society of Investigative Dermatology, Education Committee, Co-Chair

2015 National Institutes of Health Grant Reviewer, Intercellular Interactions study section (February), ad hoc

2016-present Editor, eLife

2016-present National Institutes of Health Grant Reviewer, Arthritis, Connective Tissue and Skin study section, permanent member

2016-present National Hair Research Society Board Member

2017-present Medical and Scientific Review Committee, Dermatology Foundation

Journal Reviewer (ad hoc reviewer)

Development; Developmental Biology; EMBO Journal; Journal of Cell Biology; Journal of Investigative Dermatology; Molecular and Cellular Biology; Nature; Nature Cell Biology; Nature communications; Proceedings of the National Academy of Sciences; Cell Stem Cell; Cell Reports; Elife, Science.

Service at Yale

Yale University Service

2009-2014 Founding Organizer, FAS Junior Faculty Group

I established a group at Yale that initially included all of Science Jr. Faculty but eventually all of Yale. We met monthly to discuss topics of interest including mentoring, tenure and promotion, and strategies for success in teaching.

2009 Organizer, Yale Stem Cell Center Retreat Committee

2010-2011 Member, MCDG Graduate Admissions Committee

2011-present Member, Yale Stem Cell Center Advisory Committee

2010 Organizer, Yale University Childcare Initiative

Megan King and I met with Stephanie Spangler and Francis Rosenbluth regularly to discuss expansion of childcare resources at Yale: resulted in establishment of The Nest at Yale for children ages 1-3 with a priority for Women Faculty in Science.

2011 Member, Yale University Childcare Task Force

2012 Organizer, Yale Jr. Faculty Retreat

2012-present Member, Lo Family Fellowship Selection Committee

2013-present Member, Women’s Faculty Forum Steering Committee

2013 Yale College Executive Committee

2013-2015 Advisory Committee for Postdoctoral Affairs

2013 Discussion regarding facilities and Yale’s vision for STEM at Yale with President Salovey and Provost Polak

2014 FAS Senate Implementation Committee

* One of two untenured ladder faculty on this committee, which established the format and rules for the inaugural senate for Yale University faculty in the Arts and Sciences.

2015 FAS Senate Election Committee, Co-Chair

This committee implemented an electronic voting system for the election of the first 22 senators for the inaugural senate for Yale University faculty in the Arts and Sciences using the single transferable voting system.

2013-present Yale Biology Building (YBB) Building Committee Member

• YBB Committee serves as the faculty advisory body for the design and construction of the ~$250 M Yale Biology Building to be completed in 2019.

2016-2017 Member, Institutional Animal Care and Use Committee (IACUC)

2017-2018 Vice Chair, Institutional Animal Care and Use Committee (IACUC)

2016-present Member, Graduate School of Arts and Sciences Climate and Inclusion Committee

2016-present Member, Cancer Biology Institute Advisory Committee

MCDB Department Service

2009-present Member, MCDB Seminar Committee

2009-2010 Organizer, Developmental Biology Training Grant Symposium

2009-2011 Chair, MCDB Retreat Committee

2010-present Chair, MCDB Animal Committee

2010-2014 Member, MCDB Graduate Affairs Committee

2011-present Founding Director, Science Hill Flow Cytometry Facility

I was awarded an equipment grant from the NIH (official PI was Weimin Zhong due to my lack of R01) that established a Flow cytometry facility on Science Hill.

2013-2016 Chair, MCDB Communications Committee

I completely revamped the MCDB website and updated the news and content regularly.

2013-2015 Founding Organizer, MCDB Women in Science group

I established a group in MCDB for women faculty and graduate students to build community and provide a forum for discussing issues related to gender and science.

2016-present Director of Graduate Admissions (DGA)

2016-present Co-Director of Molecular, Genetics and Development Track of Graduate Program in Biological and Biomedical Science

2016-2017 Chair, MCDB Professional Climate and Diversity Committee

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