Medicine.umich.edu



Eric Stephen White, MDProfessor of MedicineDivision of Pulmonary and Critical Care Medicine3916 TC SPC 53601500 E. Medical Center DriveAnn Arbor, MI 48109-5642(734) 647-6477(734) 936-5048 (fax)docew@umich.edu TOC \o "1-3" \h \z \u Education and Training PAGEREF _Toc405816880 \h 2Certification and Licensure PAGEREF _Toc405816881 \h 2Academic, Administrative, and Clinical Appoinments2Research Interests3Grant Support4Honors and Awards6Memberships in Professional Societies6Editorial Positions, Boards, and Peer-Review Services7Teaching9Committee, Organizational, and Volunteer Services16Consulting Positions PAGEREF _Toc405816888 \h 19Visiting Professorships, Seminars, and Extramural Invited Presentations PAGEREF _Toc405816889 \h 19Bibliography27Eric Stephen White, MDAssociate Professor of MedicineDivision of Pulmonary and Critical Care Medicine3916 TC SPC 53601500 E. Medical Center DriveAnn Arbor, MI 48109-5642(734) 647-6477(734) 936-5048 (fax)docew@umich.eduEducation and Training9/83-6/87Freeport High School, Freeport, NY8/87-5/91Tufts University, Medford, MA, B.S. Psychology7/91-5/95 State University of New York, Health Science Center at Brooklyn, Brooklyn, NY, M.D., Magna cum laude6/95-6/96Internship in Internal Medicine, University of Michigan Medical Center, Ann Arbor, MI6/96-6/98Residency in Internal Medicine, University of Michigan Medical Center, Ann Arbor, MI7/98-6/01Fellowship in Pulmonary and Critical Care Medicine, University of Michigan Medical Center, Ann Arbor, MI11/1/13“Medical Philanthropy 20/20, Vision and Practice for Funding the Future.” Advancement Resources, Ann Arbor, MI.1/30/14“Philanthropic Practices for Medical Professionals.” Advancement Resources, Ann Arbor, MI.2/24/14-2/25/14“Essential Skills for Successful Leadership.” University of Michigan Office of Faculty Development, Ann Arbor, MI.10/8/14“Development Skills for Medical Professionals.” Advancement Resources, Ann Arbor, MI.Certification and Licensure1995-Basic Life Support Provider, American Heart AssociationAdvanced Cardiac Life Support Provider, American Heart Association1997-Medical License, State of MichiganControlled Substance License, State of MichiganFederal Drug Enforcement Administration License1998-2008 American Board of Internal Medicine, Certification in Internal Medicine2001- American Board of Internal Medicine, Subspecialty Certification in Pulmonary Medicine2005-American Board of Internal Medicine, Subspecialty Certification in Critical Care MedicineAcademic, Administrative, and Clinical AppointmentsAcademic Appointments7/01-6/02Lecturer and Research Fellow, Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI7/02-6/03Lecturer, Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI7/03-8/10Assistant Professor of Medicine, Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI9/07-6/09Faculty Member, Graduate Program in Immunology, University of Michigan6/08 – present Faculty Member, Graduate Program in Cellular & Molecular Biology9/10 – 5/16 Associate Professor of Medicine, with tenure, Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI1/15 – presentFaculty Member, University of Michigan Center for Organogenesis9/16 – presentProfessor of Medicine, with tenure, Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MIAdministrative Appointments9/11 – present Medical Director, University of Michigan Sarcoidosis Clinic5/11 – 5/12Co-Chair, Planning Committee, American Thoracic Society, Respiratory Cell and Molecular Biology Assembly5/12 – 5/13 Vice Chair, American Thoracic Society Scientific Advisory Committee5/12 – 5/13Chair-Elect, Program Committee, American Thoracic Society, Respiratory Cell and Molecular Biology Assembly5/13 – 5/16 Chair, American Thoracic Society Scientific Advisory Committee5/13 – 5/14Chair, Program Committee, American Thoracic Society, Respiratory Cell and Molecular Biology Assembly11/14/14 – 11/15/14Course Director, 27th Annual Update in Pulmonary and Critical Care Medicine, University of Michigan Health Systems, Ann Arbor, MI7/1/15 – presentDirector, Translational Interstitial Lung Disease Research, Division of Pulmonary and Critical Care Medicine, University of Michigan Medical School11/13/15 – 11/14/15Course Director, 28th Annual Update in Pulmonary and Critical Care Medicine, University of Michigan Health Systems, Ann Arbor, MI1/1/16 – presentMedical Director, Ambulatory Diagnostic and Therapeutic Unit (Taubman Center and Northville Health Clinic), University of Michigan Hospitals3/1/16 – presentMedical Director, Pulmonary Ambulatory Care Unit, University of Michigan Hospitals Clinical Appointments7/99 – 4/14 Staff Physician and Consultant, Division of Pulmonary and Critical Care Medicine, Medical Service, Ann Arbor Veterans Affairs Medical Center, Ann Arbor, MI 7/99 – present Staff Physician and Consultant, Division of Pulmonary and Critical Care Medicine, University of Michigan Hospitals, Ann Arbor, MIResearch InterestsIdiopathic Pulmonary FibrosisTranslational Interstitial Lung Disease ResearchBiorepository and registry development/managementExtracellular matrixGrant SupportActiveU01 HL111016Niklasen, White (MPI)1/1/12 – 12/31/16NIH/NHLBI“Matrix and Bioreactors in Lung Regeneration”This project is part of the 6-center Lung Repair and Regeneration Consortium recently implemented by the NIH. The purpose of this project is to identify extracellular matrix proteins responsible for major epithelial, mesenchymal, and endothelial functions during lung regeneration, as well as to devise bioreactors large enough to support human lung regeneration.R01 HL123515Standiford (PI)4/1/15-3/31/19NIH/NHLBI“Novel IL-1 Family Members in Lung Innate Immunity”The purpose of this project is to investigate the role of IL-1 family members IL-36α and IL-36? in primary human BAL macrophages and in murine studies of Streptococcus pneumoniae infection.Role: Co-I T32 HL07749Standiford (PD)7/1/13-6/30/18 NIH/NHLBI “Multidisciplinary Training Program in Lung Disease”The purpose of this award is to train post-doctoral MD and/or PhD fellows in scientific approaches to Pulmonary and Critical Care Medicine ResearchRole: TrainerDrews Sarcoidosis Research Fund, Philanthropic Gift8/1/08 - presentRole: PIPulmonary and Critical Care Biorepository Research Fund11/1/15 – presentRole: PIPastNational Institutes of Health Training Grant, NHLBIT32 HL07749-07Stipend $37,680, 06/28/2000 to 06/27/2001Galen B. Toews, M.D. – Project DirectorNational Institutes of Health Training Grant, NHLBIT32 HL07749-07Stipend $40,332, 06/28/2001 to 06/27/2002Galen B. Toews, M.D. – Project DirectorNational Institutes of Health, Mentored Clinical Scientist Development Award, NHLBIK08 HL70990 $123,250 annual direct costs, 07/01/2002 to 06/30/2007Eric S. White, M.D. – Principal Investigator (9.0 calendar)American Lung Association Dalsemer Research GrantRG-036-N $35,000 annual direct costs, 07/01/2002 to 06/30/2004Eric S. White, M.D. – Principal InvestigatorYoung Investigator Fellowship Award, Pulmonary Fibrosis Foundation$25,000 annual direct costs, 07/01/2002 to 06/30/2003Eric S. White, M.D. – Principal InvestigatorT. Franklin Williams Geriatric Research Development Award, CHEST Foundation/ Association of Specialty Professors$50,000 annual direct costs, 07/01/2004 to 06/30/2006Eric S. White, M.D. – Principal InvestigatorNational Institutes of Health, Research Award, NHLBIR01 HL58897 $220,764 Annual Direct Costs, 7/1/04-6/30/08Marc Peters-Golden, M.D. – Principal InvestigatorEric S. White, M.D. – Co-Investigator (0.6 calendar)University of Michigan Pilot Grant for Translational and Clinical Research$33,000 Annual Direct Costs, 9/1/07 – 8/31/08“Pre-clinical evaluation of integrin alpha4 blockade in fibrotic lung disease”Eric S. White, M.D. – Principal Investigator (1.2 calendar)National Institutes of Health, Research Award, NHLBIR01 HL078871$250,000 Annual Direct Costs, 5/1/07-4/30/11“The Anti-protease and Vitronectin-binding Functions of PAI-1 in Lung Fibrosis”Thomas H. Sisson, M.D. – Principal InvestigatorEric S. White, M.D. – Co-Investigator (0.6 calendar)Quest for Breath Foundation, Research Award$70,000 direct costs, 6/1/06-5/31/11Eric S. White, M.D. – Principal InvestigatorCentocor Research and Development, Inc.1275148SCD2001 “A Phase 2, Multicenter, Randomized, Double-blind, Parallel Group, Placebo-controlled Study Evaluating the Safety and Efficacy of Treatment with Ustekinumab or Golimumab in Subjects with Chronic Sarcoidosis”Eric S. White, M.D. – Site Principal InvestigatorNational Institutes of Health, Research Award, NIAIDR01 AI065543$250,000 Annual Direct Costs, 5/1/07-4/30/12“PGE2 Regulation of Host Defense post BMT”Bethany B. Moore, Ph.D. – Principal InvestigatorEric S. White, M.D. – Co-Investigator (0.6 calendar)National Institutes of Health, Research Award, NHLBIR01 HL085083$250,000 Annual Direct Costs, 7/1/07-6/30/12“The Role of EIIIA Fibronectin in Pulmonary Fibrosis”Eric S. White, M.D. – Principal Investigator (6.0 calendar)National Institutes of Health, NHLBIRC2 HL101740“CTRIP: Molecular Phenotypes of Rapidly Progressive Idiopathic Pulmonary Fibrosis”$4,219,951 Annual Direct Costs, 09/30/09 – 08/31/12 (NCE 9/1/11 – 8/31/12)Martinez, White, Flaherty – Principal InvestigatorsEric S. White, M.D. – Co-Principal Investigator (1.2 calendar)U01 HL111016-CReaTv3 White, Chapman (MPI) 1/1/14–12/31/14 (NCE to 12/31/15)NIH/NHLBI“Epithelium and epithelial progenitor re-seeding of human lung scaffolds”This project is a collaborative grant between Drs. White (UM) and Chapman (UCSF) as part of the U01 Lung Repair and Regeneration Consortium. The purpose of this award is to understand mechanisms by which epithelium and epithelial progenitors adhere to extracellular matrix in human lung slices.R01 HL109118White (PI)4/1/12 – 3/31/16NIH/NHLBI“Matrix biomarkers and compartmentalization in pulmonary fibrosis”The purpose of this project is to define and validate a panel of extracellular matrix and related proteins as peripheral blood biomarkers to assist in the diagnosis and prognosis of patients with IPF.Honors and Awards1988-1991Dean's List, Tufts University1995 Alpha Omega Alpha Medical Honor Society1997, 1998, 2001Recipient, Bronze Beeper Medical Student Teaching Award, University of Michigan Medical School2002Dalsemer Award for Idiopathic Pulmonary Fibrosis Research, American Lung Association2004T. Franklin Williams Scholar Award for Geriatrics Research Development, American Geriatrics Society Foundation for Health in Aging and the Association of Subspecialty Professors20093rd Annual Carol Basbaum Award for Research Excellence, Respiratory Cell and Molecular Biology Assembly, American Thoracic Society2015Presidential Commendation for Outstanding Service, American Thoracic SocietyMembership in Professional Societies1998-American Thoracic Society1998-2003American College of Chest Physicians - Associate Member2003-American College of Chest Physicians – Fellow2007-2009University of Michigan Graduate Program in Immunology, Faculty member2008-2015American Society for Matrix Biology2008-University of Michigan Graduate Program in Cellular & Molecular Biology, Faculty member2008-World Association of Sarcoidosis and Other Granulomatous Disorders, MemberEditorial Positions, Boards, and Peer-Review ServiceEditorial Positions2011-2013Associate Editor, Journal of Pathology2013-2015Senior Editor, Journal of Pathology2013Guest Editor, Journal of Pathology Annual Review Issue “Inflammation, Wound Healing, and Fibrosis,” Jan 2013.2015-presentAssociate Editor, American Journal of Respiratory and Critical Care Medicine2016Guest Editor, Journal of Pathology Annual Review Issue “Models of Disease,” Jan 2016.Editorial Boards2008-2011Journal of Pathology2009-2011Editorial Consultant, Sarcoidosis Module, American College of Physicians “Physicians’ Information and Education Resource (PIER)”2009-presentAmerican Journal of Respiratory and Critical Care Medicine2015-presentAmerican Journal of Respiratory Cell and Molecular BiologyPeer-Review Service (ad-hoc)American Journal of Physiology – Lung Cellular and Molecular PhysiologyAmerican Journal of Respiratory Cell and Molecular BiologyAmerican Journal of Respiratory and Critical Care MedicineArthritis & RheumatismBiochimica et Biophysica ActaBloodBritish Journal of PharmacologyChestClinical Chemistry and Laboratory MedicineCurrent Medicinal Chemistry, Anti-Inflammatory and Anti-Allergy AgentsEuropean Respiratory JournalFASEB JournalHospital PhysicianInternational Journal of Radiation BiologyJournal of the American Geriatrics SocietyJournal of Biological ChemistryJournal of Clinical InvestigationJournal of the National Medical AssociationJournal of Neuro-ophthalmologyJournal of PathologyJournal of Pathology: Clinical ResearchJournal of Steroid Biochemistry and Molecular BiologyLancet Respiratory MedicineMatrix BiologyNaturePLoS OnePPAR ResearchProceedings of the American Thoracic SocietyProceedings of the National Academy of SciencesRespiratory MedicineRespiratory ResearchSaudi Medical JournalTranslational ResearchTreatments in Respiratory MedicineStudy Sections – NIH11/19/09NIAAA Special Emphasis Panel/Scientific Review Group 2010/01 ZAA1 GG (01) - Review of Alcohol Resource and Center Grant Supplement Applications6/1/10-6/2/10NHLBI Lung Injury, Repair, and Remodeling Study Section – Ad hoc member11/10/10NIAAA Special Emphasis Panel/Scientific Review Group 2011/01 ZAA1 GG (01) - Review of Alcohol Resource and Center Grant Supplement Applications1/24/12-1/25/12NHLBI Lung Cellular and Molecular Immunology Study Section 2012/05 ZRG1 CVRS-G (02) M – Member Conflicts: Lung Injury and Fibrosis3/15/12-3/16/12NHLBI Small Business Respiratory Science Study Section SEP-ZRG1 CVRS-H (11) – B7/26/12-7/27/12NHLBI Small Business Respiratory Science Study Section SEP-ZRG1 CVRS-H (11) – B2/26/13-2/27/13NHLBI Lung Cellular and Molecular Immunology Study Section 2013/05 ZRG1 CVRS-G (02) M – Member Conflicts: Lung Injury and Fibrosis7/16/13NIGMS Special Emphasis Panel Study Section 2013/10 ZGM1 CBB-0 (MI) - Macromolecular Interactions in Cells5/27/14NHLBI Special Emphasis Panel 2014/10 HLBP-I 1 – Program Project Grants11/5/14-11/6/14NHLBI Special Emphasis Panel Study Section 2015/01 ZRG1 CVRS-N (02). Member Conflicts: pulmonary fibrosis and lung injury. 