CHALLENGES WITH DEFINING CLINICAL MEANINGFULNESS IN CNS DISEASES - ACT-AD
4 | ACT-AD LINIAL MEANINGFULNESS IN DRUG DEVELOPMENT FOR EARLY ALZHEIMER’S DISEASE | NOVEMER, 2014 BEYOND EFFICACY IN ISOLATION “Suppose a well-done randomized clinical trial (RCT) reports a statistically significant difference between treatment (T) and control (C) groups, with p=.05, p=.01, even p=10-6.Should these results be ................
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