Possible Side Effects of Sirolimus - National Cancer Institute



Possible Side Effects of Sirolimus (Table Version Date: October 1, 2019)COMMON, SOME MAY BE SERIOUSIn 100 people receiving Sirolimus, more than 20 and up to 100 may have:Chest painSwelling of the bodySwelling and redness of the throat and sinuses (might not be caused by infection) which may cause difficulty breathing and swallowingAnemia, kidney problems which may cause tiredness, may require blood transfusions, or may require dialysisBruising, bleedingInfectionSores in the mouth which may cause difficulty swallowingConstipation, diarrhea, nauseaPainHeadachesDizzinessFeverCold symptoms such as stuffy nose, sneezing, sore throatAcneOCCASIONAL, SOME MAY BE SERIOUSIn 100 people receiving Sirolimus, from 4 to 20 may have:Damage to the brain which may cause changes in thinking, confusion or memory lossBlood clot which may cause confusion, swelling, pain, shortness of breathInternal bleeding which may cause coughing up bloodScarring of the lungsNon-healing surgical siteNose bleedSevere blood infectionAllergic reaction which may cause rash, low blood pressure, wheezing, shortness of breath, swelling of the face or throatKidney damage which may require dialysisBlockage of the airway, which may cause cough, wheezingRARE, AND SERIOUSIn 100 people receiving Sirolimus, 3 or fewer may have:A new cancer resulting from treatment of earlier cancer ................
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