3/1/16NHLBI Small Grants Program for K Awardees 2016/05 ZHL1 CSR-R (M2) 1Study Sections – United States Veterans Administration2011 – 2014Member, Panel for Pulmonary Medicine, VA Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development Services Scientific Merit Review Board.Study Sections - Foundations2005British Lung Foundation Study Section, Ad hoc member2007Pennsylvania Department of Health Final Performance Review Study Section, Ad hoc member2008Israel Science Foundation Study Section, Ad hoc member2010 – 2013 Scleroderma Foundation2010 -American Geriatrics Society Foundation for Health in Aging/Association of Subspecialty Professors T. Franklin Williams Research Scholar Award2010Medical Research Council (UK)2010 – 2016 American Thoracic Society Scientific Advisory Committee2012 – 2013Vice Chair, American Thoracic Society Scientific Advisory Committee2013 – 2016Chair, American Thoracic Society Scientific Advisory Committee2013 – 2015Member, Steering Committee, Junior Faculty Research Grant Program in IPF, InterMune, Inc.2015Wessex Medical Research (Southampton, UK)Study Sections – University of Michigan2012Biomedical Research Council Bridging Fund (July, October) – Ad hoc2015MICHR Pilot Grant Program T2 (October) – Ad hocTeachingThe University of MichiganClinical Lectures1998Division of Pulmonary and Critical Care Medicine. “Update in Bronchoscopy.”12/99Division of Pulmonary and Critical Care Medicine. “Eosinophilic Lung Disease.”10/00Division of Pulmonary and Critical Care Medicine. “Utility of 18FDG-PET in Non-Small Cell Lung Cancer.”08/01Internal Medicine House Officer Noon Conference. “Diagnosis and Management of Community-Acquired Pneumonia.”01/02Division of Pulmonary and Critical Care Medicine. “Evaluating Patients For Lung Transplantation: Can We Predict The Future?”08/02Internal Medicine House Officer Noon Conference. “Diagnosis and Management of Community-Acquired Pneumonia.”10/02Internal Medicine House Officer Noon Conference “Mechanical Ventilation in COPD.”12/02Department of Anesthesia Airway Management Course. “The Road to Disaster: Recognizing the need for airway support.”06/03Division of Pulmonary and Critical Care Medicine. “The Severe Acute Respiratory Syndrome: An overview and update.”07/03Internal Medicine House Officer Noon Conference. “Approach to the patient with Community-Acquired Pneumonia.”08/03Department of Neurosurgery Education Program. “Pulmonary issues in the neurosurgical patient.”12/03Department of Neurology Clinical Neurology Conference. “Neurosarcoidosis.”7/04Division of Pulmonary and Critical Care Medicine. “Diagnosis and management of Wegener’s granulomatosis.”9/04Internal Medicine House Officer Noon Conference. “Strategies for Mechanically Ventilating Patients with COPD.”11/04Internal Medicine House Officer Noon Conference. “Sarcoidosis.”11/04Division of Geriatric Medicine Noon Conference. “Interstitial Lung Diseases: Impact on Geriatric Populations.”7/05Internal Medicine House Officer Noon Conference. “Diagnosis and Management of Sarcoidosis.”8/05Division of Pulmonary and Critical Care Medicine. “Diagnosis and management of Wegener’s granulomatosis.”12/05Department of Ophthalmology Grand Rounds. “Manifestations and Therapy of Ocular Sarcoidosis.”3/06Department of Dermatology Resident Conference. “Diagnosis and Management of Wegener’s Granulomatosis.”6/06Department of Dermatology Resident Conference. “Manifestations and Therapy of Cutaneous Sarcoidosis.”7/07Division of Pulmonary and Critical Care Medicine. “Corticosteroids in pulmonary sarcoidosis.”11/07Department of Dermatology Resident Conference. “Manifestations and Therapy of Cutaneous Sarcoidosis.”1/08Division of Rheumatology Fellows Core Curriculum. “Sarcoidosis: An Overview.”1/08Division of Cardiology Heart Failure/Cardiac Transplantation Core Curriculum. “Cardiac Sarcoidosis.”7/08Division of Pulmonary and Critical Care Medicine Clinical Core Curriculum. “Sarcoidosis: An Overview.”2/10Internal Medicine House Officer Noon Conference. “Sarcoidosis.”7/10Division of Pulmonary and Critical Care Medicine. Case Conference Series. “Metaplastic Ossification.”1/11Division of Pulmonary and Critical Care Medicine Clinical Core Curriculum. “Sarcoidosis.”3/11Division of Otorhinolaryngology, Department of Surgery. “Surgical and Medical Management of Sarcoidosis of the Upper Respiratory Tract [SURT].”3/11Internal Medicine House Officer Noon Conference. “Sarcoidosis.”1/12Internal Medicine House Officer Noon Conference. “Sarcoidosis.”6/12Division of Rheumatology Grand Rounds. “Autoimmune diseases and ILD.”1/13Internal Medicine House Officer Noon Conference. “Sarcoidosis Basics.”3/13Medical Procedures Unit Education Hour. “Sarcoidosis.”3/13Division of Pulmonary and Critical Care Medicine Clinical Core Curriculum. “Extrapulmonary Sarcoidosis – Diagnosis and Management.”10/13Division of Pulmonary and Critical Care Medicine Fellows’ Boot Camp. “Sarcoidosis.”9/14Division of Pulmonary and Critical Care Medicine. “Sarcoidosis.”Research Lectures06/1999Division of Pulmonary and Critical Care Medicine. Research proposal: “The Role of Macrophages in Lung Cancer: Tumorigenic or Tumoricidal?”11/1999Division of Pulmonary and Critical Care Medicine. Research in Progress: “The Role of Macrophages in Non-Small Cell Lung Cancer”06/2000Division of Pulmonary and Critical Care Medicine. Research in Progress: “Macrophage Migration Inhibitory Factor in Non-Small Cell Lung Cancer”02/2001Division of Pulmonary and Critical Care Medicine. Research in Progress: “Cell-Matrix Interactions in Non-Small Cell Lung Cancer”08/2002Division of Pulmonary and Critical Care Medicine. Research in Progress: “Fibronectin Signaling in Idiopathic Pulmonary Fibrosis”10/2003Division of Pulmonary and Critical Care Medicine. Research in Progress: “Regulation of Fibroblast Migration in Fibrotic Lung Disease”11/2004Division of Pulmonary and Critical Care Medicine. Research in Progress: “A tale of two phosphatases: A PTENtial target in fibrotic lung disease?”04/2005Division of Geriatric Medicine. Basic Science Research Conference. “Pulmonary fibrosis in the aging population: relevance of fibronectin isoforms”04/2006Division of Pulmonary and Critical Care Medicine. Research in Progress: “PTEN in pulmonary fibrosis: The ongoing story”04/2007Division of Pulmonary and Critical Care Medicine. Research in Progress: “PTEN as a regulator of fibroproliferative lung disease”06/2007Division of Pulmonary and Critical Care Medicine. Research Proposal: “PTEN as a mediator of PGE2 anti-fibrotic effects” – Rommel Sagana, MD, post-doctoral fellow.07/2008Division of Pulmonary and Critical Care Medicine. Research in Progress: “Fibronectin in lung fibrosis:an obligate role for the EDA splice isoform”10/2008Division of Pulmonary and Critical Care Medicine Research Core Curriculum: “Extracellular Matrix: an introduction”8/2009Division of Pulmonary and Critical Care Medicine. Research in Progress: “The matrix in pulmonary fibrosis: what we know and what we don’t”10/2012Division of Nephrology Basic Science Group: “Role of Extracellular Matrix in Lung Fibrosis and Regeneration”2/2013Division of Pulmonary and Critical Care Medicine. Research in Progress: “Extracellular matrix biomarkers in IPF and other fibrotic disorders”2/2015Department of Internal Medicine Grand Rounds. “A Matrix-Based Approach to Understanding Interstitial Lung Disease”2/2015Bone Marrow Transplantation Research Conference. “Predicting the Future – Biomarkers in Fibrotic Lung Disease”Medical School Lectures1998-2002Respiratory physiology small group leader - medical school curriculum (ICU and bronchoscopy)1999-2002Clinical Skills Instructor, 2nd year medical students, University of Michigan Medical School2000-2002Chest physical examination, 1st year medical students, University of Michigan Medical School 2003-present Mentor, 1st year medical student ‘physician shadow’ program2003Evaluator, Clinical Curriculum Assessment, 2nd year medical students, University of Michigan Medical SchoolEvaluator, Clinical Curriculum Assessment, 4th year medical students, University of Michigan Medical SchoolGroup leader, 2nd year medical student respiratory physiology small group sessionsGroup leader, 1st year medical student respiratory physiology small group sessions2004Group leader, 2nd year medical student respiratory physiology small group sessions2005Group leader, 2nd year medical student respiratory physiology small group sessionsChest physical examination, 1st year medical students, University of Michigan Medical School2006Chest physical examination, 1st year medical students, University of Michigan Medical School2007Group leader, 2nd year medical student respiratory physiology small group sessionsPanelist for M2 elective “Spirituality: The Elephant in the Exam Room.” (Rev. Tom Burdette, organizer)2008Group leader, 2nd year medical student respiratory physiology small group sessions2010Group leader, 2nd year medical student respiratory physiology small group sessions2011Panelist for M2 elective “Spirituality: The Elephant in the Exam Room.” (Rev. Tom Burdette, organizer)2012Panelist for M2 elective “Spirituality: The Elephant in the Exam Room.” (Chaplain Ryan Swieringa, organizer)2015“Interstitial Lung Diseases.” M2 Course Lecture, Respiratory Pathophysiology Sequence, 9/11/152015Group leader, 2nd year medical student respiratory physiology small group sessions2016Science Consultant, Patient-Based Scientific Inquiry M4 Curriculum. Elizabeth Andraska, Medical Student.Program in the Biological Sciences Lectures2013“Lung ECM in Development, Homeostasis, and Disease.” In Cell and Developmental Biology 680 “Organogenesis of Complex Tissues.” 