Microsoft Word - Keays Medical Group

In the final dose evaluation, 2 patients (not on dialysis) experienced adverse events (hypotension, nausea, low back pain) during administration of 400 mg over 2 hours (n=35).51 In contrast, a dose of 500 mg (diluted in 250 ml 0.9% NaCl) administered over 3 hours on 2 consecutive days in 108 patients (majority not on dialysis) was reported to ... ................
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