Possible Side Effects of Cyclophosphamide, Cytarabine IV ...
Possible Side Effects of Cyclophosphamide, Cytarabine IV or SQ; IT Methotrexate, Mercaptopurine (MP), Vincristine, and PEG L-asparaginase (Table Version Date: August 28, 2014)
|COMMON, SOME MAY BE SERIOUS |
|In 100 people receiving Cyclophosphamide, Cytarabine IV or SQ; IT Methotrexate, Mercaptopurine (MP), Vincristine, and PEG L-asparaginase, more than 20 and up |
|to 100 may have: |
|Hair loss |
|Diarrhea, constipation, nausea, vomiting, loss of appetite |
|Infection, especially when white blood cell count is low |
|Absence of menstrual period which may decrease the ability to have children |
|Blood in urine |
|Blood clot |
|Swelling and sores in the rectum which may cause rectal pain |
|Sores in mouth which may cause difficulty swallowing |
|Anemia which may cause tiredness, or may require blood transfusions |
|Fever |
|Damage to the liver which may cause belly pain, bleeding, yellowing of skin or eyes |
|Fatigue |
|Pain or redness at the site of injection |
|Numbness and tingling of fingers or toes |
|Headache, jaw pain and/or muscle pain |
|Weakness and difficulty walking |
|Chills |
|Pain |
|Swelling of the body |
|Blockage of the airway which may cause cough, wheezing |
|Hives, rash |
|OCCASIONAL, SOME MAY BE SERIOUS |
|In 100 people receiving Cyclophosphamide, Cytarabine IV or SQ; IT Methotrexate, Mercaptopurine (MP), Vincristine, and PEG L-asparaginase, from 4 to 20 may |
|have: |
|Damage to the bone marrow (irreversible) which may cause infection, bleeding, may require transfusions |
|Loss or absence of sperm which may lead to an inability to father children |
|Stuffy nose |
|Fluid around the heart |
|Bruising, bleeding |
|Allergic reaction which may cause rash, low blood pressure, wheezing, shortness of breath, swelling of the face or throat |
|Numbness and tingling of the arms and legs |
|Severe blood infection |
|Kidney damage which may cause swelling, may require dialysis |
|Chest pain |
|Swelling and redness of the eye |
|Drooping eyelids |
|Sores in stomach |
|Hoarseness |
|Abnormal heart beat |
|Night sweats |
|RARE, AND SERIOUS |
|In 100 people receiving Cyclophosphamide, Cytarabine IV or SQ; IT Methotrexate, Mercaptopurine (MP), Vincristine, and PEG L-asparaginase, 3 or fewer may have: |
|Severe skin rash with blisters and peeling which can involve mouth and other parts of the body |
|Damage to the heart or heart failure which may cause shortness of breath, swelling of ankles, cough or tiredness |
|A new cancer including cancer of bone marrow (leukemia) caused by chemotherapy |
|Swelling of the body including the brain which may cause dizziness, confusion |
|of the lungs |
|Damage to the pancreas causing abdominal pain |
|Damage or scarring of the lungs which may result in shortness of breath |
|Seizure |
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