2014Panelist on “Grantsmanship.” In Pharmacology 502 “Introduction to Scientific Communication.”2015“Lung ECM in Development, Homeostasis, and Disease.” In Cell and Developmental Biology 582 “Stem Cells in Organogenesis and Regenerative Medicine.”University of Michigan Medical Center – Lectures and Clinical Service2002Internal Medicine Ambulatory Morning Report (1)Attending, Pulmonary Medicine Inpatient Service (1 month)Attending, Critical Care Medicine Service (1 month)Attending, Pulmonary Medicine Inpatient Service (1 month)Internal Medicine Resident Morning Report (3)Internal Medicine Ambulatory Morning Report (1)Internal Medicine Intern’s Report (1)Discussant, Internal Medicine Morbidity and Mortality Clinico-Pathologic Conference (1)2004Attending, Critical Care Medicine Service (1 month)Internal Medicine Ambulatory Morning Report (4)Internal Medicine Resident Morning Report (1)Internal Medicine Intern’s Report (3)2005Attending, Critical Care Medicine Service (1 month)Attending, Pulmonary Medicine Inpatient Service (1 month)Internal Medicine Intern’s Report (5)Internal Medicine Resident Morning Report (2)Internal Medicine Ambulatory Morning Report (4)Facilitator, Pulmonary Fellow Clinical Case Conference (2)2006Attending, Critical Care Medicine Service (2 weeks)Attending, Pulmonary Medicine Inpatient Service (1 month)Internal Medicine Intern’s Report (2)Internal Medicine Morbidity and Mortality Clinico-Pathologic Conference (1)Internal Medicine Resident Morning Report (4)Internal Medicine Ambulatory Morning Report (7)2007Attending, Critical Care Medicine Service (6 weeks)Attending, Pulmonary Medicine Inpatient Service (2 weeks)Internal Medicine Ambulatory Morning Report (5)Internal Medicine Resident Morning Report (1)Internal Medicine Intern’s Report (1)Internal Medicine Ambulatory Morning Report (10)Internal Medicine Resident Morning Report (1)Attending, Critical Care Medicine Service (4 weeks)Attending, Pulmonary Medicine Inpatient Service (4 weeks)Discussant, Internal Medicine Morbidity and Mortality Clinico-Pathologic Conference (1)Internal Medicine Resident Morning Report (2)Attending, Pulmonary Medicine Inpatient Service (4 weeks)Attending, Critical Care Medicine Service (4 weeks)Internal Medicine Ambulatory Morning Report (5)Internal Medicine Intern’s Report (4)Internal Medicine Ambulatory Morning Report (5)Internal Medicine Resident Morning Report (3)Internal Medicine Intern’s Report (1)Attending, Pulmonary Medicine Inpatient Service (2 weeks)Discussant, Internal Medicine Morbidity and Mortality Clinico-Pathologic Conference (1)Attending, Critical Care Medicine Service (2 weeks)Internal Medicine Ambulatory Morning Report (7)Attending, Critical Care Medicine Service (4 weeks)Internal Medicine Intern’s Report (1)Attending, Pulmonary Medicine Inpatient Service (4 weeks)Internal Medicine Resident Morning Report (2)Discussant, Internal Medicine Morbidity and Mortality Clinico-Pathologic Conference (1)2012Attending, Critical Care Medicine Service (6 weeks)Attending, Pulmonary Medicine Inpatient Service (2 weeks)Internal Medicine Ambulatory Morning Report (8)Internal Medicine Resident Morning Report (1)2013Attending, Pulmonary Medicine Inpatient Service (2 weeks)Internal Medicine Ambulatory Morning Report (4)Internal Medicine Resident Morning Report (2)Attending, Critical Care Medicine Service (4 weeks)2014Attending, Critical Care Medicine Service (4 weeks)Internal Medicine Ambulatory Morning Report (6)2015Internal Medicine Ambulatory Morning Report (6)Department of Internal Medicine Grand Rounds. “A Matrix-Based Approach to Understanding Interstitial Lung Disease” (2/13/15)Attending, Critical Care Medicine Service (6 weeks)Internal Medicine Resident Morning Report (4)2016Internal Medicine Ambulatory Morning Report (3)Attending, Critical Care Medicine Service (8 weeks)Supervisory activities (current and former trainees):Jessica Tsui, MD, supervised as Medical Student and Internal Medicine Resident (Clinical and Laboratory)Marc R. McClelland, MD, supervised as Pulmonary Fellow (Clinical and Laboratory)Steven K. Huang, MD, supervised as Pulmonary Fellow (Clinical and Laboratory)Shail Mehta, MD, supervised as Internal Medicine Resident (Laboratory)David Stephenson, MD, supervised as Internal Medicine Resident (Laboratory)Rommel Sagana, MD, supervised as Pulmonary Fellow (Clinical and Laboratory)Anthony Courey, MD, supervised as Pulmonary Fellow (Clinical and Laboratory)Benjamin Murdock, supervised as PhD Candidate (Laboratory)Adam Booth, supervised as PhD Candidate and Post-Doctoral Fellow (Laboratory) – Awarded Parker B. Francis Fellowship (declined)Leah Hubbard, supervised as PhD Candidate (Laboratory)Ryan Hadley, MD, supervised as Pulmonary Fellow (Clinical and Laboratory)Stephanie Matthes, PhD, supervised as Post-Doctoral Fellow (Laboratory)Emily Speelmon, MD, PhD, supervised as Pulmonary Fellow (Clinical and Laboratory)Committee, Organizational, and Volunteer ServiceUniversity of Michigan Medical School6/95 – 6/96House Officer Education Committee, University of Michigan Hospitals10/04 – 12/04Chair, University of Michigan Pulmonary Fellowship Program ‘Quality of Life and Recruitment Committee’10/04 – 12/04Member, University of Michigan Pulmonary Fellowship Program ‘Conference Committee’12/04 – presentAd hoc Internal Medicine Residency Applicant Reviewer, University of Michigan Health System10/05 – presentAd hoc member, Medical School Admissions Committee, University of Michigan Medical School7/1/05 – 6/30/07Member, Thesis Advisory Committee, Steven K. Huang, MD7/1/07 – 6/30/09Chair, Thesis Advisory Committee, Rommel Sagana, MD1/10/08 – 6/30/09Member, Thesis Advisory Committee, Anthony J. Courey, MD11/1/09 – 10/31/12Chair, Thesis Advisory Committee, Adam J. Booth, Ph.D.7/1/11 – 6/30/13Chair, Thesis Advisory Committee, Ryan Hadley, MD11/1/11 – 10/31/15Chair, Thesis Advisory Committee, Stephanie A. Matthes, PhD7/1/12 – 6/30/14Chair, Thesis Advisory Committee, Emily Speelmon, MD, PhD1/15/12 – 1/14/14Internal Subject Matter Expert (Extracellular matrix biology), Laure Rittié, PhD (Department of Dermatology, University of Michigan)9/13 – presentMember, Division of Pulmonary and Critical Care Medicine Mentoring Committee10/14 – presentMember, Division of Pulmonary and Critical Care Medicine Clinical Competency Committee1/16 – presentMember, Medical School Central Biorepository Governance CommitteeUniversity of Michigan Hospitals and Health Center11/14 – presentMember, Ambulatory Infusion Advisory CommitteeUniversity of Michigan Graduate Program in the Biological Sciences7/1/07 – 9/30/10Co-Chair (with Gary Huffnagle, PhD), Thesis Advisory Committee, Benjamin J. Murdock, Graduate Program in Immunology7/1/07 – 10/31/09Member, Thesis Advisory Committee, Adam J. Booth, Graduate Program in Immunology7/1/08 – 3/31/11Member, Thesis Advisory Committee, Leah L. N. Hubbard, Graduate Program in Immunology9/5/08Poster Judge, Cellular and Molecular Biology Graduate Student Poster Symposium4/14/09Member, Preliminary Exam Committee, Jeffrey D. Calhoun, Graduate Program in Cellular & Molecular Biology5/27/09Co-Chair, Cellular & Molecular Biology Graduate Student Research Forum9/09/09Poster Judge, Cellular and Molecular Biology Graduate Student Poster Symposium2009-2013Member, Thesis Advisory Committee, Jeffrey D. Calhoun, Graduate Program in Cellular & Molecular Biology2009 – 2010CMB 850 (Student Seminar) Faculty Evaluator2010 – 2011CMB 850 (Student Seminar) Faculty Evaluator2012 – 2015Member, Thesis Advisory Committee, Gabriel Martinez-Santibanez, Graduate Program in Cellular & Molecular Biology2012 – 2015Member, Thesis Advisory Committee, Jose Nieves-Rodriguez, Graduate Program in Cellular & Molecular Biology2013 – 2016Member, Thesis Advisory Committee, Briana (Rockich) Dye, Graduate Program in Cell & Developmental BiologyNational5/06 – 5/09Member, International Conference Programming Committee, American Thoracic Society, Respiratory Cell and Molecular Biology Assembly5/06 – 5/09Head, Section on Fibroblast Biology and Pulmonary Fibrosis, International Conference Programming Committee, American Thoracic Society, Respiratory Cell and Molecular Biology Assembly9/07 – 5/15Member, T. Franklin Williams Scholars Annual Meeting Planning Committee, Association of Subspecialty Professors10/08 – 10/12Member, Interstitial and Diffuse Lung Disease NetWork Steering Committee, American College of Chest Physicians5/10 – 5/16Member, Scientific Advisory Committee, American Thoracic Society5/10 – 5/11Member, Nominating Committee, American Thoracic Society, Respiratory Cell and Molecular Biology Assembly5/11 – 5/12Co-Chair, Planning Committee, American Thoracic Society, Respiratory Cell and Molecular Biology Assembly5/12 – presentMember, Planning Committee, American Thoracic Society, Respiratory Cell and Molecular Biology Assembly5/12 – 5/13Chair-Elect, Program Committee, American Thoracic Society, Respiratory Cell and Molecular Biology Assembly5/12 – 5/13Vice Chair, Scientific Advisory Committee, American Thoracic Society5/13 – 5/16Chair, Scientific Advisory Committee, American Thoracic Society5/13 – 5/14Chair, Program Committee, American Thoracic Society, Respiratory Cell and Molecular Biology Assembly5/13 – 4/15Member, Steering Committee, Junior Faculty Research Grant Program in IPF, InterMune, Inc.5/19/13Chair, ATS RCMB Working Group on Lung Fibrosis Biologic Sample Planning Meeting11/6/14 – present Member, The Liver Forum, Forum for Collaborative HIV Research12/1/14 – presentMember, Medical Advisory Board, Pulmonary Fibrosis FoundationInternational7/11External Evaluator, Doctoral Thesis of Jill Ann Marie Fielhaber (“Regulation of signal transducer and activator of transcription-1 and cell death by mammalian target of rapamycin”), PhD Candidate, McGill University. Mentor: Arnold Kristof, BSc, MDCM.1/12External Evaluator, Master’s Thesis of Grace Chau (“ED-A fibronectin: a specific storage site for latent TGF?-1 in the myofibroblast matrix?”), MSc Candidate, University of Toronto. Mentor: Boris Hinz, PhD. Consulting Positions2009 – 2010 Advisory Board, ?lan Pharmaceuticals (Idiopathic Pulmonary Fibrosis2010 – 2011 Advisory Board, Oncothyreon Pharmaceuticals (Idiopathic Pulmonary Fibrosis)2013 – present Consultant and Advisory Board, Boehringer-Ingelheim Pharmaceuticals, Inc. (Idiopathic Pulmonary Fibrosis)2013 – 2014 Consultant, EMD Serono (Scleroderma-associated interstitial lung disease)2015 – 2016Kadmon Corporation (Idiopathic Pulmonary Fibrosis) Visiting Professorships, Seminars, and Extramural Invited PresentationsInternational1/16/07“The role of the EDA splice isoform of fibronectin in pulmonary fibrosis.” EMBO Conference Series/ EURASNET WP12 Interdisciplinary Focus meeting on pre-mRNA splicing and disease. Cortina d’Ampezzo, Italy.5/18/08“Therapeutic options in sarcoidosis management.” Meet-the-Professor Seminar. American Thoracic Society International Conference, Toronto, Ontario, Canada.5/20/08“Clinical management dilemmas in sarcoidosis.” Clinical Workshop Co-chair. American Thoracic Society International Conference, Toronto, Ontario, Canada.5/21/08“Novel insights into the pathogenesis of pulmonary fibrosis: Lessons from animals and man.” Symposium Co-chair. American Thoracic Society International Conference, Toronto, Ontario, Canada.11/2/10“Case Reports: Drug-Induced Interstitial Lung Disease.” Symposium Moderator. American College of Chest Physicians Annual Conference. Vancouver, British Columbia, Canada.11/3/10“Utility and Scope of Biomarkers in Interstitial Lung Disease.” Symposium Chair, Session on Biomarkers in Interstitial Lung Disease. American College of Chest Physicians Annual Conference. Vancouver, British Columbia, Canada.1/11/12“Extracellular Matrix in Lung Fibrosis and Regeneration” Visiting Professor, University of Toronto Extracellular Matrix Dynamics Program, Dr. Boris Hinz, host. Toronto, Ontario, Canada.6/27/13“The Extracellular Matrix in Pulmonary Fibrosis: More Than Just an Endpoint.” Invited Speaker, International Graduate Program - Molecular Biology and Medicine of the Lung Annual Retreat. Giessen, Germany10/4/13“Standardization of animal models of IPF across centers – scientific necessity or ethical mandate?” Invited Speaker, ERS Research Seminar - Optimising models for human lung diseases and drug development. Paris, France.9/4/14“Fibronectin isoforms in lung fibrosis.” Invited Speaker, Munich International Autumn School. Munich, Germany.9/6/14“Pulmonary fibrosis: receptors, signalling pathways and mesenchymal cells.” Poster Discussion Chair. European Respiratory Society International Congress. Munich, Germany.9/24/14“The Future of IPF Basic Science Research.” International Colloquium on Lung and Airway Fibrosis. Mont Tremblant, Canada.12/3/14“The next dimension: 3D in vitro modeling of fibrotic lung disease.” British Thoracic Society Winter Meeting, London, United Kingdom.6/3/16“Extracellular matrix in the diagnosis and management of lung fibrosis.” Canadian Connective Tissue Society Conference, Toronto, Canada.6/11/16“Diagnosis and Management of Idiopathic Pulmonary Fibrosis.” National Annual Update in Pulmonary and Critical Care Medicine Conference. Sichuan Academy of Medical Science, Sichuan Provincial People’s Hospital, University Hospital of Electronic Science & Technology of China, Chengdu, China.National1/18/02“Idiopathic Pulmonary Fibrosis: Lessons Learned From Cancer?” Visiting Lecturer. Case Western Reserve University Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine Grand Rounds. Cleveland, OH.4/30/02“Idiopathic Pulmonary Fibrosis and Non-Small Cell Lung Cancer: Diseases Linked By Fibronectin.” Visiting Lecturer. Emory University School of Medicine, Department of Internal Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine Grand Rounds. Atlanta, GA.5/19/03“Session WS3: Master Clinicians: Pulmonary Fibrosis.” Chairperson/Discussant. American Thoracic Society International Conference. Seattle, WA.5/21/03“Session D104: Rare Diffuse Lung Diseases.” Thematic Poster Session Facilitator. American Thoracic Society International Conference. Seattle, WA.5/25/04“Pathogenetic Mechanisms of Idiopathic Pulmonary Fibrosis.” Sunrise Seminar Speaker. American Thoracic Society International Conference. Orlando, FL.1/31/05“The Role of PTEN in Pulmonary Fibrosis.” Visiting Lecturer. Indiana University Medical Center, Department of Internal Medicine, Division of Pulmonary, Allergy, Critical Care, and Occupational Medicine Grand Rounds. Indianapolis, IN. 