LABORATORY SPECIFIC STANDARD OPERATING …



SOP for: (check one) FORMCHECKBOX Process FORMCHECKBOX Hazardous Chemical FORMCHECKBOX Hazard Class of Chemicals Name of Procedure: Working with Corrosive ChemicalsApplies to Lab (name): Chamberland Research GroupSCI Room #: 313Prepared By: James Siegenthaler, Stephanie Conn, and Stephen ChamberlandDate: 8/30/12Revision: 9/4/12Special Notifications:Corrosive chemicals are substances that cause visible destruction and permanent changes to human skin when it comes in contact, and are highly corrosive to metals. Major classes are strong acids, bases, and dehydrating agents.Hazard Description:To fully understand the dange involved, asses the SDS of the chemical being utilized. Corrosives are highly toxic, cause skin damage and can react with other chemicals. Consult the SDS to be fully aware of the chemical being used. Protective Equipment:Lab coatProtective wrap-around gogglesTwo pairs of chemically resistant nitrile gloves. Though dexterity is quite limited, butyl rubber gloves can also be used. Consult the SDS of the chemical being used to ensure proper glove selection.Long pantsClose-toed shoesEngineering Controls:Work in the area designated with ample ventilation. Always use a fume hood with the chemical as far back in the hood as possible. It is important to have the hood sash as low as possible to minimize exposure to splashing, explosion, and fumes. If the chemical being used is highly reactive, use a secondary blast shield for protection.Special Handling or Storage Requirements: Consult each chemical’s SDS for special handling requirements. Proper storage of corrosive chemicals is essential. Separate reactive chemicals and store like chemicals together. Store acids together. Do not store acids and bases together. Separate organic acids from mineral acids. Liquid and solid corrosives should also be separated. Use specially designed corrosion-resistant cabinets for corrosive storage. Do not store the corrosives in high cabinets or high shelves without lips in case they leak or fall.Spill Response Procedure:Anticipate spills by having the appropriate clean up equipment on hand. Appropriate supplies for the particular chemical can be determined by consulting the SDS. Consult SDSs prior to usage of the corrosive material. A spill kit should be on hand with instructions for the proper neutralization of the liquid portion of the spill. If no kit is readily available, identify what you are working with and use the appropriate chemical to counteract the spill and neutralize the corrosive material. Never use paper towel on large spills, neutralize the spill with an inert material (i.e. sand or dry earth) and dispose of the neutralized material in the proper waste container. If the spill is too large to clean, back away to a safe location, and notify your coworkers and the PI for instructions.Decontamination/Waste Disposal:If the compound is spilled on the skin or in the eyes, wash the affected area with copious amount of water for 15 minutes and consult a physician.If the spill involves hydroflouric acid seek immediate medical attention. Always consult the SDS sheet prior to use. Hydrofluoric acid use requires special technique and the presence of calcium gluconate gel. HF and other fluoride sources should never come into contact with glass. Use plastic containers instead.Carefully clean the work area after removal of the corrosive with soap and water. Place all halogenated materials (i.e. bromine) into the halogenated organic waste container. Place aqueous waste in the aqueous waste containter.If the corrosive is neutralized, covered with sand or another dry inert material, place the material in the solid waste container and ask the Chemical Hygiene Officer for the proper instructions for disposal. Use a base (usually solid or a saturated aqueous solution of sodium bicarbonate, NaHCO3) to neutralize an acid, or dilute (1 M) hydrochloric acid (HCl) to neutralize an inorganic base.Special Emergency Procedures: If a large amount of the corrosive chemical spills, notify the PI and/or EH&S officer. If it seems likely that fumes from the chemical are hazardous and will not be contained by the fume hood, notify your coworkers, evacuate the lab immediately, and call 911.Procedure may be performed after normal working hours (M-F, 8-5)?Yes FORMCHECKBOX No FORMCHECKBOX Procedure may be left unattended?Yes FORMCHECKBOX No FORMCHECKBOX Step by Step Procedure:1. Ensure that the reaction flasks and all other required equipment are prepared prior to using the chemical.2. Remove the chemical from the corrosives cabinet. 3. Secure the bottle, if necessary, with a three-prong clamp attached to a ring stand or to the sturdy metal bars in the fume hood. 4. Have a beaker filled with a few milliliters of a non-reactive solvent (e.g., CH2Cl2 when using bromine, H2O when using sulfuric acid) to wash out syringes and other equipment (e.g., Pasteur pipets) used to transfer corrosive materials. 5. Remove the cap from the bottle. If the bottle has a Sure-seal, place the bottle under nitrogen before removing the solution. See the SOP “Using the manifold” before placing a bottle under nitrogen. 6. Draw out the chemical with a syringe or a pipet. If drawing out chemical with a syringe, do so carefully. (See the SOP “Using a syringe) 7. Slowly add corrosive material to reaction flask. Remember the mnemonics A&W, AA (add acid), or drop acid for adding an acid to water. Never add water to acid, it can explode.8. Wash the syringe and needle out by rinsing with the appropriate solvent several times. Add these rinses to the appropriate waste container.9. Put the corrosive chemical back into the appropriate corrosive cabinet immediately after the material has been secured.Approved By (PI) : Stephen Chamberland, Ph.D.Date: 9/4/12PI Signature: ___________________________________________________Date: ______________EH&S Signature: ________________________________________________Date: ______________ ................
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