5/24/05“Management of Wegener’s Granulomatosis.” Sunrise Seminar Speaker. American Thoracic Society International Conference. San Diego, CA.5/25/05“More Than Just Glue: Matrix Regulation of Lung Biology.” Session Co-chair. American Thoracic Society International Conference. San Diego, CA.6/9/05“The effect of PTEN in modulating fibroblast behavior in pulmonary fibrosis.” Visiting Professor. Mount Sinai School of Medicine, Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine Grand Rounds. New York, NY.5/21/06“Session A135: Growth Factors, Cell Matrix Interactions And Basic Mechanisms Of Tissue Fibrosis And Remodeling.” Poster Session Facilitator. American Thoracic Society International Conference, San Diego, CA.5/22/06“Management of Wegener’s Granulomatosis.” Sunrise Seminar Speaker. American Thoracic Society International Conference. San Diego, CA.8/8/06“Cellular fibronectin as a regulator of fibroproliferative lung disease.” Visiting Professor. Emory University School of Medicine, Department of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine Grand Rounds. Atlanta, GA.4/24/07“PTEN as a regulator of fibroproliferative lung disease.” Visiting Professor. Cleveland Clinic Department of Pathobiology Seminar. Cleveland, OH.4/25/07“Fibronectin Contributions to Fibrosis in IPF: A Potential Target for Therapy?” Visiting Professor. Cleveland Clinic Department of Pulmonary, Allergy, and Critical Care Medicine Grand Rounds. Cleveland, OH.10/29/08“Cytokines and Cellular Interactions.” Poster Session Moderator. American College of Chest Physicians/CHEST Annual Assembly, Philadelphia, PA.10/29/08“Wild Interstitial Lung Diseases.” Expert Panelist. American College of Chest Physicians/CHEST Annual Assembly, Philadelphia, PA.1/10/09“EDA fibronectin as a contributor to organ fibrosis.” Visiting Professor. University of Southern California Division of Pulmonary and Critical Care Medicine Research Grand Rounds. Los Angeles, CA.5/18/09“Translational Investigation into Mechanisms of Lung Fibrosis.” Poster Discussion Chair. American Thoracic Society International Conference. San Diego, CA.5/18/09“Pulmonary Fibrosis: The Fibroblast.” Thematic Poster Session Lead Facilitator. American Thoracic Society International Conference. San Diego, CA.5/19/09“Interstitial Lung Disease and Connective Tissue Diseases II.” Thematic Poster Session Facilitator. American Thoracic Society International Conference. San Diego, CA.7/17/09“The role of EDA Fibronectin in Pulmonary Fibrosis.” Visiting Professor. University of Utah Division of Pulmonary, Critical Care, and Occupational Medicine. Salt Lake City, UT.4/9/10“PTEN and the fibroblast in Pulmonary Fibrosis: a Rationale for Studies in LAM.” The LAM Foundation 2010 International Research Conference, Cincinnati, OH.4/23/10“The Extracellular Matrix in IPF: What we know and what we don’t.” Visiting Professor. University of Louisville Division of Pulmonary, Critical Care, and Sleep Medicine. Louisville, KY.5/15/10“Grant Fundamentals.” Post-Graduate Course PG25 Co-Chair, American Thoracic Society International Conference, New Orleans, LA.5/16/10“Animal Models of Pulmonary Fibrosis.” Thematic Poster Session Facilitator. American Thoracic Society International Conference, New Orleans, LA.5/17/10“Using Patient Samples to Understand Pulmonary Fibrosis.” Thematic Poster Session Lead Facilitator. American Thoracic Society International Conference, New Orleans, LA.5/17/10“Early Detection Of Lung Tissue Remodeling: Novel Biomarkers Of Postnatal Lung Disease Progression.” Vascular Matrix Interactions in Lung Development and Disease Mini-Symposium. American Thoracic Society International Conference, New Orleans, LA.5/18/10“Pathobiology of Idiopathic Pulmonary Fibrosis.” Meet the Professor Session. American Thoracic Society International Conference, New Orleans, LA.5/19/10“Fibronectin Regulation of Pulmonary Fibrosis.” Breaking it Down: Matrikines and Lung Disease in 2010 Mini-Symposium. American Thoracic Society International Conference, New Orleans, LA.10/5/10“The Extracellular Matrix in IPF: What we know and what we need to learn.” Visiting Professor. University of Cincinnati Children’s Hospital Medical Center and Division of Pulmonary, Critical Care, and Sleep Medicine. Cincinnati, OH.10/13/10“Therapy for Interstitial Lung Disease: What we think we know.” Visiting Professor. Wayne State University Division of Pulmonary, Critical Care, and Sleep Medicine Pulmonary Grand Rounds. Detroit, MI.1/4/11“The extracellular matrix and lung regeneration: Building the perfect beast.” Visiting Professor. Medical University of South Carolina, Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine. Charleston, SC.5/15/11“High-Throughput Plasma Biomarker Analysis in IPF Reveals An Extracellular Matrix Remodeling Signature.” Cutting Edge Insights to the Pathobiology of COPD and Interstitial Lung Disease Mini-Symposium. American Thoracic Society International Conference, Denver, CO.5/17/11“Hypersensitivity Pneumonitis, Sarcoid, and Granuloma Models.” Thematic Poster session Lead Facilitator. American Thoracic Society International Conference, Denver, CO.5/18/11“Sarcoid: Advances in Diagnosis, Staging, and Treatment.” Chair, Poster Discussion Session. American Thoracic Society International Conference, Denver, CO.10/13/11“Lung regeneration: the extracellular matrix takes center stage.” Visiting Professor. Tulane University, Division of Pulmonary Diseases, Critical Care, and Environmental Medicine, New Orleans, LA.10/27/11“Interstitial Lung Disease Cases II: 2011” Expert Panelist. American College of Chest Physicians/CHEST Annual Assembly, Honolulu, HI.10/27/11“ILD Posters: 2011” Poster Session Moderator. American College of Chest Physicians/CHEST Annual Assembly, Honolulu, HI.10/27/11“Hypersensitivity Pneumonitis: Variations in Diagnosis and Management: 2011” Symposium Chair. American College of Chest Physicians/CHEST Annual Assembly, Honolulu, HI.10/27/11“Interstitial Lung Disease: 2011” Scientific Symposium co-Chair. American College of Chest Physicians/CHEST Annual Assembly, Honolulu, HI.12/1/11“Lung Regeneration: The Extracellular Matrix Takes Center Stage” Visiting Speaker, Northwestern University Division of Rheumatology, Dr. John Varga, host. Chicago, IL.12/2/11“Fibroblasts and Extracellular Matrix: Too Much of a Good Thing?” Faculty Presenter, Inaugural IPF Summit 2011: From Bench to Bedside, The Pulmonary Fibrosis Foundation, Chicago, IL.2/2/12“Lessons Learned from Other Disciplines: Laboratory Insights into Pulmonary Fibrosis” Session #1, Pediatric AM Concurrent: Sclerotic and Fibrotic Manifestations of Chronic GVHD. American Society for Bone Marrow Transplantation/Center for International Blood & Marrow Transplant Research Tandem Meetings, San Diego, CA.2/5/12“Tissue Fibrosis: Too Much of a Good Thing?” Scientific Plenary Session #5, Understanding Chronic GVHD from Different Angles. American Society for Bone Marrow Transplantation/Center for International Blood & Marrow Transplant Research Tandem Meetings, San Diego, CA.3/10/12“Assessing the Extracellular Matrix in Lung Injury, Fibrosis, and Regeneration” American Thoracic Society ‘Fibrosis Across Organ Systems’ Symposium. Denver, CO.7/19/12“Acellular Human Lung to Examine the Role ofExtracellular Matrix in Lung Fibrosis.” Gilead Sciences Visiting Professor. Foster City, CA.3/20/13“Human Lung Extracellular Matrix: Defining the Substrate.” 17th Annual Hilton Head Workshop on Regenerative Medicine Short Course 2013. Hilton Head, SC.5/17/13“Modeling Human Lung Disease: A Toolbox for Meaningful Measurements.” Chair, Post-Graduate course. American Thoracic Society International Conference, Philadelphia, PA. 5/20/13“Proteomic analysis of the lung ECM: applications to help understand disease.” Scientific Symposium “Exciting Technological Advances for Understanding the Extracellular Matrix.” American Thoracic Society International Conference, Philadelphia, PA.5/20/13“Understanding The Role of The ECM In Lung Regeneration And Repair.” Scientific Symposium “Exciting Technological Advances for Understanding the Extracellular Matrix.” American Thoracic Society International Conference, Philadelphia, PA.5/21/13“The NIH Lung Repair and Regeneration Consortium (LRRC): An Update.” Chair, Scientific Symposium. American Thoracic Society International Conference, Philadelphia, PA.5/21/13“The Role Of Lung ECM In Driving Cellular Phenotype During Lung Repair and Regeneration.” Scientific Symposium “The NIH Lung Repair and Regeneration Consortium (LRRC): An Update.” American Thoracic Society International Conference, Philadelphia, PA.6/4/13“Extracellular Matrix in Interstitial Lung Disease: Pathogenic and prognostic?” Visiting Professor, University of Pittsburgh Division of Pulmonary, Allergy, and Critical Care Medicine, Pittsburgh, PA.8/19/13“Idiopathic Pulmonary Fibrosis: Where are we going?” Boehringer-Ingelheim Academic Grand Rounds Visiting Professor. Danbury, CT. 9/24/13“The Scientific Process as it Relates to Human Lung Disease Research.” NIH 2nd Annual Lung Repair and Regeneration Consortium Speaker. Philadelphia, PA.10/22/13"Fibrosis – Therapeutic Target or Inevitable Outcome?" Invited Speaker, Session: "Extracellular Matrix and related molecules as biomarkers for patients with idiopathic pulmonary fibrosis." New York Academy of Sciences, New York, NY.3/20/14“Extracellular Matrix in Pulmonary Fibrosis: Not just an Endpoint.” Louisiana State University Health Science Center Department of Physiology Visiting Professor. New Orleans, LA.4/17/14“Registries, Biorepositories, and Biomarkers: The Future of Interstitial Lung Disease Research.” Boehringer-Ingelheim Academic Grand Rounds Visiting Professor. Danbury, CT.4/27/14 – 4/29/14“Anatomy and cellular differences – reagents and models needed.” Workgroup Chair, Fibrosis Across Species Conference. Louisville, KY.5/17/14“The Aging Lung Matrix.” In Postgraduate Course 20: “HOW TO STUDY THE AGING LUNG.” American Thoracic Society International Conference, San Diego, CA.5/18/14“ATS Program of Research.” In “Nursing Research Funding Opportunities.” American Thoracic Society International Conference, San Diego, CA.5/20/14“Fibroblasts and the Abnormal Matrix as the Central Player in IPF Pathogenesis.” In Scientific Symposium “ATS MYTHBUSTERS: REPETITIVE MICRO-INJURIES DRIVE IPF PROGRESSION.” American Thoracic Society International Conference, San Diego, CA.6/5/14“Extracellular Matrix Stiffness and Fibroblast Function.” The Roger S. Mitchell Lecture, Thomas L. Petty 57th Annual Aspen Lung Conference, Aspen, CO.7/24/14“Extracellular Matrix – Pathogenic and Prognostic in IPF.” Visiting Professor, National Jewish Health, Denver, CO.8/28/14“The Extracellular Matrix in Pulmonary Fibrosis: More Than Just an Endpoint.” Visiting Professor, Weill Cornell Medical College, New York, NY.2/26/15“Understanding human lung fibrosis: Harnessing the power of the patient.” Invited Seminar Speaker, Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.3/19/15“Towards human lung regeneration: progress and challenges.” Visiting Professor, Research and Innovation Conference, University of Colorado – Denver School of Medicine, Denver, CO.5/18/15“ATS Program of Research.” American Thoracic Society International Conference, Denver, CO.5/19/15“Matrix Mania: The Complex Webs We Weave?” Poster Discussion Chair, American Thoracic Society International Conference, Denver, CO.5/20/15“How and Why We Should Share Biologic Samples Despite the Many Challenges.” In Scientific Symposium “Advancing the Foundation for Global IPF Clinical Research: Registries, Biorepositories, and Collaborative Science.” American Thoracic Society International Conference, Denver, CO.NIH9/15/11, 9/16/11“The Role of Extracellular Matrix in Lung Fibrosis.” Insights into the Pulmonary Fibrosis of Hermansky-Pudlak Syndrome Workshop, NHGRI/NHLBI. Rockville, MD.11/27/12, 11/28/12“Modeling the ECM in IPF.” Idiopathic Pulmonary Fibrosis Strategic Planning Workshop, NHLBI. Rockville, MD.9/17/14, 9/18/14“Models of ECM in Lung Research.” Extracellular Matrix in Lung Disease Workshop, NHLBI. Bethesda, MD.Regional2/19/01, 2/20/01“Pressure Controlled Ventilation,” Ann Arbor Veterans Affairs Hospital, Department of Respiratory Therapy. Ann Arbor, MI.5/13/04“Diagnosis and Management of Idiopathic Pulmonary Fibrosis.” Hurley Medical Center Internal Medicine Grand Rounds. Flint, MI.11/3/04“Diagnosis and Management of Sarcoidosis.” Oakwood Hospital Medical Residency Lecture Series. Dearborn, MI.12/8/04“Diagnosis and Management of Idiopathic Interstitial Pneumonias.” Oakwood Hospital Medical Residency Lecture Series. Dearborn, MI. 10/25/06“Sarcoidosis: The Basics.” Oakwood Hospital Medical Residency Lecture Series. Dearborn, MI.12/8/07“Idiopathic Pulmonary Fibrosis.” Belleville High School Lung Health Awareness Seminar, Belleville, MI.6/10/09“Interstitial Lung Diseases: A case-based approach.” Oakwood Hospital Medical Residency Lecture Series. Dearborn, MI.9/16/09“Sarcoidosis: an update.” William H. Beaumont Hospital, XII Annual Chest Conference. Royal Oak, MI9/30/10“Update on Pulmonary Sarcoidosis Management.” University of Michigan 23rd Annual Update in Pulmonary and Critical Care Medicine Symposium. Ann Arbor, MI9/13/12“Acellular Human Lung to Examine the Role ofExtracellular Matrix in Lung Fibrosis.” Gift of Life Michigan Lunch and Learn Series. Ann Arbor, MI.9/27/12“Immunosuppressive Management of Sarcoidosis and other ILDs.” University of Michigan 25th Annual Update in Pulmonary and Critical Care Medicine Symposium. Ann Arbor, MI.5/9/14“Can’t Sarcoidosis Look like ANYTHING?” University of Michigan Department of Medicine 2nd Annual Update in Internal Medicine. Ann Arbor, MI.4/13/15“Sarcoidosis.” Internal Medicine Grand Rounds, MidMichigan Medical Center, Midland, MI.11/20/15“Therapeutic options in IPF.” Pulmonary Fibrosis Identification: Lessons for Optimizing Treatment (PILOT). France Foundation and the Pulmonary Fibrosis Foundation, Lansing, MI.12/1/15“Idiopathic Pulmonary Fibrosis Research.” IPF Patient Support Group Meeting, Ann Arbor, MI.3/24/16“Diagnosis and Management of Sarcoidosis.” St. John Providence Hospital Grand Rounds, Southfield, MI.BibliographyPublications: Peer-ReviewedRB Kanarek, ES White, MT Biegen, and R. Marks-Kaufman. Dietary influences on morphine-induced analgesia in rats. 1991. Pharm Biochem Behav. 38(3): 681-4. ES White and JP Lynch III. Sarcoidosis involving multiple systems: diagnostic and therapeutic challenges. 2001. Chest 119:1593-1597. ES White, SRB Strom, NL Wys, and DA Arenberg. Non-small cell lung cancer cells induce monocytes to increase expression of angiogenic activity. 2001. J Immunol 166(12): 7549-7555.ES White, DL Livant, S Markwart, and DA Arenberg. Monocyte-fibronectin interactions, via 51 integrin, induce expression of CXC chemokine-dependent angiogenic activity. 2001. J Immunol 167(9): 5362-5366.DA Arenberg, ES White, MD Burdick, SRB Strom, and RM Strieter. Improved survival in tumor bearing SCID mice treated with interferon--inducible protein 10 (IP-10/CXCL10). 2001. Cancer Immunol Immuno 50(10): 533-538.JP Lynch III, ES White, and KR Flaherty. Corticosteroids in idiopathic pulmonary fibrosis (IPF). 2001. Curr Opin Pulm Med 7: 298-308.JP Lynch III, M Wurfel, KR Flaherty, ES White, FJ Martinez, WD Travis, and G Raghu. Usual interstitial pneumonia. 2001. Sem Resp Crit Care Med 22(4): 357-385. KR Flaherty, ES White, SE Gay, FJ Martinez, and JP Lynch III. Timing of lung transplantation for patients with fibrotic lung diseases. 2002. Sem Resp Crit Care Med 22(5): 517-531. ES White, RM Strieter, and DA Arenberg. Chemokines as therapeutic targets in non-small cell lung cancer. 2002. Current Med Chem. 2(3): 403-417. ES White, MH Lazar, and VJ Thannickal. Pathogenetic Mechanisms in Usual Interstitial Pneumonia/Idiopathic Pulmonary Fibrosis. 2003. J Pathol. 201:343-354.ES White, HD Tazelaar, and JP Lynch III. Bronchiolar Complications of Connective Tissue Diseases. 2003. Sem Resp Crit Care Med. 24(5): 543-566. ES White, KR Flaherty, SL Carskadon, A Brant, MD Iannetoni, J Yee, MB Orringer, and DA Arenberg. Macrophage migration inhibitory factor (MIF) and CXC chemokine expression in non-small cell lung cancer (NSCLC): Role in angiogenesis and prognosis. 2003. Clin Cancer Res. 9: 853-860.VJ Thannickal, DY Lee, ES White, Z Cui, JM Larios, R Chacon, JC Horowitz, RM Day, and PE Thomas. Myofibroblast differentiation by TGF-1 is dependent on cell adhesion and integrin signaling via focal adhesion kinase. 2003. J Biol Chem. 278(14): 12384-12389.SI Moore, GB Huffnagle, GH Chen, ES White, and P Mancuso. Leptin modulates neutrophil phagocytosis of K. pneumoniae. 2003. Infect Immun. 71: 4182-4185. PMCID: PMC161963ES White, VJ Thannickal, SL Carskadon, EG Dickie, DL Livant, S Markwart, GB Toews, and DA Arenberg. Integrin 41 regulates migration across basement membranes by lung fibroblasts: A role for phosphatase and tensin homologue deleted on chromosome ten. 2003. Am J Resp Crit Care Med. 168: 436-442. PMCID: PMC1997294JM Beck, AM Preston, SE Wilcoxen, SB Morris, ES White, and R Paine. Pneumocystis carinii pneumonia increases the susceptibility of mice to sublethal hyperoxia. 2003. Infect Immun. 71(10): 5970-5978. PMCID: PMC201097MH Lazar, PJ Christensen, M Du, B Yu, NM Subbotina, KE Hanson, JM Hansen, ES White, RH Simon, and TH Sisson. Plasminogen Activator Inhibitor-1 impairs alveolar epithelial repair by binding to vitronectin. 2004. Am J Resp Cell Mol Biol. 31:672-678. JP Lynch III, ES White, HD Tazelaar, and CA Langford. Wegener’s Granulomatosis: Evolving Concepts in Treatment. 2004. Sem Resp Crit Care Med. 26(5): 491-522. VJ Thannickal, GB Toews, ES White, JP Lynch III, and FJ Martinez. Mechanisms of Pulmonary Fibrosis. 2004. Ann Rev Med. 55:395-417. ES White, RG Atrasz, EG Dickie, DM Aronoff, V Stambolic, TW Mak, BB Moore, and M Peters-Golden. Prostaglandin E2 inhibits fibroblast migration by EP2 receptor-mediated increase in PTEN activity. 2005. Am J Resp Cell Mol Biol. 32:135-141. PMCID: PMC1965457BB Moore, MN Ballinger, ES White, ME Green, AB Herrygers, CA Wilke, GB Toews, and M Peters-Golden. Bleomycin-induced E prostanoid receptor changes alter fibroblast responses to prostaglandin E2. 2005. J Immunol. 174:5644-5649.ES White, CA Langford, HD Tazelaar, and JP Lynch III. Management of Wegener Granulomatosis. 2005. Clin Pulm Med. 12(4): 220-231. ES White, RG Atrasz, B Hu, SH Phan, V Stambolic, TW Mak, CM Hogaboam, KR Flaherty, FJ Martinez, CD Kontos, and GB Toews. Negative regulation of myofibroblast differentiation by PTEN. 2006. Am J Resp Crit Care Med. 173: 112-121. PMCID: PMC1434700RS Nho, H Xia, D Diebold, J Kahm, J Kleidon, ES White, and CA Henke. PTEN regulates fibroblast elimination during collagen matrix contraction. 2006. J Biol Chem. 281: 33291-33301. ES White and JP Lynch III. Pharmacological Therapy for Wegener’s Granulomatosis. 2006. Drugs. 66(9):1209-1228. JP Lynch III, R Saggar, SS Weigt, DA Zisman, and ES White. Usual Interstitial Pneumonia. 2006. Sem Resp Crit Care Med. 27(6): 634-651. MR McClelland, S Carskadon, L Zhao, ES White, DG Beer, MB Orringer, A Pickens, AC Chang, and DA Arenberg. Diversity of the angiogenic phenotype in non-small cell lung cancer. 2007. Am J Resp Cell Mol Biol. 36: 343-350. PMCID: PMC1899317JC Horowitz, V Sharma, R Vittal, ES White, Z Cui, and VJ Thannickal. Combinatorial activation of FAK and Akt by transforming growth factor-1 confers an anoikis-resistant phenotype to myofibroblasts. 2007. Cell Signal. 19(4): 761-71. PMCID: PMC1820832PE Thomas, M Peters-Golden, ES White, VJ Thannickal, and BB Moore. PGE2 inhibition of TGF-β1 induced fibroblast to myofibroblast differentiation is SMAD-independent, but involves cell shape and adhesion-dependent signaling. 2007. Am J Physiol – Lung. 293(2): L417-428. PMCID: PMC2846428C Canetti, CH Serezani, RG Atrasz, ES White, DM Aronoff, and M Peters-Golden. Activation of phosphatase and tensin homologue on chromosome ten (PTEN) mediates the inhibition of Fcγ receptor phagocytosis by prostaglandin E2 in alveolar macrophages. 2007. J Immunol. 179: 8350-8356.JP Lynch III, YL Ma, MN Koss, and ES White. Pulmonary Sarcoidosis. 2007. Sem Resp Crit Care Med. 28(1): 53-74. ES White and JP Lynch III. Current and Emerging Strategies for the Management of Sarcoidosis. 2007. Expert Opin Pharmacother. 8(9): 1293-1311.AF Muro, FA Moretti, BB Moore, M Yan, RG Atrasz, CA Wilke, KR Flaherty, FJ Martinez, JL Tsui, C Marcinkiewicz, D Sheppard, FE Baralle, GB Toews, and ES White. An essential role for fibronectin extra type III domain A in lung fibrosis. 2008. Am J Resp Crit Care Med. 177(6):638-645. PMCID: PMC2267338GA Yanik, V Ho, J Levine, ES White, T Braun, J Antin, J Whitfield, J Custer, D Jones, JLM Ferrara, and KR Cooke. The impact of soluble tumor necrosis factor receptor: etanercept (Enbrel?) on the treatment of idiopathic pneumonia syndrome following allogeneic hematopoietic stem cell transplantation. 2008. Blood. Oct 15;112(8):3073-81. PMCID: PMC3045267ES White, FE Baralle, and AF Muro. New insights into form and function of fibronectin splice variants. 2008. J Pathol. 216(1):1-14.M Sodhi, K Pearson, ES White, and DA Culver. Infliximab therapy rescues cyclophosphamide failure in severe central nervous system sarcoidosis. 2009. Respir Med. Feb;103(2):268-73.M Takeshima, CJ Parsons, K Ikejima, S Watanabe, ES White, RA Rippe. The tumor suppressor protein PTEN inhibits rat hepatic stellate cell activation. 2009. J Gastroenterol. 44(8):847-55. PMCID: PMC2790377SK Huang, ES White, SH Wettlaufer, H Grifka, CM Hogaboam, VJ Thannickal, JC Horowitz, M Peters-Golden. Prostaglandin E2 induces fibroblast apoptosis by modulating multiple survival pathways. 2009. FASEB J. 23(12):4317-26. PMCID: PMC2812040RL Sagana, M Yan, AM Cornett, JL Tsui, DA Stephenson, SK Huang, BB Moore, MN Ballinger, DM Aronoff, M Peters-Golden, and ES White. Phosphatase and tensin homologue on chromosome ten (PTEN) directs prostaglandin E2-mediated fibroblast responses via regulation of E prostanoid 2 receptor expression. 2009. J Biol Chem. 284(47): 32264-32271. PMCID: PMC2781639 TH Sisson, M Mendez, K Choi, N Subbotina, A Courey, A Cunningham, A Dave, JF Engelhardt, X Liu, ES White, VJ Thannickal, BB Moore, PJ Christensen, and RH Simon. Targeted injury of Type II alveolar epithelial cells induces pulmonary fibrosis. Am J Resp Crit Care Med. 2010. Feb 1;181(3):254-63. PMCID: PMC2817814.G Cai, A Zheng, Q Tang, ES White, C-F Chou, CL Gladson, MA Olman, and Q Ding. Downregulation of FAK-Related Non-Kinase Mediates the Migratory Phenotype of Human Fibrotic Lung Fibroblasts. Exp Cell Res. 2010. May 15;316(9):1600-9. PMCID: PMC2871958.KA Bauman, SH Wettlaufer, K Okunishi, KM Vannella, JS Stoolman, SK Huang, AJ Courey, ES White, CM Hogaboam, RH Simon, GB Toews, TH Sisson, BB Moore and M Peters-Golden. The anti-fibrotic actions of plasminogen activation occur via upregulation of prostaglandin E2 synthesis in humans and mice. J Clin Invest. 2010. 120(6):1950-1960. PMCID: PMC2877926ES White, RL Sagana, M Yan, AM Cornett, JL Tsui, CA Wilke, BB Moore, JD Ritzenthaler, J Roman, and AF Muro. Control of fibroblast fibronectin expression and alternative splicing via the PI3K/Akt/mTOR pathway. 2010. Exp Cell Res. Oct 1;316(16):2644-53. PMCID: PMC2924943 M Kohan, AF Muro, ES White, and N Berkman. EDA-fibronectin induces fibroblast differentiation via binding of the EDA segment to α4β7 integrin. 2010. FASEB J. Nov; 24(11):4503-12. *Cited in Faculty of 1000 Biology: evaluations for Kohan M et al FASEB J 2010 Jul 19 : id/4367956/evaluationSK Huang, AS Fisher, AM Scruggs, ES White, CM Hogaboam, BC Richardson, M Peters-Golden. Hypermethylation of PTGER2 Confers Prostaglandin E2 Resistance in Fibrotic Fibroblasts from Humans and Mice. 2010. Am J Pathol.177(5): 2245-55. PMCID: PMC2966784 BJ Murdock, AB Shreiner, RA McDonald, JJ Osterholzer, ES White, GB Toews, and GB Huffnagle. Co-evolution of TH1, TH2 and TH17 Responses During Repeated Pulmonary Exposure to Aspergillus fumigatus Conidia. 2011. Infect Immun. 79(1): 125-135. PMCID: PMC3019910 V Fabre, H Wu, S PondTor, H Coutinho, L Acosta, M Jiz, R Olveda, L Cheng, ES White, B Jarilla, ST McGarvey, JF Friedman, and JD Kurtis. TIMP-1 predicts risk of hepatic fibrosis in human Schistosoma japonicum infection. 2011. J Infect Dis. 203(5): 707-714. PMCID: PMC3072733LLN Hubbard, CA Wilke, ES White, and BB Moore. Myeloid-Specific Ablation of PTEN Restores Alveolar Macrophage Host Defense Against Pseudomonas aeruginosa Following Bone Marrow Transplantation. 2011. Am J Resp Cell Mol Biol. Nov; 45(5):1050-8. PMCID: PMC3361361ES White and AF Muro. Fibronectin splice variants: understanding their multiple roles in health and disease using engineered mouse models. 2011. IUBMB Life. Jul;63(7):538-46.ES White. Accessory cardiac bronchus. Images in Pulmonary, Critical Care, and Sleep Medicine. 2011. Am J Resp Crit Care Med. Mar 15;183(6):825. PMCID: PMC3081286AJ Booth, SC Wood, G Lu, AF Muro, ES White*, and DK Bishop*. Recipient-Derived EDA Fibronectin Promotes Cardiac Allograft Fibrosis. 2012. J Pathol. Mar; 226(4):609-18. *denotes co-senior authorship.JC Horowitz, IO Ajayi, P Kulasekaran, DS Rogers, JB White, SK Townsend, ES White, RS Nho, PDR Higgins, SK Huang, and TH Sisson. Survivin Expression Induced by Endothelin-1 Promotes Myofibroblast Resistance to Apoptosis. 2012. Int J Biochem Cell Biol. Jan; 44(1):158-69. PMCID: PMC3241828AB Shreiner, BJ Murdock, AS Akha, NR Falkowski, PJ Christensen, ES White, CM Hogaboam, and GB Huffnagle. Repeated exposure to Aspergillus fumigatus conidia results in CD4+ T cell-dependent and -independent pulmonary arterial remodeling in a mixed Th1/Th2/Th17 microenvironment that requires IL-4 and IL-10. 2012. Infect Immun. Jan; 80(1):388-97. PMCID: PMC3255686GA Yanik, S Mineishi, JE Levine, CL Kitko, ES White, MT Vander Lugt, AC Harris, T Braun, and KR Cooke. Soluble Tumor Necrosis Factor Receptor: Enbrel (etanercept) for Sub-Acute Pulmonary Dysfunction Following Allogeneic Stem Cell Transplantation. 2012. Biol Blood Marrow Transpl. Jul;18(7):1044-54. BJ Murdock, AB Shreiner, AS Akha, NR Falkowski, RA McDonald, ES White, GB Toews, and GB Huffnagle. IL-17 Drives Pulmonary Eosinophilia Following Repeated Aspergillus fumigatus Conidia Exposure. 2012. Infect Immun. Apr; 80(4):1424-36. PMCID: PMC3318426CH Serezani, S Kane, AI Medeiros, AM Cornett, SH Kim, MM Marques, SP Lee, C Lewis, E Bourdonnay, MN Ballinger, ES White, M Peters-Golden. PTEN Directly Activates the Actin Depolymerization Factor Cofilin-1 During PGE2-Mediated Inhibition of Phagocytosis of Fungi. 2012. Sci Signal. Feb 7. 5(210):ra12. PMCID: PMC3400468TH Sisson, TM Maher, IO Ajayi, JE King, PD Higgins, AJ Booth, RL Sagana, SK Huang, ES White, BB Moore, JC Horowitz. Increased survivin expression contributes to apoptosis-resistance in IPF fibroblasts. Adv Biosci Biotechnol. 2012 Oct;3(6A):657-664. PMCID: PMC3553664.AJ Booth, R Hadley, AM Cornett, AA Dreffs, SA Matthes, JL Tsui, K Weiss, JC Horowitz, VF Fiore, TH Barker, BB Moore, FJ Martinez, LE Niklason, ES White. Acellular Normal and Fibrotic Human Lung Matrices as a Culture System for In Vitro Investigation. 2012. Am J Resp Crit Care Med. Nov 1;186(9):866-76. PMCID: PMC3530219PK Naik, PD Bozyk, JK Bentley, AP Popova, CM Birch, CA Wilke, CD Fry, ES White, TH Sisson, N Tayob, B Carnemolla, KR Flaherty, MB Hershenson, S Murray, FJ Martinez, BB Moore and the COMET investigators. Periostin promotes fibrosis and predicts progression in patients with Idiopathic Pulmonary Fibrosis. 2012. Am J Physiol – Lung Cell Mol Phys. Dec;303(12):L1046-L1056. PMCID: PMC3532583CL Kitko, ES White, K Baird. Fibrotic and sclerotic manifestations of chronic graft-versus-host disease. Biol Blood Marrow Transplant. 2012. Jan; 18(1 Suppl):S46-52. PMCID: PMC3260451B Blazar, ES White, D Couriel. Understanding chronic GVHD from different angles. Biol Blood Marrow Transplant. 2012 Jan; 18(1 Suppl):S184-8. PMCID: PMC3551472IO Ajayi, TH Sisson, PDR Higgins, AJ Booth, RL Sagana, SK Huang, ES White, JE King, BB Moore, JC Horowitz. X-Linked Inhibitor of Apoptosis regulates lung fibroblast resistance to Fas-mediated apoptosis. 2013. Am J Resp Cell Mol Biol. Jul;49(1):86-95.SK Huang, AM Scruggs, J Donaghy, JC Horowitz, Z Zaslona, S Przybranowski, ES White and M Peters-Golden. Histone modifications are responsible for decreased Fas expression and apoptosis resistance in fibrotic lung fibroblasts. 2013. Cell Death and Disease. May 2;4:e621.EA McDonald, JF Friedman, S Sharma, L Acosta, S Pond-Tor, L Cheng, ES White, JD Kurtis. Schistosoma japonicum soluble egg antigens attenuate invasion in a first trimester human placental trophoblast model. 2013. PLoS Negl Trop Dis Jun 6;7(6):e2253.F Klingberg, B Hinz, and ES White. The Myofibroblast Matrix: Implications for Tissue Repair and Fibrosis. J Pathol. 2013. Jan;229(2):298-309.J Lu, L Auduong, ES White, X Yue. Upregulation of Heparan Sulfate 6-O-Sulfation in Idiopathic Pulmonary Fibrosis. 2014. Am J Resp Cell Mol Biol. Jan;50(1):106-14.M Ghaedi, EA Calle, JJ Mendez, AL Gard, J Balestrini, A Booth, PF Bove, L Gui, ES White, LE Niklason. Human iPS cell-derived alveolar epithelium repopulates lung extracellular matrix. 2013. J Clin Invest. Nov 1;123(11):4950-62. TS Blackwell, AM Tager, Z Borok, BB Moore, DA Schwartz, KJ Anstrom, Z Bar-Joseph, P Bitterman, MR Blackburn, W Bradford, KK Brown, HA Chapman, HR Collard, GP Cosgrove, R Deterding, R Doyle, KR Flaherty, CK Garcia, JS Hagood, CA Henke, E Herzog, CM Hogaboam, JC Horowitz, TE King Jr, JE Loyd, WE Lawson, CB Marsh, PW Noble, I Noth, D Sheppard, J Olsson, LA Ortiz, TG O'Riordan, TD Oury, G Raghu, J Roman, PJ Sime, TH Sisson, D Tschumperlin, SM Violette, TE Weaver, RG Wells, ES White, N Kaminski, FJ Martinez, TA Wynn, VJ Thannickal, JP Eu. Future Directions in Idiopathic Pulmonary Fibrosis Research: An NHLBI Workshop Report. 2014. Am J Respir Crit Care Med. Jan 15;189(2):214-22.EA McDonald, L Cheng, B Jarilla, MJ Sagliba, A Gonzal, AJ Amoylen, R Olveda, L Acosta, D Baylink, ES White, JF Friedman, JD Kurtis. Maternal infection with Schistosoma japonicum induces a pro-fibrotic response in neonates. Infect Immun. 2014 Jan;82(1):350-5Y Zhou, H Peng, HX Sun, XY Peng, C Tang, Y Gan, XC Chen, AM Mathur, B Hu, M Slade, RR Montgomery, AC Shaw, RJ Homer, ES White, CM Lee, MW Moore, M Gulati, CG Lee, JA Elias, EL Herzog. Chitinase 3-like 1 Suppresses Injury and Fibroproliferative Responses in Pulmonary Fibrosis. Sci Transl Med 2014 6, 240ra76.VJ Thannickal, CA Henke, JC Horowitz, PW Noble, J Roman, PJ Sime, Y Zhou, RG Wells, ES White, DJ Tschumperlin. Matrix Biology of Idiopathic Pulmonary Fibrosis: A Summary from a National Heart, Lung and Blood Institute Workshop. 2014. Am J Physiology: Lung Cell Mol Phys Jun;184(6):1643-51.MW Parker, D Rossi, M Peterson, K Smith, K Sikstr?m, ES White, JE Connett, CA Henke, O Larsson, PB Bitterman. Fibrotic extracellular matrix activates a profibrotic positive feedback loop. 2014. J Clin Invest. ?Apr 1;124(4):1622-35.MK Han, Y Zhou, S Murray, N Tayob, I Noth, VN Lama, BB Moore, ES White, KR Flaherty, GB Huffnagle, FJ Martinez for the COMET Investigators. Association Between Lung Microbiome and Disease Progression in IPF: A Prospective Cohort Study. 2014. Lancet Resp Med. Jul;2(7):548-56.F Luo, Y Zhuang, MD Sides, CG Sanchez, B Shan, ES White, JA Lasky. Arsenic trioxide inhibits transforming growth factor-β1-induced fibroblast to myofibroblast differentiation in vitro and bleomycin induced lung fibrosis in vivo. Resp Res. 2014. Apr 24;15(1):51.GA Yanik, MM Horowitz, DJ Weisdorf, BR Logan, VT Ho, RJ Soiffer, SL Carter, J Wu, JR Wingard, NL Difronzo, JL Ferrara, S Giralt, DK Madtes, R Drexler, ES White, KR Cooke. A Randomized Double-Blind, Placebo-Controlled Trial of Soluble Tumor Necrosis Factor Receptor: Enbrel (Etanercept) for the Treatment of Idiopathic Pneumonia Syndrome Following Allogeneic Stem Cell Transplantation. A Blood and Marrow Transplant Clinical Trials Network (BMT CTN) Protocol. 2014. Biol. Blood Marrow Transplant. Jun;20(6):858-64.Bhattacharyya S, Tamaki Z, Wang W, Hinchcliff M, Hoover P, Getsios S, White ES, Varga J. Fibronectin EDA Promotes Chronic Cutaneous Fibrosis Through Toll-Like Receptor Signaling. 2014. Sci Transl Med. 6, 232ra50.Penke LR, Huang SK, White ES, Peters-Golden M. Prostaglandin E2 Inhibits α-Smooth Muscle Actin Transcription During Myofibroblast Differentiation via Distinct Mechanisms of Modulation of Serum Response Factor and Myocardin-Related Transcription Factor-A. 2014. J Biol Chem. Jun 13;289(24):17151-17162.Berschneider B, Ellwanger DC, Baarsma HA, Thiel C, Shimbori C, White ES, Kolb M, Neth P, K?nigshoff M. miR-92a regulates TGF-β1-induced WISP1 expression in pulmonary fibrosis. 2014. Int J Biochem & Cell Biol. Jun 19;53C:432-441.ES White, KK Brown, HR Collard, CS Conoscenti, GP Cosgrove, KR Flaherty, JA Leff, FJ Martinez, J Roman, D Rose, S Violette, and N Kaminski. Open-Access Biorepository in Idiopathic Pulmonary Fibrosis: The Way Forward. 2014. Ann Am Thorac Soc. Oct;11(8):1171-5.BL Hogan, CE Barkauskas, HA Chapman, JA Epstein, R Jain, CC Hsia, L Niklason, E Calle, A Le, SH Randell, J Rock, M Snitow, M Krummel, BR Stripp, T Vu,?ES White, JA Whitsett, EE Morrisey. Repair and Regeneration of the Respiratory System: Complexity, Plasticity, and Mechanisms of Lung Stem Cell Function. 2014. Cell Stem Cell. Aug 7;15(2):123-138.SK Huang, AM Scruggs, RC McEachin, ES White, M Peters-Golden. Lung Fibroblasts from Patients with Idiopathic Pulmonary Fibrosis Exhibit Genome-Wide Differences in DNA Methylation Compared to Fibroblasts from Nonfibrotic Lung. 2014. PLOS ONE. Sep 12;9(9):e107055.GA Yanik, SA Grupp, MA Pulsipher, JE Levine, KR Schultz, DA Wall, B Langholz, CC Dvorak, K Alangaden, RK Goyal, ES White, JM Collura, MA Skeens, S Eid, E Pierce, KR Cooke. TNF receptor inhibitor therapy for children with idiopathic pneumonia syndrome (IPS). A joint Pediatric Blood and Marrow Transplant Consortium (PBMTC) and Children’s Oncology Group (COG) study (ASCT0521). 2015. Biol Blood Marrow Transplant. Jan;21(1):67-73.JA Kropski, JM Pritchett, DF Zoz, PF Crossno, C Markin, ET Garnett, AL Degryse, DB Mitchell, VV Polosukhin, OB Rickman, L Choi, DS Cheng, ME McConaha, BR Jones, LA Gleaves, FB McMahon, JA Worrell, JF Solus, LB Ware, JW Lee, PP Massion, R Zaynagetdinov,?ES White, JD Kurtis, JE Johnson, SD Groshong, LH Lancaster, LR Young, MP Steele, JA Phillips III, JD Cogan, JE Loyd, WE Lawson, TS Blackwell. Extensive Phenotyping of Individuals At-risk for Familial Interstitial Pneumonia Reveals Clues to the Pathogenesis of Interstitial Lung Disease. 2015. Am J Resp Crit Care Med. Feb 15;191(4):417-26.C Calhoun, P Shivshankar, M Saker, LB Sloane, CB Livi, ZD Sharp, CJ Orihuela, S Adnot, ES White, A Richardson, C Jourdan Le Saux. Senescent Cells Contribute to the Physiological Remodeling of Aged Lungs. 2015. J Gerontol: Biol Sci. 1-9. doi:10.1093/gerona/glu241TH Sisson, IO Ajayi, N Subbotina, AE Dodi, ES Rodansky, LN Chibucos, KK Kim, VG Keshamouni, ES White, Y Zhou, PD Higgins, SD Larsen, RR Neubig, JC Horowitz. Inhibition of Myocardin-Related Transcription Factor/Serum Response Factor Signaling Decreases Lung Fibrosis and Promotes Mesenchymal Cell Apoptosis. 2015. Am J Pathol. Apr;185(4):969-86. BR Dye, DR Hill, MAH Ferguson, Y-H Tsai, MS Nagy, R Dyal, JM Wells, CN Mayhew, R Nattiv, OD Klein, ES White, GH Deutsch, JR Spence. In vitro generation of human pluripotent stem cell derived lung organoids. 2015. eLife. 4:e05098.V Fiore, P Strane, A Bryskin, ES White, J Hagood, and TH Barker. Thy-1 binds integrin in cis and modulates ECM avidity, Fyn recruitment to cell-matrix adhesions, and fibroblast mechanotransduction. 2015. J Cell Biol. Oct 12;211(1):173-90.V Sontake, SK Shanmukhappa, BA DiPasquale, GB Reddy, M Medvedovic, WD Hardie, ES White, and SK Madala. Fibrocytes Regulate Wilms Tumor 1-Positive Cell Accumulation in Severe Fibrotic Lung Disease. 2015. J Immunol. Oct 15;195(8):3978-91.SR Finkbeiner, JJ Freeman, MM Wieck, W El-Nachef, CH Altheim, YH Tsai, S Huang, R Dyal,?ES White, TC Grikscheit, DH Teitelbaum, JR Spence. Generation of tissue-engineered small intestine using embryonic stem cell-derived human intestinal organoids. Biol Open. 2015 Oct 12. pii: bio.013235.SA Matthes, TJ LaRouere, JC Horowitz,?ES White. Plakoglobin expression in fibroblasts and its role in idiopathic pulmonary fibrosis. BMC Pulm Med. 2015 Nov 6;15:140.ES White, M Xia, S Murray, R Dyal, CM Flaherty, KR Flaherty, BB Moore, L Cheng, JD Kurtis, FJ Martinez. Plasma surfactant protein-D, matrix metalloproteinase-7, and osteopontin index distinguishes idiopathic pulmonary fibrosis from other interstitial lung diseases. 2015. Am J Resp Crit Care Med. In press.JL Balestrini, AL Gard, KA Gerhold, EC Wilcox, A Liu, J Schwan, AV Le, P Baevova, S Dimitrievska, L Zhao, S Sundaram, H Sun, L Rittié, R Dyal, TJ Broekelmann, RP Mecham, MA Schwartz, LE Niklason, ES White. Comparative Biology of Decellularized Lung Matrix: Implications of Species Mismatch in Regenerative Medicine. Biomaterials. In press.Articles Submitted for PublicationCompleted Publications: Non-Peer-Reviewed and EditorialsES White. Infliximab in Sarcoidosis: More questions or more answers? 2006. Am J Resp Crit Care Med. 174: 732-733. (Invited Editorial)ES White and I Noth. Update in Idiopathic Pulmonary Fibrosis Clinical Trials. 2010. CHEST Physician. 5(7): 12.ES Chen and ES White. Innate Pathways Shape Sarcoidosis Signaling: From Bugs to Drugs. Am J Resp Crit Care Med. 2011. 183(4): 425-427 (Invited Editorial). ES White. Update in Interstitial Lung Disease Clinical Trials. 2011. CHEST Physician. 6(7):18.ES White and AR Mantovani. Inflammation, Wound Repair, and Fibrosis: Reassessing the Spectrum of Tissue Injury and Resolution. J Pathol. 2013. Jan;229(2):141-4.ES White. Lung Extracellular Matrix and Fibroblast Function. 2015. Ann Am Thorac Soc. Thomas L. Petty Aspen Lung Conference Proceedings: Rebuilding the Injured Lung. 12, Supplement 1. March 1, 2015: S30-S33.VJ Thannickal, M Murthy, WE Balch, NS Chandel, S Meiners, O Eickelberg, M Selman, A Pardo, ES White, BD Levy, PJ Busse, RM Tuder, VB Antony, JI Sznajder, GRS Budinger. Blue Journal Conference. Aging and susceptibility to lung disease. Am J Respir Crit Care Med. 2015 Feb 1;191(3):261-9.CL Scudamore, EJ Soilleux, NA Karp, K Smith, R Poulsom, CS Herrington, MJ Day, CF Brayton, B Bolon, B Whitelaw,?ES White, JI Everitt, MJ Arends. Recommendations for Minimum Information for Publication of Experimental Pathology Data: MINPEPA Guidelines. J Pathol. 2015 Sep 21. doi: 10.1002/path.4642.MJ Arends,?ES White, CB Whitelaw. Animal and cellular models of human disease. J Pathol. 2015 Oct 20. doi: 10.1002/path.4662. Book ChaptersES White and TJ Standiford. The role of polymorphonuclear leukocytes in the pathogenesis of idiopathic pulmonary fibrosis. 2004. In Idiopathic Pulmonary Fibrosis, J. P. Lynch III, Ed. Lung Biology in Health and Disease Series, vol. 185. Claude Lenfant, Exec. Ed. Marcel Dekker. New York, NY. pp. 341-357.JP Lynch III and ES White. Pulmonary Sarcoidosis. 2005. Eur Resp Mon. 32: 105-129.ES White, DA Zisman, DT Keena, and JP Lynch, III. Corticosteroid therapy for sarcoidosis. 2006. In Sarcoidosis, R.P. Baughman, Ed. Lung Biology in Health and Disease Series, vol. 210. Claude Lenfant, Exec. Ed. Marcel Dekker. New York, NY. pp. 689-716.JP Lynch III, MC Fishbein, and ES White. Pulmonary Sarcoidosis. 2008. In Interstitial Pulmonary and Bronchiolar Disorders, J.P. Lynch, Ed. Lung Biology in Health and Disease Series, vol. 227. Informa Healthcare USA. New York, NY.SA Matthes, R Hadley, J Roman, and ES White: Comparative Biology of the Normal Lung Extracellular Matrix. In Comparative Biology of the Normal Lung, R. Parent, Ed. Elsevier, London, UK, 2015. 2nd Edition, 20, 387-402. Patient Education Materials1.PD Bozyk and ES White. Chapter 7. Brain and Nerves. 2013. In Sarcoidosis: A Primer. LS Efferen and CM Smith, Eds. American College of Chest Physicians Patient Education Guide.2.PD Bozyk and ES White. Chapter 12. Lungs. 2013. In Sarcoidosis: A Primer. LS Efferen and CM Smith, Eds. American College of Chest Physicians Patient Education Guide.Alternate MediaES White. Myofibroblast Differentiation by PTEN. 2006. Modern Aspects of Immunobiology. 20(5): 5.ES White. Sarcoidosis: diagnosis and management. 2014. Audio-Digest Internal Medicine. Volume 61, Issue 34. September 14, 2014. ISSN 0271-1303.Abstracts and Preliminary CommunicationsES White, J Fuller, and MR Gyetko. Role of the Urokinase Receptor (uPAR) in Monocyte Phagocytosis of Cryptococcus neoformans. Presented at University of Michigan Senior Residents Research Conference, Ann Arbor, MI. April, 1998. Oral Communication.ES White, SR Strom, and DA Arenberg. Non-small cell lung cancer cells actively recruit monocytes to the tumor compartment. Presented at University of Michigan Cancer Center Symposium, Ann Arbor, MI. December 1999. Poster Presentation.ES White, SR Strom, and DA Arenberg. Modulation of macrophage-derived angiogenic activity by extracellular matrix proteins. Presented at Experimental Biology Meeting, San Diego, CA. April 2000. Oral Communication.ES White, SR Strom, and DA Arenberg. In vitro interaction between non-small cell lung cancer cells and monocytes. Presented at American Thoracic Society, International Conference, Toronto, Ontario, Canada. May 2000. Poster Presentation.ES White, SR Strom, and DA Arenberg. Modulation of macrophage-derived angiogenic activity by extracellular matrix proteins. Presented at University of Michigan Internal Medicine Research Symposium, Ann Arbor, MI. June 2000. Poster Presentation.ES White, SR Strom, NL Wys, and DA Arenberg. Fibronectin is a key inducer of macrophage-derived angiogenic activity. Presented at American Association for Cancer Research Special Conference, Vail, CO. September 2000. Oral Communication.ES White, NL Wys, and DA Arenberg. Macrophage-fibronectin interaction, via 51 integrin, results in increased expression of angiogenic factors. Presented at University of Michigan Internal Medicine Research Symposium, Ann Arbor, MI. April 2001. Oral Communication.ES White, NL Wys, and DA Arenberg. Fibronectin binding, via 51-integrin, increases macrophage-derived angiogenic activity. Presented at American Thoracic Society, International Conference, San Francisco, California. May 2001. Oral Communication.DA Arenberg, NL Wys, and ES White. Migration Inhibitory Factor (MIF) expression in lung cancer promotes angiogenesis. Presented at American Thoracic Society, International Conference, San Francisco, California. May 2001. Poster Presentation.ES White, SL Carskadon, DL Livant, S Markwart, GB Toews, and DA Arenberg. Fibrotic-lung fibroblast invasion of basement membranes is modulated by PTEN. Presented at American Thoracic Society, International Conference, Atlanta, Georgia. May 2002. Poster Presentation.DA Arenberg, SL Carskadon, and ES White. Expression of macrophage migration inhibitory factor (MIF) in human non-small cell lung cancer (NSCLC). Presented at Midwest Meeting of the American Federation for Medical Research, Chicago, IL. September 2002. Poster Presentation.ES White, SL Carskadon, EG Dickie, and DA Arenberg. Basement membrane invasion by lung fibroblasts from IPF: Role of paxillin and pp125FAK. Presented at American Thoracic Society, International Conference, Seattle 2003. Oral Communication.ES White, SL Carskadon, EG Dickie, and DA Arenberg. Invasive behavior of lung fibroblasts from fibrotic diseases: Role of the 41 and 51 Integrins. Keystone Symposium B2 Cell Invasion and Migration, Breckenridge, CO 2003. Poster Presentation.DA Arenberg, ES White, and SL Carskadon. Macrophage Migration Inhibitory Factor (MIF) promotes chemokine mediated angiogenesis in lung cancer. Presented at American Thoracic Society, International Conference, 2003, Seattle, WA. Poster presentation.GA Yanik, JP Uberti, JLM Ferrara, ES White, BA Hellerstedt, TJ Standiford, KE Cooke. Etanercept for Sub-Acute Lung Injury Following Allogeneic Stem Cell Transplantation.. Presented at American Society of Hematology, Annual Scientific Meeting, 2003, San Diego, CA. Poster Presentation.ES White, DM Aronoff, DA Arenberg, RG Atrasz, EG Dickie, and M Peters-Golden. Prostaglandin E2 inhibition of fibroblast migration via EP2 receptor-mediated increase in PTEN activity. Presented at American Thoracic Society, International Conference, 2004, Orlando, FL. Poster Discussion.ES White, RG Atrasz, FE Baralle, and AF Muro. The EDA domain of fibronectin promotes development of pulmonary fibrosis by enhancing fibroblast adhesion and myofibroblast differentiation. Presented at American Thoracic Society, International Conference, 2005, San Diego, CA. Poster Discussion.ES White, RG Atrasz, B Hu, and SH Phan. Regulation of myofibroblast differentiation by protein phosphatase activity of the tumor suppressor PTEN. Presented at American Thoracic Society, International Conference, 2005, San Diego, CA. Poster Presentation.DM Aronoff, C Canetti, ES White, CH Serezani, and M Peters-Golden. Phosphatase and tensin homologue deleted on chromosome 10 mediates inhibitory effects of PGE2 on rat alveolar macrophage antimicrobial functions. Presented at American Thoracic Society, International Conference, 2005, San Diego, CA. Poster Presentation.ES White, RG Atrasz, CA Wilke, and BB Moore. Resveratrol Attenuates Experimental Lung Fibrosis by Inhibition of Myofibroblast Differentiation and Proliferation. Presented at American Thoracic Society, International Conference, 2006, San Diego, CA. Poster Presentation.MR McClelland, SL Carskadon, L Zhao, ES White, and DA Arenberg. Diversity and Plasticity of the Angiogenic Switch in Lung Cancer. Presented at American Thoracic Society, International Conference, 2006, San Diego, CA. Oral Presentation.ES White, RG Atrasz, C Marcinkiewicz, and AF Muro. Blockade of EIIIA Cellular Fibronectin Signaling by Disintegrins Attenuates Pulmonary Fibrosis. Presented at American Thoracic Society, International Conference, 2006, San Diego, CA. Poster Discussion. M Takashima, CJ Parsons, K Ikejima, S Watanabe, ES White, and RA Rippe. The tumor suppressor protein PTEN inhibits rat hepatic stellate cell activation, proliferation, and survival. Presented at American Association for the Study of Liver Diseases Meeting, October 27-31, 2006, Boston, MA. Poster Presentation.JL Tsui, RG Atrasz, and ES White. PTEN Regulation of Alternative Fibronectin Splicing. Presented at the 52nd Summer Biomedical Research Program at the University of Michigan, November 2, 2006. Ann Arbor, MI. Poster Presentation.AF Muro, FA Moretti, BB Moore, RG Atrasz, CA Wilke, J Tsui, C Marcinkiewicz, DA Arenberg, FE Baralle, and ES White. Development and Progression of Lung and Liver Fibrosis is Dependent on the Extra Type III Domain A of Fibronectin. Gordon Research Conference on Fibronectin, Integrins, and Related Molecules, April 22-27, 2007. Il Ciocco Lucca, Italy. Oral Presentation.PE Thomas, M Peters-Golden, ES White, VJ Thannickal, and Bethany B. Moore. PGE2 inhibition of TGF-β1 induced fibroblast to myofibroblast differentiation is SMAD-independent, but involves cell shape and adhesion-dependent signaling. University of Michigan 15th Annual Department of Internal Medicine Research Symposium, May 4th, 2007. Ann Arbor, MI. Poster Presentation.K Pearson, ES White, and DA Culver. Dramatic responses to infliximab in patients with severe CNS sarcoidosis failing cyclophosphamide and corticosteroids. Presented at CHEST 2007, Chicago IL. Oral Presentation.AB Shreiner, ES White, R McDonald, B Fields, PJ Christensen, and GB Huffnagle. Repeated Inhalation of Aspergillus fumigatus Conidia Induces an Allergic Airway Disease that Leads to Pronounced Arterial Remodeling in the Lung. American Society for Microbiology, 2008.R Sagana, M Yan, M Peters-Golden, and ES White. PTEN is required for PGE2 inhibition of α-SMA and collagen production in fibroblasts. American Thoracic Society International Conference 2008, Toronto, Ontario, Canada. Oral Presentation.ES White, RH Simon, BB Moore, M Peters-Golden, and VJ Thannickal. TGF-β1-induced epithelial-mesenchymal transition is inhibited by prostaglandin E2 via increased intracellular cAMP. American Thoracic Society International Conference 2008, Toronto, Ontario, Canada. Oral Presentation.ES White, BB Moore, FA Moretti, GB Toews, FE Baralle, D Sheppard, and AF Muro. An essential role for EDA fibronectin in lung fibrosis. American Thoracic Society International Conference 2008, Toronto, Ontario, Canada. Oral Presentation.ES White, BJ Murdock, and GB Huffnagle. Disruption of immune tolerance as a potential pathogenic mechanism in sarcoidosis. American Thoracic Society International Conference 2008, Toronto, Ontario, Canada. Oral Presentation.RC Carroll, MW MacEwen, A Wishwas, ES White, and JS Hagood. Thy-1 reverses myofibroblastic differentiation induced by absence of PTEN in lung fibroblasts. American Thoracic Society International Conference 2008, Toronto, Ontario, Canada. Oral Presentation.D Stephenson, R Sagana, M Yan, and ES White. PTEN is required for PGE2 inhibition of α-SMA and collagen production in fibroblasts. University of Michigan Internal Medicine Residents Research Symposium. Oral presentation, May 22nd, 2008. Ann Arbor, MI.J Maslak, D Kaul, J Connelly, S Mineishi, JE Levine, E Peres, C Kitko, S Choi, Y Khaled, O Krijanovski, S DiGiandomenico, E White, T Braun, P Reddy, A Pawarode, JLM Ferrara, and GA Yanik. Bronchoscopic evaluation of pulmonary complications in patients undergoing reduced-intensity versus full-intensity transplants. American Society of Hematology 2008. San Francisco, CA.ES White, RL Sagana, M Yan, JL Tsui, AM Cornett. Regulation of Fibronectin Alternative Splicing by PTEN. American Thoracic Society International Conference 2009, San Diego, CA. Oral Presentation.ES White, AM Cornett, M Yan, RL Sagana, JL Tsui, L Liaw. Osteopontin Is Necessary for EDA Fibronectin Production and Fibroblast Activation. American Thoracic Society International Conference 2009, San Diego, CA. Poster Presentation.RL Sagana, M Yan, AM Cornett, JL Tsui, M Peters-Golden, ES White. PTEN Directs PGE2-Mediated Fibroblast Responses Via Regulation of EP2 Receptor Expression. American Thoracic Society International Conference 2009, San Diego, CA. Poster Presentation.SK Huang, SH Wettlaufer, R Sagana, ES White, JC Horowitz, VJ Thannickal, M Peters-Golden. Activation of PTEN/Inhibition of Akt Is Responsible for the Pro-Apoptotic Effects of Prostaglandin E2 in Lung Fibroblasts. American Thoracic Society International Conference 2009, San Diego, CA. Poster Presentation.Q Ding, ES White, C Chou, CL Gladson, MA Olman. Dysregulated FRNK/FAK Axis Promotes Pro-Fibrotic Phenotype of Lung Fibroblast and Lung Fibrosis. American Thoracic Society International Conference 2009, San Diego, CA. Poster Presentation.ES White, AM Cornett, M Yan, RL Sagana, AJ Booth, DA Dahlgren, KR Flaherty, GB Toews, BB Moore, FJ Martinez. An Alternatively-Spliced Isoform of Fibronectin as a Potential Biomarker in Idiopathic Pulmonary Fibrosis. American Thoracic Society International Conference 2010, New Orleans, LA. Poster Discussion.ES White, AM Cornett, M Yan, RL Sagana, AJ Booth, DA Dahlgren, KR Flaherty, GB Toews, BB Moore, FJ Martinez. An Alternatively-Spliced Isoform of Fibronectin as a Potential Biomarker in Idiopathic Pulmonary Fibrosis. 18th Annual University of Michigan Department of Internal Medicine Research Symposium. May 14, 2010. Ann Arbor, MI. Poster Presentation.RL Sagana, AJ Booth, AM Cornett, M Yan, and ES White. PTEN Regulation in Idiopathic Pulmonary Fibrosis. Epigenetic Mechanisms in Transcription and Disease. University of Michigan Department of Biologic Chemistry. September 23, 2010. Ann Arbor, MI. Poster Presentation.G Yanik, ES White, S Mineishi, J Levine, T Braun, and KR Cooke. Tumor necrosis factor inhibition for the treatment of sub-acute lung injury following allogeneic stem cell transplantation. European Group for Blood and Marrow Transplantation 2011, Paris France.ES White, AM Cornett, L Cheng, AA Dreffs, M Yan, RL Sagana, AJ Booth, BB Moore, VN Lama, CM Hogaboam, SL Schmidt, GB Toews, KR Flaherty, FJ Martinez, and JD Kurtis. High-Throughput Plasma Biomarker Analysis in IPF Reveals An Extracellular Matrix Remodeling Signature. American Thoracic Society International Conference 2011, Denver, CO. Oral Presentation.AJ Booth, SC Wood, AF Muro, DK Bishop, ES White. Extra Domain A Fibronectin Promotes Fibrotic Remodeling in Chronic Cardiac Allograft Rejection. American Thoracic Society International Conference 2011, Denver, CO. Poster Presentation.AJ Booth, CJ Coley II, ES White. Decellularized Human Lung Slices Implicate the Extracellular Matrix in Directing Fibroblast Phenotypes. American Thoracic Society International Conference 2011, Denver, CO. Poster Discussion.RL Sagana, AJ Booth, AM Cornett, AA Dreffs, JL Tsui, M Yan, and ES White. Promoter Methylation Downregulates PTEN Expression in IPF Lung Fibroblasts. American Thoracic Society International Conference 2011, Denver, CO. Poster Presentation.RL Sagana, AJ Booth, AM Cornett, M Yan, and ES White. PTEN Regulation in Idiopathic Pulmonary Fibrosis. Environmental Epigenomics and Disease Susceptibility Keystone Symposium. March 30, 2011. Asheville, NC. Poster Presentation.AJ Booth, AM Cornett, AA Dreffs, R Hadley, and ES White. Fibroblast Responses to Decellularized Human Lung Slices Implicate The Extracellular Matrix In Directing Fibroblast Phenotypes. Pulmonary Fibrosis Foundation “IPF Summit.” December 1-2, 2011. Chicago, IL.ES White, AJ Booth, AM Cornett, R Hadley, KM Weiss, AA Dreffs, LE Niklason, and FJ Martinez. Decellularized human lung slices as a culture substrate to examine the role of ECM in lung fibrogenesis and regeneration. European Respiratory Society Lung Science Conference. “Rebuilding a diseased lung: Repair and regeneration.” March 30 – April 1, 2012. Estoril, Portugal. Poster Presentation. *Distinguished Poster Award RecipientES White, N Tayob, SK Murray, KR Flaherty, BB Moore, J Kurtis, and FJ Martinez on behalf of the COMET Investigators. A Peripheral Blood Extracellular Matrix Biomarker Signature Predicts Disease Progression in IPF. American Thoracic Society International Conference 2012, San Francisco, CA. Poster Presentation.JC Horowitz, O Ajayi, R Sagana, ES White, BB Moore, SK Huang, and TH Sisson. Expression of Inhibitor of Apoptosis proteins in normal and fibrotic lung fibroblasts. American Thoracic Society International Conference 2012, San Francisco, CA. Poster Presentation.S Bhattacharyya, Z Tamaki, W Wang, P Hoover, A Booth, A Dreffs, M Hinchcliff, F Fang, S Getsios, H Yin, ES White, J Varga. The endogenous TLR4 ligand Fibronectin-EDA is overexpressed in scleroderma and drives persistent fibrosis via TLR4: novel target for scleroderma therapy. American College of Rheumatology 2012, Washington, DC.S Abedin, G Yanik, J Magenau, A Pawarode, S Goldstein, C Kitko, ES White, DR Couriel. The Use of Early Spirometric Changes and IGF-1 Levels for the Detection of Patients At Risk for BOS. American Society for Blood and Marrow Transplantation Tandem Meetings 2013, Salt Lake City, Utah. Poster Presentation.C Kitko, R Saliba, SW Choi, P Reddy, SC Goldstein, J Magenau, A Pawarode, M Kennel, JE Levine, ES White, DR Couriel. Biomarkers of Extracellular Matrix Remodeling in Chronic GVHD. American Society for Blood and Marrow Transplantation Tandem Meetings 2013, Salt Lake City, Utah. Poster Presentation.C Kitko, R Saliba, SW Choi, P Reddy, SC Goldstein, J Magenau, A Pawarode, M Kennel, JE Levine, ES White, DR Couriel. Biomarkers of Extracellular Matrix Remodeling in Chronic GVHD. European Group For Blood and Marrow Transplantation 2013, London, UK. Oral Presentation.GA Yanik, VT Ho, M Horowitz, DJ Weisdorf, BR Logan, J Wu, RJ Soiffer, JR Wingard, JE Levine, JLM Ferrara, SA Giralt, ES White, SL?Carter, N DiFronzo, KR Cooke. Randomized, Double Blind, Placebo-Controlled Trial of a TNF inhibitor (etanercept) for the Treatment of Idiopathic Pneumonia Syndrome (IPS) after Allogeneic Stem Cell Transplant (SCT). A Blood and Marrow Transplant Clinical Trials Network (BMT CTN) Study. American Society for Blood and Marrow Transplantation Tandem Meetings 2013. Salt Lake City, Utah. Oral Presentation.GA Yanik, S Grupp, MA Pulsipher, JE Levine, KR Schultz, ES White, DA Wall, B Langholz, CC Dvorak, K Alangaden, KR Cooke. Competitive TNF Inhibitor (etanercept) for the Treatment of Idiopathic Pneumonia Syndrome (IPS) Following Allogeneic Stem Cell Transplantation (SCT). A Joint Pediatric Blood and Marrow Transplant Consortium (PBMTC) and Childrens Oncology Group (COG) Study. American Society for Blood and Marrow Transplantation Tandem Meetings 2013. Salt Lake City, Utah. Oral Presentation.J Lu, L Auduong, ES White, X Yue. Overexpression Of Heparan Sulfate 6-O-Sulfotransferases In Idiopathic Pulmonary Fibrosis. American Thoracic Society International Conference 2013, Philadelphia, PA. Poster Presentation.J Votava, J Belperio, EA Kazerooni, A Lagstein, JL Myers, RH Simon, TH Sisson, B Sundaram, ES White, D Zisman, KR Flaherty. Utility Of Transbronchial Biopsy Versus Surgical Lung Biopsy In The Diagnosis Of Patients With Suspected Idiopathic Interstitial Pneumonia. American Thoracic Society International Conference 2013, Philadelphia, PA. Poster Discussion.JP Scott, N Tayob, MK Han, FJ Martinez, S Murray, ES White, KR Flaherty. Clinical Outcomes In Patients With Idiopathic Pulmonary Fibrosis: Data From COMET. American Thoracic Society International Conference 2013, Philadelphia, PA. Poster Presentation.R Hadley, A Booth, A Cornett, ES White. Characterization Of Lung Epithelial Phenotypes In Cells Cultured Within Normal And Fibrotic Human Acellular Lung Matrices. American Thoracic Society International Conference 2013, Philadelphia, PA. Poster Discussion.S Matthes, T LaRouere, BB Moore, JC Horowitz, ES White. The Role Of Plakoglobin In Idiopathic Pulmonary Fibrosis. American Thoracic Society International Conference 2013, Philadelphia, PA. Poster Presentation.A Booth, Z Breslin, B Mitchell, ES White. TLR4 As A Receptor For EDA-Containing Fibronectin. American Thoracic Society International Conference 2013, Philadelphia, PA. Poster Presentation.Y Bauer, ES White, J Kurtis, FJ Martinez, B Renault, A Trebaul, P Groenen, S Roux, I Leconte, A Morganti, O Nayler. Serum Osteopontin, Type I Collagen Telopeptide, And Pro-Collagen I Carboxy-Terminal Peptide Are Potential Predictors Of Longitudinal DLCO Changes In Idiopathic Pulmonary Fibrosis. American Thoracic Society International Conference 2013, Philadelphia, PA. Poster Discussion.C Jourdan-Le Saux, P Shivshankar, C Calhoun, AM Cornett, LB Sloane, CJ Orihuela, ES White, A Richardson. Mammalian Target Of Rapamycin (mTOR) Signaling Pathway Mediated Age-Associated Senescence But Not Pro-Fibrotic Responses. American Thoracic Society International Conference 2013, Philadelphia, PA. Poster Discussion.VL Murthy, EP Ficaro, J Meden, ES White, JR Corbett. Relationships between Quantitative FDG PET Parameters, Treatment and Disease Activity in Cardiac Sarcoidosis. Society of Nuclear Medicine & Molecular Imaging Annual Meeting 2014, St. Louis, MO. Poster Presentation.O Garcia, A Petrosyan, G Turcatel, D Warburton, ES White, B Driscoll, L Perin. Acellular Normal Lung Matrices As A Long-term Human Amniotic Fluid Stem Cell Culture System. American Thoracic Society International Conference 2014, San Diego, CA. Poster Discussion.LRK Penke,?SK Huang,?SH Wettlaufer,?ES White, M Peters-Golden. Critical Roles Of Krupple-Like Factor 4 And Forkhead Box O3A In Regulating Lung Fibroblast Proliferation. American Thoracic Society International Conference 2014, San Diego, CA. Poster Presentation.B Oehrle,?G Burgstaller,?M Irmler,?S Dehmel,?A Cornett,?T Hwang,?J Beckers,?S Krauss-Etschmann,?ES White,?S Meiners,?O Eickelberg. Growth-Factor Driven Down-Regulation Of Secreted Frizzled-Related Protein 1 (Sfrp1) Augments Fibroblast Invasion. American Thoracic Society International Conference 2014, San Diego, CA. Poster Presentation.E Speelmon,?SK Huang, R Sagana,?ES White. No Evidence For Epigenetic Regulation Of PTEN In IPF Lung Fibroblasts. American Thoracic Society International Conference 2014, San Diego, CA. Poster Presentation.V Sontake, B DiPasquale, SK Shanmukhappa, GB Reddy, ES White, SK Madala. Fibrocyte-Driven Accumulation of Wilms Tumor 1-Positive Lung-Resident Stromal Cells in Severe Fibrotic Lung Disease. American Thoracic Society International Conference 2015, Denver, CO. Poster Discussion.ES White, M Xia, S Murray, R Dyal, M Wang, FJ Martinez, KR Flaherty, D Dahlgren, C Flaherty, L Cheng, JD Kurtis. Plasma Osteopontin, Surfactant Protein-D, and MMP-7 Distinguish IPF from Non-IPF Interstitial Lung Disease. American Thoracic Society International Conference 2015, Denver, CO. Poster Presentation.AM Scruggs, JC Horowitz, ES White, SK Huang. DNA Hypermethylation of CDKN2B Contributes to a Pro-Fibrotic Phenotype in IPF Fibroblasts. American Thoracic Society International Conference 2015, Denver, CO. Poster Presentation.Y Huang, S.-F Ma, R Vij, Y Zhou, S Murray, GB Huffnagle, JR Erb-Downward, KR Flaherty, BB Moore, ES White, T Zhou, YA Lussier, MK Han, FJ Martinez, JGN Garcia, I Noth. Integrated Analysis of Host Transcriptome with Microbial Community Structure in Idiopathic Pulmonary Fibrosis Patients. American Thoracic Society International Conference 2015, Denver, CO. Poster Discussion.ES White, R Hill, R Dyal, M Wang, K Hansen. Quantitative Proteomics Identifies Regional Differences in Lung Extracellular Matrix. American Thoracic Society International Conference 2015, Denver, CO. Poster Discussion.ES White, S Matthes, C Dobry, R Dyal, M Wang. Fibrotic Lung Matrix Drives Early Myofibroblast Differentiation but Inhibits Long-Term Contractility. American Thoracic Society International Conference 2015, Denver, CO. Poster Discussion.V Sontake, SK Shanmukhappa, B DiPasquale, G Bhanuprakash Reddy, ES White, SK Madala. Aberrant Activation of Wilms’ Tumor 1 Protein Regulates Pulmonary Fibrosis. American Thoracic Society International Conference 2016, San Francisco, CA. Poster Presentation.G Tjin, ES White, EPW Kable, JK Burgess. Inhibition of Lysyl Oxidase Enzyme Activity In Vitro Inhibits TGF-β Induced Collagen Remodeling in 3D Collagen Models. American Thoracic Society International Conference 2016, San Francisco, CA. Poster Presentation.ML Salisbury, M Xia, S Murray, EA Belloli, RA Beckford, JS Sheth, ES White, KR Flaherty. Treatment Destiny in Idiopathic Pulmonary Fibrosis Patients Following Approval of Two Drug Therapies. American Thoracic Society International Conference 2016, San Francisco, CA. Poster Discussion.DN O’Dwyer, S Ashley, M Xia, S Murray, E Grant, ES White, KR Flaherty, FJ Martinez, BB Moore. The Proteome Signature of Disease Progression in Idiopathic Pulmonary Fibrosis. American Thoracic Society International Conference 2016, San Francisco, CA. Poster Discussion.Y Bauer, ES White, S DeBernard, P Cornelisse, I Leconte, A Morganti, J Hoerner, S Roux, O Nayler. MMP-7 is a predictive biomarker of disease progression in patients with early diagnosis of Idiopathic Pulmonary Fibrosis. International Colloquium for Lung and Airway Fibrosis. Dublin, Ireland, 2016.DN O'Dwyer, K Norman, M Xia, S Murray, E Grant, ES White, KR Flaherty, FJ Martinez, K Arnold, BB Moore. The proteome signature of Idiopathic Pulmonary Fibrosis identifies distinct biological processes and molecular functions. International Colloquium for Lung and Airway Fibrosis. Dublin, Ireland, 2016.ES White, M Xia, S Murray, BB Moore, DN O'Dwyer, J Kurtis, FJ Martinez, KR Flaherty on behalf of the COMET Investigators. A 5-Analyte Biomarker Panel is Associated With 48-Week Progression-Free Survival in IPF. International Colloquium for Lung and Airway Fibrosis. Dublin, Ireland, 2016. ................
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